Syllabus CBE Sem 3-8

8/14/2019 Syllabus CBE Sem 3-8

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DEPARTMENT OF

CHEMICAL AND

BIO ENGINEERING

VISION

To build a rich intellectual potential

embedded with inter-disciplinaryknowledge, human values and professional

ethics among the youth, aspirant of

becoming engineers and technologists, so

that they contribute to society and create a

niche for a successful career.

MISSION

To become a leading and unique institution ofhigher learning, offering state-of-the-art

education, research and training in engineering

and technology to students who are able and

eager to become change agents for the

industrial and economic progress of the nation.

To nurture and sustain an academic ambience

conducive to the development and growth

committed professionals for sustainable

development of the nation and to accomplish its

integration into the global economy.

QUALITY POLICY

Develop technical human resource of

excellence suitable for global

requirements.

Ensure good quality academic and

industrial research programmes in

different areas of engineering andtechnology.

Generate industry-institute synergy

for shaping technical education to

meet the requirement of industry.


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PREFACE

With upgradation of Regional Engineering College Jalandhar into National Institute of TechnologyJalandhar (Deemed University), the academic programmes are to be regulated in accordance with thestipulations made in National Institute of Technology rules, 2002. Accordingly the institute requires torestructure academic programmes around the credit system in which Mark System of evaluation is

replaced by Letter Grade System and Year wise passing makes way for course wise passing.

We have tried our best to prepare a Model Curriculum and syllabi for four year under graduateprogramme in Chemical and Bio Engineering. The exercise was handicapped with the followingdifficulties:

i) It is interdisciplinary in character involving considerable inputs from other disciplines.ii) It depends on advances in science, technology and materialsiii) Its differential status at the National and International level

It is really challenging to evolve a common programme for this discipline that meets the need ofnational and international industries and research establishments. However, with the rich experienceof successful experimentation with above idea for over forty years, the task of development of a model

curriculum could be possible.

The suggested curriculum is based on philosophy presented by the Dean (Academic Programmes)during 5th Senate meeting of the institute held on January 14, 2005. it possesses the followingfeatures:

i) The suggested curriculum is in conformity with IIT/AICTE norms with emphasis on analysisand design of industrial processes required to work in control environment.

ii) The graduates turned out have to be acceptable by national and international industry andacademic / research establishments.

iii) The programme has to be forward looking in context of the rapid changing scenario ofscience and technology which provides a proper balance in teaching of basic sciences, socialsciences and management, engineering sciences and technical arts, technologies and their

applications.iv) Core subjects have been selected to cover all those, which are essential in training of CB

graduates.v) The curriculum presents flexibility so that new programmes started with reasonable sources

can be managed with a scope of further updating as the resource position improves.

The above features have been achieved by offering a number of electives courses both departmentaland open in nature.

I take this opportunity to express my deep appreciation to members of the Senate for their valuablesuggestions and critical comments in finalizing the curriculum and Professor Pramod S Mehta, Ex-Director, NIT Jalandhar for his initiative and direction. It is hoped that the curriculum complied in formof the booklet will be of immense help to the students and the faculty in smooth running the under

graduate programme in Chemical and Bio Engineering. I thank all the members of curriculumcommittee for their help and cooperation rendered in bringing out this booklet in time.

(M.K. JHA)Dean, Students and AlumniProfessor and HeadDepartment of Chemical and Bio EngineeringDr B R Ambedkar National Institute of TechnologyJalandhar (Punjab)-144011

Place: Jalandhar

Date: 31.5.2005


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CURRICULUM

UNDERGRADUATE PROGRAMME(B. TECH)

Chemical and Bio Engineering

INDEX

S NO CONTENTS PAGE NOS.

1 Philosophy on Development of UG Curriculum 1-2

2 Course Structure (1st to 8th Semester) with details of Credits 3

3 The Overall Credit Structure 4

4 Course Descriptions

Courses offered by CB Department 5-34

Courses offered by other departments 35- 45


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Dr B R AMBEDKAR NATIONAL INSTITUTE OF TECHNOLOGY, JALANDHAR

PHILOSOPHY ON DEVELOPMENT OF UNDER GRADUATE (UG) CURRICULUM ATDr B R AMBEDKAR NATIONAL INSTITUTE OF TECHNOLOGY, JALANDHAR

1. BACKGROUND

With upgradation of Dr B R Ambedkar REC Jalandhar to Dr B R Ambedkar NITJalandhar (Deemed University) education being imparted at the Institute requires to beorganized around credit-based semester system.

There has been a sea-change in objectives, approaches and teaching technology inengineering education during the last couple of years.

This calls for restructuring of existing academic programme

2. OBJECTIVES OF UG-TECHNICAL EDUCATION

to prepare students for the Technical and analytical skills enabling them to have potentialemployment in industry, education, research and management.

to equip the students with an adequate background of Basic Science, EngineeringScience and Arts, Humanities, Social Sciences and Management to enable them to playan effective role of an engineer for benefits of society.

3. SALIENT FEATURES OF CURRICULUM

To realize the above objectives of UG-programmes, curriculum frame work should exhibit the following salient

features:

Undergraduate-curriculum should be a broad based

Science based engineering education, which enables students to use basic sciences intoengineering practice/programmes

Should involve continuous evaluation to avoid rote learning and semester endexaminations

Curriculum should allow varying weightages to various categories of courses

Should provide flexibilities in choice of Electives Departmental and Non-departmental

A dynamic regulatory and reviewing process is required to ensure that the proposedcurriculum is current.

4. NECESSARY RECOMMENDATIONS

To ensure the above enumerated salient features of UG-programmes, the following major recommendations

were given by Curriculum Core Committee, which were taken as Requirements and guidelines for the B.Tech

programme at NIT Jalandhar:

R1 The duration of UG-degree course should be limited to 4 years / 8-semesters each of aminimum of 70-working days. 16-weeks will ordinarily be the duration ofinstructions/semester.

R2 The first two semesters should be common to all branches of engineering

R3 Teaching should be reckoned in terms of contact hours. Norms chosen for contact hoursand credit correspondence are the same as being observed in IITs i.e. 100% weightageto L and T & 50% weightage to Practical / Lab contact hours.

R4 Number of credits required to qualify for = 200B.Tech degree should not exceed

R5 Max / Min number of credits required in any semester = 30/15

R6 Total credits divided between various components of = 3:2


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L,T and P-credits have the ratio : L : (T+P)

R7 Max / Min contact hours for instructions / week = 34/24

R8 Max number of years allowed for completing degree- = 06requirements

R9 Distribution of credits among various categories of courses

HSS and Management : 12 Credits Basic Science (BS) : 32 Credits Engineering Sciences & Arts : 36 Credits Professional / Departmental : 106* Credits Electives (including Emerging Technology) : 14 Credits

* Departmental credits also include 10-credits for Project and 8-credits for

Industrial Training.

R10 Provision for Non-credit courses (Audit courses) should be made in the last 2-years ofUG-programmes.

R11 The Major Project should be spread over the last 2-semesters Phase-I and Phase-IIwith appropriate distribution of credits (8-12 credits).

R12 Basic Courses should be planned to be taught in large class environment. Tutorial /practical Group size should not exceed 20.

R13 For Laboratory practice a bank of experiments should be prepared with at least 100%more than those performed during a semester. Some experiments especially in highersemesters shouldl be open-ended be performed without the help of technician.

R14 A number of Elective courses (5-6 electives) should be offered starting from the 4th

semester to make the curriculum flexible and the core subjects be adjusted accordingly.Numbering scheme for electives should depend on the sequence of semester in whichoffered.

R15 Identification of common courses to more than one coherent departments should bedone for ensuring economic use of faculty and infrastructural facilities in the Institute.

R16 Participation by persons from industry should be encouraged in teaching courses,supervision and evaluation of Industrial Training and Project works.

R17 Students should be required to attend at least 75% of the scheduled L, T and practicalcourses*.

* The percentage of attendance calculated up to last day of instructions will reflect into aCode-number or Letter in the Grade Sheets.

R18 Students must undergo Industrial Training at least for 90-100 days. In addition, theymust participate in NSS, NCC, NSO, Literacy Mission etc. as mandatory requirement toqualify for B.Tech degree.

NOTE:

The above major recommendations have served as guidelines for all departments offeringUG-programmes for award of B.Tech Degree in NIT Jalandhar. However, marginal variations in abovesuggested distribution of credits may be allowed to suit the requirement of the individual programme.

(Dr R Jha)Dean, Academic ProgrammesJanuary 14, 2005


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Course Structure B. Tech in Chemical and Bio Engineering

Sem

LectureCourses

L T P

WeeklyContact

Hrs

I MA-101Math-I(3 1 0) 4

PH-101Physics(3 1 0) 4

PH-103Physics Lab(0 0 2) 1

IC-101Electrical Sci(3 1 0) 4

IC-103Electrical SciLab(0 0 2) 1

IE-101Mfg. Processes(2 0 0) 2

IE-103Mfg. ProcessesLab(0 0 4) 2

HM-101Int. to Mgt. &Comm.(3 0 2) 4

ME-101ThermalScience(3 1 0) 4

CS-101Comp.Software Theory & Prc.(1 0 2) 2

07 18 04

12 34 28

II MA-102Math-II(3 1 0) 4

CH-101Chemistry(3 1 0) 4

CH-103Chemistry Lab(0 0 2) 1

EC-101BasicElectronics(3 1 0) 4

EC-103BasicElectronics Lab(0 0 2) 1

MC-101Mechanics ofSolids & Fluids(3 0 0) 3

MC-103Mech. of Solids& Fluids Lab((0 0 2) 1

HM-102Engg Eco &Fin. Mgmt.(3 1 0) 4

ME-102EngineeringGraphics(2 0 0) 2

ME-104EngineeringGraphics Lab(0 0 4) 2

06 17 04

10 31 26

III MA-200NumericalMethods(3 1 0) 4

CB-201

Microbiology

(3 1 0) 4

CB-203

MechanicalOperation

(3 1 0) 4

CB-205

Chem. ProcessCalculation

(3 2 0) 5

CB-207

ChemicalTechnology

(3 1 0) 4

CB-209

EnergyEngineering

(3 1 0) 4

CB-221

MicrobiologyLab.

(0 0 2) 1

CB-223

MechanicalOperations Lab.

(0 0 2) 1

CB-227

Chemical Tech.Lab

(0 0 2)1

06 18 07

06 31 28

IV MA-202OptimizationTechniques(3 0 2) 5

PH-204MaterialScience & Engg(3 1 0) 4

CB-202Biochemistry

(3 0 0) 3

CB-222

BiochemistryLab(0 0 3) 2

CB-204Heat Transfer

(3 1 0) 4

CB-206Chemical Engg.Thermodyna.

(3 1 0) 4

CB-208Chem. ReactionEngg-I(3 1 0) 4

PH-224

Material Sc. &Engg. Lab(0 0 2) 1

CB-224Energy Engg.Lab.(0 0 3) 2

06 18 04

10 32 28

3

V CB-301Mass Transfer I

(3 1 0) 4

CB-303

Chem. ReactionEngg. II

(3 1 0) 4

CB-305PetroleumRefining Engg.(3 1 0) 4

CB-307BioprocessEngg.

(3 1 0) 4

CB-309Process PlantDesign I

(1 0 3) 3

CB-321

Heat TransferLab.

(0 0 2) 1

CB-327

Bio processEngg. Lab.

(0 0 2) 1

CB-3XXDE-I(3 0 0) 3

06 16 04

07 27 24

VI CB-302Mass Transfer II

(3 1 0) 4

CB-304

Process Eco. &Mngt.(3 0 0) 3

CB-306Process PlantDesign II

(1 0 2) 2

CB-3XXDE-II(3 0 0) 3

CB-322

Mass TransferLab.

(0 0 2) 1

OC-3XXOE-I(3 0 0) 3

05 13 01

04 18 16

Summer CB-300 Industrial Practical Training (0 0 16) 8 08

VII CB-401ChemicalProcess Control(3 1 0) 4

CB-403MolecularBiology &Genetic Engg.(3 0 0) 3

CB-405IndustrialInstrumentation(2 0 0) 2

CB-423ProcessModeling &Sim. Lab(0 0 4) 2

CB-400Project (Ph-I)(0 0 4) 2

CB-427

Colloquium

(0 0 2) 1

CB-4XXDE-III(3 0 0) 3

OC-4XXOE-II(3 0 0) 3

05 14 01 10 25 20

VIII CB-402IndustrialBiotechnology(3 0 0) 3

CB-404EnvironmentalEngg. & Saf.

(3 1 0) 4

CB-422Chem. ProcessCont. & Rxn.Engg. Lab.

(0 0 2) 1

CB-424

EnvironmentalEngg. Lab.

(0 0 2) 1

CB-400Project (Ph-II)(0 0 16) 8

CB-4XXDE-IV(3 0 0) 3

03 9 01 20 30 20

Total 198

DE : 4 @ 3C = 12 C HM : 2 @ 4 = 8C from 2-courses

OE : 2 @ 3 = 6 C DC : 113, BS : 31, EAS : 28


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Undergraduate Core (UC) Undergraduate Elective(UE)

Category Credits Category Credits

HSS&M 08 DE 12

BS 31 OE 06

EAS 28

DC 113TOTAL 180 TOTAL 18

Total Credits = 198

Humanities, Social Sciences and Management (HSS&M)

HM-101 Introduction to Management andCommunication

3-0-0 3

HM-102 Engineering Economics andFinancial Management

3-1-0 4

HM-103 Communication Laboratory 0-0-2 1TOTAL HSS&M 6-1-2 8

Basic Sciences (BS)

MA-101 Mathematics-I 3-1-0 4MA-102 Mathematics-II 3-1-0 4MA-200 Numerical Methods 3-1-0 4

MA-202 Optimization Techniques 3-0-2 4

PH-101 Physics 3-1-0 4PH-103 Physics Laboratory 0-0-2 1PH-204 Material Science & Engineering 3-1-0 4PH-224 Material Science & Engineering

Laboratory0-0-2 1

CH-101 Chemistry 3-1-0 4CH-103 Chemistry Laboratory 0-0-2 1

TOTAL BS 21-6-8 31

Engineering Arts and Sciences (EAS)

IC-101 Electrical Science 3-1-0 4IC-103 Electrical Science Laboratory 0-0-2 1EC-101 Basic Electronics 3-1-0 4EC-103 Basic Electronics Laboratory 0-0-2 1CS-101 Computer Software Theory

and Practice1-0-2 2

IE-101 Manufacturing Processes 2-0-0 2

IE-103 Manufacturing ProcessesLaboratory

0-0-4 2

ME-101 Thermal Science 3-1-0 4ME-102 Engineering Graphics 2-0-0 2ME-104 Engineering Graphics

Laboratory0-0-4 2

MC-101 Mechanics of Solids and Fluids 3-0-0 3MC-103 Mechanics of Solids and Fluids

Laboratory0-0-2 1

TOTAL EAS 17-3-16 28

Departmental Core (DC)

CB-201 Microbiology 3-1-0 4CB-202 Biochemistry 3-0-0 3CB-203 Mechanical Operations 3-1-0 4CB-204 Heat Transfer 3-1-0 4

CB-205 Chemical ProcessCalculations 3-2-0 5

CB-206 Chemical EngineeringThermodynamics

3-1-0 4

CB-207 Chemical Technology 3-1-0 4CB-208 Chemical Reaction

Engineering I3-1-0 4

CB-209 Energy Engineering 3-1-0 4CB-221 Microbiology Laboratory 0-0-2 1CB-222 Bio Chemistry Laboratory 0-0-3 2CB-223 Mechanical Operations

Laboratory0-0-2 1

CB-224 Energy EngineeringLaboratory

0-0-3 2

CB-227 Chemical TechnologyLaboratory

0-0-2 1

CB-300 Industrial Practical Training 0-0-16 8CB-301 Mass Transfer - I 3-1-0 4

IC-302 Advanced Process Control 3-1-0 4IC-303 Transducers and Signal 3-1-0 4CB-302 Mass Transfer II 3-1-0 4CB-303 Chemical Reaction

Engineering II3-1-0 4

CB-304 Process Economics &Management

3-0-0 3

CB-305 Petroleum RefiningEngineering

3-1-0 4

CB-306 Process Plant Design II 1-0-2 2CB-307 Bioprocess Engineering 3-1-0 4CB-309 Process Plant Design I 1-0-3 3CB-321 Heat Transfer Laboratory 0-0-2 1CB-322 Mass Transfer Laboratory 0-0-2 1CB-327 Bioprocess Engineering

Laboratory0-0-2 1

CB-400 Project (Phase-I & II) 0-0-20 10CB-401 Chemical Process Control 3-1-0 4CB-402 Industrial Biotechnology 3-0-0 3CB-403 Molecular Biology & Genetic

Engineering3-0-0 3

CB-404 Environmental Engineeringand Safety

3-1-0 4

CB-405 Industrial Instrumentation 2-0-0 2CB-422 Chemical Process Control &

Reaction Engineering

Laboratory

0-0-2 1

CB-423 Process Modeling andSimulation Laboratory

0-0-4 2

CB-424 Environmental EngineeringLaboratory

0-0-2 1

CB-427 Colloquium 0-0-2 1TOTAL DC 61-16-69 113

Department Electives (DE)

Open Electives (OE)

CB-310 Bioinformatics 3-0-0 3

CB-311 Enzyme Technology 3-0-0 3CB-312 Protein Engineering 3-0-0 3CB-313 Bio Pharmaceuticals 3-0-0 3CB-314 Petrochemical Technology 3-0-0 3CB-315 Transport Phenomena 3-0-0 3CB-410 Immunology 3-0-0 3

CB-411 Food Biotechnology 3-0-0 3CB-412 Cell and Tissue Culture 3-0-0 3CB-413 Down Stream Processing 3-0-0 3CB-414 Polymer Technology 3-0-0 3CB-415 Plant Utilities 3-0-0 3CB-416 Natural Gas Engineering 3-0-0 3CB-417 Petroleum Recovery

Technology3-0-0 3

Programme Code: CBBachelor of Technology in Chemical and Bio Engineering

Department of Chemical and Bio EngineeringThe overall credit structure


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COURSE DESCRIPTIONS

(Courses Offered by CB Department)

OC/CB-332 Energy Technology 3-0-0 3OC/CB-431 Basic Biotechnology 3-0-0 3


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TEACHING SCHEME

FIRST SEMESTER, GROUP A/SECOND SEMESTER GEOUP B

S. NO. COURSE NO. COURSE TITLE PERIODSL T P/D

CREDITS

1. CH 101 Chemistry 3 1 0 4

2. EC-101 Basic Electronics 3 1 0 4

3. HM-101 Introduction to Management 3 0 0 3

4. HM-102 Engineering Economics andFinancial Management

3 1 0 4

5. MA-101/MA-102 Mathematics-I/Mathematics-II 3 1 0 4

6. MC-101 Mechanics of Solids & Fluids 3 0 0 3

7. ME-102 Engineering Graphics 2 0 0 2

8. CH-103 Chemistry 0 0 2 1

9. EC-103 Basic Electronics Laboratory 0 0 2 1

10. MC-103 Mechanics of Solids & FluidsLaboratory

0 0 2 1

11. ME-103 Engineering GraphicsLaboratory

0 0 4 2

TOTAL 20 4 10 29

Drawing practice

Contact Hours = 34

FIRST SEMESTER, GROUP B/SECOND SEMESTER GEOUP A

S. NO. COURSE NO. COURSE TITLE PERIODS

L T P/D

CREDITS

1. HM-101 Introduction to Management andCommunication

3 1 0 4

2. IC-101 Electrical Science 3 1 0 4

3. IE-101 Manufacturing Processes 2 0 0 2

4. MA-101/MA-102 Mathematics-I/Mathematics-II 3 1 0 4

5. ME-101 Thermal Science 3 1 0 4

6. PH-101 Physics 3 1 0 4

7. CS-103 Computer Software Theoryand Practical

1 0 2 2

8. HM-103 Communication Laboratory 0 0 2 1

9. IC-103 Electrical Science Laboratory 0 0 2 1

10. IE-103 Manufacturing Process 16Laboratory

0 0 4 2

11. PH-103 Physics Laboratory 0 0 2 1

TOTAL 18 5 12 29

Contact Hours = 35


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TEACHING SCHEME OF THIRD SEMESTER

SNo

CourseNo

Course Title Periods

L T P

Contact Hours

Credits

1. MA-200 Numerical Methods 3 1 0 4 4

2. CB-201 Microbiology 3 1 0 4 4

3. CB-203 Mechanical Operations 3 1 0 4 4

4. CB-205 Chemical Process Calculations 3 2 0 5 5

5. CB-207 Chemical Technology 3 1 0 4 4

6. CB-209 Energy Engineering 3 1 0 4 4

7. CB-221 Microbiology Laboratory 0 0 2 2 1

8. CB-223 Mechanical Operations Laboratory 0 0 2 2 1

9. CB-227 Chemical Technology Laboratory 0 0 2 2 1

Total 18 7 6 31 28

Fourth Semester

SNo

CourseNo


L T P

Contact Hours

Credits

1. PH 204 Material Science and Engineering 3 1 0 4 4

2. CB-202Biochemistry

3 0 0 3 3

3.MA 202 Optimization Techniques

3 0 2 5 4

4. CB-204Heat Transfer

3 1 0 4 4

5. CB-206 Chemical EngineeringThermodynamics

3 1 0 4 4

6. CB-208 Chemical Reaction Engineering I 3 1 0 4 4

7. PH 224 Material Science and EngineeringLaboratory

0 0 2 2 1

8. CB-222Biochemistry Laboratory

0 0 3 3 2

9. CB-224 Energy Engineering Laboratory 0 0 3 3 2

Total 18 4 10 32 28


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Fifth Semester

SNo

CourseNo


L T P

Contact Hours

Credits

1. CB 301 Mass Transfer I 3 1 0 4 4

2 CB 303 Chemical Reaction Engineering -II

3 1 0 4 4

3 CB 305 Petroleum Refining Engineering 3 1 0 4 4

4 CB 307 Bioprocess Engineering 3 1 0 4 4

5 CB 309 Process Plant Design I 1 0 3 4 3

6. CB 3XX Elective I 3 0 0 3 3

7 CB 321 Heat Transfer Laboratory 0 0 2 2 1

8 CB-327 Bioprocess Engineering Laboratory 0 0 2 2 1

Total 16 4 7 27 24

Sixth Semester

SNo

CourseNo


L T P

Contact Hours

Credits

1 CB 302 Mass Transfer II 3 1 0 4 4

2 CB 304 Process Economics andManagement

3 0 0 3 3

3 CB 306 Process Plant Design II 1 0 2 3 2

4 CB 3XX Elective II 3 0 0 3 3

5 OC 3XX Open Elective I 3 0 0 3 3

6 CB 322 Mass Transfer Laboratory 0 0 2 2 1

7. CB 300 Industrial Practical Training 0 0 0 0 8

Total 13 1 4 18 24


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Seventh Semester

SNo

CourseNo


L T P

Contact Hours

Credits

1 CB 401 Chemical Process Control 3 1 0 4 4

2 CB 403 Molecular Biology and GeneticEngineering

3 0 0 3 3

3 CB 405 Industrial Instrumentation 2 0 0 2 2

4 CB 4XX Elective III 3 0 0 3 3

5. OC 4XX Open Elective II 3 0 0 3 3

6 CB 423 Process Modeling and SimulationLaboratory

0 0 4 4 2

7. CB 400 Project ( Phase I) 0 0 4 4 2

8. CB 427 Colloquium 0 0 2 2 1

Total 14 1 10 25 20

Eighth Semester

SNo

CourseNo


L T P

Contact Hours

Credits

1 CB 402 Industrial Biotechnology 3 0 0 3 3

2 CB 404 Environmental Engineering andSafety

3 1 0 4 4

3 CB 4XX Elective IV 3 0 0 3 3

4. CB 422 Chemical Process Control andReaction Engineering Laboratory 0 0 2 2 1

5. CB 424 Environmental EngineeringLaboratory

0 0 2 2 1

6. CB 400 Project ( Phase II) 0 0 16 16 8

Total 9 1 24 29 20


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List of Electives

Elective I

S.No Course Title L T P C

1 CB 311 Enzyme Technology 3 0 0 3

2 CB 313 Bio Pharmaceuticals 3 0 0 3

3 CB 315 Transport Phenomena 3 0 0 3

Elective II


1 CB 310 Bioinformatics 3 0 0 3

2 CB 312 Protein Engineering 3 0 0 3

3 CB 314 PetrochemicalTechnology

3 0 0 3

Elective III


1 CB 411 Food Biotechnology 3 0 0 3

2 CB 413 Down StreamProcessing

3 0 0 3

3 CB 415 Plant Utilities 3 0 0 3

4 CB 417 Petroleum RecoveryTechnology

3 0 0 3

Elective IV


1 CB 410 Immunology 3 0 0 3

2 CB 412 Cell and Tissue Culture 3 0 0 3

3 CB 414 Polymer Technology 3 0 0 3

4 CB 416 Natural GasEngineering

3 0 0 3

Open Elective I


1 OC/CB 332 Energy Technology 3 0 0 3

Open Elective II


1 OC/CB 431 Basic Biotechnology 3 0 0 3


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DEPARTMENT OF CHEMICAL AND BIO ENGINEERING

CB- 201 Microbiology [ 3 1 0 4 ]

Scope and History of Microbiology: Scope and History of Microbiology, Classification,Characterization, Identification and Nomenclature of Microorganisms, Microscopy,Morphological, Structural and Biochemical characteristics of prokaryotes and eukaryotes(bacteria , yeast, mold, algae, protozoa, actinomycetes)Cultivation of Microorganisms: Microbiological media, physical conditions required forgrowth.Reproduction and Growth of Microorganism: Modes of cell division , growth curve ofmicrobes, Quantitative measurement of growth.Methods in Microbiology: Chemical, Physical and Biological methods of selection ofmicroorganisms , Methods of isolating pure cultures , Maintenance and preservation of purecultures , microbial mutation .Microbial Metabolism: Metabolic pathways and Bioenergetics, Aerobic and Anaerobic

growth, Transport of nutrients across cell membranesPhysical and Chemical Control of Microorganism: Major groups of antimicrobial agents ,Mode of action and practical applicationsEnergy Transduction Mechanisms in Microbial Cell : Aerobic and anaerobic respiration,Microbial photosynthesis, Transduction, Transformation, ConjugationMicrobial Interaction :- Roles of microbes in Nitrogen, Carbon and Sulphur cycleApplication of Microorganism in various Field : - Agriculture, food, environment ,medicine, public health and industry.Viruses: Classification, morphology and composition, DNA and RNAbacteriophages,Lysogeny and lytic cycle

Books Recommended

1. Pelczar M J, Chan E C S and Krieg N R Microbiology, Mc Graw Hill, New York(1995)

2. Salle A J, Fundamental Principles of Bacteriology, Tata McGraw Hill, New Delhi(1984)

3. Stanier R Y, Text in Microbiology McMillan Press London (1995)4. Davis B D, Microbiology, Harper and Row Publications, Hageston (1980)5. Casida L E, Industrial Microbiology, New Age International Publishers, New Delhi

(2003)

CB-202 Biochemistry [3 0 0 3]

Molecular basis of life,tudy of macro moleculesCarbohydrates: Their structure and biological functions, Monosaccharides disaccharidesand polysaccharides Glycoproteins. Amino Acids and Proteins: Their structure and function,Types of amino acids,Fbrousproteins and globular proteins, Separation of proteinsFats and Lipids: Their structure and biological functions, Types of lipids, triacylglycerol,Waxes, Phospolipids, Sphingolipids, LipoproteinsNucleic acid and Nucleotides : DNA, Structure of chromosomes and genes, Replicationand transcription of DNA, RNA Protein synthesis and its regulation, Genetic recombinationand cloningVitamins and Harmones: Types, Structure and functions

Photosynthesis: Chlorophylls, Kinds and roles of photosystems, Calvin cycle


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Enzymes: Properties and types, Kinetics of enzyme action, Enzyme inhibition,Allostericenzymes, Assay of enzymes, Regulation of enzyme activityBioenergetics and Metabolism: Metabolism, basic concepts and design, Glycolysis citricacid cycle oxidative phosphorylation pentose phospate pathway and gluconeogenesisglycogen and disaccharide metabolism amino acid degradatoon and urea cycleBiological Membranes: Characteristics of biological membranes components ofmembranes types of membranes fluid mosaic model membrane asymmetry

Books Recommended

1. Stryer L, Biochemistry,W.H.Freeman and Company (1995)2. Lehninger, A L Principles of Biochemistry, Butterworth Publishers, New York

(1993)

3. Conn E E and Stumpf P K Outlines of Biochemistry ,John Wiley and Sons, NewYork (1987)

4. Walsh G , Proteins Biochemistry and BiotechnologyJohn Wiley and sons (2003)5. Rastogi, Biochemistry, 2nd Edition, Tata Mc Graw Hill (2003).

CB-203 Mechanical Operations [3 1 04 ]

Size Reduction : Particle size and shape, particle mass, size and shape distributions,measurement and analysis, concept of average diameter ,size reduction , crushing, grindingand law of grindings.Screening : Screening equipment ,capacity and effectiveness of screen, effect of mesh sizeon capacity of screen.Settling : Flow around a single particle, drag force and drag coefficient, settling velocity ofparticles in a fluid, hindered and free settling of particles, thickening gravity separationFiltration : Classification of filters, various types of cake filters ,principle of cake filtration,clarification filters, liquid clarification, centrifugal settling process.Agitation & Mixing: Agitation of liquids, axial flow impellers, radial flow impellers, velocityand power consumption of agitated vessels, blending & mixing.Fluidization : Packed beds, bed porosity, flow though a bed of particles, fluidization &fluidized bed, conditions for fluidization minimum velocity, types of fluidization.Solid Handling : Flow of solid by gravity, transport of solids by screw / belt conveyers,cyclones, bag filters, electrostatic precipitators, particulate collection system.

Books Recommended

1. Smith J C, Mccabe W L and Harriot P H, Unit Operations of Chemical Engineering,

McGraw Hill (2001).2. Bhattacharya B C and Narayanan C M Mechanical Operation for Chemical

Engineers

3. Perrys, Handbook of Chemical Engineering, 7th Ed, McGraw Hill (1997).4. Brown G G Unit Operations 1st ed. , CBS Publisher (2004)5. Richardson and Coulson Chemical Engineering Vol II,5 th ed., Butterworth

Heinemann (2003).

CB-204 Heat Transfer [3 1 0 4]Conduction: Basic law of heat conduction Fouriers law, thermal conductivity, itsdependence on temperature, steady state heat conduction through a composite solid and itselectric analogue, steady state heat conduction through cylinders, spheres and variable areaof solids, different insulating materials and their applications for process equipment and


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pipelines, Fouriers law in three dimensions, lumped capacity method of unsteady stateconduction.Convection: Convection heat transfer and the concept of heat transfer coefficient, individualand overall heat transfer coefficient, heat transfer between fluids separated by plane wall,heat transfer between fluids separated by cylindrical wall (pipes), critical/ optimum insulationthickness, heat transfer through extended surfaces.Forced Convection: Over a flat plate, thermal boundary layer, dimensionless groups anddimensional analysis, Buckingham Pi-theorem, heat transfer correlations- internal andexternal flows, laminar and turbulent flows,Free convection: Heat transfer correlations for free convection, free convection from flatsurfaces, free convection from a cylinder.Heat Transfer with phase change: Boiling phenomena and analysis of boiling curve,correlation for nucleate boiling, critical heat flux, condensation phenomena, filmcondensation on a vertical surface (Nusselt equation, effect of non-condensable gases, dropwise condensation.Radiation: Basic principle of radiation from a surface, blackbody radiation, Plancks law,Weins displacement law, the Stefan Boltzmann law, Kirchoffs law, gray body, radiation

exchange between black bodies & gray bodies.Evaporation: Types of evaporators, single and multiple effect evaporators, capacity andeconomy, boiling point elevation.

Books recommended

1. Geankopolis C J, Transport Processes and Separation Process Principles, PrenticeHall of India, 4th Edition, Eastern Economy Edition (2004)

2. Holman J P, Heat Transfer, McGraw Hill Book Co. (1992).3. Incropera F P and DeWitt D P, Introduction to Heat Transfer, 2nd Ed John Wiley

New York (1996).

4. Kern D Q, Process Heat Transfer, McGraw Hill Book Co. (1997).

5. Coulson J M and Richardson J F, Chemical Engineering Volume 1, PergamonPress (1999).

CB-205 Chemical Process Calculations [3 2 0 5]

Introduction to Chemical Engineering Calculations: Units and dimensions, mole concept,conventions in methods of analysis and measurement, basis, temperature, pressure, thechemical equations and stoichiometry, limiting and excess reactant, conversion and yield.Material Balance: Material balance, program of analysis of material balance problems,solving material balance problems that do not involve chemical reactions, solving materialbalances problems involving chemical reactions, multiple subsystems, recycle, bypass, andpurge calculations.

Gases Vapors, Liquids and Solids: Ideal gas law calculations, real gas relationships,vapor pressure and liquids, saturation, partial saturation and humidity.Energy Balances: Concepts and units, calculation of enthalpy changes, application of thegeneral energy balance without reactions occurring, energy balances that account forchemical reaction, reversible processes and the mechanical energy balances, heats ofsolution and mixing, psychrometric charts and their use.

Books recommended

1. Himmelblau D M, Basic Principles and Calculations in Chemical Engineering,Prentice Hall (1998).

2. Haugen O A, Watson K M and Ragatz R A, Chemical Process Principles (Part-I):

Material and Energy Balances, Asia Publishing House (1995).


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3. Bhatt B I and Vora S M, Industrial Stoiciometry: Tata McGraw Hill Publishing, NewDelhi (1987).

4. Reklaitis G V, Introduction to material and energy balancesWiley, New York (1983)5. Felder R M and Rousseau R W, Elementary principles of Chemical Processes

Wiley, New York 2nd Edition (1986)

CB-206 Chemical Engineering Thermodynamics [3 1 0 4]

Review of First ,Second and Third Law of Thermodynamics : First law ofThermodynamics , Thermodynamics state and state functions , enthalpy, the steady statesteady flow process, equilibrium, phase rule, reversible processes , Second law ofthermodynamics, Heat engines, Entropy, Entropy changes of an ideal gas,Third law of thermodynamics.Volumetric properties of pure fluids :PVT behaviour for an ideal gas, Virial equation ofstate, Applications of Virial equations, Cubic equation of state, Generalized correlations,Acentric factors.Heat Effects : Sensible Heat Effects , Internal Energy of ideal gases, Latent heat of pure

substances , Standard heat of reaction, formation , combustion, Heat of reaction at highertemperature, Heat effects of Industrial reactions.Thermodynamic Properties of fluid: Maxwell relations, Residual properties, Two phasesystem, Thermodynamic diagramEquilibrium and Stability: Criteria of equilibrium, Chemical Potential, Application ofequilibrium criteria, Clausius clapeyon equation.Phase Equilibria: Fugacity ,Determining of fugacity of pure substances, Fugacity inmixture, Ideal solution , Excess properties, Liquid phase properties from VLE data, Activitycoefficients, coefficient equations.Chemical Reaction Equilibria: Reaction ordinate for single & multiple reactions , conditionof equilibrium for a chemical reactions, Standard states and G, Temperature dependence ofthe equilibrium constant , Estimation of equilibrium rate constant , Homogeneous gas phase

reactions, Heterogeneous chemical equilibrium.

Books Recommended

1. Smith J M, Van Ness H C, Abbott M M, Introduction to Chemical EngineeringThermodynamics , McGraw Hill ( TMH Edition), 6th ed (2003).

2. Rao Y V C, Chemical Engineering Thermodynamics, First Edition, UniversitiesPress (India) Ltd., Hyderabad (1997).

3. Kyle B G, Chemical and Process Thermodynamics, Third Edition, Prentice HallPTR, Upper Saddle River, New Jersy (1999).

4. Denbigh K G, Principles of Chemical Equilibrium, Cambridge University Press, 4th

ed. (1981).5. Keeneth S Pitzer, Thermodynamics, McGraw Hill, 3rd ed.

CB- 207 Chemical Technology [3 1 0 4 ]

Soaps & Detergents: Raw materials and Reaction Chemistry, Continuous process formanufacture of fatty acids, soaps and glycerine, Classification of detergents, Builders andadditives, Manufacture of detergents like alkyl benzene sulphonate ,Sodium alkanesulphonate.Cane Sugar: Manufacturing equipments and technology, Cane sugar refining. Polymers :Nomenclature of polymers and their classification, Modes of polymerisation i.e addition,condensation , step growth and chain growth polymerisation , Methods of polymerisation,

Synthetic fibres: Cellulosic fibres, manufacture of Viscose Rayon , Polyamides; Plastics :


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Classification, manufacture of different types of Polyethylene; Rubbers : Natural rubber,different types of synthetic rubbers, manufacture of styrene- butadiene rubberChlor- Alkali Industry: Electrochemistry of brine electrolysis , diaphragm cells, mercury,cells, membrane cells ,Manufacture of caustic soda , chlorine and hydrochloric acid ,Manufacture of Soda AshPortland Cement: Raw materials, types and properties of cement, manufacture of portlandcement.Sulphuric Acid: Raw materials, Contact process of the manufacture of sulphuric acid andoleumFertilizers : Elements required for plant growth, classification of fertilizers,N-P-K Values,Ammonia based fertilizers, Phosphatic fertilizers, Potash fertilizers

Books Recommended

1. Dryden C E, Outlines of Chemical Technology, East West Press Pvt. Ltd., New Delhi,2nd Edition (1973 )

2. Austin G T, Shreves Chemical Process Industries, McGraw Hill Book Company, New

Delhi 5th

Edition (1986 )3. Chemical Engineering Education Development Centre Chemical Technology I, II, III ,

IV , Manual of Chemical Technology, Indian Institute of Technology , Madras.

4. Shukla S D and Pandey G N, A text book of Chemical Technology Vol I, VikasPublishing House Pvt. Ltd., New Delhi

5. Shukla S D and Pandey G N, A text book of Chemical Technology Vol lI, VikasPublishing House Pvt. Ltd., New Delhi

CB-208 Chemical Reaction Engineering - I [3 1 0 4]

Introduction: Kinetics of homogeneous chemical and biochemical reactions, single andmultiple reactions, order & molecularity, rate constant, elementary and non elementaryreactions, temperature dependent term of rate equation,Interpretation of Batch Reactor: Constant volume batch reactor, integral method ofanalysis of data, series and parallel reactions, reversible reactions, Variable volume batchreactor, Differential methods of analysis, Temperature and reactions rate.Introduction to Reactor Design: Ideal batch reactor, mixed flow reactor, plug flow reactor,holding and space time, design for single reactions, size comparison (analytical andgraphical method, plug flow reactors in series & parallel, mixed reactor in series , recyclereactors.Design for Multiple Reactions: Reactions in parallel and series in C.S.T.R, reactions inparallel and series in Plug flow reactor, yield & selectivity.Temperature and Pressure Effect: General design procedure, optimum temperature

progression, adiabatic operation, non adiabatic operation, semi batch reactors.Non Catalytic Fluid Solid Reactions: Selection of model, unreacted core model forspherical particles, diffusion through gas film control, diffusion through ash layer control,chemical reaction control, Design.

Books Recommended

1. Levenspiel O, Chemical Reaction Engineering, 3rd Ed , John Wiley & Sons,Singapore (1999).

2. Fogler H Scott, Elements of Chemical Reaction Engineering, 3rd ed, Prentice HallInc. (1999).

3. Smith J M , Chemical Engineering Kinetics, McGraw Hill , 3rd ed. (1981).

4. Hill, C G, Chemical Engineering Kinetics and Reactor Design, John Wiley (1977).


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5. Coulson J M and Richardson J F, Chemical Engineering Volume 3, PergamonPress (1999).

CB-209 Energy Engineering [3 1 0 4 ]

Solid Fuels : Principle Solid Fuels Coal, origin , composition & classification of coal,properties of coal , terms used in analysis of coal, classification of Indian coals , petrology ofcoalCoal Preparation : Dry and Wet processes, storage of coal. Coal carbonisation :mechanism of carbonisation , high temperature and low temperature carbonizationbriquetting, gasification of coal, Lurgi process, Winkler process , Kopper Totzek process ,liquefaction of solid fuels.Liquid Fuels: Petroleum and related products,origin, occurrence and reserves, nature ofpetroleum crudes, classification and characteristics of petroleum, Refining Unit Process:Cracking, Thermal Cracking ,Catalytic cracking , Hydrocracking, Reforming Thermal andCatalytic Reforming, Alkylation, Polymerization Isomerization, petroleum products :naphtha,motor gasoline, aviation gasoline , kerosene , diesel oil, gas oil , fuel oil , lubricants ,

petroleum waxes,petroleum coke.Gaseous Fuels: Classification, Wobbe Index natural gas, methane from coal mines,producer , water, carbureted water gas , coal, blast furnace , refinery gases , LPG.Combustion: General Principles of combustion, stoichiometry & heat balance calculations,coal burning equipments, stokers, pulverized fuel burners gas and oil burners, fluidized bedcombustion.Alternate Energy Systems: Solar Energy Photovoltaic cells , solar collectors. Nuclearenergy: nuclear reactions, fuel materials, moderators and structural materials, reactors,wind energy, tidal energy, geothermal energy .Furnaces : General classification and description of different types of furnaces.

Books Recommended

1. Brame J S and King J C, Fuels- Solid, Liquid and Gaseous, St. Martin Press2. Sarkar S, Fuels and combustion, Longman publishers India Ltd.., IInd Edition3. Haslam R T and Russel R P, Fuels and their combustion, McGraw Hill4. Gupta O P, Elements of Fuels, Furnaces and Refractories, Khanna Publishers5. Griswold J, Fuels combustion and furnaces, McGraw Hill

CB-221 Microbiology Laboratory [0 0 2 1]

1. To study the microscope.2. Calibration of pH meter.

3. Preparation and sterilization of the medium for bacteria yeast and mold.4. Preparation of slants /plates /deeps for culture of bacteria yeast and mold.5. Asceptic transfer of microbial cultures.6. To study the morphology of bacteria, yeast and mold.7. .Staining of bacteria (Grams stain).8. The quantitative bacteriological examination of water/milk.9. Determination of phenol coefficient.10. a) Determination of cell mass in a fermentation broth.

b) Calibration of cell mass vs cell number and cell mass vs optical density

CB-222 Biochemistry Laboratory [0 0 3 2]

1. Determination of reducing sugar by dinitro-salicylic (DNS) method.2. Protein estimation by Lowrys method.


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3. Estimation of DNA by diphenylamine reagent method.4. Estimation of RNA by orcinol reagent method.5. Determination of Michaelis constant of enzymes.6. Agarse gel electrophoresis of DNA.7. Determination of isoelectric point of casein.8. Sephadex gel filtration chromatography.9. Extraction of lipids from egg yolk.10. Separation by amino acids by paper electrophoresis.

CB-223 Mechanical Operations Laboratory [0 0 2 1]

1. Determination of power consumption and study of agitation and mixing characteristicof a fluid.

2. Determination of drag coefficient from the plot of drag coefficient Vs modifiedReynolds No.

3. Pressure drop through a packed bed: To plot the graph between modified Reynoldsno. Vs modified friction factor and verify Ergun Equation in packed column.

4. To find out the collection efficiency of a cyclone separator.5. Determination of screening efficiency in a vibrating screen.6. Plate and frame filter press: determination of cake resistance and filter medium

resistance.7. Determination of specific cake resistance in constant pressure vacuum filtrations8. To study filtration characteristics of a leaf filter.9. To study the flow through a helical coil.10. To study the crushing efficiency of a roll crusher.11. To study flow through an orifice meter.

CB-224 Energy Engineering Laboratory [0 0 3 2]

1. To determine the flash point of a given sample.2. To determine the Smoke Point of a given sample3. To study the Distillation of Petroleum Products4. To determine the calorific value of a fuel using Peroxide Bomb Calorimeter5. To determine the sediment in Crude Petroleum and Fuel oils by Extraction6. To determine the Vapour Pressure of a given sample by Reid method7. To determine the Cloud Point and Pour Point of a given sample8. To study the burning properties of a given sample.9. To determine the Melting Point of Petroleum wax

CB-227 Chemical Technology Laboratory [0 0 2 1]

1. To determine the acid value of a vegetable oil.2. To determine the saponification value of vegetable Oil3. To determine the acid value of Lubricating Oil4. To estimate the given reducing sugar5. To estimate the given non reducing sugar6. To study loss on Heating of Tar and Bitumen7. To determine the sediment in Crude Petroleum and Fuel oils8. To determine the viscosity of a given sample by Redwood Apparatus9 To standardize the given Fehlings solution.10. To Study the given polymerization reaction11. To determine the viscosity of a given sample by U-tube viscometer .

CB-300 Practical Training [0 0 0 8]


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Each student is required to undergo compulsory three months practical training in reputedindustry/ CSIR Laboratory or any institute of National Importance including National Instituteof Technology, Jalandhar etc as approved by the Department.

CB-301 Mass Transfer I [3 1 0 4]

Mass Transfer Operations: Classification of mass transfer operation, choice of separationmethods.Diffusion in Mass Transfer: Steady state molecular diffusion in fluids at rest and inlaminar flow, molecular diffusion in gases, molecular diffusion in liquids, diffusivity in liquidsand gases, momentum and heat transfer in laminar flow.Mass Transfer Coefficient: Local and overall mass transfer coefficient, heat and masstransfer analogy, eddy diffusivities, film theory, penetration theory, surface renewal theories,combination film theory and surface stretch theory.Interphase Mass Transfer:Equilibrium, local two phase mass transfer coefficients, Localoverall Mass Transfer coefficients, material balance for co current & counter currentprocesses, cascades and concept of Ideal stage and stage efficiencies, continuous contact

equipments.Gas Absorption: Choice of solvent, Estimation of number of ideal stages Graphical andAnalytical methods, Minimum solvent flow rate, Significance of absorption factor, number oftransfer units and height of a transfer unit (NTU & HTU) concepts, packed column forabsorption, rate of absorption, height of column based on condition in gas film and liquidfilm, height based on overall coefficients, equipment for gas absorptionDrying: Equilibrium in drying, batch drying and rate of batch drying, time of drying, Throughcirculations drying & continuous drying, batch & continuous drying equipments.

Books Recommended

1. Geankopolis C J, Transport Processes and Separation Process Principles, Prentice

Hall of India, 4th Edition, Eastern Economy Edition (2004)2. Treybal R E , Mass Transfer Operations 3rd ed. , McGraw Hill (1980)3. McCabe W L and Smith J C Unit Operations of Chemical Engineering, McGraw

Hill (2001).4. Coulson J M and Richardson J F Chemical Engineering , Vol. 2, 5, McGraw Hill

(1999 )5. Walter L, Badger & Julius T.Banchero Introduction to Chemical Engineering,

McGraw Hill (1997).

CB-302 Mass Transfer II [3 1 0 4]

Mass Transfer equilibria for vapour - liquid, liquid liquid , solid - liquid and solid- gassystemsDistillation : Raoults Law and Daltons law, partial vaporisation and partial condensation,relative volatility, differential distillation & flash distillation, steam distillation, Lewis Sorel andMaCabe Thiele methods & numerical, Ponchon Savarit method, Underwood and Fenskeequations, total reflux , minimum and optimum reflux ratios, multiple feeds and side streamsLiquid Liquid Extraction: Ternary phase diagrams & choice of solvent, single stage andmultistage cross current, co-current and counter current extraction operation for immiscibleand miscible solvents, related numerical problems, continuos contact extractors.Leaching: Mass transfer in leaching, equipment for leaching, single stage and multistagecross current, co-current and counter current leaching operations, related numericalproblems

Adsorption: Introduction and the nature of adsorbent, adsorption equilibria, the Langmuirisotherm , BET isotherm and Gibbs isotherm, potential theory and adsorption equipments.


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Crystallization: Formation of nuclei, nuclei growth and properties of crystals, effect ofimpurities on crystals formation, effect of temperature on solubility, caking of crystals, yieldof crystals, crystallisers, related numerical problems

Books Recommended

1. Geankopolis C J, Transport Processes and Separation Process Principles, PrenticeHall of India, 4th Edition, Eastern Economy Edition (2004)

2. Treybal R E , Mass Transfer Operations 3rd ed. , McGraw Hill (1980)3. McCabe W L and Smith J C Unit Operations of Chemical Engineering, McGraw

Hill (2001).4. Coulson J M and Richardson J F Chemical Engineering , Vol. 2, 5, McGraw Hill

(1999 )5. Walter L, Badger & Julius T.Banchero Introduction to Chemical Engineering,

McGraw Hill (1997).

CB-303 Chemical Reaction Engineering II [3 1 0 4]

Non Ideal Flow: Non ideal flow patterns, E,F &C Curve, Mean residence time, Models fornon ideal flow, N Tanks in series model, conversion in a reactor using RTD data .Heterogeneous Process: Global rates of reaction, Types of Heterogeneous reactionsCatalysis, The nature of catalytic reactions, Mechanism of catalytic reactions.Physical Adsorption and Chemisorption: Physical adsorption and Chemisorption,Adsorption isotherms, Assumptions,Rates of adsorption isotherm, problems.Solid Catalysts : Determination of surface area, Void volume and solid density, Porevolume distribution , Theories of heterogeneous catalysis, Classification of catalysts, catalystpreparation, Promoter and inhibitors, Catalysts DeactivationRate Equations for Fluid solid catalytic reactions: Rates of Adsorption, Surface reaction,Desorption , Rate limiting step, Power Law, Langmuir Hishelwood rate, Eley Rideal

mechanism , Packed bed reactor and fluidized bed reactor, Numerical ProblemsIntra Pellet Mass Transfer : Gaseous diffusion in single cylindrical pore, Different modesof diffusion: Bulk diffusion, Knudsen diffusion and surface diffusion, Diffusion in Liquids,Diffusion in Porous Catalyst, Concepts of effective thermal conductivity and effectivediffusivity, Effectiveness factorsReactors : Fixed Bed Catalytic Reactor, Single and multibed adiabatic reactors, Multitubularfixed bed reactorIntroduction to Fluid Reactions: Kinetic Regimes for Mass Transfer and Reaction, FilmConversion parameter, Clues to the kinetic Regime from solubility data, Clues to theKinetic Regime from equipment, Applications to design

Books Recommended

1. Levenspiel O, Chemical Reaction Engineering, 3rd Ed , John Wiley & Sons,Singapore (1999).

2. Fogler H Scott, Elements of Chemical Reaction Engineering, 3rd ed, Prentice HallInc. (1999).

3. Smith J M , Chemical Engineering Kinetics, McGraw Hill , 3rd ed. (1981).4. Hill, C G, Chemical Engineering Kinetics and Reactor Design, John Wiley (1977).5. Coulson J M and Richardson J F, Chemical Engineering Volume 3, Pergamon

Press (1999).

CB-304 Process Economics and Management [3 0 0 3]


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Cost Estimation: Factors affecting investment & production costs, Capital investments(Fixed and working capital), Types of capital cost estimates, Cost Indexes, Estimatingequipment costs by scaling 6/10 Factor Rule, Purchase Equipment Installation , Insulationcosts, Instrumentation & Control, Piping , Electrical Installation , Service facilities, Land,Engineering . & Supervision , Start up expenses. Methods of Estimating CapitalInvestment, Estimation of total product cost, Different costs involved in the total productfor a typical Chemical Process plant.Interest & Investment Costs : Types of interest ( simple & compound interest ), Nominal& Effective Rates of interest, Continuous interest, Present worth & discounts, perpetuities,capitalized costs, Interest & Investment costs.Taxes & Insurance: Types of taxes, Property taxes, excise taxes, income taxes,Typesof Insurance & Legal Responsibility.Depreciation: Purpose of Depreciation as cost, Types of Depreciation, Depletion, Servicelife., Salvage value, Present value, Methods of Determining Depreciation , Straight- linemethod, Declining Balance Method, Sum of the years Digits method, Sinking Fund Method,Single Unit & Group Depreciation.Profitability, Alternative Investments & Replacement: Profitability standards,

Mathematical methods of profitability evaluation: Rate of return on investment, Discountedcash flow method, Net Present worth, Capitalised costs, pay out period. Determination ofAcceptable investment, Alternatives when an investment must be made, Alternative analysisby method of return on incremental investment, Alternative analysis incorporating minimumreturn as a cost, Replacements, Balance sheets & Income statement.Optimum Design: General procedure for Determining optimum conditions, Procedure withone variable, Procedure with Two or More variables, Break even chart for productionschedule and its significance for optimum analysis. Examples of optimum design in aChemical Process Plant.

Books Recommended

1. Peters, M S & Timmerhaus K D,Plant Design and Economics for ChemicalEngineers, McGraw Hill , New York , 4th Edition (2003)

2. Ulrich , G D, A Guide to Chemical Engineering Process Design and Economics,John Wiley (1984)

3. Guthrie K M, Process Plant Estimation, Evaluation and Control, Craftsman SolanoBeach, California (1974)

4. Douglas, Conceptual Design of Chemical Processes, McGraw Hill (1998)5. Valle Riestra , Project Evaluation in Chemical Process Industries, McGraw Hill

CB-305 Petroleum Refining Engineering [3 1 0 4]

Scope and Purpose of Refining: Global and Indian refining scenario, Petroleum refiningindustry in India practice and prospects, An overview of the entire spectrum of the refineryproducts, refinery configuration development, Physio chemical characteristics of Petroleumand Petroleum productsRefinery Distillation Processes: Desalting and Stabilization of crude, Process descriptionof typical simple distillation, Fractional distillation, crude oil distillation, vacuum distillation etc,

Degree of separation (5-95 gap) and degree of difficulty of separation ( t 50), Packie charts,

ASTM, TBP and EFV Distillation.Fuel Refining: Cracking, coking, reforming, alkylation, isomerisation, polymerization,sweetening, visbreaking.Lube Refining: Solvent extraction, dewaxing, propane deasphalting.

Wax Refining: Deoiling of crude wax, crystallization, catalytic, sweating microcrystalline andpetroleum wax applications.


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Hydro processing: Hydro cracking, hydro treating, hydro finishing.Refinery Feedstock: Nature and effect of different types of refinery feedstock and theirimpurities on refinery configuration and operation.Refinery Gas Processing: Process description of typical light ends unit, acid gas removalusing gas treating processes.Two Phase oil and gas separation equipment : Types, their description , vessel sizing .Theory of separation and separator design.Three phase Oil gas and water separators : Types of separators, their description.Various control and vessel internals, theory and sizing of three phase separator . LACTunits

Books Recommended

1. Nelson W L, Petroleum Refinery Engineering, Mc Graw Hill Book Co. 1985)2. Watkins R N, Petroleum Refinery Distillation, Gulf Publishing Co.3. Gary J H and Handework G E, Petroleum Refining Technology and Economics,

Marcel Dekker, Inc. (2001).

4. Jones D S J, Elements of Petroleum processing, John Wiley & Sons (1995)5. Waquier J P, Petroleum RefiningVol. I & II Editions, Technip (1995)

CB-306 Process Plant Design II [1 0 2 2]

Heat exchangers: Classification of shell and tube heat exchanger, material of construction,cleaning of heat exchangers, heat transfer fluid, agitated vessels, description of shell, tubes,bonnet and channel, pass partition plate, nozzle, baffles, tie rods, baffle spacers, flanges,gaskets and expansion joints.Design of heat exchangers: Energy balance, heat duty consideration and process designof double pipe and shell and tube heat exchangers.Mass Transfer Equipments: Types of mass transfer equipments, packed and tray typetowers.Tray Hydraulics: Bubble cap columns, perforated plate columns and packed towersProcess Design: Process design of tray and packed towers.

Books Recommended

1. Kern D Q, Process Heat Transfer, McGraw Hill (2001)2. Perrys, Handbook of Chemical Engineering McGraw Hill, 7th Ed (1997).3. Coulson J M and Richardson R E, Chemical Engineering Vol 2 and 6, Pergamon

Press (1998).

4. Van Winkle M, Distillation, Ist Ed. , McGraw Hill Company, New York (1967).

5. Ludwig E E, Applied Process Design for Chemical and Petrochemical Plants (Vol.1,2 and 3), 3rd Ed., Gulf Publishing Company, Houston (1995)

CB-307 Bioprocess Engineering [3 1 0 4]Introduction to Bioprocess Engineering: Mass and energy balances in bioprocesses,flow sheet and process calculations, metabolic stoichiometry of growth and productformation, material balance and energy balance with recycle, by pass and purge streams.Microbial Growth Kinetics: Batch, continuous and fed batch, mass balance in series ofvessels, recycle systemMedia Sterilization : Methods of media sterilization, batch and continuous sterilization,kinetics of sterilizationAir Sterilization: Methods of air sterilization, mechanism of air sterilization, filter design.


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Aeration and Agitation: Mass transfer and microbial respiration , bubble aeration andmechanical agitation, correlation between oxygen transfer coefficient and operatingvariables, factors affecting volumetric oxygen transfer, rheology of fermentation fluidsScale Up: Scale up concepts, criteria for bioreactors scale up.Design and Analysis of Bioreactors: Component of fermentors and their design, ascepticoperations, RTD studies in bioreactorsMonitoring of Bioprocesses: On line data analysis for measurement and control ofimportant physicochemical and biochemical parameters, parameter estimation techniquesfor biochemical processes, parameter estimation techniques for biochemical processes,Computer based data acquisition,Modelling and Simulation of Bioprocess: Study of structured models for analysis ofvarious bioprocess, model simulation using software packages

Books Recommended

1. Lee J M, Biochemical Engineering , Prentice Hall (1992)2. Shuler M L, Kargi F, Bioprocess Engineering- Basic Concepts , 2nd ed, Prentice

Hall of India Ltd. ( 2002)3. Aiba S, Humphrey A E and Millis N F ,Biochemical Engineering , Academic Press

(1973)

4. Stanbury P F and Whitaker A, Principles of Fermentation Technolgy, PergamonPress (1995)

5. Bailey J E and Ollis D F, Biochemical Engineering Fundamentals, McGraw Hill(1986)

CB-309 Process Plant Design I [1 0 3 3]

Introduction: Introduction to principles involved in the design and construction of plant.Design preliminaries: Design codes, pressure, temperature, factor of safety, corrosionallowance, weld joint efficiency factor, design loadings, Poissons ratio, dilation of pressurevessels, criteria of failure, material of construction.Storage tanks: Introduction to Indian standards for storage tanks and their use to designcylindrical and spherical vessels under internal pressure, fixed roof and open roof tanks.Mechanical design: Mechanical design of tall vessels for distillation and absorptioncolumns.Design of supports: Design of supports for vertical and horizontal vessels.

Books Recommended

1. Bhattacharya B C, Chemical Equipment Design, CBS Publisher (1985).

2. Sinnott R K , Coulson & Richardson, Chemical Engineering (Vol.6), 2nd

ed,Butterworth Heinemann, Oxford (1998).

3. Ludwig E E, Applied Process Design for Chemical and Petrochemical Plants(Vol.1,2 and 3) , 3rd Ed., Gulf Publishing Company, Houston (1995).

4. Perrys, Handbook of Chemical Engineering, 7th Ed, McGraw Hill (1997).5. Ulrich, G D, A Guide to Chemical Engineering Process Design and Economics,

John Wiley (1984).

CB-310 Bioinfomatics [3 0 0 3]

Introduction and Definition: Definition of Bioinformatics, Applications, InformationNetworks,Biological Databases: Concepts, Introduction to SQL, Various Biological Databases.Computational Biology: Sequence analysis, Pair wise and multiple sequence alignment,


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Similarity searches, Phylogenetic analysis.Bioinformatics Software: Clustal W, oligoprimer. ALSCRIPT, MOLSCRIPT, Rasmol, Phylip,Submitting sequence to databases.Biocomputing Languages: HTML, XML, CML, PERL, UNIX

Books Recommended

1. Westhed D R , Parish J H and Twyman R M, Bioinformatics ,Viva Books Pvt. Ltd. ,New Delhi (2003).

2. Gibas C , Gambeck P Bioinformatics Computer Skills, OReilly, Tokyo3. Attwood T K, and Parry- Smith Introduction to Bioinformatics, Pearson Education ,

Singapore (2000).

4. Mount D W Bioinformatics CBS Publsiher New Delhi (2003).5. Brgeron Bryan, Bioinformatics Computing, Prentice Hall of India (2003).

CB-311 Enzyme Technology [3 0 0 3]

Basic concepts of enzyme: Mechanism of Enzyme Action and kinetic of reaction: Conceptof active sites, and energetics of enzyme substrate complex formation, Specificity of enzymeaction, Estimation of Michaelis-Menten ParameterStability of enzymes: PH, Temperature, Mechanical forces, Heterogeneous system.Production and purification of enzymes: Extract from plant, animal and microbial sources,Methods of characterization of enzymes, Development of enzymatic assays.Enzyme immobilization: Physical and chemical techniques for enzyme immobilizationadsorption, Matrix entrapment, Encapsulation, cross linking, covalent binding, Advantagesand disadvantages of different immobilization techniques.Applications of enzymes: Classification of enzymes, Commercial application of enzymes infood, Pharmaceutical and other industries, Enzymes for analytical and diagnosticapplication.Mass transfer effects in immobilized enzymes: Analysis of film and pore diffusion effectson kinetics of immobilized enzyme reaction, Formulation of dimensionless groups,Calculation of effectiveness factors

Books Recommended

1. Lee J M, Biochemical Engineering , Prentice Hall (1992)2. Bailey and Ollis, Biochemical Engineering Fundamentals, McGraw Hill (1996)3. Lehninger, A L Principles of Biochemistry, Butterworth Publishers,New York(1993)4. Conn E E and .Stumpf P K Outlines of Biochemistry John Wiley and Sons, New

York (1987)

5. Stanbury P F and Whitaker A, Principles of Fermentation Technolgy, Pergamon

Press (1995)

CB-312 Protein Engineering [3 0 0 3]

Structure of protein: Primary, secondary, tertiary, quaternery structure, Protein folding Posttranslation modification.Methods to determine structure of proteins: Protein structure determination, X-Rayanalysis of protein, NMR and mass Spectroscopy, Protein characterization, 2 D GelElectrophoresis.Methods to alter primary structure of protein: Random mutation Site directed mutation,Catalytic activity.Protein engineering benefit: Industry, MedicineStructure and function prediction: Protein Bimolecular interaction, Drug protein interaction


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Books Recommended

1. Lehninger, A L Principles of Biochemistry, Butterworth Publishers, New York(1993)

2. Conn E E and .Stumpf P K Outlines of Biochemistry John Wiley and Sons,New

York (1987)3. Walsh G , Proteins Biochemistry and BiotechnologyJohn Wiley and sons (2003).

4. Permington S R , Dunn M J, Proteomics from Protein sequence to function , VivaBooks Pvt. Ltd., New Delhi

5. Holtje H D, Sippl W and Rognan D , Folkers G , Molecular Modeling, BasicPrinciples and Applications, Wiley VCH Germany (2002).

CB-313 Biopharmaceutical Technology [3 0 0 3]

Introduction to Biopharmaceutical: Biopharmaceutica, Current status and futureprospectsDrug development process: Drug discovery, Patenting, Delivery of pharmaceutical,

Preclinical trials, Drug regulatory authorities.Drug manufacturing process: Manufacturing practice, Facilities, Analysis of products.Pharmaceutical products: Interleukins, interferon, Growth factor, Hormones, Therapeuticenzymes, Antibodies, Vaccines, Nucleic acid therapeutics , Antibiotics.

Books Recommended

1. Leon Lachman tet al Theory and Practice of Industrial Pharmac,, 3 Edition , Leanand Febiger (1986).

2. Remingtons Pharmaceutical Sciences, Mark Publishing and Co. (2000)3. Klefenz H Industrial Pharmaceutical Biotechnology Wiley VCH Verlag GmbH

Germany (1999).4. Vyas S P and Dixit U K Pharmaceutical Biotechnology CBS Publisher New Delhi(2004).

5. Moo- Young Murray , Comprehensive Biotechnology Vol. IV, Pergamon Press NewYork (1985).

CB-314 Petrochemical Technology [3 0 0 3]

Petrochemicals an overview. Growth of Global and Indian petrochemical industry.Petrochemical feed stock.Technologies for the manufacture of Bulk organic Chemicals: Steam Reforming, Syngas manufacture, Steam Cracking, Olefin Separation, Up gradation of C2,C3,C4,C5 cuts,

Separation of ethyl benzene, hydrogen, benzene, toluene, xylene isomersAromatic conversion process: Xylene isomerisation.Manufacture of the major downstream products and their uses, properties: Methanol,Formaldehyde, Ethylene oxide, Ethylene glycol, Poly-vinyl chloride, LDPE and HDPE,Propylene oxide, Iso-Propyl Alcohol, Butadiene, isobutylene, Acetic acid, Maleic anhydride,Nylon 6, Nylon 66, Polyethylene terepthalate, Formaldehyde resins, Styrene ButadieneRubber, Alkyl Benzene Sulfonate, Butanediol, 1,4-butene

Books Recommended

1. Chauvel A Lefebvre G, Petrochemical Process Vol. I & II, Gulf Publishing Company(1989).

2. Rao G, Sitting Drydens Outline of Chemical Technology.3. .Maiti Sukumar, Introduction to Petrochemicals,Oxford & IBH Publishing Co. (1992).


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2. Determination of thermal conductivity of liquid3. Determination of thermal conductivity of insulating powder4. Determination of heat transfer coefficient by natural convection5. Determination of heat transfer coefficient by forced convection6. Determination of heat transfer coefficient for pin fin by natural convection7. Determination of heat transfer coefficient for pin fin by forced convection8. Determination of heat transfer coefficient by dropwise and filmwise condensation9. Determination of overall heat transfer for parallel flow in double pipe heat exchange10. Determination of overall heat transfer coefficient for counter flow in double pipe

heat exchanger11. To conduct test on heat pipe and compare the temperature distribution12. Determination of heat transfer coefficient in shell & tube heat exchanger13. Determination of overall heat transfer coefficient in an open pan evaporator

Note : At least 8 experiments to be performed .

CB-322 Mass Transfer Laboratory [0 0 2 1]

1. To plot the ternary phase diagram for acetic-acid water Toluene2. To draw the tie line and to determine plait point for ternary system3. To determine the diffusivity of acetone in air4. To study the drying characteristics of the given wet material (Natural Convection)5. To determine the Mass Transfer Coefficient for vaporization of naphthalene in air6. To verify Rayleighs Equation for Batch distillation7. To find HETP and HTU for packed distillation column8. To purify turpentine oil having high boiling point using steam distillation9. To determine VLE data for methanol water and to compare it with literature data10. To determine the mass transfer coefficient by carrying out liquid-liquid extraction in a

packed column using acetic acid- toluene-water system

11. To study the drying characteristics of the given wet material (forced convection)12. To study the process of crystallization in an agitated batch crystallizer and to plot a

graph between weight of crystals Vs temp.13. To find out mass transfer coefficient in a drop wise liquid liquid extraction.

Note : At least 8 experiments to be performed

CB-327 Bioprocess Engineering Laboratory [ 0 0 2 1]

1. Sterilization of bio reactor.2. To estimate growth kinetic parameters of Escherichia coli .3. To determine Volumetric Oxygen Transfer Coefficient (kla) in fermentation system by

dynamic method.4. To determine Volumetric Oxygen Transfer Coefficient (kla) in fermentation system by

sulphite oxidation method.5. To determine mixing time in a stirred tank reactor (STR).6. Estimation of cell maintenance coefficient and true growth yield by studying the mass

and energy balance during cell growth.7. Comparison between aerobic and anaerobic fermentation.8. Heat balance across a batch sterilization process.9. To determine the control characteristics of a pH controller.10. To determine Residence Time Distribution (RTD) for a continuous stirred tank reactor

(CSTR).


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CB-400 Project Phase I [0 0 4 2]

Every student will be required to submit a project report in a typed form, on a topicselected by the student, but specifically approved by the faculty member, who will guidethe student or on a topic to be assigned by one or more faculty members.

The project work on the topic will consist of either some investigational work, computersimulation or design problem or experimental set up of some development work of orprototype equipment. Every student will be orally examined in the topic incorporated inthe project and in the project and in the related area of specialization.

The student will be required to submit three copies of his/her project report to thedepartment office for record. One copy each for the department library, participatingfaculty and students own copy.

CB-400 Project (Phase II) [0 0 16 8]

Every student will be required to submit a project report in a typed form, on a topicselected by the student, but specifically approved by the faculty member, who will guidethe student or on a topic to be assigned by one or more faculty members.The project work on the topic will consist of either some investigational work, computersimulation or design problem or experimental set up of some development work of orprototype equipment. Every student will be orally examined in the topic incorporated inthe project and in the project and in the related area of specialization.The student will be required to submit three copies of his/her project report to thedepartment office for recor. One copy each for the department library, participating facultyand students own copy.

CB-401 Chemical Process Control [3 1 0 4]

IntroductionLaplace Transform : Transforms of simple function, Transforms of Derivative, Initial valuetheorem and Final value theorem, Transform of IntegralResponse of First order system: Mercury thermometer & its transfer function, Forcingfunctions, Liquid Level System , Liquid Level Process with constant flow out let,Linearization , Mixing tank & R.C. CircuitResponse of First order system in series: Non interacting System, Interacting SystemHigher order System :Transfer function of second order system, Underdamped System,Impulse function , Sinusoidal function,Transportation lag,Control System : Components of control system, block diagram, Negative and Positivefeed back, Servo problem and Regulation Problem, Development of Block diagram

Controllers and final control element: Control Valve , Proportional controller, Integral &Derivative controller, Comparison.Closed Loop Transfer functions: Determination of transfer functionTransient response of control system: Proportional control for set point change,Proportional control for load change, Proportional Integral control for loadchange,Proportional Integral Control for set point changeStability: Concept of stability, Stability Criteria, Routh test for stabilityIntroduction to frequency response: Bode diagram for first order, Bode diagram forproportional, Integral and derivative control, Second order systemControl System Design by frequency response : Bode stability criteria, Gain and phaseMargin, Ziegler Nichols Controller settings,Advanced Control Strategies: Cascade Control, Feed forward control, Ratio control, Deadtime compensation.


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Books Recommended

1. Coughanower D R, Process System Analysis and Control, McGraw Hill, 2nd ed.(1991)

2. Seborg, Edgar, and Mellichamp, Process Dynamics & Control, John Wiley 2nd. Ed.

(2004)3. Harriot, Process Control, Tata Mcgraw Hill (2000)4. Stephanopoulos, Chemical Process Control - An Introduction To Theory &

Practice, Ist Ed., Prentice Hall of India Private Limited (2003 ).

5. Luyben W L, Essentials Of Process Control McGraw Hill (1997).

CB-402 Industrial Biotechnology [ 3 0 0 3 ]

Introduction to Industrial Biotechnology: Definition and scope of IndustrialBiotechnology, historical overview of industrial fermentation processes and products.Role of Bioprocess Engineer in bioprocess development on an industrial scale,Microorganisms and various unit operations involved, process parameter optimization,

products and market economics relating to modern industrial biotechnology.Raw materials and microorganism for fermentation process: Isolation, preservation andmaintenance and improvement of industrial microorganisms for overproduction of primaryand secondary metabolites, media requirements for fermentation processes, carbon,nitrogen, minerals, vitamins and other nutrients, simple and complex media, mediaeconomics,Production of Primary Metabolites: Organic acids, alcohols, acetone and butanol etc.,

Production of Secondary Metabolites: Antibiotics Beta lactam antibiotics, aminoglycosides, tetracyclines, erythromycin, vitamins and steroids.Commercially Important Products: Enzymes and recombinant proteins havingtherapeutic and diagnostic applications, specialty by products for agricultural, food andpharmaceutical industries, biopesticides, biofertilizer and plant growth stimulants,biopolymers, single cell proteins,bakers yeast, high fructose corn syrup.Biological Waste Treatment : Objective and overview of various aerobic and anaerobicprocess.

Books Recommended

1. Crueger W and Crueger A, Biotechnology : A Text book of Industrial MicrobiologySinouer Associate, Inc. Sunderland MA, USA(1990)

2. Casida L E, Industrial Microbiology, New Age International Publishers Ltd.(2003)

3. Reed G, Prescott and Dunns Industrial Microbiology CBS publishers and

distributors, New Delhi (1987). ,4. Mansi E M T EL, Bryce C F A ,Fermentation Microbiology and Biotechnology. Ane

Books Publishers and Distributors (2003)

5. Kumar H D, A Text book of Biotechnology, EWP (1994).

CB-403 Molecular Biology and Genetic Engineering [3 0 0 3]

Introduction to Molecular Biology and Genetic Engineering: Gene its concepts andinheritence, development of Molecular Biology and Genetic Engineering, DNAstructure,forms and replication, RNAtypes and functions, ribosome and translation, regulation oftranscription and translationGenome Organisation: Genome size and complexity, the super coiling of DNA thestructure of prokaryotic and eukaryotic chromosome, satellite DNA, centromere andtelomere structure.


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Mutation: Spontaneous versus induced mutations, types of mutations, mechanism of DNArepair, mutations frequency gene transfer and expression in bacteria, eukaryotes andviruses.Bacteria: Transformation, transduction and conjugation.Eukaryotes:Transcription, RNA splicing, Retroviruses.Virus: Bacteriophages, genome its organization and its expression, virus of eukaryotes .Basics of Recombinant DNA: Role of genes within cells, elucidation of genetic code,genetic elements that control gene expression, method of creating recombinant DNAresearch, restriction modification enzymes and mapping in eukaryotes, plasmids,bacteriophage lambda and M-13 molecular biology, RNA tumour viruses- replication andfunctionConstruction of c DNA libraries:Construction of genomic and c DNA libraries, methodsof nucleic acid sequencing, expression of cloned genesTools and Techniques: labeling of nucleic acids, hybridization and blotting, PCRsequencingApplication of Recombinant DNA Technology: In agriculture, transgenic plants andanimals, gene therapy, synthesis of important molecules like insulin, growth hormone

interferon etc

Books Recommended

1. De- Robertis, F D P and De Robertis E M F, Cell and Molecular Biology,Saunders,Philadelphia (1991)

2. Lewin B Gene VII, Oxford University Press, Oxford (1990)3. Sambrook J, Fritsch E F and Maniatis T, MolecularCloning ., Cold Spring

Harbor Laboratory Press (1989 )

4. Pelczar M J, Chan E C S and Krieg N R, Microbiology,Mc Graw Hill, New York(1995)

5. Lehninger A L, Principles of Biochemistry, Butterworth Publishers, New York (1993)

CB-404 Environmental Engineering and Safety [3 1 0 4]

Air Pollution: Primary pollutants-particulate matter , dust ,smoke fumes, mist, fog & aerosol,oxides of sulphur , nitrogen oxides. secondary pollutants -sulphur trioxide , Peroxyacetylnitrate, ozone, aldehydes etc. control equipments- collection efficiency, settling chamber,multi tray gravity settling chamber, cyclone separator, electrostatic precipitator, fabric filtersystem, scrubber or wet collectors , spray towers , centrifugal scrubbers, packed bedscrubber, venturi scrubber.Lapse rate : Temperature lapse rate , adiabatic lapse rate. atmospheric stability-inversion, radiation inversion, subsidence inversion, double inversion .plume behaviour .

Water Pollution : Physical characteristics- total solids, odors, temperature , color. chemicalcharacteristics- organic matter , protein , carbohydrates , fats & Oils,BOD, COD , TOC, TOD , ThoD, inorganic matters, pH , chlorides , Alkalinity , nitrogenphosphorus,heavy metals,gases. biological characteristics- microorganism, protista,viruses. primary treatments- pretreatment , sedimentation, floatation. secondary treatments-activated sludge process, trickling filters. tertiary treatments-coagulation and filtrtion , reverseosmosis , ion exchange biological ponds etc.Solid Waste: Solid waste treatment- sanitary landfill, incineration , composting.Safety: Introduction, toxicity, flammability, explosions, pressure& temperature, safetytraining, emergency planning.

Books Recommended


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1. Metcalf and Eddy , Waste Water Treatment Disposal and Reuse ,Tata McGrawHill (2003)

2. Crowl D A, Louvar J F, Chemical Process Safety Fundamentals with applications,2nd Prentice Hall, Englewood Cliffs (2002).

3. Rao C S Environmental Pollution Control Engineering, McGraw Hill (1998 )

4. Pandey G N and Carney G C,Environmental Engineering , McGraw Hill (1995 )5. Coulson J M and Richardson J F , Chemical Engineering,2nd , Vol 6, Pergamon

Press (1999).

CB-405 Industrial Instrumentation [2 0 0 2]

General principles of measurement.Static and dynamic characteristics of instruments.Temperature Measurement: Thermocouples, resistance thermometers, thermistors, opticaland radiation pyrometers.Pressure Measurement: Use of manometers, Bourdon gauge, bellows type gauge,measurement of vacuum and pressure transducers.

Flow Measurement: use of obstruction type meters. Variable area meters. Pressure probes,positive displacement type meters.Liquid level Measurement: Direct and differential method, measurement in open andpressure vessels, measurement of liquid.Measurement of Viscosity, Conductivity, Humidity and pH.Measurement of nuclear radiation. Instrument for gas analysis, gas chromatography, massspectroscopy.Industrial weighing and feeding systems.Process instrumentation, recording instruments, indicating and signalling instruments,transmission of instrument reading, control centre, instrumentation diagram, instrumentationin modern plant.

Books Recommended

1. Eckman D P, Industrial Instrumentation, Wiley Eastern Ltd (1975).

2. Kerk F W, Rimboi W, and Tarapore R, Instrumentation, Wiley and Sons (1983).

3. Considine D N, Process Instruments and Controls Handbook, McGraw Hill (2001).

4. Andrew W G, Applied instrumentation in the Process Industries Vols I,II,III GulfPublishing Company (1987).

5. Instrument Society of America Instrumentation in the chemical and petrochemicalIndustries Vol 8(1984).

CB-410 Immunology [3 0 0 3]

Introduction and Historical Perspective: Innate and acquired immunity, majorcomponents of immune system and their function, concept of antigen, antibody.Cells and Organs of Immune System: Lymphoid cell, heterogenecity of lymphoid cells, T-Cells, primary and secondary lymphoid organs- thymus, bursa of fabricus , spleen,Lymphnodes, lymphatic system,, mucosal associated lymphoid tissue (MALT)Humoral Immunity: B-lymphocytes and their activation , structure and function ofimmunoglobulins, immnunologobulin classes and subclasses, genetic control andproduction, monoclonal antibodies and diagnosis, major histocompatibility complex,complement fixing antibodies and complement cascadeCellular Immunity: Thymus derived lymphocytes (T-cells their classification antigen

presenting cells (APC), Macrophage their origin and function, mechanism of phagocytosis,Identification of cell types of immune systems, immuno suppression and immune tolerance,interferrons and their mechanism of action, interleukins and their functions.


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Immunity and Infection: Hypersensitivity reactions, types and mechanisms of T Cellactivation, Cytokines and their role in immune response, transplantation and rejection, graftrejection, Immunosuppressive drugs, mechanism of immunity, tumor antigens.Immune Disorders and Diseases: Primary immuno deficiency,secondary immuno-deficiency, Acquired immuno deficiency syndrome (AIDS)Auto Immunity: Auto antibodies in humans, Pathogenic mechanisms, experimental modelsof auto immune disease, treatment of autoimmune disorders.Immunological Techniques and Vaccines: Precipitation, agglutination, RIA, ELISA,Immunoelectrophoresis, Immunodiffusion

Books Recommended

1. Kuby J Immunology , W.H. Freeman and Company, New York (2003)2. Roitt I M Essentials of Immunology , Blackwell Scientific Publications

Oxford (1991)

3. Benjamin E and Leskowity S Immunology, A Short Course, Wiley Liss (1991)4. Pelczar M J, Chan E C S and Krieg N R Microbiology,Mc Graw Hill, New York

(1995)5. Pinchuk G, Schaums Outline of Immunology,Tata McGraw Hill (2004)

CB-411 Food Biotechnology [3 0 0 3]

Introduction to Food Biotechnology :- Biotechnological processes in conventional andnon-conventional food, safety aspects, food industry wastesFood Biotechnology Products :- Dairy products, cereal products, fruit and vegetableproducts, meat and fish, food ingredients , High Fructose Corn Syrup , Mycoprotein etc.Flavors and PigmentsBiotechnology and Food Preservation : Different techniques in food preservation,canning, drying ,freezing encapsulation and controlled release of food components,microwave food processing , super critical fluid extraction , accepting processing of food.Genetically Modified and Transgenic Food: Development,processing , nutrition andsafety aspects.Bioreactors in Food Biotechnology: Use of different bioreactors (e.g membranebioreactors) for various food productions, Modelling , simulation and optimization ofindustrial processes, use of sensor and biosensors ,process control.

Books Recommended

1. Angold ,Beech and Taggart Food Biotechnology , Cambridge University Press ,New York (1989)

2. Schwartzberg H G and Rao M A Biotechnology and Food Process Engineering,Marcel Dekker ,IC (1990)

3. Moo- Young Murray , Comprehensive Biotechnology Vol. IV, Pergamon Press NewYork (1985)

4. Moo- Young Murray , Comprehensive Biotechnology Vol. II, Pergamon Press NewYork (1985)

5. Reed G, Prescott and Dunns Industrial Microbiology CBS publishers anddistributors, New Delhi (1987).

CB-412 Cell and Tissue Culture [3 0 0 3]

Plant


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Introduction : Special features and organization of plant cells, totipotency, regeneration ofplants, basic techniques in cell and tissue culture, culture media composition andpreparation, cell growth regulationsCell Cultures : Initiation and maintenance of callus and suspension culture, protoplastisolation, fusion and culture , somatic hybridizationMicropropagation : Techniques, factors affecting morphogenesis and proliferation rate ,technical problems in micro propagation, meristem culture for the production of pathogenfree plants , applications of micro propagation,Biochemistry of major metabolic pathways and products:Autotrophic and heterotrophicgrowth carbon dioxide assimilation, carbohydrate metabolism, nitrogen assimilation.Plant products of industrial importance : Cell suspension culture development andproduction of secondary metabolites by suspension cultures (case studies of azardiractin,podophyllotoxin etc),Biological and technology barriers : Mutation, somaclonal variation , hydrodynamic shearand its quantification, mixing and impeller design aspects.Plant Cell Reactors :Comparison of reactor performance , immobilized plant cell and cellretention reactors.

AnimalIntroduction: Cell and tissue culture media , media optimization (with and without serum )and design asceptic techniques in tissue culture , cell metabolism and regulation, kinetics,storage and preservation of cells, safety considerations in cell culture laboratory .Cell culture : Monolayer culture , microcarrier culture and hybridoma technology ,suspension cell cultures .Animal Cell Bioreactors: Factors affecting mass transfer during growth of cells in culture,criteria of scale up, use of perfusion and hollow fiber rector, harvesting and purificationmethods for end product recovery .Applications:Urokinase production, vaccines, monoclonal antibodies.

Books Recommended

1. Bhojwani S S and Razdan M K,Plant Tissue culture Theory and Practice,Elesevier Science , Netherlands (2004)

2. Narayanswamy S,Plant Cell and Tissue culture, Tata Mc-Graw Hill publishing Co.Ltd. (2002)

3. Freshney R T, Animal cell culture - A Practical approach, Oxford University Press(1987)

4. Spier R R and Griffiths J B,Animal Cell Biotechnology, Academics Press , London(1990)

5. Butler, M Mammalian Cell Biotechnology- A Practical Approach, IRL OxfordUniversity Press (1991)

CB-413 Downstream Processing [3 0 0 3]

Role of downstream processing in biotechnology: role and importance, economics,characterstics of biological mi

Syllabus CBE Sem 3-8

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