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Page 1: IDirect HealthCheck Sep16 - NSE / BSE Share & Stock Market …content.icicidirect.com › ... › IDirect_HealthCheck_Sep16.pdf · 2016-09-21 · Summary of USFDA approvals for Aug,

ICICI Securities Ltd. | Retail Equity Research

September 21, 2016

Monthly Update

Syngene opens new centre; Domestic growth recovers… In a significant tie-up, Syngene has opened a dedicated centre for US based leading biologics dedicated player Amgen Inc. in Bangalore. This centre, christened as Syngene Amgen Research and Development Centre (SARC), will be Syngene’s fourth such exclusive R&D centre and the first for a biologics company. Syngene already operates dedicated R&D centres for Bristol-Myers Squibb (BMS), Abbott Nutrition (Abbott) and Baxter Inc. SARC will be staffed by a team of more than 100 Syngene scientists, working with Amgen researchers around the world on the discovery and development of innovative medicines. The Indian pharmaceutical market (IPM) grew 15% YoY to | 9643 crore for the month of August, the highest growth in nine months mainly due to recovery in volume growth (albeit on lower base) and seasonality benefit. The growth was largely driven by volumes increase – 9.1% followed by price hikes- 2.9% and new product launches- 2.9%. On a MAT basis, IPM growth stood at 10.5% YoY to | 102537 crore. On an innovation front, Glenmark has announced the discovery and initiation of investigating new drug (IND) enabling studies for a novel clinical development candidate, GBR 1372. GBR 1372 adds to Glenmark’s expanding oncology portfolio of biologics including GBR 1302 (HER2xCD3 bispecific antibody) and GBR 1342 (CD38xCD3 bispecific antibody) based on its proprietary BEAT technology. Glenmark is likely to file an IND with the USFDA in 2HFY18. Glenmark presently has a pipeline of six Novel Biologics Entity (NBE) and tow Novel chemical Entity (NCE) in various stages of preclinical and clinical development. Glenmark has entered into a tie-up with US based Particle Sciences, Inc. to develop and market a generic version of Celgene’s oncology injection Abraxane (paclitaxel protein (albumin)-bound particles for injectable suspension). As per the agreement, Glenmark has obtained global exclusive marketing and distribution rights of the product upon commercialization. Particle Sciences will develop this product exclusively for Glenmark. On a regulation front, Indoco’s Goa plant II (sterile and solid dosages facility) received six 483 observations from USFDA. Inspection was conducted between 31st August 31, 2016 to 4th September, 2016. The injectable ANDA filings triggered this inspection. In Mar 2016, Goa plant received establishment inspection report (EIR) for inspection conducted in July 2015. No red flag on earnings front; regulatory worries waning… Despite pricing pressure and client consolidation in the US, which were thought to be the significant headwinds post Q4FY16 numbers, most of the players (barring few) managed to expand volumes in Q1 thereby neutralising these headwinds. Regarding USFDA issues the Indian players have moved on and seem better prepared than 12-18 months ago as reflected by growing number of EIRs by the USFDA for Indian facilities. The Indian formulations also did reasonably well despite NLEM / FDC issues. We expect earnings momentum to continue on the back of incremental product launches in the US and likely positive outcome from the USFDA re-inspections besides normalising of Indian formulations growth. We expect healthcare universe revenue, EBITDA and PAT to grow at a CAGR of 12%, 13% and 16%, respectively, in FY16-18E. The growth will be steered by US (~13% CAGR over FY16-18E) and Indian formulations (~14% CAGR over FY16-18E).

Health CheckSector View

Positive

Index Performance as on September 21, 2016

Return (%) 1M 3M YTD 1Y

CNX 500 1.3 8.8 11.4 12.7

Nifty 1.3 6.8 10.5 10.0

NSE Pharma 1.2 10.4 -1.9 -7.7

Return (%)

Stocks Performance Mcap

Company 1M 3M YTD 1Y 21-Sep

Sun Pharma.Inds. -0.6 5.8 -5.0 -13.5 187445

Lupin -1.9 6.6 -15.9 -17.8 69689

Dr Reddy's Labs 4.7 3.4 1.4 -20.3 52244

Cipla 8.0 24.4 -7.4 -7.4 48323

Aurobindo Pharma 5.6 12.0 -7.8 13.5 47261

Cadila Health. 4.9 24.1 19.5 -1.6 40069

Divi's Lab. 2.3 19.0 15.1 19.0 35287

Torrent Pharma. 4.2 21.6 12.7 13.8 27360

Glenmark Pharma. 4.0 18.1 -2.4 -12.0 25394

Glaxosmit Pharma -10.0 -20.0 -15.2 -16.1 23806

Biocon 11.6 30.5 82.5 114.9 18911

Apollo Hospitals -5.8 0.4 -10.5 -3.8 18251

Ajanta Pharma -0.2 34.1 47.6 35.8 17298

Alembic Pharma 1.1 20.3 -6.2 -5.8 12310

Natco Pharma -0.8 26.9 10.0 41.2 11094

Jubilant Life 24.1 84.3 52.7 81.3 10007

Wockhardt 11.8 -1.0 -41.7 -35.4 9851

Syngene Int. 13.8 17.9 15.7 49.7 9641

Strides Arcolab 4.6 -5.2 -20.0 -14.1 9211

Pfizer 4.7 5.9 -15.3 -22.4 9140

Ipca Labs. 15.2 20.2 -20.3 -22.2 7457

Indoco Remedies 8.1 25.7 1.2 1.1 3051

Unichem Labs. -2.7 1.1 -1.6 -3.6 2389

Return (%)

MMarket cap in | crore

Price movement

4000

6000

8000

10000

12000

50006000700080009000

100001100012000130001400015000

Sep-15 Dec-15 Mar-16 Jun-16 Sep-16

CNX Pharma Nifty (RHS)

Research Analyst

Siddhant Khandekar [email protected] Mitesh Shah [email protected]

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ICICI Securities Ltd. | Retail Equity Research

Page 2

Regulatory approvals

Exhibit 1: Summary of USFDA approvals for Aug, 2016 [5

Company Drug Name Therapeutic Area Innovator company Generic Version of Market SizeSun Pharma Metformin Hydrochloride Anti-Diabetic Santarus Inc Glumetza US$ 1200 millionNatco Pharma Oseltamivir Phosphate Anti-Infective Roche Tamiflu US$ 403 millionAurobindo Pharma Linezolid Anti-Bacterial Harmacia Zyvox US$ 87 millionSun Pharm Buprenorphine Hydrochloride; Naloxone Hydrochloride Anti-Addictive Indivior Inc Suboxone NAAurobindo Pharma Galantamine Hydrobromide Anti-Alzheimer Janssen Pharma Razadyne NAGlenmark Pharma Triamcinolone Acetonide Dermatology NA NA US$ 4.4 millionAurobindo Pharma Esomeprazole Sodium GI Astrazeneca Nexium IV NADr Reddys Labs Paricalcitol Hormonal Abbvie Zemplar US$ 110 millionJubilant Felodipine Er Tablets CVS Astrazeneca Plendil NAAurobindo Pharma Omeprazole; Sodium Bicarbonate Gi Santarus Zegerid NAJubilant Telmisartan Tablets CVS Boehringer Ingelheim Pha Micardis US$ 250 millionCipla Trospium Chloride Cns Valeant Wellbutrin XL US$ 792 millionSun Pharm Morphine Sulfate Pain Management Purdue Pharma Ms Contin NADr Reddys Labs Nitroglycerin CVS Pfizer Nitrostat US$ 108 millionAjanta Pharma Olanzapine Cns Lilly Zyprexa NA

Company Drug Name Therapeutic Area Innovator company Generic Version of Market SizeTorrent Pharms Rosuvastatin Calcium CVS Astrazeneca Crestor NALupin Paroxetine Anti-Depressant Apotex Paxil NAAjanta Pharma Eletriptan Hydrobromide Pain Management Pfizer Relpax NA

Final Approvals

Tentative Approvals

CNS: Central Nervous System; CVS: Cardiovascular,GI: Gastro Intestinal, NA: Not available; Source: USFDA, ICICIdirect.com Research

M&As, Demergers, Tie-ups and JVs DRL to market three of Amgen’s Biological drugs in India DRL will be commercialising Amgen’s three biological drugs XGEVA (denosumab), Vectibix (panitumumab) and Prolia (denosumab) in India in the therapeutic areas of oncology and osteoporosis. Cadila partners Takeda for chikungunya vaccine Cadila health entered in to a strategic partnership with Japan's Takeda Pharma to develop vaccine for vector borne chikungunya. The agreement includes early stage development to the final commercialisation of the vaccine. As per management, there is currently no vaccine to prevent chikungunya virus infection. Glenmark Signs agreement with Particle Sciences For gAbraxane Glenmark Pharma entered into a strategic agreement with Particle Sciences, Inc. to develop and market a generic version of Celgene’s oncology injection Abraxane (paclitaxel protein (albumin)-bound particles for injectable suspension). As per the agreement, Glenmark has obtained global exclusive marketing and distribution rights of the product upon commercialization. Particle Sciences will develop this product exclusively for Glenmark, and shall receive certain milestone payments during various stages of the product’s development from Glenmark, including royalties on sales. Development of the product has been initiated for the US market and Glenmark intends to file the ANDA in FY19. The product will be subsequently filed in other key markets across the globe. Branded Abraxane marketed globally by Celgene has reported sales of US$ 967 million in CY15. Indoco acquires manufacturing plant at Baddi Indoco Remedies has acquired the manufacturing facility at Baddi from Micro Labs Ltd. The facility is spread over an area of 18000 sq mt, out of which 11,000 sq mt is the built-up area. It produces 4.3 billion tablets and 50

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ICICI Securities Ltd. | Retail Equity Research

Page 3

million capsules p.a. With this acquisition, Indoco will now have six facilities for formulations and three for APIs. Price cuts / New Launches / Recalls/Approvals Glenmark announces Initiation of IND studies for GBR 1372 Glenmark has announced the discovery and initiation of investigating new drug (IND) enabling studies for a novel clinical development candidate, GBR 1372. GBR 1372 is the third Bispecific Antibody and also Glenmark’s third clinical candidate targeting an oncology indication. Law suits / Court rulings / Settlements / Regulatory Issues

Indoco Goa Plant II received six observations from USFDA Indoco remedies’s Goa plant II (sterile and solid dosages facility) received six 483 observations from USFDA. Inspection was conducted between 31st August 31, 2016 to 4th September, 2016. The injectable ANDA filings triggered this inspection. As per the management, none of these observations are related to data integrity issue. It expects to complete the corrective and preventive actions within a period of 30 days. In Mar 2016, Goa plant received establishment inspection report (EIR) from USFDA for inspection conducted in July 2015. Taro Pharma under anti-trust scanner for price hike Taro Pharma has been summoned by the US Department of Justice (DOJ) over its pricing policy. The DOJ's investigation comes at a time when pharma companies in the US are being accused of exorbitantly increasing the price of essential medicines. US FDA completes Aurobindo's Unit IV audit The company's management has indicated that the USFDA has completed inspection of unit IV plant at Andhra Pradesh and issued 2-3 observations. As per the management, the observations are minor which should not impact the approval of pending products from the site. Aurobindo, Sun and Lupin recall drugs in the US Lupin Pharma is recalling 26436 bottles of Lisinopril Tablet from US due to deviation from current good manufacturing practice (CGMP). Sun Pharma is also recalling 12109 HDPE bottles of Carvediol Tablets due to Failed Impurities/Degradation Specifications. As per the report, all the recalls are fall under a class III recall category. Aurobindo is also recalling 23016 bottles of Pantoprazole Sodium Delayed-Release Tablets under Class II category due to received a market complaint stating the presence of one foreign tablet (Montelukast Sodium Chewable Tab 4mg) in the product bottle of Pantoprazole. Others

Syngene sets up R&D centre for Amgen in Bengaluru Syngene has announced the establishment of a dedicated centre for Amgen, Inc. in Bangalore. This centre, called Syngene Amgen Research and Development Centre (SARC), will be Syngene’s fourth such exclusive R&D centre and the first for a biologics company. Syngene already operates dedicated R&D centres for Bristol-Myers Squibb (BMS), Abbott Nutrition (Abbott) and Baxter Inc. SARC will be staffed by a team of more than 100 Syngene scientists, working with Amgen researchers around the world on the discovery and development of innovative medicines. Q1FY17 Results

Apollo Hospital- Lower occupancy, Ind AS hit margins Standalone revenues increased 12% YoY to | 1465 crore on the back of a 22% increase in pharmacy business to | 633 crore. Healthcare business grew 6% to | 833 crore. EBITDA margins declined 85 bps to 12.8% on the back of adverse product mix and Ind AS, which impacted EBITDA margins of healthcare services negatively by 130-140 bps. Adjusted net profit de-grew 18% to | 72 crore due to higher interest cost and lower EBITDA.

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Page 4

Exhibit 2: Patent litigations (12 months) [5

Month Innovator ANDA Filer Brand Name API Used for Sep-15 Jazz Pharma Lupin Xyrem Sodium Oxybate NarcolepsySep-15 Gilead Sciences Inc. Lupin Tamiflu Oseltamivir InfluenzaSep-15 Horizon Pharma Lupin Pennsaid Diclofenac OsteoarthritisSep-15 Bayer Pharma Alembic Pharma Staxyn Vardenafil Hydrochloride Sex StimulantOct-15 Merck Lupin Beyaz Drospirenone Birth controlOct-15 Salix Pharmaceuticals, Inc. Taro Pharma Moviprep Polyethylene glycol electrolyte soln Gastro IntestinalOct-15 Takeda Pharma Aurobindo Prevacid lansoprazole Stomach ulcersOct-15 Janssen Pharma Aurobindo Xarelto Rivaroxaban Blood ThinnerOct-15 Novartis Pharma Natco Pharma Gleevec Matinib Mesylate Anti-cancerOct-15 Otsuka Pharma Zydus Pharma Abilify Aripiprazole SchizophreniaOct-15 AstraZeneca Alembic Pharma Brilinta Ticagrelor CVSNov-15 AstraZeneca InvaGen Pharma Brilinta Ticagrelor CVSNov-15 Novartis Pharma Dr. Reddy's Labs Exelon Patch Rivastigmine DementiaNov-15 Allergan Aurobindo Pharma Acular LS Ketorolactromethamine Ocular PainNov-15 Shire Pharma Lupin Lialda Mesalamine Ulcerative ColitisNov-15 Dexcel Pharma Sun Pharma Omeprazole Omeprazole GINov-15 Dexcel Pharma Dr. Reddy's Labs Omeprazole Omeprazole GINov-15 Cephalon Inc. Aurobindo Pharma Nuvigili Modafinil CNSNov-15 Cosmo Techs Lupin Uceris Budesonide GINov-15 Pfizer Dr. Reddy's Labs Toviaz Fesoterodine UrotherapyNov-15 Vanda Pharma Lupin Fanapt Iloperidone SchizophreniaNov-15 Forest Labs InvaGen Pharma Viibryd Vilazodone Anti-depressantNov-15 Jazz Pharma Sun Pharma Xyrem Gamma-hydroxybutyric acid CNSNov-15 Otsuka Pharma Alkem Labs Abilify Aripiprazole SchizophreniaNov-15 Symed Labs Glenmark Pharma Zyvox Linezolid Anti-InfectiveDec-15 UCB Inc. InvaGen Pharma Zyrtec-D Cetirizine RespiratoryDec-15 Unimed Pharma Dr. Reddy's Labs Androgel Testosterone Low TestosteroneDec-15 Helsinn Healthcare Dr. Reddy's Labs Aloxi Palanosetron NauseaDec-15 Sanofi-Aventis Glenmark Pharma Multaq Dronedarone Atrial FibrillationDec-15 Otsuka Pharma Ajanta Pharma Abilify Aripiprazole SchizophreniaDec-15 Merz Pharma Taro Pharma Naftin Naftifine Hydrochloride Fungal InfectionJan-16 Dow Pharma Taro Pharma Onexton Cindamycin Phosphate and Benzoyl Peroxide AcneJan-16 Cubist Pharma Dr. Reddy's Labs Cubicin Daptomycin AntibioticFeb-16 Bayer Pharma InvaGen Pharma Xarelto Rivaroxaban Blood ThinnerFeb-16 Bristol Myers Squibb Cipla Reyataz Atazanavir HIVFeb-16 Janssen Products LP Lupin Prezista Darunavir HIVMar-16 Shire Canada Lupin Daliresp Roflumilast RespiratoryMar-16 Daiichi Sankyo Torrent Pharma Benicar Olmesartan Anti-depressantApr-16 Daiichi Sankyo Alembic Pharma Benicar Olmesartan Anti-depressantMay-16 Daiichi Sankyo Aurobindo Pharma Benicar Olmesartan Anti-depressantJun-16 Apicore Aurobindo Pharma LYMPHAZURIN isosulfan blue lymphatic imaging agentJun-16 UCB, Inc. Aurobindo Pharma VIMPAT lacosamide partial-onset seizuresJun-16 Gilead Aurobindo Pharma EMTRIVA emtricitabine HIVJun-16 Janssen Biotech Glenmark Pharma ZYTIGA abiraterone OncologyJun-16 Sanofi-Aventis Cadila Healthcare MOZOBIL plerixafor non-Hodgkin's lymphomaJul-16 Sanofi-Aventis Cadila Healthcare MOZOBIL plerixafor non-Hodgkin's lymphomaJul-16 Roche Cadila Aloxi palonosetron hydrochloride prevention of acute nausea Jul-16 AstraZeneca AB Aurobindo Nexium 24HR esomeprazole magnesium treatment of acid refluxJul-16 Hyperion Therapeutics Lupin RAVICTI Glycerol Phenylbutyrate urea cycle disordersJul-16 Gilead Sciences, Inc. Aurobindo Truvada emtricitabine / tenofovir disoproxil fumarate HIVAug-16 Lupin InvaGen Pharma Antara fenofibrate hypercholesterolemia; dyslipidemAug-16 Gilead Sciences Inc Hetero Complera Emtricitabine; Rilpivirine Hydrochloride; TenofoHIVAug-16 Shire LLC Alkem Lab Fosrenol lanthanum carbonate end stage renal diseaseAug-16 AbbVie Inc. Amgen Inc. Humira adalimumab immunosuppressantAug-16 Galderma Laboratories, LP SEEGPharm Metrogel metronidazole rosacea Aug-16 Reckitt Benckiser Inc. Sun Pharma Mucinex guaifenesin / pseudoephedrine hydrochloride bronchial congestionAug-16 Takeda Pharma Dexcel Pharma Prevacid lansoprazole stomach ulcersAug-16 Dexcel Aurobindo Prilosec Omeprazole HeartburnAug-16 Shionogi Inc Hi-Tech Pharmacal Ulesfia benzyl alcohol anti-parasiteAug-16 Nestle Skin Health Perrigo Co. MIRVASO brimonidine Dermatology

Source: Bloomberg, ICICIdirect.com Research

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Page 5

IPM grew 15% in Aug- highest growth in 9 months • The Indian pharmaceutical market (IPM) grew 15.3% YoY to | 9643

crore for the month of August. The growth was driven by volumes increase – 9.1%, price hikes- 2.9% and new product launches- 2.9% and.

• The (Fixed dosage combination) FDCs related market de-grew 11.5%. • Drugs under NLEM list increased 4.5% to |1101 crore while non-NLEM

drugs posted a robust growth of 17.3% to | 8141 crore. Volume growth in NLEM and Non-NLEM was 14.9% and 9.6% respectively.

• Among companies under I-Direct coverage, Indoco, IPCA and Unichem, glenmark, Alembic and Sun have registered robust growth of 33.7%, 28.0%, 26.4%, 20.9%, 20.5% and 20.3% respectively. DRL, Torrent, Ajanta, Lupin, Cipla and Cadila registered growth of 17.3%, 12.7%, 10.0%, 9.3%, 8.6% and 6.7% respectively.

• Therapy wise, 6 therapies have outpaced the IPM growth. Notable among them with growth rates- Anti-Malarials – 38.6%, Anti infective – 19.6%, Respiratory—32.3%, Anti Diabetic —19.0%, Pain/Analgesics – 15.4% and GI – 14.2%.

• In all, 340 new brands were launched in Aug-16. • On a MAT basis, IPM growth stood at 10.5% YoY to | 102537 crore.

Domestic companies have grown 17.1%, while MNC companies have grown 9.0% in Aug-2016.

Exhibit 3: Domestic formulations - growth trend

12.2 13

.7

10.6

9.8

8.8

15.8

23.0

13.1

10.1 12

.6

20

4.7 6.

7

14.9

-5

0

5

10

15

20

25

Jul-1

5

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market

[

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 4: Companies growth in domestic market in Aug, 2016

11.9

28.0

8.8 8.2

12.3 15.6

19.7

7.2

34.034.5

13.5

2.9 5.8

12.4

7.3

19.9

0

5

10

15

20

25

30

35

40

Ajan

ta

Alem

bic

Bioc

on

Cadil

a

Cipla

DRL

Glen

mar

k

GSK P

harm

a

Indo

co

Ipca

Labs

Lupin

Nova

rtis

Pfize

r

Sun P

harm

a

Torre

nt

Unich

em

(%)

Source: AIOCD data base, ICICIdirect.com Research

Therapy wise performance (| crore) Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)Anti-Infectives 1562 1306 19.6 1409 10.9GI 1138 997 14.2 1133 0.4Cardiac 1119 1002 11.6 1084 3.2Vitamins 848 761 11.4 824 2.9Anti Diabetic 800 672 19.0 755 5.9Respiratory 771 583 32.3 685 12.6Pain 694 602 15.4 650 6.9Derma 554 494 12.2 527 5.3Neuro 552 504 9.5 527 4.7Gynaecological 472 426 10.8 473 -0.2Vaccines 163 163 0.1 172 -5.1Ophthal 162 156 4.5 155 5.1Hormones 159 139 14.0 149 6.7Anti-Neoplastics 149 146 2.1 145 2.7Others 117 87 35.2 108 8.4Blood Related 111 102 8.4 107 3.2Urology 105 91 15.0 101 3.4Anti Malarials 77 56 38.6 60 28.1Sex Stimulants 48 42 14.4 48 -0.3Stomatologicals 43 38 13.4 43 -0.4 Source: AIOCD data base

Top brands in Indian pharma market Brand Company Therapy Aug' 16 Aug' 15 Gr. (%)Corex Pfizer Respiratory 315.6 261.7 20.6Spasmo Prox Wockhardt GI 308.8 234.4 31.8Lantus Sanofi Anti Diabetic 304.5 241.2 26.2Galvus Met Novartis Anti Diabetic 295.8 216.4 36.7Augmentin GSK Anti-Infectives 295.4 329.2 -10.3Clavam Alkem Anti-Infectives 255.9 221.7 15.4Volini Ranbaxy Pain 236.8 204.3 15.9Becosules Sun Pharma Vitamins 219.5 257.8 -14.9Pan Alkem GI 205.8 182.3 12.9Voveran Novartis Pain 205.1 161.0 27.3

Source: AIOCD data base Industry acute to chronic therapy ratio percentage…

Acute, 44636.31,

48.8%

Chronic, 28318.03,

31.0%Sub-

Chronic, 18529.19,

20.3%

Source: AIOCD data base ; As per AIOCD MAT Aug 2016

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Page 6

Sun Pharmaceuticals

Stock Performance

507090

110130150

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Sun Pharma

Source: NSE, ICICIdirect.com Research Exhibit 5: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8

13.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9 15.8

11.6 12.5

18.1

4.5

9.9

8.2

20.3

12.3

5.2

5.2

3.3

9.9 12

.4

0

5

10

15

20

25

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Sun Pharmaceutical Industries

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 6: Market share in Indian formulations market

8.3 8.3 8.38.6 8.7

8.9 8.9 9.0 8.8 8.9 8.9 8.8 8.7

6.0

6.6

7.2

7.8

8.4

9.0

9.6

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Sun Pharmaceutical Industries

Source: AIOCD data base, ICICIdirect.com Research * Included Ranbaxy’s sales

Exhibit 7: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Volini Pain 22.1 19.2 15.2 21.3 3.7

Gemer Anti Diabetic 17.4 12.3 41.5 16.3 7.0

Rosuvas Cardiac 17.0 13.0 30.3 16.1 5.1

Istamet Anti Diabetic 16.6 12.1 37.4 16.2 2.6

Levipil Neuro 14.3 11.7 22.7 14.3 0.4

Revital H Vitamins 14.3 10.2 40.2 13.7 4.8

Pantocid Gastro Intestinal 13.5 11.2 21.0 13.1 3.2

Susten Gynaecological 12.8 11.5 10.8 12.8 -0.2

Pantocid Dsr Gastro Intestinal 11.1 9.6 15.5 10.8 3.0

Mox Anti-Infectives 10.1 8.2 23.3 9.9 1.1

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 8: Contribution of therapies to domestic sales (MAT Aug’16)

z

Cardiac29%

Neuro 27%

Gastro Intestinal

19%

Anti-Infectives18%

Derma7%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 9: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Cardiac 153.6 120.4 27.6 146.0 5.2

Neuro 141.4 117.4 20.5 136.0 3.9

Gastro Intestinal 102.2 87.9 16.2 100.0 2.2

Anti-Infectives 96.5 86.8 11.2 90.8 6.2

Derma 41.0 32.7 25.4 73.1 -43.9

Anti Diabetic 76.3 61.6 23.9 57.3 33.0

Vitamins 35.4 28.6 23.7 38.2 -7.4

Pain 59.6 51.9 14.8 34.3 73.8

Respiratory 33.8 22.7 49.0 30.0 12.7

Gynaecological 29.9 28.2 6.0 30.3 -1.5

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 3376.53,

42.1%

Chronic, 3570.21,

44.5%

Sub-Chronic, 1072.35,

13.4%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

18%

9%

7%

10%

56%

Top 10 11 to 20 21 to 30 31 to 50 Others

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September 21, 2016

Cipla

Stock Performance

6080

100120140

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Cipla

Source: NSE, ICICIdirect.com Research

Exhibit 10: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8

13.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9 15.8

11.0

4.6

21.0

15.9

16.6

10.0 11

.5

3.5

2.0 6.

1

8.8

14.2

12.3

0

5

10

15

20

25

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Cipla

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 11: Market share in Indian formulations market

4.84.9 4.9

5.15.2

5.15.2

4.9

5.2

4.7 4.74.6

4.5

4.0

4.2

4.4

4.6

4.8

5.0

5.2

5.4

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Cipla

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 12: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Foracort Respiratory 16.5 15.3 7.8 16.3 1.6

Duolin Respiratory 12.4 9.4 31.5 10.8 15.0

Budecort Respiratory 12.0 11.0 9.1 12.3 -2.5

Seroflo Respiratory 11.4 10.7 6.7 10.9 5.1

Asthalin Respiratory 11.4 10.6 7.8 10.3 10.3

Montair Lc Respiratory 8.0 5.9 35.5 7.3 10.6

Aerocort Respiratory 8.0 7.8 2.0 7.7 3.8

Azee Anti-Infectives 7.6 7.7 -0.4 7.9 -3.5

Advent Anti-Infectives 7.3 5.5 32.6 5.4 35.0

Ibugesic Plus Pain 7.0 5.4 30.3 6.4 9.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 13: Contribution of therapies to domestic sales (MAT Aug’16)

Respiratory30%

Anti-Infectives27%

Cardiac12%

Gastro Intestinal

8%

Urology5%

Other18%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 14: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (% )

Respiratory 132.2 112.8 1 7.2 122.1 8.3

Ant i- Infectives 113.4 109.6 3.5 110.9 2.3

Cardiac 51.1 46.9 8.9 52.0 -1.7

Gastro Intest inal 37.5 32.3 1 6.0 38.2 -1.8

Urology 20.1 19.7 1.8 20.1 -0.1

Neuro 13.6 15.7 -1 3.6 13.2 3.1

Ophthal 13.4 13.8 -2.8 13.8 -2.8

Pain 15.8 13.6 1 6.0 14.8 6.9

Derma 12.0 10.9 9.4 11.1 8.0

V itamins 7.9 7.4 6.5 8.4 -5.5

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 2119.70,

46.5%

Chronic, 1877.72,

41.2% Sub-Chronic, 556.57, 12.2%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

25%

13%

8%11%

43%

Top 10 11 to 20 21 to 30 31 to 50 Others

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Page 8

Dr. Reddy’s Labs

Stock Performance) Stock Performance

6080

100120140

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Dr. Reddys

Source: NSE, ICICIdirect.com Research Exhibit 15: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8 13

.1

10.1 12

.6

7.0

4.7 8.

8

6.7

14.9

15.8

14.6

7.5

30.7

23.6 27

.4

26.5 31

.7

6.7

-1.4

4.1

1.5

4.3

15.6

-10

0

10

20

30

40

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Dr. Reddys Laboratories

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 16: Market share in Indian formulations market

2.32.2

2.3

2.5

2.72.6

2.2 2.2

2.3

2.2

2.6

2.3

2.3

2.1

2.2

2.3

2.4

2.5

2.6

2.7

2.8

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Dr. Reddys Laboratories

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 17: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Omez D Gastro Intestinal 9.1 7.2 26.1 8.6 5.7

Omez Gastro Intestinal 8.9 10.7 -16.7 9.4 -5.5

Peggrafeel Anti-Neoplastics 7.2 1.7 309.9 5.4 33.2

Grafeel Anti-Neoplastics 6.3 5.7 12.0 7.9 -20.1

Nise Pain 5.8 5.4 7.2 5.2 10.5

Atarax Respiratory 5.6 3.3 70.1 5.1 9.6

Econorm Gastro Intestinal 5.5 5.7 -4.2 6.5 -16.7

Docetere Anti-Neoplastics 5.3 2.5 112.9 4.1 28.5

Razo D Gastro Intestinal 5.2 4.4 19.3 4.7 11.3

Razo Gastro Intestinal 5.1 3.7 37.7 4.8 6.1

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 18: Contribution of therapies to domestic sales (MAT Aug’16)

Gastro Intestinal

21%

Cardiac14%

Anti-Neoplastics

11%Respiratory

9%

Anti-Infectives8%

Other37%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 19: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Gastro Intestinal 44.5 41.2 8.0 44.3 0.5

Cardiac 27.7 27.1 2.0 25.6 8.1

Anti-Neoplastics 35.6 26.0 36.9 28.8 23.7

Respiratory 21.5 15.3 40.8 18.7 14.6

Anti-Infectives 21.1 15.1 39.8 16.3 29.4

Pain 14.5 13.3 9.4 13.4 8.6

Derma 11.4 10.1 12.1 10.7 6.6

Anti Diabetic 13.5 12.3 9.5 12.7 5.9

Urology 8.7 7.2 20.0 8.3 4.1

Neuro 7.3 6.7 7.8 6.6 10.7

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 1053.63,

50.0%

Chronic, 648.79, 30.8%

Sub-Chronic, 405.29, 19.2%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

29%

16%9%

12%

34%

Top 10 11 to 20 21 to 30 31 to 50 Others

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Page 9

Lupin

Stock Performance

6080

100120140

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Lupin

Source: NSE, ICICIdirect.com Research

Exhibit 20: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8 13

.1

10.1 12

.6

7.0

4.7

8.8

14.9

20.9

12.1

21.8

7.2

14.5

12.9

18.4 20

.5

9.9 11.7

4.7

11.1 13

.5

6.7

15.8

-4

4

12

20

28

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Lupin

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 21: Market share in Indian formulations market

3.3 3.3 3.3 3.33.4 3.4 3.4 3.4

3.3 3.33.2 3.2 3.2

2.3

2.5

2.7

2.9

3.1

3.3

3.5

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Lupin

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 22: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Gluconorm-G Anti Diabetic 15.0 11.4 30.8 14.6 2.2

Budamate Respiratory 8.4 6.1 39.0 7.6 11.4

Tonact Cardiac 7.7 8.4 -8.1 7.5 3.6

Rablet-D Gastro Intestinal 5.2 4.7 12.1 5.4 -3.5

Rablet Gastro Intestinal 4.5 4.5 1.1 4.5 1.4

Tazar Anti-Infectives 4.2 3.5 20.2 3.8 10.0

Esiflo Respiratory 4.0 4.4 -7.5 3.6 11.4

Telekast-L Respiratory 4.0 3.4 18.9 4.2 -4.4

Cetil Anti-Infectives 3.9 3.4 14.2 4.2 -6.4

Ramistar Cardiac 3.7 4.3 -15.2 3.5 3.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 23: Contribution of therapies to domestic sales (MAT Aug’16)

Cardiac24%

Anti-Infectives21%

Respiratory13%

Anti Diabetic12%

Gastro Intestinal

8%

Other22%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 24: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Cardiac 71.9 70.0 2.8 68.5 5.0

Anti-Infectives 63.9 62.1 2.9 60.8 5.0

Respiratory 38.0 30.8 23.4 34.4 10.6

Anti Diabetic 38.2 29.5 29.4 36.9 3.5

Gastro Intestinal 25.4 23.0 10.2 25.1 1.3

Vitamins 15.8 16.8 -5.9 15.6 1.3

Neuro 14.4 14.0 2.9 13.8 4.4

Pain 13.2 12.8 3.3 12.7 3.4

Gynaecological 11.4 9.8 16.7 10.7 6.8

Ophthal 2.0 1.8 12.6 2.0 0.9

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 933.57, 31.3%Chronic, 1428.21,

47.9%

Sub-Chronic, 617.73, 20.7%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

20%

11%

9%13%

47%

Top 10 11 to 20 21 to 30 31 to 50 Others

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Page 10

Cadila Healthcare

Stock Performance

6080

100120140

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Cadila Healthcare

Source: NSE, ICICIdirect.com Research Exhibit 25: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8

13.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9 15.8

14.2 15

.8

24.9

6.3

12.7

7.6

12.8

8.4

4.1

7.0

2.1 6.

4 8.2

0

5

10

15

20

25

30

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Cadila Healthcare

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 26: Market share in Indian formulations market

3.93.9 3.9

3.9 3.9 3.94.0

4.14.0

3.93.8

3.7 3.6

3.43.53.63.73.83.94.04.14.2

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Cadila Healthcare

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 27: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Skinlite Derma 13.9 13.9 0.2 13.3 4.4

Mifegest Kit Gynaecological 9.4 11.2 -16.4 10.7 -12.8

Deriphyllin Respiratory 9.2 6.5 41.9 8.4 9.8

Pantodac Gastro Intestinal 9.1 8.0 13.6 10.5 -12.9

Atorva Cardiac 9.0 10.5 -13.8 8.4 7.3

Falcigo Anti Malarials 6.5 7.9 -17.7 5.7 14.4

Zyrop Blood Related 6.5 5.8 12.2 6.9 -6.5

Vivitra Anti-Neoplastics 5.7 0.0 NA 6.4 -10.3

Thrombophob Pain 5.6 4.7 20.0 5.0 12.8

Sovihep Anti-Infectives 5.5 5.2 6.9 5.2 6.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 28: Contribution of therapies to domestic sales (MAT Aug’16)

Cardiac16%

Gastro Intestinal

14%

Respiratory11%

Gynaecological10%Pain

10%

Other39%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 29: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Cardiac 52.8 54.3 -2.6 51.4 2.9

Gastro Intestinal 47.4 44.4 6.8 48.4 -2.0

Respiratory 38.5 31.3 22.7 33.9 13.4

Gynaecological 31.9 35.3 -9.7 32.8 -2.9

Pain 36.1 31.4 15.1 32.7 10.5

Derma 26.9 25.0 7.8 25.3 6.3

Anti-Infectives 30.9 27.1 14.2 28.0 10.4

Anti-Neoplastics 23.0 21.3 7.9 23.0 -0.3

Vitamins 17.5 13.3 30.9 16.7 4.4

Anti Malarials 8.3 10.1 -17.8 7.3 14.6

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 933.57, 31.3%Chronic, 1428.21,

47.9%

Sub-Chronic, 617.73, 20.7%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

20%

11%

9%13%

47%

Top 10 11 to 20 21 to 30 31 to 50 Others

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Page 11

GlaxoSmithKline

Stock Performance

6080

100120140

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma GSK Pharma

Source: NSE, ICICIdirect.com Research

Exhibit 30: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8 13

.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9

15.8

-1.1

1.2

21.2

4.5 6.9

4.7

2.2

-7.2

-9.5

0.3 -6

.7

6.4 7.2

-15

-10

-5

0

5

10

15

20

25

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Indian Pharma Market Glaxosmithkline Pharmaceuticals

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 31: Market share in Indian formulations market

3.33.4

3.53.4 3.4

3.3

3.1 3.13.0 3.0

2.9

3.03.0

2.4

2.6

2.8

3.0

3.2

3.4

3.6

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Glaxosmithkline Pharmaceuticals

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 32: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Augmentin Anti-Infectives 25.7 27.2 -5.6 20.9 22.8

Calpol Pain 23.5 14.9 57.8 23.4 0.7

Synflorix Vaccines 18.3 14.6 25.0 16.2 13.1

Zinetac Gastro Intestinal 13.1 12.6 3.4 14.8 -11.6

Ceftum Anti-Infectives 12.2 11.1 9.9 11.4 7.3

Eltroxin Hormones 11.6 11.3 2.8 12.2 -5.1

Betnovate C Derma 10.1 12.1 -16.6 9.2 9.6

Betnovate N Derma 8.6 12.2 -29.2 9.2 -5.6

Betnesol Hormones 8.6 8.0 7.4 8.1 6.0

T Bact Derma 8.1 7.9 3.2 9.3 -12.5

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 33: Contribution of therapies to domestic sales (MAT Aug’16) Anti-Infectives

23%

Derma18%

Vaccines15%

Pain 10%

Respiratory8%

Other26%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 34: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Anti-Infectives 66.7 66.1 0.9 61.2 9.0

Derma 45.4 53.3 -15.0 46.0 -1.4

Vaccines 43.2 34.6 24.6 39.9 8.2

Pain 34.5 25.5 35.4 34.9 -1.0

Respiratory 23.0 20.9 9.9 20.8 10.4

Hormones 20.9 20.1 4.4 21.0 -0.3

Vitamins 23.4 22.2 5.7 24.0 -2.6

Gastro Intestinal 14.9 15.2 -1.8 16.7 -10.7

Cardiac 4.5 6.1 -26.6 4.6 -3.3

Gynaecological 2.2 2.8 -21.5 3.4 -34.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 2117.94,

66.3%

Chronic, 411.83, 12.9%

Sub-Chronic, 664.88, 20.8%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

51%

16%

9%

10%

14%

Top 10 11 to 20 21 to 30 31 to 50 Others

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Page 12

Wockhardt

Stock Performance

050

100150200250300350400

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Wockhardt

Source: NSE, ICICIdirect.com Research Exhibit 35: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8 13

.1

10.1 12

.6

7.0

4.7 8.

8

6.7

14.9

15.8

24.7

38.3

2.5

42.6

50.5

29.8

9.9

5.5

4.9 9.

4

1.8

14.4

9.2

0

10

20

30

40

50

60Au

g-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Wockhardt

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 36: Market share in Indian formulations market

1.351.39 1.41 1.38

1.33 1.37 1.37 1.341.28 1.25 1.22

1.29

1.28

1.01.11.21.31.41.51.61.71.8

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Wockhardt

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 37: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Spasmo Proxyvon PluGastro Intestinal 27.0 22.9 18.1 25.6 5.4

Practin Vitamins 7.6 6.2 21.8 7.3 4.8

Tryptomer Neuro 5.7 5.8 -0.2 5.1 12.9

Wepox Blood Related 5.6 0.7 644.5 6.0 -6.3

Bro Zedex Respiratory 4.8 3.5 37.9 4.7 2.7

Methycobal Vitamins 4.5 4.6 -3.8 4.3 4.8

Biovac A Vaccines 4.1 5.5 -24.7 2.7 52.3

Zedex Respiratory 3.4 2.4 41.9 3.4 1.3

Biovac V Vaccines 3.4 5.7 -40.0 3.5 -1.4

Wosulin Anti Diabetic 2.7 2.0 32.7 2.3 15.5

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 38: Contribution of therapies to domestic sales (MAT Aug’16) Gastro Intestinal

25%

Vitamins 15%

Respiratory12%

Neuro 8%

Anti-Infectives7%

Other33%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 39: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Gastro Intestinal 29.4 25.2 16.5 28.1 4.5

Vitamins 19.4 17.9 8.5 18.5 5.3

Respiratory 15.7 10.4 51.7 15.4 2.2

Neuro 9.7 9.5 1.9 8.9 7.9

Anti-Infectives 8.6 8.7 -0.9 7.5 15.6

Anti Diabetic 8.0 7.0 14.9 7.2 11.3

Derma 8.3 7.4 12.1 7.4 12.6

Pain 6.3 8.4 -25.5 5.9 6.0

Vaccines 7.7 11.2 -31.4 6.2 24.2

Hormones 2.5 1.9 30.5 2.6 -3.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 803.34, 69.7%

Chronic, 223.03, 19.3%

Sub-Chronic, 126.85, 11.0%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

54%

15%

9%

8%

14%

Top 10 11 to 20 21 to 30 31 to 50 Others

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Page 13

Glenmark Pharmaceuticals

Stock Performance

6080

100120140160180200

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Glenmark

Source: NSE, ICICIdirect.com Research

Exhibit 40: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8 13

.1

10.1 12

.6

7.0

4.7 8.

8

6.7

14.9

15.828

.0

13.0

43.6

11.5

18.6

16.3 19

.6

14.8

8.6

8.9

7.1

15.8 19

.7

05

101520253035404550

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Indian Pharma Market Glenmark Pharmaceuticals

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 41: Market share in Indian formulations market

2.32.4

2.5 2.5

2.62.5

2.4 2.42.4

2.2

2.3 2.3

2.4

1.9

2.1

2.3

2.5

2.7

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Glenmark Pharmaceuticals

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 42: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Telma Cardiac 13.6 14.0 -3.0 12.5 9.1

Telma H Cardiac 12.9 11.2 16.1 11.9 8.7

Ascoril Plus Respiratory 11.4 7.1 59.8 10.0 14.1

Candid Derma 9.1 7.6 20.1 10.0 -9.1

Candid-B Derma 8.6 7.6 13.7 9.6 -10.5

Telma Am Cardiac 6.9 5.9 15.8 6.4 7.0

Ascoril Ls Respiratory 5.5 3.2 72.9 4.0 39.2

Onabet Derma 4.9 3.2 49.8 4.2 15.1

Zitamet Plus Anti Diabetic 3.8 0.0 NA 3.5 8.1

Lizolid Anti-Infectives 3.5 2.7 32.6 2.9 22.9

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 43: Contribution of therapies to domestic sales (MAT Aug’16)

Derma29%

Cardiac22%

Respiratory16%

Anti-Infectives13%

Anti Diabetic8%

Other12%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 44: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Derma 63.2 56.1 12.8 61.3 3.1

Cardiac 47.4 43.0 10.2 43.8 8.2

Respiratory 40.4 25.6 57.7 33.6 20.2

Anti-Infectives 36.9 28.1 31.4 32.0 15.5

Anti Diabetic 14.7 17.7 -17.1 13.7 6.7

Vitamins 5.2 5.7 -8.7 5.1 1.8

Gastro Intestinal 8.1 4.7 72.1 6.8 19.2

Gynaecological 5.9 4.7 26.3 5.9 -0.6

Pain 4.1 4.4 -7.2 3.9 5.8

Ophthal 4.4 3.9 15.2 3.9 14.4

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 844.70, 40.2%

Chronic, 781.54, 37.2%

Sub-Chronic, 473.14, 22.5%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

36%

12%10%

13%

29%

Top 10 11 to 20 21 to 30 31 to 50 Others

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Page 14

Torrent Pharmaceuticals

Stock Performance

4080

120160200

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Torrent Pharma

Source: NSE, ICICIdirect.com Research Exhibit 45: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8

13.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9 15.821.7

16.0

19.9

5.4

3.8

7.4 10

.2

2.4

-3.0

1.4

-2.7

2.4

7.3

-5

0

5

10

15

20

25

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Indian Pharma Market Torrent Pharmaceuticals

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 46: Market share in Indian formulations market

2.242.22

2.162.19

2.22

2.29

2.34

2.212.25

2.322.29

2.24

2.19

2.1

2.1

2.2

2.2

2.3

2.3

2.4

2.4

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Torrent Pharmaceuticals

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 47: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Shelcal Vitamins 17.5 14.5 20.4 17.6 -0.6

Chymoral Forte Pain 11.2 11.9 -5.6 10.6 6.2

Nikoran Cardiac 7.6 7.2 5.8 7.2 6.4

Azulix-Mf Anti Diabetic 6.1 4.5 36.9 5.7 7.1

Nebicard Cardiac 5.7 4.7 19.9 5.3 7.2

Dilzem Cardiac 5.4 4.9 10.9 5.5 -1.2

Nexpro Rd Gastro Intestinal 5.3 4.1 30.5 5.5 -2.9

Nexpro Gastro Intestinal 4.7 3.9 19.1 4.6 2.2

Shelcal Ct Vitamins 4.5 3.2 37.2 4.5 -0.3

Rozucor Cardiac 3.6 3.1 16.3 3.3 7.1

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 48: Contribution of therapies to domestic sales (MAT Aug’16)

Cardiac29%

Neuro 16%

Vitamins 16%

Gastro Intestinal

15%

Pain 8%

Other16%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 49: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Cardiac 58.6 54.3 8.1 56.7 3.4

Neuro 33.9 30.1 12.4 32.4 4.5

Vitamins 33.8 27.5 23.0 33.9 -0.2

Gastro Intestinal 31.9 26.8 18.8 32.0 -0.3

Pain 17.8 16.9 4.9 16.9 5.4

Anti Diabetic 13.8 10.9 26.9 13.0 6.0

Anti-Infectives 8.7 9.3 -7.0 7.9 9.1

Derma 5.9 4.4 35.5 5.6 4.9

Gynaecological 3.0 3.2 -5.5 2.9 6.5

Urology 1.0 0.8 33.1 1.0 -1.9

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 555.14, 26.0%

Chronic, 1069.36,

50.1% Sub-Chronic, 509.42, 23.9%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

33%

14%9%

12%

32%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

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Page 15

Ipca Laboratories

Stock Performance

5075

100125150

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Ipca

Source: NSE, ICICIdirect.com Research Exhibit 50: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8 13

.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9

15.8

3.0

3.5

25.8

6.3

11.8

11.5

3.7

4.0

27.7

9.1

1.5 3.3

34.5

0

5

10

15

20

25

30

35

40

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Ipca Laboratories

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 51: Market share in Indian formulations market

1.31.4 1.4

1.3 1.2 1.2 1.2 1.2 1.2 1.2 1.21.4

1.5

0.60.81.01.21.41.61.82.0

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Ipca Laboratories

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 52: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Zerodol P Pain 9.6 6.6 43.9 5.7 67.4

Rapither-Ab Anti Malarials 9.2 3.8 139.9 7.0 30.6

Zerodol Sp Pain 8.5 8.2 4.3 8.4 1.2

Larinate Anti Malarials 8.2 4.3 89.9 6.0 37.4

Lariago Anti Malarials 7.5 3.1 138.6 5.0 49.9

Hcqs Anti Malarials 5.1 4.9 3.0 5.2 -2.6

Lumerax Anti Malarials 4.6 3.0 55.7 3.4 36.8

Glycinorm M Anti Diabetic 3.3 2.8 20.0 3.6 -7.1

Folitrax Anti-Neoplastics 3.1 2.5 22.3 3.0 3.3

Malirid Anti Malarials 2.5 1.5 66.9 2.0 28.3

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 53: Contribution of therapies to domestic sales (MAT Aug’16)

Pain 25%

Anti Malarials20%

Cardiac17%

Gastro Intestinal

8%

Anti-Infectives6%

Other24%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 54: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Pain 34.6 29.0 19.3 29.8 16.4

Anti Malarials 39.4 22.5 75.0 30.7 28.4

Cardiac 19.2 18.2 5.3 18.9 1.5

Gastro Intestinal 9.4 8.9 5.5 9.6 -2.3

Anti-Infectives 8.6 7.5 14.1 7.3 17.6

Anti Diabetic 6.1 5.6 10.3 6.3 -3.1

Respiratory 5.7 4.4 30.2 4.8 20.1

Anti-Neoplastics 5.0 4.0 26.0 4.7 5.6

Neuro 5.0 4.1 21.9 4.4 13.7

Derma 4.1 3.2 30.0 3.9 6.6

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 797.43, 66.9%

Chronic, 325.51, 27.3%

Sub-Chronic, 68.40, 5.7%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

38%

16%11%

12%

23%

Top 10 11 to 20 21 to 30 31 to 50 Others

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Page 16

Biocon

Stock Performance

60

80

100

120

140

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16CNX Pharma Biocon

Source: NSE, ICICIdirect.com Research

Exhibit 55: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8 13

.1

10.1 12

.6

7.0

4.7 6.

7

14.9

15.8

7.3

-11.

2

8.810

.0

-0.8

5.2

5.3

11.3 14

.5

7.7 9.

4

3.5

0.1

8.8

-15

-10

-5

0

5

10

15

20

25

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Biocon

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 56: Market share in Indian formulations market

0.33

0.31

0.330.32

0.34

0.36

0.34

0.38

0.34 0.34 0.35

0.320.31

0.27

0.29

0.31

0.33

0.35

0.37

0.39

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Biocon

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 57: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Insugen Anti Diabetic 7.7 7.2 6.3 7.1 7.8

Basalog Anti Diabetic 5.6 4.7 18.6 5.5 2.6

Erypro Blood Related 2.4 2.0 19.2 2.3 1.8

Biomab Egfr Anti-Neoplastics 1.9 0.2 938.6 0.1 1284.8

Canmab Anti-Neoplastics 1.8 1.7 4.4 1.7 6.1

Abraxane Anti-Neoplastics 1.7 1.0 68.9 2.3 -27.7

Insugen R Anti Diabetic 1.5 1.5 4.3 1.4 13.0

Blisto Mf Anti Diabetic 1.3 1.4 -9.6 1.2 7.5

Insugen N Anti Diabetic 0.6 0.8 -19.4 0.5 32.0

Psorid Anti-Neoplastics 0.6 0.7 -10.4 0.7 -6.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 58: Contribution of therapies to domestic sales (MAT Aug’16)

Anti Diabetic59%

Anti-Neoplastics

23%

Blood Related6%

Cardiac5%

Derma3%

Other 4%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 59: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Anti Diabetic 17.9 16.9 6.3 16.8 6.5

Anti-Neoplastics 7.4 5.1 44.6 6.2 19.3

Blood Related 2.4 2.0 21.7 2.4 1.9

Cardiac 1.3 1.3 -5.8 1.2 2.2

Derma 0.7 0.7 0.9 0.8 -7.8

Anti-Infectives 0.5 0.7 -24.6 0.6 -16.1

Others 0.2 0.2 17.4 0.2 -4.5

Gastro Intestinal 0.1 0.4 -74.5 0.1 -13.2

Vitamins 0.1 0.2 -40.8 0.1 -16.3

Pain 0.0 0.0 3.8 0.1 -61.7

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 68.01, 20.9%

Chronic, 234.38, 72.0%

Sub-Chronic, 23.33, 7.2%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

78%10%

5%5%

2%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

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Page 17

Pfizer

Stock Performance

4080

120160200

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Pfizer

Source: NSE, ICICIdirect.com Research Exhibit 60: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8 13

.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9

15.8

18.5

8.9

25.0

3.3

1.6

-3.5

5.1

3.4

2.7 7.

2

-1.0

8.9 5.

8

-10

-5

0

5

10

15

20

25

30

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Indian Pharma Market Pfizer

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 61: Market share in Indian formulations market

2.932.90

2.932.90 2.91 2.92

2.832.88

2.95

2.84

2.732.79

2.72

2.4

2.6

2.8

3.0

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Pfizer

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 62: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Corex Respiratory 24.4 27.4 -11.0 24.1 1.1

Becosules Vitamins 20.8 21.7 -4.5 21.5 -3.2

Minipress Xl Cardiac 13.1 9.6 36.9 16.3 -19.9

Magnex Anti-Infectives 12.7 12.3 3.1 11.9 6.6

Gelusil Mps Gastro Intestinal 12.3 11.6 5.6 12.3 0.0

Dolonex Pain 12.1 11.4 5.7 12.8 -6.1

Mucaine Gastro Intestinal 10.5 8.9 17.3 10.2 2.5

Wysolone Hormones 10.4 9.0 15.1 9.6 7.8

Prevenar 13 Vaccines 7.1 3.0 133.8 6.0 17.8

Dalacin C Anti-Infectives 6.6 6.6 0.6 5.7 16.8

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 63: Contribution of therapies to domestic sales (MAT Aug’16)

Anti-Infectives16%

Respiratory14%

Gastro Intestinal

11%

Vitamins 10%Hormones

9%

Other40%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 64: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Anti-Infectives 37.7 39.6 -4.7 35.0 7.9

Respiratory 33.5 32.6 2.8 31.6 6.0

Gastro Intestinal 27.6 25.7 7.5 27.7 -0.5

Vitamins 27.3 27.5 -0.8 27.9 -2.1

Hormones 23.7 22.0 7.4 22.2 6.4

Gynaecological 21.1 17.8 18.9 20.8 1.6

Neuro 16.4 17.1 -4.3 14.8 10.4

Cardiac 19.1 15.3 24.4 21.9 -12.8

Pain 17.3 15.9 8.8 16.9 2.2

Vaccines 12.3 6.9 77.7 11.2 9.6

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 1754.51,

63.8%

Chronic, 433.18, 15.7%

Sub-Chronic, 564.23, 20.5%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

50%

19%

10%

10%

11%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

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Page 18

Novartis

Stock Performance

40

90

140

190

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Novartis India

Source: NSE, ICICIdirect.com Research

Exhibit 65: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8

13.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9 15.8

21.7

15.3

27.4

20.4

17.3

14.9

25.1

21.6

18.7

3.9

4.4

2.9

10.2

0

5

10

15

20

25

30

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Indian Pharma Market Novartis India

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 66: Market share in Indian formulations market

1.15 1.161.21

1.16 1.17 1.16 1.151.19 1.19

1.10 1.10

1.021.06

0.9

1.0

1.0

1.1

1.1

1.2

1.2

1.3

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Novartis India

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 67: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Galvus Met Anti Diabetic 27.0 24.7 9.2 26.6 1.2

Voveran Pain 19.7 14.9 32.7 18.6 6.1

Galvus Anti Diabetic 10.1 10.3 -2.6 9.6 5.0

Rabipur (Novartis) Vaccines 8.2 7.0 16.5 5.6 45.7

Tegrital Neuro 4.4 4.5 -2.5 4.2 6.2

Voveran Pain 3.5 3.1 13.7 3.4 3.5

Regestrone Gynaecological 2.5 2.9 -12.9 2.9 -14.1

Methergin Gynaecological 2.4 3.0 -20.6 2.3 3.8

Syntocinon Gynaecological 2.4 2.2 9.0 2.2 6.0

Pybactum Anti-Infectives 2.0 0.5 273.4 0.2 712.6

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 68: Contribution of therapies to domestic sales (MAT Aug’16)

Anti Diabetic35%

Pain 23%

Vitamins 10%

Vaccines9%

Gynaecological8%

Other15%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 69: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Anti Diabetic 37.6 35.7 5.3 36.8 2.2

Pain 24.6 19.8 24.5 23.4 5.3

Vitamins 8.8 9.9 -10.8 8.8 0.2

Vaccines 8.3 7.1 16.3 5.7 45.8

Gynaecological 7.4 8.3 -11.4 7.6 -2.8

Neuro 4.4 5.6 -20.5 4.2 6.2

Anti-Infectives 5.4 4.6 16.0 3.2 70.8

Respiratory 1.9 1.8 10.7 1.8 10.5

Anti-Neoplastics 0.5 0.5 2.5 0.4 33.7

Cardiac 0.7 1.2 -39.1 0.7 2.2

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 427.68, 42.6%

Chronic, 414.61, 41.3%

Sub-Chronic, 162.81, 16.2%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

79%

11%4%4%2%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

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Page 19

Unichem Laboratories

Stock Performance

70100130160

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Unichem Labs

Source: NSE, ICICIdirect.com Research

Exhibit 70: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8

13.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9 15.8

2.7

28.3

3.8

11.3

9.9

10.0

3.1

0.6

2.3

4.0

8.4

13.5

19.9

0

5

10

15

20

25

30

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Unichem Laboratories

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 71: Market share in Indian formulations market

0.84 0.820.84 0.85

0.89

0.94

0.89 0.90 0.90 0.920.94 0.950.92

0.80

0.90

1.00

1.10

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Unichem Laboratories

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 72: Top 10 brands performance (| crore)

Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Losar H Cardiac 8.4 6.2 36.6 8.3 1.3

Ampoxin Anti-Infectives 7.4 5.8 28.0 6.8 8.6

Losar Cardiac 5.9 5.0 16.7 5.6 5.9

Unienzyme Gastro Intestinal 5.5 4.6 18.7 5.3 3.5

Vizylac Gastro Intestinal 3.5 3.1 14.2 3.2 10.7

Arkamin Cardiac 2.1 1.2 86.0 2.1 0.1

Serta Neuro 2.0 1.6 22.3 1.9 7.6

Trika Neuro 1.9 2.1 -8.3 1.9 -1.4

Unistar (Unichem) Cardiac 1.7 1.4 23.8 1.6 9.4

Linox Anti-Infectives 1.7 0.9 90.4 1.5 8.6

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 73: Contribution of therapies to domestic sales (MAT Aug’16)

Cardiac42%

Anti-Infectives17%

Neuro 14%

Gastro Intestinal

12%

Pain 4% Other

11%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 74: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Cardiac 34.8 28.5 22.1 34.2 1.8

Anti-Infectives 16.3 12.3 32.9 14.9 9.8

Neuro 11.9 9.3 28.9 11.2 6.9

Gastro Intestinal 10.7 9.1 18.4 10.1 6.6

Pain 4.0 3.0 33.9 4.0 1.0

Anti Diabetic 3.8 2.2 70.8 3.5 10.1

Respiratory 2.2 1.7 30.7 2.1 6.3

Vitamins 2.1 1.9 9.9 1.9 6.9

Derma 2.0 1.4 42.4 1.8 13.1

Gynaecological 0.4 0.5 -25.4 0.4 -7.9

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 312.14, 37.5%

Chronic, 472.89, 56.7%

Sub-Chronic, 48.43, 5.8%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

33%

14%9%

12%

32%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

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Page 20

Indoco Remedies

Stock Performance

6080

100120140

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Indoco

Source: NSE, ICICIdirect.com Research

Exhibit 75: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8 13

.1

10.1 12

.6

7.0

4.7 8.

8

6.7

14.9

15.8

-1.3

-6.4

16.2

10.3

11.0

5.6

5.4

34.0

0.7

-0.9

5.2

11.5

40.9

-10

0

10

20

30

40

50

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Indian Pharma Market Indoco Remedies

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 76: Market share in Indian formulations market

0.7 0.7

0.7 0.70.7 0.7 0.7

0.7

0.60.7

0.7

0.8 0.8

0.6

0.7

0.7

0.8

0.8

0.9

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indoco Remedies

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 77: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Febrex Plus Respiratory 10.8 5.3 106.0 9.0 20.5

Oxipod Anti-Infectives 6.3 3.0 110.9 5.0 27.9

Cyclopam Gastro Intestinal 4.6 4.1 12.7 5.6 -17.0

Atm Anti-Infectives 3.7 2.4 54.6 3.0 20.9

Sensodent-K Stomatologicals 3.2 2.7 21.8 3.7 -12.5

Cital Urology 2.9 2.6 8.9 2.7 5.8

Cyclopam Gastro Intestinal 2.5 1.8 39.4 3.0 -17.2

Cloben G Derma 2.3 2.0 18.8 2.2 5.6

Karvol Plus Respiratory 2.2 1.5 48.1 1.9 14.4

Sensodent-Kf Stomatologicals 1.8 2.0 -8.3 2.1 -10.1

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 78: Contribution of therapies to domestic sales (MAT Aug’16) Respiratory

19%

Anti-Infectives19%

Stomatologicals

16%

Gastro Intestinal

14%

Vitamins 7%

Other25%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 79: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Respiratory 17.4 9.8 78.2 14.5 20.2

Anti-Infectives 16.7 10.5 58.1 13.8 20.3

Stomatologicals 10.5 9.2 13.8 11.7 -10.3

Gastro Intestinal 10.5 8.8 20.3 12.2 -13.8

Vitamins 5.5 4.3 26.4 5.3 3.0

Urology 3.3 3.0 11.8 3.2 6.1

Ophthal 3.5 3.1 13.5 3.1 12.6

Pain 3.0 2.4 23.9 3.0 -0.2

Derma 3.1 2.6 17.2 2.9 4.5

Anti Diabetic 2.2 1.8 17.9 2.2 -0.7

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 547.10, 81.8%

Chronic, 43.70, 6.5%

Sub-Chronic, 77.72, 11.6%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

48%

15%

9%

10%

18%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

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Page 21

Ajanta Pharmaceuticals

Stock Performance

4090

140190240290

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Ajanta

Source: NSE, ICICIdirect.com Research

Exhibit 80: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8

13.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9 15.8

18.3

9.9

6.5 7.

6

12.6

14.3

6.9

10.5

7.6

13.1

11.4

10.9 11

.9

0

5

10

15

20

25

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Indian Pharma Market Ajanta Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 81: Market share in Indian formulations market

0.48

0.460.45

0.51 0.51

0.490.50

0.48 0.48

0.51 0.50

0.460.46

0.4

0.4

0.4

0.5

0.5

0.5

0.5

Aug

-15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Ajanta Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 82: Top 10 brands performance (| crore) Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Met Xl Cardiac 4.4 3.9 11.7 4.3 1.3

Melacare Derma 3.2 3.4 -6.6 3.8 -16.4

Atorfit Cv Cardiac 3.1 3.3 -3.6 2.9 9.2

Rosufit Cv Cardiac 1.6 1.1 44.4 1.4 13.5

Feburic Pain 1.4 1.3 13.8 1.3 10.1

Soft Drops Ophthal 1.3 1.2 5.6 1.4 -4.1

Met Xl Am Cardiac 1.2 0.9 33.4 1.2 6.6

Cinod Cardiac 1.0 0.7 34.2 0.9 15.7

Rosutor Gold Cardiac 0.9 0.6 44.6 0.9 -1.8

Peroclin Derma 0.8 0.8 1.4 0.7 12.1

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 83: Contribution of therapies to domestic sales (MAT Aug’16)

Cardiac34%

Ophthal 24%Derma

22%

Vitamins 6%

Pain 5%

Others9%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 84: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)

Cardiac 16.2 13.7 17.9 15.2 6.7

Ophthal 10.2 9.6 5.4 10.2 -0.5

Derma 8.9 8.7 2.7 8.9 -0.1

Vitamins 2.2 2.5 -13.3 2.0 8.2

Pain 2.2 2.2 -0.3 2.0 6.0

Gastro Intestinal 1.0 1.1 -8.9 0.9 4.1

Neuro 1.0 0.8 12.9 0.8 12.5

Anti-Infectives 1.0 0.7 40.7 0.8 19.6

Anti Diabetic 0.8 0.0 1850.1 0.7 14.5

Respiratory 0.3 0.3 -3.6 0.3 9.3

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 176.88, 39.8%

Chronic, 215.14, 48.4%

Sub-Chronic, 52.76, 11.9%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

42%

12%10%

13%

23%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

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Page 22

Alembic Pharmaceuticals

Stock Performance

406080

100120140160180200

Sep-15 Nov-15 Jan-16 Mar-16 May-16 Jul-16 Sep-16

CNX Pharma Alembic Pharma

Source: NSE, ICICIdirect.com Research

Exhibit 85: Company growth vis-à-vis Indian pharma market growth

13.7

10.6

23.0

9.8

13.1

10.1 12

.6

7.0

4.7

8.8

6.7

14.9

15.8

21.3

6.0

31.5

19.0

8.1

24.1

23.3

13.7

5.6

11.3

11.4

29.3

28.0

0

5

10

15

20

25

30

35A

ug-1

5

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

(%)

Indian Pharma Market Alembic Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 86: Market share in Indian formulations market

1.411.42 1.44

1.49 1.49 1.49

1.43

1.36

1.31 1.301.32

1.431.47

1.2

1.3

1.3

1.4

1.4

1.5

1.5

1.6

Aug-

15

Sep-

15

Oct-1

5

Nov

-15

Dec-

15

Jan-

16

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

(%)

Alembic Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 87: Top 10 brands performance (| crore)

Brand Therapy Aug' 16 Aug' 15 Var. (%) July' 16 Var. (%)

Azithral Anti-Infectives 14.3 11.6 23.8 12.1 18.9

Althrocin Anti-Infectives 8.9 8.3 6.9 8.5 4.5

Roxid Anti-Infectives 5.7 4.7 21.2 4.6 25.3

Gestofit Gynaecological 5.1 4.4 17.3 5.4 -5.4

Wikoryl Respiratory 5.1 2.9 72.8 4.2 21.0

Ulgel Gastro Intestinal 3.4 3.3 3.2 3.4 0.4

Rekool D Gastro Intestinal 2.9 3.1 -4.3 3.1 -4.9

Richar Gynaecological 2.7 2.0 34.8 2.7 2.1

Glisen Mf Anti Diabetic 2.3 2.2 4.3 2.3 -1.8

Rekool Gastro Intestinal 2.1 2.2 -5.1 2.3 -9.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 88: Contribution of therapies to domestic sales (MAT Aug’16)

Anti-Infectives23%

Cardiac14%Gastro

Intestinal14%

Respiratory13%

Gynaecological11%

Other25%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 89: Therapy wise performance (| crore)

Therapy Aug' 16 Aug' 15 YoY (%) July' 16 MoM (%)Anti-Infectives 34.5 29.3 17.7 29.7 16.1Cardiac 18.8 15.8 19.3 18.1 3.7Gastro Intestinal 18.7 17.6 6.5 18.8 -0.8Respiratory 19.4 13.6 41.9 15.8 22.3Gynaecological 14.9 12.5 19.9 14.8 0.7Vitamins 11.0 8.6 27.7 11.1 -0.4Anti Diabetic 9.0 6.6 37.6 8.7 3.3Pain 5.1 4.3 18.9 4.6 11.4Urology 3.1 2.1 46.5 2.8 9.5Derma 2.3 2.6 -13.2 2.1 5.9

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (MAT Aug’16)

Acute, 784.06, 63.8%

Chronic 231.46, 18.8%

Sub-Chronic 214.35, 17.4%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Aug’16)

42%

12%10%

13%

23%

Top 10 11 to 20 21 to 30 31 to 50 Others

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Page 23

Exhibit 90: One year forward P/E of CNX Pharma vs. Sensex

0

5

10

15

20

25

30

35

40

45

Sep-

06

Mar

-07

Sep-

07

Mar

-08

Sep-

08

Mar

-09

Sep-

09

Mar

-10

Sep-

10

Mar

-11

Sep-

11

Mar

-12

Sep-

12

Mar

-13

Sep-

13

Mar

-14

Sep-

14

Mar

-15

Sep-

15

Mar

-16

Sep-

16

x

CNX Pharma Sensex

[

Source: Company, ICICIdirect.com Research

ICICIdirect.com coverage universe (Healthcare) Company I-Direct CMP TP Rating M Cap

Code (|) (|) (| Cr) FY16 FY17E FY18E FY16 FY17E FY18E FY16 FY17E FY18E FY16 FY17E FY18E FY16 FY17E FY18E

Ajanta Pharma AJAPHA 1966 1,780 Hold 17298.3 45.4 52.8 63.6 43.3 37.2 30.9 29.9 25.0 21.2 42.9 37.1 35.0 34.2 30.2 28.2

Apollo Hospitals APOHOS 1299 1,440 Hold 18069.6 22.2 18.5 28.7 58.5 70.2 45.3 27.8 27.9 22.5 8.2 7.3 9.6 8.9 7.0 9.9

Aurobindo Pharma AURPHA 805 1,055 Buy 47126.6 33.9 41.3 48.0 23.7 19.5 16.8 25.0 20.5 17.7 23.3 24.6 25.5 28.1 26.0 23.5

Alembic Pharma ALEMPHA 652 620 Hold 12287.4 38.2 20.4 28.1 17.1 32.0 23.2 12.4 23.1 17.5 51.5 23.2 26.2 44.9 20.5 23.5

Biocon BIOCON 959 1,030 Buy 19184.0 22.5 33.3 38.4 42.6 28.8 25.0 11.5 8.7 7.0 9.1 13.1 14.8 11.1 14.7 15.0

Cadila Healthcare CADHEA 393 405 Buy 40238.2 15.0 15.8 20.3 26.3 24.9 19.4 17.1 17.5 13.8 26.7 22.9 26.8 28.6 24.7 25.6Cipla CIPLA 602 510 Hold 48405.4 18.5 17.6 25.4 32.5 34.2 23.7 20.3 18.5 13.7 12.0 11.1 15.2 12.5 10.8 13.8

Divi's Laboratories DIVLAB 1340 1,415 Buy 35575.4 41.8 45.1 54.5 32.1 29.7 24.6 24.7 21.8 18.1 30.7 29.2 29.8 25.9 23.3 23.4

Dr Reddy's Labs DRREDD 2974 2,875 Hold 53942.7 142.1 86.5 143.5 20.9 34.4 20.7 13.2 17.6 11.8 17.3 10.9 17.8 20.7 11.4 16.3

Glenmark Pharma GLEPHA 858 1,000 Buy 25565.9 32.2 41.4 49.8 26.7 20.7 17.2 17.8 14.9 12.1 16.2 18.7 20.6 21.2 21.7 20.9

Indoco Remedies INDREM 329 365 Buy 3035.9 9.0 13.6 19.4 36.6 24.3 17.0 17.9 13.5 10.4 12.5 17.3 23.4 14.2 18.3 21.7

Ipca Laboratories IPCLAB 590 605 Buy 7447.1 10.0 21.9 30.2 58.9 27.0 19.5 23.0 14.5 11.5 5.7 11.5 14.4 5.5 11.0 13.5

Jubilant Life Sciences VAMORG 591 635 Buy 9413.8 26.0 41.4 52.7 22.7 14.3 11.2 10.6 8.7 7.2 12.0 15.1 17.0 14.2 18.8 19.6

Lupin LUPIN 1549 1,890 Buy 69859.5 50.4 64.6 75.5 30.7 24.0 20.5 20.2 15.4 12.7 18.6 20.6 22.1 20.7 21.7 20.2

Natco Pharma NATPHA 647 700 Buy 11273.4 8.9 11.6 13.8 72.7 55.8 46.9 41.7 36.0 30.2 16.0 17.3 18.0 11.9 13.7 14.3

Sun Pharma SUNPHA 778 890 Buy 187341.7 23.4 29.9 35.5 33.2 26.1 21.9 20.9 16.8 14.2 18.6 20.7 21.2 18.0 19.3 19.2

Syngene International SYNINT 473 550 Buy 9454.0 11.1 15.8 18.7 42.7 29.9 25.3 26.1 20.8 16.7 13.2 17.4 19.3 21.0 23.6 22.3

Torrent Pharma TORPHA 1605 1,650 Buy 27159.8 107.8 68.0 74.9 14.9 23.6 21.4 10.5 16.6 15.6 46.7 28.5 27.5 53.8 27.0 24.3

Unichem Laboratories UNILAB 268 340 Buy 2434.4 12.3 15.3 21.1 21.8 17.6 12.7 14.9 12.0 8.6 13.8 15.7 18.9 11.7 12.9 15.5

RoE (%)EPS (|) PE(x) EV/EBITDA (x) RoCE (%)

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Page 24

RATING RATIONALE ICICIdirect.com endeavours to provide objective opinions and recommendations. ICICIdirect.com assigns ratings to its stocks according to their notional target price vs. current market price and then categorises them as Strong Buy, Buy, Add, Reduce and Sell. The performance horizon is two years unless specified and the notional target price is defined as the analysts' valuation for a stock. Sector view: Over weight compared to index Equal weight compared to index Under weight compared to index Index here refers to BSE 500

Pankaj Pandey Head – Research [email protected]

ICICIdirect.com Research Desk, ICICI Securities Limited, 1st Floor, Akruti Trade Centre, Road No. 7, MIDC, Andheri (East) Mumbai – 400 093

[email protected]

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Page 25

ANALYST CERTIFICATION We /I, Siddhant Khandekar CA-INTER Mitesh Shah MS (Finance) Research Analysts, authors and the names subscribed to this report, hereby certify that all of the views expressed in this research report accurately reflect our views about the subject issuer(s) or securities. We also certify that no part of our compensation was, is, or will be directly or indirectly related to the specific recommendation(s) or view(s) in this report.

Terms & conditions and other disclosures: ICICI Securities Limited is a Sebi registered Research Analyst having registration no. INH000000990. ICICI Securities Limited (ICICI Securities) is a full-service, integrated investment banking and is, inter alia, engaged in the business of stock brokering and distribution of financial products. ICICI Securities is a wholly-owned subsidiary of ICICI Bank which is India’s largest private sector bank and has its various subsidiaries engaged in businesses of housing finance, asset management, life insurance, general insurance, venture capital fund management, etc. (“associates”), the details in respect of which are available on www.icicibank.com. ICICI Securities is one of the leading merchant bankers/ underwriters of securities and participate in virtually all securities trading markets in India. We and our associates might have investment banking and other business relationship with a significant percentage of companies covered by our Investment Research Department. ICICI Securities generally prohibits its analysts, persons reporting to analysts and their relatives from maintaining a financial interest in the securities or derivatives of any companies that the analysts cover. The information and opinions in this report have been prepared by ICICI Securities and are subject to change without any notice. The report and information contained herein is strictly confidential and meant solely for the selected recipient and may not be altered in any way, transmitted to, copied or distributed, in part or in whole, to any other person or to the media or reproduced in any form, without prior written consent of ICICI Securities. 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