Salivary Acini
Salivary Acini
BySecond year studentsSection (4) Group (c)
Under supervision of
Dr/Azza El-Hadidi Dr/Sanaa El-Sherbeni Dr/Ghalia Mahfouz
Salivary Gland
Second Year Section 4 2009/2010
What is the salivary gland?
Simple or compound branched tubuloalvealar gland
Second Year Section 4 2009/2010
Types
Major♥ Submandibular♥ Sublingual♥ Parotid
Minor♥ Buccal♥ Labial♥ Palatine♥ Lingual
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Function Secretion of saliva
Second Year Section 4 2009/2010
structure
Second Year Section 4 2009/2010
stroma
1- Connnective tissue
2- Trabeculae
3- Reticular fibers
Parenchyma 1.Secretory part (salivary acini)
2. Transport system (branching ducts)
Second Year Section 4 2009/2010
Model of the gland: a bunch of grapes: berry= acinusModel of the gland: a bunch of grapes: berry= acinus
stalk of berry: intercalated ductstalk of berry: intercalated duct
Salivary Acini
Second Year Section 4 2009/2010
What is the salivary acini? It the secretory part of
salivary gland
Second Year Section 4 2009/2010
Structure
The salivary acini is composed of a group of secretory cells that surround a central lumen leading to the duct system.
The acinus is surrounded by a basement membrane.
There are branching myoepithelial cells,(basket cells) their contraction squeezes the secretions into the duct.
Second Year Section 4 2009/2010
Classification
According to the nature of secretion
There are 3 types:
Mucous Serous mucoserous
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Mucous acinus
LM Has wide lumen Surrounded by numerous basket cells Secretory cells are cuboidal with distinct
boundries Nucleus is basal flat Cytoplasm is pale foamy
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Basket cellBasket cell
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Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
EM
Cytoplasm contains: rER and mitochondria in the basal part Supranuclear golgi appartus Apical electron lucent mucous granules
Second Year Section 4 2009/2010
Electron lucent
Granules
Second Year Section 4 2009/2010
Serous acinus
LM Dark in staining Has narrow lumen Surrounded by less numerous basket cells Secretory cells are pyramidal with indistinct
boundaries Central rounded nucleus Deep basophilic cytoplasm Apical acidophilic zymogen granules
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
EMCytoplasm contains: Numerous rER and mitochondria in the
around nucleus Supranuclear golgi appartus Apical electron dense secretory granules
Second Year Section 4 2009/2010
Electron denseGranules
Why Crying??
Histology is Easy!!
Mucoserous acinusmixed acinus
Is mainly mucous Surrounded by group of serous cells
called serous demilune or crescent of gianuzzi
Secretion of serous cells passes into canaliculi between mucos cells and lumen of the acinus
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Mucous cellMucous cell
Crescent ofCrescent ofgianuzzigianuzzi
Basket cellBasket cell
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
Important MCQ question
? ? ? ?
1- Mucous acini are lined by cells having
a) Apical zymogen granulesb) Basal rounded nucleic) Indistintinct lateral boundariesd) Ion transport activity e) Non of the aboveAnswer e
Second Year Section 4 2009/2010
2- basket cells are
a) secretory cells
b) Contractile cells
C) endocrine cells
D) connective tissue cells
e) sensory receptor
Answer b
Second Year Section 4 2009/2010
3- serous acini are a) dark in staining b) surrounded by basket cellsc) lined by pyramidal cells with apical
zymogen granulesd) all of the above e) non of the above
Answer d
Second Year Section 4 2009/2010
Second Year Section 4 2009/2010
See you in See you in
another another
presentatiopresentatio
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Second Year Section 4 2009/2010