PowerPoint Presentation for Argalys

ARGALYS

Food Supplements

Beverages

Tablets

High Tech

Plan A novel extraction process with a

substantial difference in performance

Argalys Beverages

Argalys ‘Osmophyt’ Tablets

State of the art formulas

Argalys a unique technology of extraction

Extract the entire cellular content without damaging the actives… an impossible performance with traditional techniques.

Maceration: low yield (single solvent, no input of energy) and high oxidation (process lasts 2 weeks or more)

Decoction: slighly higher yield (single solvent with input of temperature), solution at boiling temperature

= low tech processes are still widely used!!

Flash extraction: the answer!!

Fast complete extraction using several solvents at low temperature (less than 60°c)

Over 90 % of the cellular content is extracted

Specialized equipment (turbosphere) and a unique process with intellectual property

A word on the ‘supercritical‘ method of extraction

The ‘supercritical’ method has some of the same qualities as ‘flash extraction’- fast, low temperature and low oxidation

Flash Extraction Advantages: o Produces a higher yieldo Allows extraction of heavy molecular weight compounds

(proteins, vitamins)o Extracts the full TOTUM of the plant (‘supercritical’ is normally

used to extract one targeted ‘light’ molecule, such as flavor)

Comparing the techniques

Duration process

No. of solvents

Maximum Temp.

Yield ( % of cellular content)

Maceration 20 days 1 ambient 20 /30%

Decoction 12 - 24 hours

1 + 100°c 30/40

Supercritical CO2

1 – 2 hours

1 + 50°c 10 / 60

Flash Extraction 1 - 2 hours

4 + 50°c 90 +

Phytotherapy research refers to the ‘totum’ of the plant = the combination of all the actives which contribute to the functional properties of a given plant

Only Flash Extraction yields an extract like the ‘totum’ of the fresh plant (high yield, no destruction by oxidation or high temperature)

flash extraction: functional interest/temperature

flash extraction: functional interest/temperature

- The structural form of the proteins, (enzymes) + certain vitamins is certainly damaged by an exposure to temperature higher than 50 /60°c

(ex: decoction process)

- The Flash Extraction process preserves those molecules and their natural functional properties

Flash extraction: summary

Innovative & unique Technique based upon specific equipment and a unique process

Almost total and non destructive extraction All the ‘native’ actives are kept unspoiled

(temp, O2) including enzymes & vitamins Demonstrated by analytical results (HPLC,

antioxidant test ‘Orac’ etc..)

Comparison extract Red Vine (vitis vinifera) by colorimetry (measure: ratio concentration/oxidation)

0

0.2

0.4

0.6

0.8

1

1.2

polyphenols Luteoline

Turbosphere

Maceration

Decoction

Beverages:why this form?

Respect for the ‘low temperature’ needs of certain molecules

Liquid form = directly digestible

(no rehydration needed prior to the absorption

of the active)

Argalys’ Osmophyt Tablets:

a true innovationa true innovation Argalys tablets are not made from whole plant powder, but from

extracts obtained by the flash extraction process, then dried under a controlled atmosphere at low temperature (to respect the «temperature sensitivity» of the actives)

After the extraction process the actives are released in solution, then dried.They are not kept ‘prisoner‘ inside of the cellulose wall of the plant cell (in the case of whole plant powder) and therefore are available in the intestine MUCH FASTER, yielding better digestibility

Release of Caffeine in water solvent (37°c pH 2) from fresh Green Tea leaves and HTVE Extract from Green tea

Osmophyt/HTVE: experimental result

Dry extract Osmophyt /Htve:cafein release from guarana (control by hPLC/uv)

Guarana brut

Guarana HTVE

024

6

8

10

12

14

16

Dosages de la caféine par HPLC à détection UV

Guarana brut

Guarana HTVE

12 30 60

Formulation: a new approach Argalys formulas are not ‘about the Plant’ but about a

FUNCTIONAL EFFICACY which generally activates several physiological strategies

Therefore, we develop multi plant formulas, often complemented with essentials oils of the highest purity-aiming at the highest efficacy

Example: «Circulation» which will act on the blood fluidity AND the tonicity of Venous Walls AND the Heart Rhythm a true perceptible effect within the first week.

High Tech Extraction + scientifically developed formulations. Not the typical mono plant powders or tablets !!

Formulation: the FOS FOS: fructo oligo saccharides (from Plant ),

non edulcorant glucides, Bifidogenic Probiotics +++ (helps the development of the bifidogenic flora in the intestine)

Functional interest: o antioxidant protectiono improves the intestinal absorption of nutrients o Speeds up TRANSIT (helps against constipation)

Because of their functional properties , FOS are always a major ingredient in Argalys formulations.

Formulation: other points

No alcohol (less than 0.5%)

No colorants

for all consumers (diabetics,children)

the triple functional efficiency

1° on the functional target

2° as Probiotic (from the FOS)

3° as Natural anti oxydant - a plus for anti ageing properties.

the range Beverages: 200ml for 20/30 days use

Tablets: 3 blisters x 20

B to B: Argalys develops custom made formulas for its distributors, either on new functions ,or adapted to the local pharmacopea, market, etc…

Existing Product Range: Suppleness/Elimination/Tonic/Relax/Memory/Vision/ Menopause (tablets only)/Respiration/Organic Vitamins & Iron/SLIMNESS/ SPORT Range etc…

Argalys Products:

some highlightssome highlights Vision tablets: Anti oxydant value of 300 oranges

(orac test!!)

Menolys (secondary effects of menopause) : high purity of the soybean isoflavones (enables lighter & safer dosification at 8.5%) + anti male hormone effect

Draining: a best seller, and perhaps the best detoxifier on the market

Argalys Slimness: our approach Argalys Slimness acts on the 3 major

parameters which will help weight losses and reduction of cellulitis

Decrease the energy intake (ex: Mucilages of Fucus Alguis)

Increase of the metabolism (Iodine from fucus through higher thyroid activity)

Water retention & draining of cellulitis tissues = a unique product, excellent synergy with low energy diets .

our history

Argalys was founded 2 years ago, (after 10 years of development of the extraction process)

Argalys is a private company

2 years of international propection have confirmed the ‘world class‘ level of our technology and formulation expertise

Argalys: our first references to date

Argalys is distributed as branded product in France, Italy, Portugal and Belgium

Our first major B to B partners: Diafarm Spain Decathlon, France: N°1 distributors in Europe for sports

equipment (3OO retail stores) NPC Dietline, France: a specialist of Protein Diets, looking for

highly synergistic products Famadem, Monte Carlo: also exclusive distributor of Bach’s

flowers in France