Watson Health Oncology - Brandenbranden.biz/.../Watson_Health_Oncology_Peter...IBM.pdfIBM Watson Health •Understands, reasons, learns and interacts •Extracts and derives meaning

1

Watson Health Oncology

Peter MortensenWatson Health Executive, Nordics

Proliferation of medical

literature is accelerating

Strategic Context: Healthcare knowledge sources have grown beyond human cognition…

~700 K new scientific

articles / year

Institutional Knowledge & Best Practices

6 Terabytes

Per lifetime

60%

Exogenous Factors

1,100 Terabytes

Generated per lifetime

0.4 Terabytes

Per lifetime

30%

Genomics Factors

10%

Clinical Factors

… and vast amounts of data that can have a great impact on our health remains untapped.

IBM Watson Health // SOURCE: ©2015 J.M. McGinnis et al., “The Case for More Active

Policy Attention to Health Promotion,” Health Affairs 21, no. 2 (2002):78–93

Data GeneratedHealth Determinents

IBM Watson Health

• Understands, reasons, learns and interacts

• Extracts and derives meaning from structured and unstructured content – at scale

• Provides analyses across vast arrays of criteria to transform decision-making

• Dynamically updates hypotheses based on variable chains of evidence

• Harnesses entire bodies of knowledge

It begins with the power of Watson

Page 5

© 2016 IBM Corporation 6

Surface actionable insights from a longitudinal patient record

Assesses relevant information for patient discovery. Analyze evidence for treatment options

Reduce clinician time to identify trials by matching relevant attributes of a patient to the trial inclusion and exclusion criteria

Assist clinicians to determine driver alterations, analyze pathways and identify potential interventions

Improve

efficiency and

effectiveness of

MTRB

Identify trials

Increase

enrollment

Increase efficiency

Leverage cognitive insights that assist in diagnosis of medical images

Reduce

misdiagnosis

Improve

adherence to

evidence

reduce care

disparity

InvestigationalTherapies (CTM)

Standard of Care(Oncology)

GenomicInterpretation

Medical ImagingInsights

Improve Trial

Strategy

Analyze

Populations

Enable research organizations to determine which studies to open. Identify trial candidates across a population

InvestigationalStudies (CTMi)

Efficiently

transform large

data sets to

evidence

Use local, network or global data sets to improve patient outcomes (cohorts, toxicity, adverse reactions, etc)

RWEInsights

Insights PatientRecord

Cognitive Platform for Oncology

Solution Landscape for Oncology

7IBM Confidential

Watson for Oncology

Offering

Encapsulates the knowledge and experience of the

specialists at MSK to enhance clinical decision making

Cancer is one of the leading causes of death in the world, and in the next decade, demand for treatments is

expected to grow by 42% creating a shortage of 1500 oncologists. Meanwhile, medical information is expected to

double every 73 days by 2020, making it even more difficult to keep up with the latest treatment options.

Benefit

Provides oncologists assistance to make more

informed, personalized treatment decisions

8IBM Confidential

Watson for Oncology helps medical oncologists and their care teams address these challenges

61 y/o woman s/p mastectomy

is here to discuss treatment

options for a recently diagnosed

4.2 cm grade 2 infiltrating ductal

carcinoma…

Prioritized Treatment Options

+

Evidence Profile

Patient Case • Inclusion / exclusion criteria

• Comorbidities

• Contraindications

• MSK treatment preferences

• Drug information

• Published literature - studies, reports,

opinions from Textbooks, Journals,

Manuals, etc.

Evidence

Watson for OncologyKey Case

Attributes

Candidate Treatment Options

Supporting

Evidence

Use key attributes to find candidate

treatment options as determined by

consulting NCCN Guidelines and MSK

expertise

2

Search the corpus for supporting

evidence for each option

3Guidelines

Extract key attributes from the

patient’s case

1

Use Watson’s scoring algorithms

to prioritize treatment options

4

9IBM Confidential

10IBM Confidential

Tak

Peter Mortensen, Watson Health Executive Nordics

[email protected]