Top Banner
Thyroid gland 1. Recognize and understand the coverings of the thyroid gland and their clinical importance. 2. Recognize and understand the main parts of the thyroid gland and their locations, relations and connections. 3. Comprehend the blood supply of the thyroid gland, their relations with recurrent and external laryngeal nerves. 4. Understand the embryological origins of the pituitary gland and its associated malformations. 5. Grasp the clinical correlations of the midline structures of neck related to the thyroid gland and differentiate between them and the those on the lateral side of the neck. 6. Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under light. - Attention please this is one of the most important glands in the human body as u may examine lot’s of patients complaining of having issues with it. So focus on what we are going through here. 4/29/2020 Dr.Shatarat
26

Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

Sep 25, 2020

Download

Documents

dariahiddleston
Welcome message from author
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
Page 1: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

Thyroid gland

1. Recognize and understand the coverings of the thyroid gland and their clinical

importance.

2. Recognize and understand the main parts of the thyroid gland and their locations,

relations and connections.

3. Comprehend the blood supply of the thyroid gland, their relations with recurrent and

external laryngeal nerves.

4. Understand the embryological origins of the pituitary gland and its associated

malformations.

5. Grasp the clinical correlations of the midline structures of neck related to the thyroid

gland and differentiate between them and the those on the lateral side of the neck.

6. Recognize and understand imaging of the thyroid gland.

7. Grasp the histological structure of the thyroid gland and its cells under light.

- Attention please this is one of the most important glands in the human body as u may

examine lot’s of patients complaining of having issues with it.

So focus on what we are going through here.

4/29/2020 Dr.Shatarat

Page 2: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

4/29/2020 Dr.Shatarat

Gross anatomy

Page 3: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

Transverse sections through the neck at the

level of the second sixth cervical vertebrae

It is a midline structure

placed anteriorly

in the lower neck

at the level with

the 5th cervicalto the

1st thoracic vertebrae

4/29/2020 Dr.Shatarat

U need to examine the gland physically & know it’s location. So u should NEVER search for it in the upper part of the neck!!

Page 4: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

It consists of

Right and left lobesconnected

By

A narrow midline isthmus

Dr.Shatarat

Page 5: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

its apex being directed upward as far as

the oblique line on the lamina of the

thyroid cartilage it doesn’t extend

beyond it.

3- Lobs

Each lobe is pear shaped

Apex

base

attached to the side of the cricoid cartilage by a

lateral thyroid ligament

4/29/2020 Dr.Shatarat

its baselies below at the level of the fourth or

5th tracheal ring parallel to them.The rings are easily sensed under the skin. Covered by superficial & deep

fascia.

It should be noted that the normal thyroid gland is

nearly always asymmetric. The right lobe may be even

twice as large as the left lobe.

The right upper pole extends higher up in the neck, and

the lower pole extends lower sometimes, & this should

be taken in consideration as normal variation exists.. So

if u noticed a similar case don’t rush assuming a mass it

could be normal.

Note

The posteromedial aspects of the lobes are

When u remove these muscles which lies next to the apex u’llfind the cricoid cartilage.

Page 6: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

4- THE ISTHMUS

is often present, and it projects

upward from the isthmus

5- Pyramidal lobe

The isthmus extends

upwards &

downwards across

the midline in front

of

the 2ed, 3ed , and 4th

tracheal rings

& it’s variable in size.

A fibrous or fibromuscular band, the levator of the thyroid gland, musculus levator glandulaethyroideae, sometimes descends from the body of the hyoid to the isthmus or pyramidal lobe

if present.

Note

persists in at least 15% of

the population

4/29/2020 Dr.Shatarat

Page 7: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

True capsule

False capsule

6- Coverings and fascia of the thyroid gland

The thyroid gland is surrounded by a

shiny capsule.

4/29/2020 Dr.Shatarat

Page 8: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

A-True capsule, a thin fibrous

capsule,

U can see it after removing the

muscles around the gland. This

fascia is formed by condensation of

the stroma of the gland.

It fixes the gland by being

attached by means of dense

connective tissue to the cricoid

cartilage (part of the larynx) and

superior tracheal rings (part of the

trachea).

The True capsule of thyroid capsule is

much denser in front than behind and the

enlarging gland therefore tends

to push backwards, burying itself round the

sides and even the back of the

Clinical note

DyspneaDysphagia

4/2t9r/2a02c0 hea and esophagus.

Dr.Shatarat

There’s nothing In front of the gland except of the strap muscles, fascia & skin(no bone) thus it enlarges anteriorly in late stages; however in the beginning it enlarges posteriorly.

A good ENT doc. Should have a consideration to investigate the thyroid

gland when a patient comes complaining of respiratory or

odynophagia problems because some cases can be asymptomatic regarding the thyroid & a patient won’t think of

visiting an endocrinologist but he would mostly complain :One or

both of them.

Page 9: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

B- False capsuleit is a loose sheath formed by the visceral

portion of the pretracheal layer of deep

cervical fascia external to the true

capsule. The peritracheal fascia separates

the gland from other organs & fixes it in

position.

The false capsule thickens between the

cricoid cartilage and thyroid gland to

form the

ligament of Berry(The suspensory ligament of the thyroid)

gland

(attaches the thyroid gland to trachea)

4/29/2020 Dr.Shatarat

Please get attention here: the true capsule exist in every organ & has to deal with the organ it self, which makes it irresponsible nether of the attachments nor of separation of the organ to near by structures USUALLY.

Page 10: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

The false capsule of the thyroid

gland also

attaches the gland to

the larynx and even to the hyoid

bone

This explains why the thyroid gland

follows the movements of the

larynx in swallowing moving up &

down .

This information is important because any pathologic neck

swelling that is part of the

thyroid gland will move upward when the patient isasked to swallow

It is clear that the false

capsule is attached to

Both the larynx and

trachea

Clinical note

4/29/2020 Dr.Shatarat

Page 11: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

a large goitre will extend downwards into the

superior

mediastinum

(‘Plunging Goitre’)

The pretracheal layer of deep cervical fascia is attached to hyoid bone

Retrosternal Goiter

The attachment of the sternothyroid muscles to the thyroid

cartilage effectively binds down the thyroid gland to the larynx

This limits upward expansion of the gland

if any pathological condition induced it’s

enlargement. So it wouldn’t extend beyond

this area.

However, downward expansion has no limitation

causing Retrosternal Goiter behind the

manubrium & the sternum.

And

4/29/2020 Dr.Shatarat

Or

Page 12: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

7- Relations of the Lobes

C-The

sternothyroi

d

B-The

sternohyoid

D-The anterior

border of the

sternocleidomastoid

A-The

superior belly

of the

omohyoid

4/29/2020 Dr.Shatarat

If u were a surgeon who wants to remove the thyroid gland u have to be extremely careful dealing with the strap muscles that surrounds it, as well as the four parathyroid glands.

Page 13: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

The anastomosis between

the superior and inferior thyroid arteries.

Posterior view

4/29/2020 Dr.Shatarat

Page 14: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

Posterolaterally:

The carotid sheath with the

common carotid artery, the

internal jugular vein, and the

vagus nerve

The larynx, the trachea, the pharynx,

and the esophagus. Associated with

these structures are the cricothyroid

muscle and its nerve supply, the

external laryngeal nerve. In the

groove between the esophagus and

the trachea is

the recurrent

laryngeal nerve

4/29/2020 Dr.Shatarat

Medially:

Page 15: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

4/29/2020 Dr.Shatarat

Page 16: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

A-The superior thyroid artery

B-The inferior thyroid artery

C- Sometimes the thyroidea ima.

A-The superior thyroid artery, a branch of

the external carotid artery, descends to the

upper pole of each lobe, accompanied by

The External Laryngeal Nerve

4/29/2020 Dr.Shatarat

Page 17: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

The superior thyroid artery on each side is related

to the external laryngeal nerve, which supplies the

cricothyroid muscle.

Damage to the

external

laryngeal

nerve

results in an

inability to

tense the

vocal folds

and in

hoarseness

Thus, The Superior Thyroid Artery during surgery on the thyroid ,

is ligated near the gland to avoid injury to4/29/2020

the external larynDg

r.She

aa

tarlatnerve

Page 18: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

a branch of the thyrocervical trunk,

ascends behind the gland to the level of

the cricoid cartilage.

It then turns medially and downward to

reach the posterior border of the gland.

The recurrent laryngeal

nervecrosses either in front of or behind the artery,

or it may pass between its branches.

B-The inferior thyroid artery

4/29/2020 Dr.Shatarat

Page 19: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

The terminal branches of the

inferior

thyroid artery

on each side are related to the

RECURRENT LARYNGEAL

NERVE.

4/29/2020 Dr.Shatarat

Page 20: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

Thus, THE INFERIOR THYROID ARTERYduring

surgery on the thyroid ,

is ligated away from the gland to avoid injuryto

the recurrent laryngeal nerve

4/29/2020 Dr.Shatarat

Page 21: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

C-The thyroidea ima, In

approximately 10% of people, a

thyroid ima artery

ascends on the anterior surface of

the trachea, which it supplies,

and continues to the isthmus of

the thyroid gland.

s

arises from the brachiocephalic trunk,

or the arch of the aorta,

from the right common carotid

ubclavian, or internal thoracic arteriesVari

ab

le

Clinical note

The possible presence of this artery

must be considered when performing

procedures in the midline of the neck

inferior to the isthmus because it is a 4p

/2o

9t/e20n

2t0ialsource of bleeding

Dr.Shatarat

Page 22: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

4/29/2020 Dr.Shatarat

Lesions of the Laryngeal Nerves

The muscles of the larynx are innervated by

the recurrent laryngeal nerves, with the

exception of the cricothyroid muscle, which is

supplied by the external laryngeal nerve. Both

these nerves are vulnerable during operations

on the thyroid gland because of the close

relationship between them and the arteries

of the gland.

To be discussed next year

Page 23: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

9-The veins from the thyroid gland

C-The inferior thyroid vein

The inferior thyroid veins of the two

sides anastomose with one another as

they descend in front of the trachea.

They drain into the left brachiocephalic

vein in the thorax

A-Superior thyroid vein

which drains into the internal jugular vein;

B-The middle thyroid vein

which drains into the internal jugular vein;

4/29/2020 Dr.Shatarat

Page 24: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

10-The lymphatic vessels of the thyroid gland

communicate with a capsular network of

lymphatic vessels

From this network, the vessels pass

initially to prelaryngeal, pretracheal,

and paratracheal lymph nodes, which

drain in turn to the superior and

inferior deep cervical nodes

Inferior to the thyroid gland, the

lymphatic vessels pass directly to the

inferior deep cervical lymph nodes

4/29/2020 Dr.Shatarat

Page 25: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

The uppermost, just above the

thyroid

isthmus, in front of the cricoid

cartilage, and medial to

a pyramidal lobe, if present, is a

constant node group

of one to five nodes, which has

been termed

The Delphian node

enlargement of which is

indicative of metastasis

from thyroid or

laryngeal carcinoma.

4/29/2020 Dr.Shatarat

Page 26: Thyroid gland - doctor2018.jumedicine.com€¦ · Recognize and understand imaging of the thyroid gland. 7. Grasp the histological structure of the thyroid gland and its cells under

4/29/2020 Dr.Shatarat

Edited by: Sarah Qudah.