Top Banner
INTERNATIONAL FIGURES ON ORGAN DONATION AND TRANSPLANTATION - 2007 2008 SEPTEMBER 2008 Vol. 13. Nº 1
56
Welcome message from author
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
  • INTERNATIONAL FIGURES ON

    ORGAN DONATION AND TRANSPLANTATION - 2007

    2008

    SEPTEMBER 2008

    Vol. 13. N 1

  • AUSTRIAMike Smith (ET)

    BELGIUMMike Smith (ET)

    BULGARIADimitar Brunkov

    CYPRUSGeorge Kyriakides

    CZECH REPUBLICPavel Brezovsky

    DENMARKFrank Pedersen (SKT)

    ESTONIAPeeter Dmitriev

    FINLANDFrank Pedersen (SKT)

    FRANCECristelle Cantrelle

    GERMANYMike Smith (ET)

    GREECEStratos Chatzixiros

    HUNGARYEszter Miskovits

    IRELANDFreda ONeill

    ITALYAndrea Ricci

    LATVIASergej Trushkov

    LITHUANIAJulija irokova

    LUXEMBURGMike Smith (ET)

    NETHERLANDSMike Smith (ET)BIS Foundation

    POLANDJaroslaw CzerwinskiPiotr Malanowski

    PORTUGALMaria Joo Aguiar

    ROMANIARosana TURCU

    SLOVAK REPUBLICLudovit Laca

    SLOVENIAMike Smith (ET)

    SPAINCarmen MartinManuel SerranoDavid UruuelaSilvia Martin

    SWEDENFrank Pedersen (SKT)

    UNITED KINGDOMPhil Pocock

    (ET) EUROTRANSPLANTAustria, Belgium, Croatia,Germany, Luxemburg,Netherlands, Slovenia

    (SKT) SCANDIATRANSPLANTDenmark, Finland, Norway,Sweden, Iceland

    AUSTRALIALee Excell

    CANADALilyanna Trpeski

    CROATIAMike Smith (ET)

    GEORGIAGia Tomadze

    ICELANDFrank Pedersen (SKT)

    ISRAELYael Bistritz

    NEW ZEALANDLee Excell

    NORWAYFrank Pedersen (SKT)

    SWITZERLANDDagmar Vernet

    TURKEYAltay Kken

    UNOS: USAwww.unos.org

    ARGENTINARicardo Ruben Ibarwww.grupopuntacana.org

    BOLIVIAAna Claudia Pacheco

    BRASILAbrahao Salomao Filho

    CHILEwww.grupopuntacana.org

    COLOMBIALuis Eduardo Mejawww.grupopuntacana.org

    CUBAJuan Alberto Falcn AlvarezJuan Carlos Michelenawww.grupopuntacana.org

    DOMINICANAFernando Morales Billini

    ECUADORJose Roberto Proaowww.grupopuntacana.org

    EL SALVADORRal Armando Palomo Escobar

    GUATEMALARudolf A. Garca-Gallont

    HONDURASJuan Ramon Barahona

    MEXICOEnrique Martnez Gutirrez

    PANAMADavid Crespo

    PARAGUAYBlanca Virginia Francowww.grupopuntacana.org

    URUGUAYIns AlvarezRaul Jos Mizrajiwww.grupopuntacana.org

    VENEZUELACarmen Luisa Lattuf de Milanswww.grupopuntacana.org

    GRUPO PUNTA CANAArgentina, Brasil, Bolivia, Chile,Colombia, Costa Rica, Cuba,Dominicana, Ecuador, ElSalvador, Guatemala,Honduras, Mxico, Panam,Paraguay, Per, Puerto Rico,Uruguay, Venezuelawww.grupopuntacana.org

    INTERNATIONAL FIGURES ON ORGAN, TISSUE &HEMATOPOIETIC STEM CELL DONATION &

    TRANSPLANTATION ACTIVITIES. DOCUMENTS PRODUCEDBY THE COMMITTEE OF EXPERTS ON THE

    ORGANISATIONAL ASPECTS OF CO-OPERATION INORGAN TRANSPLANTATION (2007)

    Editors: Rafael Matesanz

    NATIONAL DATA PROVIDED BY:

    Data recorded & prepared by Organizacin Nacional de Trasplantes (ONT) SpainRafael MatesanzBeatriz MahilloMarina Alvarez

    Foot Note: For the purposes of this Newsletter the following definitions were used:Organ donor: Every potential donor transferred to the operating theatre from whom, at least, one solid organ has been retrievedMultiorgan donor: Every donor from whom, at least, two different solid organs have been retrievedAbsolute number: Include all figures corresponding to all donors/patients adults and childrenPaediatric: Includes only paediatric activity (patients under 15 years old)

    AULA MDICA EDICIONES. C/ Isabel Colbrand, 10-12 nave 78 planta 2 28050 Madrid (Espaa)Tlf. 91 358 64 78 Fax. 91 358 99 79. Depsito legal: M-9.990-1996

  • 1NEWSLETTER

    TRANSPLANT 2008

    INTERNATIONAL FIGURES ON ORGAN DONATION AND TRANSPLANTATION. YEAR 2007............................ 3

    INTERNATIONAL DATA ON ORGAN DONATION AND TRANSPLANTATION,WAITING LIST AND FAMILY REFUSALS. YEAR 2007. ........................................................................... 23

    INTERNATIONAL DATA ON TISSUES AND HEMATOPOIETIC STEM CELL TRANSPLANTATION.YEAR 2007...................................................................................................................................... 37

    DOCUMENTS PRODUCED BY THE TRANSPLANT COMMITTEE OF THE COUNCIL OF EUROPE.YEAR 2008...................................................................................................................................... 43

    - RESOLUTION CM/RES(2008)4 ON ADULT-TO-ADULT LIVING DONOR LIVER TRANSPLANTATION ................. 44

    - RESOLUTION CM/RES(2008)6 ON TRANSPLANTATION OF KIDNEYS FROM LIVING DONORSWHO ARE NOT GENETICALLY RELATED TO THE RECIPIENT .................................................................... 46

    CONTENTS

  • 3International figures onorgan donation and

    transplantation. Year 2007

  • 414.5

    14.117.2

    19.9

    19.2

    9.2

    15.95

    13.2

    20.1

    1.7

    22.3

    15.0

    13.1

    11.4

    1.3

    5.8

    3.0

    8.5

    20.5

    34.3

    25.3

    21.1

    21.0

    13.2

    16.9

    28.15

    2.1 10.7

    23.9

    18.7

    DECEASEDORGANDONORS

    AnnualRatep.m.p.2007

  • 527.9

    24.431.0

    36.9

    36.2

    17.1

    28.4

    21.0

    36.65

    3.3

    40.5

    26.3

    14.9

    14.9

    1.5

    9.2

    5.3

    25.7

    8.2

    27.2

    45.9

    42.3

    34.95

    33.6

    23.5

    28.4

    42.4

    25.2 21.3

    42.2

    31.3

    DECEASEDDONOR

    KIDNEY

    TRANSPLANT

    AnnualRatep.m.p.2007

  • 6LIVINGKIDNEY

    TRANSPLANT

    AnnualRatep.m.p.2007

    13.4

    2.71.0

    18.2

    24.4

    3.8

    0.6

    6.9

    10.2

    2.6

    7.2

    7.5

    1.7

    0.5

    2.2

    7.9

    12.1

    51.4

    1.8

    9.4

    1.7

    3.0

    3.7

    3.3

    1.2

    13.4

    22.0

    4.0

    13.0

    3.5

    0.4

  • 7KIDNEY

    TRANSPLANT

    -includedallthecombinations-

    AnnualRatep.m.p2007

    41.3

    27.132.8

    55.0

    22.4

    40.0

    17.7

    35.3

    31.3

    39.3

    10.6

    47.95

    28.0

    14.9

    15.5

    3.8

    17.1

    1.8

    17.4

    77.1

    17.6

    28.9

    48.9

    46.0

    38.3

    34.8

    36.8

    50.2

    46.3

    25.2 34.4

    45.7

    31.7

  • 8LIVER

    TRANSPLANT

    AnnualRatep.m.p.2007

    14.8

    2.710.0

    15.3

    1.5

    5.1

    14.0

    7.9

    1.5

    14.3

    5.04.1

    5.2

    1.0

    2.9

    6.3

    6.0

    18.4

    24.6

    16.8

    11.2

    14.0

    10.7

    9.1

    25.2

    11.5

    25.1

  • 9HEARTTRANSPLANT

    Heart-LungTransp.Included

    AnnualRatep.m.p.2007

    5.0

    4.44.2

    7.7

    1.7

    5.0

    5.3

    4.1

    0.4

    6.9

    2.2

    1.35

    5.5

    0.4

    0.5

    0.8

    2.5

    5.35

    5.3

    6.1

    6.7

    1.7

    2.3

    3.2

    7.0

    3.8

    4.8

    1.3

  • 10

    LUNGTRANSPLANT

    Single+DoubleLung

    Heart-LungTransp.Included

    AnnualRatep.m.p.2007

    4.7

    1.22.8

    6.1

    2.0

    3.45

    6.0

    9.9

    0.2

    0.0

    5.1

    1.9

    4.1

    3.5

    1.2

    1.0

    2.0

    4.0

    8.8

    4.5

    0.4

  • 11

    PANCREASTRANSPLANT

    includedallthecombinations

    AnnualRatep.m.p.2007

    1.1

    3.0

    0.55

    1.6

    3.0

    0.5

    0.0

    0.7

    0.1

    1.1

    1.3

    1.7

    1.5

    2.6

    1.2

    4.1

    1.7

    1.7

    1.8

  • 12

    KIDNEY-PANCREAS

    TRANSPLANT

    AnnualRatep.m.p.2007

    1.1

    3.0

    0.55

    1.4

    2.4

    0.5

    0.0

    0.0

    0.7

    0.8

    1.0

    1.5

    1.3

    2.1

    1.2

    3.3

    1.5

    1.5

    1.8

  • 13

    Population (million inhabitants) 492.3

    Deceased D. - included NHBD - (Rate - pmp -) 8293 (16.85)NHB Donors (pmp) 486 (1.0)% Multiorgan donors -

    KIDNEY

    TX included all the combinations - (pmp) 17306 (35.2)% (Living TX/ Total TX) 16.9Paediatric

  • 14

    CANAD

    USA

    AUSTRALIA

    NEW

    ZEALAND

    POPULATION:303.9millions

    (pmp)

    DeceasedOrganDonor

    8089(26.6)

    DeceasedDonorKidneyTX.10587(34.8)

    LivingKidneyTransplant

    6038(19.9)

    LiverTransplant

    6493(21.4)

    HeartTransplant

    2210(7.3)

    Heart-LungTransplant

    30(0.1)

    S.Lung+D.LungTX.

    1469(4.8)

    PancreasTransplant

    1331(4.4)

    POPULATION:33.4millions

    (pmp)

    DeceasedOrganDonor

    493(14.8)

    DeceasedDonorKidneyTX.

    763(22.8)

    LivingKidneyTransplant

    480(14.4)

    LiverTransplant

    488(14.6)

    HeartTransplant

    173(5.2)

    Heart-LungTransplant

    4(0.1)

    S.Lung+D.LungTX.

    183(5.5)

    PancreasTransplant

    73(2.2)

    POPULATION

    :21millions

    (pmp)

    DeceasedOrganDonor

    198(9.4)

    DeceasedDonorKidneyTX.

    342(16.2)

    LivingKidneyTransplant

    268(12.7)

    LiverTransplant

    151(7.1)

    HeartTransplant

    62(2.9)

    Heart-LungTransplant

    6(0.2)

    S.Lung+D.LungTX.

    79(3.7)

    PancreasTransplant

    28(1.3)

    POPULATION

    :4.2

    millions

    (pmp)

    DeceasedOrganDonor

    38(8.9)

    DeceasedDonorKidney

    TX.

    65(15.3)

    LivingKidneyTransplant

    58(13.7)

    LiverTransplant

    34(8.0)

    HeartTransplant

    12(2.8)

    Heart-LungTransplant

    -

    S.Lung+D.LungTX.

    13(3.0)

    PancreasTransplant

    1(0.2)

  • 15

    DECEASEDORGANDONORS

    AnnualRatep.m.p.2007

    3.3

    0.1

    1.4

    3.1

    4.2

    1.8

    9.6

    3.6

    5.5

    2.7 18.2

    12.35

    8.1

    X17.8

  • 16

    DECEASEDDONORKIDNEY

    TRANSPLANT/LIVING

    KIDNEY

    TRANSPLANT

    AnnualRatep.m.p.2007

    5.0

    14.75

    2.7

    7.7

    6.2

    2.6

    4.0

    4.4

    - 5.4

    - 0.5

    13.3

    1.4

    0.1

    6.4 6.8

    5.7

    14.8

    1.3

    0.8

    3.15

    0.5

    3.4

    0.0

    0.1 18.3

    3.9

    13.7-

    29.1

    1.8

    9.85 6.7

  • 17

    KIDNEY

    TRANSPLANT

    -includedallthecombinations-

    AnnualRatep.m

    .p2007

    3.9

    8.4

    3.9

    19.7

    6.5

    10.5 5.4

    16.1

    8.9

    12.55

    16.6

    30.9

    22.1

    13.7

    0.1

    14.8 0.5

  • 18

    LIVER

    TRANSPLANT

    AnnualRatep.m.p.2007

    0.9

    0.1

    4.1

    0.4

    5.1

    1.2

    6.9

    4.5

    3.4

  • 19

    HEARTTRANSPLANT

    Heart-LungTransp.Included

    AnnualRatep.m.p.2007

    0.1

    1.3

    0.8

    0.3 1.2

    2.1

    1.0

    0.6

    0.2

  • 20

    LUNGTRANSPLANT

    Single+DoubleLung

    Heart-LungTransp.Included

    AnnualRatep.m.p.2007

    0.15

    0.0

    0.3

    0.6

    0.6

    0.4

  • 21

    PANCREASTRANSPLANT

    includedallthecombinations

    AnnualRatep.m.p.2007

    0.2

    0.9

    0.6

    1.8

    0.1

    0.0

  • 22

    Latin-America Data on Organ Donationand Transplantation Activity

    Population (million inhabitants) 516.7

    Deceased Organ D. - included NHBD - (Rate - pmp -) 2918 (5.65)NHB Donors (pmp) -% Multiorgan donors -

    KIDNEY

    TX included all the combinations - (pmp) 8179 (15.8)% (Living TX/ Total TX) -Paediatric

  • 23

    International data on organdonation and transplantation,waiting list and family refusals.

    Year 2007

  • 24

    EUROPEANUNION

    COUNTRIES

    AUSTRIA

    BELGIUM

    BULGARIA

    CYPRUS

    CZECH.R.

    DENMARK

    ESTONIA

    FINLAND

    FRANCE

    GERMANY

    Population

    (millioninhabitants)

    8.3

    10.6

    7.0

    0.7

    10.3

    5.5

    1.3

    5.3

    63.2

    82.3

    DONATION

    DeceasedOrgan

    D.-

    included

    NHBD-

    (Rate-pm

    p-)

    185(22.3)

    298(28.15)

    9(1.3)

    -217(21.1)

    72(13.2)

    25(19.2)

    91(17.2)

    1601

    (25.3)

    1313

    (15.95)

    NHBDonors(pmp)

    6(0.7)

    39(3.7)

    0-

    2(0.2)

    -0

    -39

    (0.6)

    -%

    Multiorgan

    donors

    97.8

    91.9

    66-

    54.85

    62.5

    862.9

    9496.1

    TRANSPLANTATION

    KIDNEY

    TXincluded

    allthe

    combinations

    -(pmp)

    398(47.95)

    491(46.3)

    27(3.8)

    54(77.1)

    394(38.3)

    171(31.3)

    52(40.0)

    173(32.8)

    2911

    (46.0)

    2907

    (35.3)

    %(LivingTX/TotalTX)

    15.6

    8.6

    59.2

    66.7

    8.2

    32.75

    9.6

    2.9

    8.1

    19.5

    Paediatric

  • 25

    EUROPEANUNION

    COUNTRIES

    GREECE

    HUNGARY

    IRELAND

    ITALY

    LATVIA

    LITHUANIA

    LUXEMBOURG

    NETHERLANDS

    POLAND

    Population

    (millioninhabitants)

    11.0

    10.1

    4.2

    58.2

    2.3

    3.4

    0.5

    16.4

    38.2

    DONATION

    DeceasedOrgan

    D.-

    included

    NHBD-

    (Rate-pm

    p-)

    64(5.8)

    151(15.0)

    88(21.0)

    1194

    (20.5)

    43(18.7)

    48(14.1)

    1(2.1)

    277(16.9)

    352(9.2)

    NHBDonors(pmp)

    -0

    00

    120

    -114(7.0)

    0%

    Multiorgan

    donors

    -45

    -71.2

    945.8

    100

    98.6

    57

    TRANSPLANTATION

    KIDNEY

    TXincluded

    allthe

    combinations

    -(pmp)

    188(17.1)

    282(28.0)

    146(34.8)

    1684

    (28.9)

    73(31.7)

    92(27.1)

    12(25.2)

    824(50.2)

    674(17.7)

    %(LivingTX/TotalTX)

    46.3

    63.4

    5.9

    1.4

    9.8

    043.7

    3.3

    Paediatric

  • 26

    EUROPEANUNION

    NONEUROPEANUNION

    COUNTRIES

    PORTUGAL

    ROMANIA

    SLOVAKR.

    SLOVENIA

    SPAIN

    SWEDEN

    U.K.

    AUSTRALIA

    CANADA

    Population

    (millioninhabitants)

    10.6

    21.0

    5.3

    2.0

    45.2

    9.2

    60.2

    21.0

    33.4

    DONATION

    DeceasedOrgan

    D.-

    included

    NHBD-

    (Rate-pm

    p-)

    252(23.9)

    36(1.7)

    107(20.1)

    23(11.4)

    1550

    (34.3)

    133(14.5)

    793(13.2)

    198(9.4)

    493(14.8)

    NHBDonors(pmp)

    00

    0-

    88(2.0)

    -186(3.1)

    19(0.9)

    22(0.7)

    %Multiorgan

    donors

    76.6

    72.2

    44.9

    100

    8481.2

    79.1

    8198.5

    TRANSPLANTATION

    KIDNEY

    TXincluded

    allthe

    combinations

    -(pmp)

    483(45.7)

    222(10.6)

    209(39.3)

    31(15.5)

    2211

    (48.9)

    379(41.3)

    2218

    (36.8)

    610(29.0)

    1243

    (37.2)

    %(LivingTX/TotalTX)

    7.7

    68.5

    6.7

    3.2

    6.2

    32.45

    36.25

    4438.6

    Paediatric

  • 27

    NONEUROPEANUNION

    COUNTRIES

    CROACIA

    GEORGIA

    ICELAND

    ISRAEL

    N.ZEALAND

    NORWAY

    SWITZERLAND

    TURKEY

    USA

    Population

    (millioninhabitants)

    4.4

    5.0

    0.3

    7.2

    4.2

    4.7

    7.6

    75.2

    303.9

    DONATION

    DeceasedOrgan

    D.-

    included

    NHBD-

    (Rate-pm

    p-)

    58(13.1)

    -0

    61(8.5)

    38(8.9)

    94(19.9)

    81(10.7)

    223(3.0)

    8089

    (26.6)

    NHBDonors(pmp)

    --

    0-

    --

    -0

    -%

    Multiorgan

    donors

    94.8

    -0

    63.9

    8485.1

    87.65

    --

    TRANSPLANTATION

    KIDNEY

    TXincluded

    allthe

    combinations

    -(pmp)

    66(14.9)

    9(1.8)

    7(22.4)

    127(17.6)

    123(29.0)

    260(55.0)

    261(34.4)

    1310

    (17.4)

    16625(54.7)

    %(LivingTX/TotalTX)000

    0100

    100

    53.5

    47.15

    33.1

    37.9

    69.5

    36.3

    Paediatric

  • 28

    LATINAMERICA

    COUNTRIES

    ARGENTINA

    BOLIVIA

    BRASIL

    CHILE

    COLOMBIA

    CUBA

    COSTARICA

    DOMINICANA

    ECUADOR

    Population

    (millioninhabitants)

    39.3

    9.8

    191.3

    16.6

    47.0

    11.3

    4.5

    9.1

    13.0

    DONATION

    DeceasedOrgan

    D.-included

    NHBD-

    (Rate-pm

    p-)

    486(12.35)

    -1049

    (5.5)

    135(8.1)

    449(9.6)

    200(17.8)

    19(4.2)

    1(0.1)

    23(1.8)

    NHBDonors(pmp)

    --

    --

    --

    --

    -%

    Multiorgan

    donors

    52.05

    --

    --

    41-

    --

    TRANSPLANTATION

    KIDNEY

    TXincluded

    allthe

    combinations

    -(pmp)

    867(22.1)

    72(0.1)

    3170

    (16.6)

    228(13.7)

    758(16.1)

    166(14.8)

    38(8.4)

    59(6.5)

    51(3.9)

    %(LivingTX/TotalTX)

    17.7

    68.1

    40.6

    -8.3

    9.6

    52.6

    98.3

    80.4

    Paediatric

  • 29

    LATINAMERICA

    COUNTRIES

    ELSALVADOR

    GUATEMALA

    HONDURAS

    PANAMA

    MEXICO

    PARAGUAY

    URUGUAY

    VENEZUELA

    Population

    (millioninhabitants)

    7.1

    13.2

    8.0

    3.5

    105.8

    6.4

    3.3

    27.5

    DONATION

    DeceasedOrgan

    D.-included

    NHBD-

    (Rate-pm

    p-)

    -18

    (1.4)

    -11

    (3.1)

    351(3.3)

    17(2.7)

    60(18.2)

    99(3.6)

    NHBDonors(pmp)

    --

    --

    --

    --

    %Multiorgan

    donors

    --

    --

    --

    36.7

    4

    TRANSPLANTATION

    KIDNEY

    TXincluded

    allthe

    combinations

    -(pmp)

    38(5.4)

    138(10.5)

    4(0.5)

    31(8.9)

    2087

    (19.7)

    25(3.9)

    102(30.9)

    345(12.55)

    %(LivingTX/TotalTX)

    100

    73.9

    100

    2974.8

    885.9

    46.1

    Paediatric

  • 30

    EUROPEANUNION

    COUNTRIES

    AUSTRIA

    BELGIUM

    BULGARIA

    CYPRUS

    CZECH.R.

    DENMARK

    ESTONIA

    FINLAND

    FRANCE

    Population

    8.3

    10.6

    7.0

    0.7

    10.3

    5.5

    1.3

    5.3

    63.2

    WAITINGLIST

    KIDNEY

    NTX

    CENTRES

    --

    11

    74

    11

    44

    Patientsadmitted

    totheWLduring2007

    380

    420

    294

    10408

    201

    67196

    3510

    PatientsawaitingforaTX

    by2007,31stDec

    852

    840

    947

    114

    525

    385

    52252

    6491

    Patientsdead

    whileon

    theWLduring2007

    3726

    2810

    2536

    412

    128

    ESRDon

    dialysistreatmentduring2007

    --

    2887

    240

    --

    296

    --

    LIVER

    NTX

    CENTRES:

    --

    2-

    21

    11

    24

    Patientsadmitted

    totheWLduring2007

    191

    299

    29-

    156

    402

    551348

    PatientsawaitingforaTX

    by2007,31stDec

    113

    176

    89-

    6621

    17

    575

    Patientsdead

    whileon

    theWLduring2007

    4940

    6-

    132

    11

    113

    HEART

    NTX

    CENTRES:

    --

    1-

    22

    -1

    25

    Patientsadmitted

    totheWLduring2007

    7798

    14-

    8123

    -16

    540

    PatientsawaitingforaTX

    by2007,31stDec

    5234

    87-

    6414

    -5

    298

    Patientsdead

    whileon

    theWLduring2007

    1313

    15-

    123

    -1

    82

    LUNG

    NTX

    CENTRES:

    --

    0-

    11

    -1

    12

    Patientsadmitted

    totheWLduring2007

    104

    900

    -31

    28-

    11287

    PatientsawaitingforaTX

    by2007,31stDec

    103

    520

    -47

    32-

    0168

    Patientsdead

    whileon

    theWLduring2007

    55

    0-

    139

    -1

    43

    PANCREAS

    NTX

    CENTRES:

    --

    0-

    10

    -0

    11

    Patientsadmitted

    totheWLduring2007

    2434

    0-

    30-

    --

    105

    PatientsawaitingforaTX

    by2007,31stDec

    3237

    0-

    37-

    --

    151

    Patientsdead

    whileon

    theWLduring2007

    1-

    0-

    3-

    --

    5

    SMALL

    BOWEL

    NTX

    CENTRES:

    --

    0-

    00

    -0

    4

    Patientsadmitted

    totheWLduring2007

    --

    0-

    --

    --

    14

    PatientsawaitingforaTX

    by2007,31stDec

    --

    0-

    --

    --

    20

    Patientsdead

    whileon

    theWLduring2007

    --

    0-

    --

    --

    1

  • 31

    EUROPEANUNION

    COUNTRIES

    GERMANY

    GREECE

    HUNGARY

    IRELAND

    ITALY

    LATVIA

    LITHUANIA

    LUXEMBURG

    NETHERLANDS

    Population

    82.3

    11.0

    10.1

    4.2

    58.2

    2.3

    3.4

    0.5

    16.4

    WAITINGLIST

    KIDNEY

    NTX

    CENTRES:

    -4

    41

    431

    2-

    -

    Patientsadmitted

    totheWLduring2007

    2956

    273

    227

    219

    2932

    4264

    0869

    PatientsawaitingforaTX

    by2007,31stDec

    8207

    903

    705

    433

    7098

    301

    211

    10937

    Patientsdead

    whileon

    theWLduring2007

    314

    1444

    16143

    1125

    695

    ESRDon

    dialysistreatmentduring2007

    --

    6992

    --

    01276

    --

    LIVER

    NTX

    CENTRES:

    -2

    11

    220

    2-

    -

    Patientsadmitted

    totheWLduring2007

    1590

    4468

    481347

    012

    0140

    PatientsawaitingforaTX

    by2007,31stDec

    1940

    2459

    161492

    028

    -132

    Patientsdead

    whileon

    theWLduring2007

    308

    423

    8226

    04

    -16

    HEART

    NTX

    CENTRES:

    -1

    21

    191

    2-

    -

    Patientsadmitted

    totheWLduring2007

    707

    831

    -539

    314

    069

    PatientsawaitingforaTX

    by2007,31stDec

    839

    1019

    -863

    526

    -47

    Patientsdead

    whileon

    theWLduring2007

    166

    23

    -102

    16

    -19

    LUNG

    NTX

    CENTRES:

    -1

    01

    130

    2-

    -

    Patientsadmitted

    totheWLduring2007

    448

    510

    -195

    00

    0106

    PatientsawaitingforaTX

    by2007,31stDec

    594

    25

    -307

    02

    -162

    Patientsdead

    whileon

    theWLduring2007

    971

    2-

    720

    0-

    17

    PANCREAS

    NTX

    CENTRES:

    -0

    21

    130

    0-

    -

    Patientsadmitted

    totheWLduring2007

    212

    06

    9111

    00

    016

    PatientsawaitingforaTX

    by2007,31stDec

    247

    016

    25258

    00

    -29

    Patientsdead

    whileon

    theWLduring2007

    160

    20

    60

    0-

    5

    SMALL

    BOWEL

    NTX

    CENTRES:

    -0

    -0

    30

    0-

    -

    Patientsadmitted

    totheWLduring2007

    -0

    --

    80

    00

    PatientsawaitingforaTX

    by2007,31stDec

    -0

    --

    200

    0-

    -

    Patientsdead

    whileon

    theWLduring2007

    -0

    --

    10

    0-

    -

  • 32

    EUROPEANUNION

    COUNTRIES

    POLAND

    PORTUGAL

    ROMANIA

    SLOVAKR.

    SLOVENIA

    SPAIN

    SWEDEN

    U.K.

    Population

    38.2

    10.6

    21.0

    5.3

    2.0

    45.2

    9.2

    60.2

    WAITINGLIST

    KIDNEY

    NTX

    CENTRES:

    178

    54

    -44

    425

    Patientsadmitted

    totheWLduring2007

    1404

    650

    350

    214

    55-

    347

    2954

    PatientsawaitingforaTX

    by2007,31stDec

    1621

    2324

    1626

    546

    844291

    338

    8876

    Patientsdead

    whileon

    theWLduring2007

    4197

    15121

    1-

    21636

    ESRDon

    dialysistreatmentduring2007

    15000

    9554

    6500

    0-

    21974

    --

    LIVER

    NTX

    CENTRES:

    53

    10

    -28

    39

    Patientsadmitted

    totheWLduring2007

    269

    -187

    019

    1461

    143

    790

    PatientsawaitingforaTX

    by2007,31stDec

    171

    -313

    09

    696

    40316

    Patientsdead

    whileon

    theWLduring2007

    30-

    310

    8175

    7255

    HEART

    NTX

    CENTRES:

    44

    22

    -20

    38

    Patientsadmitted

    totheWLduring2007

    205

    -30

    2822

    330

    44210

    PatientsawaitingforaTX

    by2007,31stDec

    214

    -80

    1130

    9722

    112

    Patientsdead

    whileon

    theWLduring2007

    27-

    123

    233

    1146

    LUNG

    NTX

    CENTRES:

    11

    20

    -9

    26

    Patientsadmitted

    totheWLduring2007

    15-

    60

    -230

    26228

    PatientsawaitingforaTX

    by2007,31stDec

    24-

    200

    -133

    24284

    Patientsdead

    whileon

    theWLduring2007

    0-

    20

    -24

    2136

    PANCREAS

    NTX

    CENTRES:

    32

    31

    -11

    38

    Patientsadmitted

    totheWLduring2007

    2330

    420

    1103

    13320

    PatientsawaitingforaTX

    by2007,31stDec

    1031

    840

    187

    24354

    Patientsdead

    whileon

    theWLduring2007

    23

    80

    -3

    034

    SMALL

    BOWEL

    NTX

    CENTRES:

    00

    00

    -2

    13

    Patientsadmitted

    totheWLduring2007

    00

    00

    -8

    -14

    PatientsawaitingforaTX

    by2007,31stDec

    00

    00

    -8

    -2

    Patientsdead

    whileon

    theWLduring2007

    00

    00

    -2

    -5

  • 33

    NONEUROPEANUNION

    COUNTRIES

    AUSTRALIA

    CANADA

    CROATIA

    ICELAND

    ISRAEL

    N.ZEALAND

    NORWAY

    SWITZERLAND

    TURKEY

    USA

    Population

    21.0

    33.4

    4.4

    0.3

    7.2

    4.2

    4.7

    7.6

    75.2

    303.9

    WAITINGLIST

    KIDNEY

    NTX

    CENTRES:

    2224

    -1

    63

    16

    37250

    Patientsadmitted

    totheWLduring2007

    --

    712

    -320

    -158

    362

    -33875

    PatientsawaitingforaTX

    by2007,31stDec

    1388

    4195

    378

    -540

    559

    195

    681

    14450

    76313

    Patientsdead

    whileon

    theWLduring2007

    -193

    5-

    33-

    1819

    -4563

    ESRDon

    dialysistreatmentduring2007

    --

    --

    --

    --

    42500

    -

    LIVER

    NTX

    CENTRES:

    89

    -0

    31

    13

    23117

    Patientsadmitted

    totheWLduring2007

    --

    99-

    81-

    68135

    -11081

    PatientsawaitingforaTX

    by2007,31stDec

    198

    635

    59-

    117

    3112

    116

    1165

    16230

    Patientsdead

    whileon

    theWLduring2007

    -78

    14-

    29-

    016

    -1614

    HEART

    NTX

    CENTRES:

    511

    --

    31

    13

    12131

    Patientsadmitted

    totheWLduring2007

    --

    19-

    52-

    3141

    -3111

    PatientsawaitingforaTX

    by2007,31stDec

    100

    124

    12-

    115

    65

    24172

    2607

    Patientsdead

    whileon

    theWLduring2007

    -22

    1-

    16-

    26

    -324

    LUNG

    NTX

    CENTRES:

    56

    -0

    21

    12

    1267

    Patientsadmitted

    totheWLduring2007

    --

    --

    68-

    3250

    -1959

    PatientsawaitingforaTX

    by2007,31stDec

    141

    234

    --

    705

    4236

    12117

    Patientsdead

    whileon

    theWLduring2007

    -40

    --

    16-

    66

    -277

    PANCREAS

    NTX

    CENTRES:

    26

    -0

    31

    12

    37141

    Patientsadmitted

    totheWLduring2007

    --

    17-

    13-

    1833

    -2512

    PatientsawaitingforaTX

    by2007,31stDec

    4880

    6-

    225

    1746

    323931

    Patientsdead

    whileon

    theWLduring2007

    -6

    1-

    --

    11

    -267

    SMALL

    BOWEL

    NTX

    CENTRES:

    -4

    -0

    1-

    01

    018

    Patientsadmitted

    totheWLduring2007

    --

    --

    1-

    --

    1281

    PatientsawaitingforaTX

    by2007,31stDec

    --

    --

    1-

    --

    1233

    Patientsdead

    whileon

    theWLduring2007

    --

    --

    --

    --

    -37

  • 34

    LATINAMERICA

    COUNTRIES

    ARGENTINA

    BOLIVIA

    BRASIL

    COSTARICA

    CUBA

    ECUADOR

    MEXICO

    PANAMA

    URUGUAY

    VENEZUELA

    Population

    39.3

    9.8

    191.3

    4.5

    11.3

    13.0

    105.8

    3.5

    3.3

    27.5

    WAITINGLIST

    KIDNEY

    NTX

    CENTRES:

    523

    227

    17

    -199

    14

    10

    Patientsadmitted

    totheWLduring2006

    1552

    --

    36150

    176

    3214

    15116

    390

    PatientsawaitingforaTX

    by2006,31stDec

    4663

    -35090

    501441

    125

    1398

    134

    416

    803

    Patientsdead

    whileon

    theWLduring2006

    246

    --

    340

    -63

    1212

    16

    ESRDon

    dialysistreatmentduring2006

    24835

    1085

    --

    --

    -890

    2422

    9163

    LIVER

    NTX

    CENTRES:

    17-

    561

    3-

    48-

    -1

    Patientsadmitted

    totheWLduring2006

    455

    --

    -59

    -221

    -8

    4

    PatientsawaitingforaTX

    by2006,31stDec

    453

    -6453

    -12

    -62

    -19

    12

    Patientsdead

    whileon

    theWLduring2006

    95-

    --

    5-

    40-

    -2

    HEART

    NTX

    CENTRES:

    28-

    621

    1-

    35-

    3-

    Patientsadmitted

    totheWLduring2006

    141

    --

    28

    -40

    -19

    -

    PatientsawaitingforaTX

    by2006,31stDec

    115

    -315

    11

    -17

    -22

    -

    Patientsdead

    whileon

    theWLduring2006

    53-

    --

    --

    6-

    3-

    LUNG

    NTX

    CENTRES:

    9-

    111

    1-

    9-

    --

    Patientsadmitted

    totheWLduring2006

    53-

    --

    --

    4-

    2-

    PatientsawaitingforaTX

    by2006,31stDec

    76-

    136

    --

    --

    -2

    -

    Patientsdead

    whileon

    theWLduring2006

    14-

    --

    --

    1-

    --

    PANCREAS

    NTX

    CENTRES:

    7-

    791

    2-

    19-

    1-

    Patientsadmitted

    totheWLduring2006

    118

    --

    --

    -2

    -3

    -

    PatientsawaitingforaTX

    by2006,31stDec

    67-

    740

    --

    -1

    -16

    -

    Patientsdead

    whileon

    theWLduring2006

    --

    --

    --

    --

    --

    SMALL

    BOWEL

    NTX

    CENTRES:

    3-

    --

    --

    --

    --

    Patientsadmitted

    totheWLduring2006

    4-

    --

    --

    --

    --

    PatientsawaitingforaTX

    by2006,31stDec

    4-

    --

    --

    --

    --

    Patientsdead

    whileon

    theWLduring2006

    --

    --

    --

    --

    --

  • 35

    COUNTRIES

    BULGARIA

    ESTONIA

    FRANCE

    GREECE

    HUNGARY

    IRELAND

    ITALY

    LATVIA

    LITHUANIA

    Population

    (millioninhabitants)

    7.0

    1.3

    63.2

    11.0

    10.1

    4.2

    58.2

    2.3

    3.4

    FAMILYREFUSALS

    Num

    berofinterviews,asking

    forconsenttodonation

    1641

    -161

    254

    146

    2200

    3273

    Num

    beroffamilyrefusals(%)

    7(43.75)

    16(39.0)

    889

    70(43.5)

    11(4.3)

    12(8.2)

    683(31.05)

    11(34.4)

    28(38.4)

    COUNTRIES

    POLAND

    ROMANIA

    SPAIN

    U.K.

    ISRAEL

    NORWAY

    TURKEY

    Population

    (millioninhabitants)

    38.2

    21.0

    45.2

    60.2

    7.2

    4.7

    75.2

    FAMILYREFUSALS

    Num

    berofinterviews,asking

    forconsenttodonation

    466

    701987

    1403

    145

    122

    594

    Num

    beroffamilyrefusals(%)

    52(11.2)

    34(48.6)

    335(16.8)

    844(60.2)

    84(57.9)

    28(22.3)

    349(58.75)

    COUNTRIES

    ARGENTINA

    CHILE

    COLOMBIA

    CUBA

    PANAMA

    PARAGUAY

    URUGUAY

    VENEZUELA

    Population

    (millioninhabitants)

    39.3

    16.6

    47.0

    11.3

    3.5

    6.4

    3.3

    27.5

    FAMILYREFUSALS

    Num

    berofinterviews,asking

    forconsenttodonation

    1135

    --

    226

    24-

    74208

    Num

    beroffamilyrefusals(%)

    549(48.0)

    -(41.0)

    -(34.5)

    26(11.5)

    13(54.2)

    -(30.0)

    27(36.5)

    65(31.25)

    EUROPEANUNION

    EUROPEANUNION

    NONEUROPEANUNION

    LATINAMERICA

  • 37

    International data on tissueand hematopoietic

    stem cell transplantation.Year 2007

  • 38

    EUROPEANUNION

    COUNTRIES

    BULGARIA

    CZECHR.

    ESTONIA

    FRANCE

    GREECE

    ITALY

    LITHUANIA

    PORTUGAL

    ROMANIA

    SPAIN

    SLOVAKIA

    U.K.

    Population(millioninhabitants)

    7.0

    10.3

    1.3

    63.2

    11.0

    58.2

    3.4

    10.6

    21.0

    45.2

    5.3

    60.2

    TISSUEACTIVITY

    INDICATORS

    MuscleSkeletalTissue

    NofBanks

    224

    1-

    16

    22

    437

    2-

    NDeceaseddonors(pmp)

    405(57.8)

    128(12.4)

    1(0.8)

    --

    309(5.3)

    4(12.0)

    36(3.4)

    5(0.2)

    585(12.9)

    18(3.3)

    -

    NLiving

    donors(pmp)

    01171

    (113.8)-

    --

    2815

    (48.4)

    57(16.8)

    -198(9.4)

    2633

    (58.25)

    84(15.3)

    -

    NGraftedPatients(pmp)

    255(36.4)

    1177

    (114.4)-

    18367(290.5)

    -4959

    (85.2)

    59(17.4)

    -204(9.7)

    6465

    (143.7)

    425(77.3)

    -

    NBankProcessed

    Pieces(pmp)

    2817

    (402.0)-

    198(152.3)

    14875(235.3)

    -9543

    (164.0)

    69(20.3)

    -296(14.1)

    9326

    (206.3)

    564(102.5)

    -

    PercentageofDiscarded

    Pieces

    2-

    --

    --

    17-

    27.25

    11-

    -

    TypesofTissuesDistributed:Bone%

    75-

    --

    --

    --

    --

    --

    (frozen/freeze-dry/demineralized)

    0-

    --/-/725

    -66/7/2

    --

    --

    100/-/-

    -

    TypesofTissuesDistributed:Tendons%

    86-

    -20

    -25

    --

    --

    6-

    Corneas

    NofBanks

    13

    2-

    1213

    29

    122

    36

    NDeceaseddonors(pmp)

    56(8.0)

    438(42.5)

    21(15.7)

    -61

    (5.5)

    5985

    (102.8)

    20(5.9)

    -15

    (0.7)

    2512

    (55.6)

    124(22.5)

    2622

    (43.55)

    NGraftedPatients(pmp)

    77(11.0)

    876(85.15)

    56(41.8)

    3732

    (59.0)

    275(25.0)

    4196

    (72.1)

    37(10.9)

    525(49.7)

    23(1.1)

    3031

    (67.1)

    183(33.3)

    2176

    (36.15)

    NBankProcessed

    Pieces(pmp)

    98(14.0)

    --

    7777

    (123.0)

    -11033(189.6)

    39(11.5)

    -26

    (1.2)

    4608

    (101.95)

    237(43.1)

    5239

    (87.0)

    PercentageofDiscarded

    Pieces

    1-

    --

    --

    2.5

    -11.1

    --

    26.6

    VascularTissue

    NofBanks

    03

    --

    -5

    12

    128

    2-

    NDeceaseddonors(pmp)

    012

    (1.2)

    --

    -159(2.7)

    7(2.1)

    -0

    220(4.9)

    5(0.9)

    -

    -NLiving

    donors(pmp)

    0-

    --

    -801(13.8)

    --

    0-

    --

    -N-GraftedPatients(pmp)

    06(0.6)

    -866(13.7)

    -266(4.6)

    1(0.3)

    -0

    78(1.7)

    7(1.3)

    -

    NBankProcessed

    Pieces(pmp)

    0-

    -3114

    (49.3)

    -1109

    (19.1)

    7(2.1)

    -0

    205(4.5)

    10(1.8)

    -

    PercentageofDiscarded

    Pieces

    0-

    --

    --

    85.7

    -0

    14.7

    --

    TypesofTissuesDistributed:Artery

    0-

    -332

    -41

    --

    -100

    --

    TypesofTissuesDistributed:Vein

    0-

    -534

    -59

    --

    --

    --

    Valves

    NofBanks

    02

    --

    -5

    13

    128

    1-

    NDeceasedDonors(pmp)

    083

    (8.1)

    --

    -234(4.0)

    19(5.6)

    -0

    239(5.3)

    24(4.4)

    -

    NGraftedPatients(pmp)

    083

    (8.1)

    -93

    (1.5)

    -171(2.9)

    11(3.2)

    -0

    105(2.3)

    9(1.6)

    -

    NBankProcessed

    Pieces(pmp)

    0-

    -534(8.4)

    -413(7.1)

    33(9.7)

    -0

    420(9.3)

    39(7.1)

    -

    PercentageofDiscarded

    Pieces

    0-

    --

    --

    66.6

    -0

    30-

    -

    TypesofTissuesDistributed:Aortic

    0-

    -30

    -40

    --

    -44

    10-

    TypesofTissuesDistributed:Pulmonary

    0-

    -60

    -60

    --

    -56

    90-

    TypesofTissuesDistributed:Tricuspid

    0-

    --

    --

    --

    --

    --

    TypesofTissuesDistributed:Mitral

    0-

    -3

    --

    --

    --

    --

    TypesofTissuesDistributed:Other

    0-

    --

    --

    --

    --

    --

  • 39

    EUROPEANUNION

    COUNTRIES

    BULGARIA

    CZECHR.

    ESTONIA

    FRANCE

    GREECE

    ITALY

    LITHUANIA

    PORTUGAL

    ROMANIA

    SPAIN

    SLOVAKIA

    U.K.

    Population(millioninhabitants)

    7.0

    10.3

    1.3

    63.2

    11.0

    58.2

    3.4

    10.6

    21.0

    45.2

    5.3

    60.2

    TISSUEACTIVITY

    INDICATORS

    Skin

    NofBanks

    22

    --

    15

    -1

    614

    2-

    NDeceaseddonors(pmp)

    102(14.5)

    11(1.1)

    --

    6(0.5)

    293(5.0)

    -5(0.4)

    9(0.4)

    83(1.8)

    --

    NLiving

    donors(pmp)

    05(0.5)

    --

    --

    -31

    (1.5)

    --

    -

    NGraftedpatients(pmp)

    168700

    5(0.5)

    -308357

    -1458

    (25.1)

    -19

    (0.9)

    71(1.6)

    --

    (24100.0)

    (4877.6)

    NBankProcessed

    Pieces(pmp)

    358500

    --

    262148

    -804910

    -46500

    266120

    --

    (51214.0)

    (4146.7)

    (13830.1)

    (2214.3)

    (5887.6)

    PercentageofDiscarded

    Pieces

    0-

    --

    --

    -1

    --

    -

    CellCultures

    NofBanks

    04

    --

    --

    -0

    133

    -

    NDeceaseddonors(pmp)

    0-

    --

    --

    -0

    --

    -

    NLiving

    Donors(pmp)

    0115(11.2)

    --

    --

    -0

    -81

    (14.7)

    -

    NGraftedPatients(pmp)

    0115(11.2)

    --

    --

    -0

    94(2.1)

    74(13.45)

    -

    NBankProcessed

    Pieces(pmp)

    0-

    --

    --

    -0

    94(2.1)

    --

    PercentageofDiscarded

    Pieces

    0-

    --

    --

    -0

    --

    -

    TypesofTissuesDistributed:Chondrocytes0

    --

    --

    --

    -35.1

    10-

    TypesofTissuesDistributed:Keratinocytes

    0-

    --

    --

    --

    64.9

    17-

    TypesofTissuesDistributed:Other

    0-

    --

    --

    --

    -3

    -

  • 40

    NONEUROPEANUNION

    LATINAMERICA

    COUNTRIES

    ISRAEL

    NETHERLANDS

    TURKEY

    ARGENTINA

    BRASIL

    CUBA

    PANAMA

    MEXICO

    URUGUAY

    VENEZUELA

    Population(millioninhabitants)

    7.2

    16.4

    75.2

    39.3

    191.3

    11.3

    3.5

    105.8

    3.3

    27.5

    TISSUEACTIVITY

    INDICATORS

    MuscleSkeletalTissue

    NofBanks

    11

    -16

    6-

    -3

    1-

    NDeceaseddonors(pmp)

    24(3.3)

    119(7.3)

    -82

    (2.0)

    -34

    (3.0)

    --

    23(7.0)

    -

    NLiving

    donors(pmp)

    --

    -471(12.7)

    --

    --

    --

    NGraftedPatients(pmp)

    -1175

    (71.65)

    -942(24.1)

    -31

    (2.7)

    --

    135(40.9)

    -

    NBankProcessed

    Pieces(pmp)

    --

    -492(12.6)

    -34

    (3.0)

    --

    887(268.8)

    -

    PercentageofDiscarded

    Pieces

    --

    -38

    --

    --

    10-

    TypesofTissuesDistributed:Bone%

    --

    --

    --

    --

    --

    (frozen/freeze-dry/demineralized)

    --

    -60/10/30

    --

    --

    41/658/62

    -

    TypesofTissuesDistributed:Tendons%

    --

    --

    --

    --

    -

    Corneas

    NofBanks

    -2

    1723

    29-

    161

    11

    NDeceaseddonors(pmp)

    289(40.1)

    1341

    (81.8)

    876(11.65)

    798(20.0)

    11073(57.9)

    665(59.3)

    20(5.7)

    856(8.1)

    73(22.1)

    58(2.1)

    NGraftedPatients(pmp)

    -810(49.4)

    1262

    (16.8)

    1035

    (26.0)

    -558(49.8)

    35(10.0)

    1215

    (11.5)

    103(31.2)

    108(3.9)

    NBankProcessed

    Pieces(pmp)

    -1810

    (110.4)

    964(12.8)

    1596

    (40.9)

    -1120

    (100.0)

    1(0.0)

    -147(44.5)

    116(4.2)

    PercentageofDiscarded

    Pieces

    --

    -53.6

    -15.7

    2029

    13.6

    6.9

    VascularTissue

    NofBanks

    -1

    -2

    --

    --

    1-

    NDeceaseddonors(pmp)

    -24

    (1.5)

    -98

    (2.5)

    --

    --

    16(4.8)

    -

    NLiving

    donors(pmp)

    --

    --

    --

    --

    47(14.2)

    -

    NGraftedPatients(pmp)

    -0

    -20

    (0.5)

    --

    --

    --

    NBankProcessed

    Pieces(pmp)

    -3(0.2)

    -30

    (0.8)

    --

    --

    36(10.9)

    -

    PercentageofDiscarded

    Pieces

    --

    -35

    --

    --

    5.5

    -

    TypesofTissuesDistributed:Artery

    --

    -30

    --

    --

    100

    -

    TypesofTissuesDistributed:Vein

    --

    -70

    --

    --

    -

    Valves

    NofBanks

    31

    35

    1-

    -1

    1-

    NDeceasedDonors(pmp)

    30(4.2)

    375(22.9)

    223(3.0)

    263(6.7)

    --

    --

    8(2.4)

    -

    NGraftedPatients(pmp)

    -103(6.3)

    159(2.1)

    305(7.8)

    --

    --

    7(2.1)

    -

    NBankProcessed

    Pieces(pmp)

    -279(17.0)

    -360(9.2)

    --

    --

    11(3.3)

    -

    PercentageofDiscarded

    Pieces

    --

    -33

    --

    --

    --

    TypesofTissuesDistributed:Aortic

    --

    -60

    --

    --

    2-

    TypesofTissuesDistributed:Pulmonary

    --

    -40

    --

    --

    5-

    TypesofTissuesDistributed:Tricuspid

    --

    --

    --

    --

    --

    TypesofTissuesDistributed:Mitral

    --

    --

    --

    --

    --

    TypesofTissuesDistributed:Other

    --

    --

    --

    --

    --

  • 41

    NONEUROPEANUNION

    LATINAMERICA

    COUNTRIES

    ISRAEL

    NETHERLANDS

    TURKEY

    ARGENTINA

    BRASIL

    CUBA

    PANAMA

    MEXICO

    URUGUAY

    VENEZUELA

    Population(millioninhabitants)

    7.2

    16.4

    75.2

    39.3

    191.3

    11.3

    3.5

    105.8

    3.3

    27.5

    TISSUEACTIVITY

    INDICATORS

    Skin

    NofBanks

    11

    -4

    1-

    -2

    1-

    NDeceaseddonors(pmp)

    54(7.5)

    531(32.4)

    -77

    (2.0)

    --

    --

    30(9.1)

    -

    NLiving

    donors(pmp)

    --

    --

    --

    --

    -

    NGraftedpatients(pmp)

    --

    72(1.8)

    --

    --

    28(8.5)

    -

    NBankProcessed

    Pieces(pmp)

    --

    120000

    --

    --

    40500

    -

    (3053.0)

    (12272.7)

    PercentageofDiscarded

    Pieces

    --

    10-

    --

    -3.1

    -

    CellCultures

    NofBanks

    --

    --

    --

    --

    -

    NDeceaseddonors(pmp)

    --

    --

    --

    --

    -

    NLiving

    Donors(pmp)

    --

    --

    --

    --

    -

    NGraftedPatients(pmp)

    --

    --

    --

    --

    -

    NBankProcessed

    Pieces(pmp)

    --

    --

    --

    --

    -

    PercentageofDiscarded

    Pieces

    --

    --

    --

    --

    -

    TypesofTissuesDistributed:Chondrocytes

    --

    --

    --

    --

    -

    TypesofTissuesDistributed:Keratinocytes

    --

    --

    --

    --

    -

    TypesofTissuesDistributed:Other

    --

    --

    --

    --

    -

  • 42

    COUNTRIES

    BULGARIA

    ESTONIA

    FRANCE

    GREECE

    HUNGARY

    ITALY

    LITHUANIA

    POLAND

    Population(millioninhabitants)

    7.0

    1.3

    63.2

    11.0

    10.1

    58.2

    3.4

    38.2

    HEMATOPOIETICSTEM

    CELLTRANSPLANTS

    Autologous

    1932

    2847

    83200

    2958

    50484

    Allogeneicrelated

    73

    614

    5742

    864

    19148

    Allogeneicunrelated

    37

    765

    5144

    495

    35143

    Total

    2942

    4226

    191

    286

    4317

    104

    775

    COUNTRIES

    PORTUGAL

    ROMANIA

    SPAIN

    SWITZERLAND

    TURKEY

    Population(millioninhabitants)

    10.6

    21.0

    45.2

    7.6

    75.2

    HEMATOPOIETICSTEM

    CELLTRANSPLANTS

    Autologous

    244

    721312

    309

    476

    Allogeneicrelated

    589

    427

    75-

    Allogeneicunrelated

    430

    280

    68-

    Total

    345

    812019

    452

    853

    COUNTRIES

    ARGENTINA

    BRASIL

    CUBA

    PANAMA

    URUGUAY

    VENEZUELA

    Population(millioninhabitants)

    39.3

    191.3

    11.3

    3.5

    3.3

    27.5

    HEMATOPOIETICSTEM

    CELLTRANSPLANTS

    Autologous

    384

    879

    171

    6932

    Allogeneicrelated

    150

    562

    62

    1035

    Allogeneicunrelated

    37121

    --

    21

    Total

    571

    1562

    233

    8168

    EUROPEANUNION

    NONEUROPEANUNION

    EUROPEANUNION

    LATINAMERICA

  • 43

    Documents Producedby the Transplant Committeeof the Council Of Europe.

    Year 2008

  • The Committee of Ministers, in its compositionrestricted to the representatives of the States Parties tothe Convention on the elaboration of a EuropeanPharmacopoeia1,

    Considering that the aim of the Council of Europe isto achieve greater unity between its members and thatthis aim may be pursued, inter alia, by the adoption ofcommon action in the public health field;

    Having regard to the Convention for the Protection ofHuman Rights and Dignity of the Human Being withregard to the Application of Biology and Medicine(Convention on Human Rights and Biomedicine ETSNo. 164), and in particular Article 19 (General rule) andArticle 20 (Protection of persons not able to consent toorgan removal) thereof;

    Having regard also to the Additional Protocol to theConvention on Human Rights and Biomedicineconcerning Transplantation of Organs and Tissues ofHuman Origin (ETS No. 186), and, in particular, ChapterIII (Organ and tissue removal from living persons);

    Recalling its Resolution (78) 29 on the harmonisationof legislation of member states relating to removal,grafting and transplantation of human substances;

    Recalling its Recommendation Rec(2001)5 tomember states on the management of organ transplantwaiting lists and waiting times;

    Recalling its Recommendation Rec(2004)7 tomember states on organ trafficking;

    Recognising that, in facilitating the transplantation oforgans in the interest of patients in Europe, there is aneed to protect individual rights and freedoms and toprevent the commercialisation of parts of the humanbody involved in organ procurement, exchange andallocation activities;

    Considering that organ transplantation is awell-established, life-saving, and effective treatment andmay be the only treatment available for some forms ofend-stage organ failure;

    Aware of the fact that tissue and cell transplantationmay be life saving or life enhancing;

    Concerned by the universal shortage of organs fortransplantation;

    Considering that adult-to-adult living donor livertransplantation (Domino liver transplantation, i.e.transplantation into a recipient whose own organ wasrespected and transplanted into another recipient, isexcluded from the scope of this resolution) may beenvisaged when suitable organs from deceased donorsare not available, provided that all safeguards areimplemented in order to guarantee the freedom andsafety of the donor and a successful transplant in therecipient;

    Convinced also that adult-to-adult living donor livertransplantation is an effective treatment for end-stageliver disease, with the potential benefit of reducingmortality of patients awaiting a transplantation;

    Conscious of the risks that living donor livertransplantation may have for the donor and of the needto ensure that all measures are taken to safeguard thedonors health;Recalling that no organ removal may be carried out

    on a person who does not have the capacity toconsent;

    44

    RESOLUTION CM/RES(2008)4ON ADULT-TO-ADULT LIVING DONOR LIVER

    TRANSPLANTATION

    (Adopted by the Committee of Ministers on 12 March 2008at the 1021st meeting of the Ministers' Deputies)

    1 States concerned: Austria, Belgium, Bosnia and Herzegovina,Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Fin-land, France, Germany, Greece, Hungary, Iceland, Ireland, Italy,Latvia, Lithuania, Luxembourg, Malta, Montenegro, Netherlands,Norway, Poland, Portugal, Romania, Serbia, Slovak Republic, Slo-venia, Spain, Sweden, Switzerland, the former Yugoslav Republicof Macedonia, Turkey and United Kingdom.

  • 45

    Recommends to member states the following:

    1. to instruct the organisation responsible foraccrediting transplantation programmes andregulating the allocation of organs to addressexplicitly the issue of adult-to-adult living donorliver transplantation and establish transplantationprogrammes accredited to perform this type oftransplantation;

    2. to ensure that adult-to-adult living donor livertransplantation programmes adhere to thefollowing minimum requirements:

    a. substantial experience in liver surgery andliver transplantation;

    b. an active liver-transplantation programme;c. significant mortality in the waiting list;d. a multidisciplinary team experienced in routineand complex liver surgery, covering alloperative

    e. aspects (pre-operative, peri-operative andpost-operative);

    3. to ensure that the indications for adult-to-adultliving donor liver transplantation are recognisedindications for deceased donor livertransplantation;

    4. to ensure that the organisation responsible for theallocation of organs and accreditation oftransplantation programmes establishes clearconditions under which adult-to-adult living donorliver transplantation is ethically acceptable,namely:

    a. adult-to-adult living donor liver transplantationis only to be performed withinauthorised/licensed programmes with ongoingfeedback;

    b. the donor and the recipient have a closepersonal relationship as required and definedby law;

    c. each single procedure should be approved ona case-by-case basis;

    d. the motive to donate is solely altruistic. Anyfinancial gain or comparable advantage inconnection with the donation is consideredillegal;

    e. the donor has been given appropriateinformation as to the purpose and nature ofthe removal as well as on its consequencesand risks. The donor has also beeninformed of the rights and the safeguardsprescribed by law for his or her protection,in particular of the right to have access to

    independent advice about such risks by ahealth professional having appropriateexperience and who is not involved in theorgan removal or subsequenttransplantation procedures. Finally, thedonor is provided with comprehensiveinformation on:

    i. the alternatives to adult-to-adult livingdonor liver transplantation;

    ii. the previous experience of the centrewhere the procedure will be carried out;

    iii. the risks of morbidity and mortality of theprocedure for the donor and the recipient;

    iv. the likely long-term outcome for therecipient;

    f. the living donor has given free, informed andspecific consent either in written form orbefore an official body; the donor may freelywithdraw consent at any time;

    g. the donor has been properly screened toidentify any physical or psychologicalcontra-indication; the removal may not becarried out if there is a serious risk to the lifeor health of the donor;

    5. to ensure immediate access to the emergencywaiting list for organs from deceased donors incase of failure of the remnant liver in the donor orgraft failure in the recipient and that specific rulesfor non-residents apply according to nationalregulations;

    6. to ensure that the necessary conditions andprovisions are in place for long-term medicalfollow up of both donor and recipient, includingthe monitoring of the short- and long-term effectsof transplantation on the health of donors, by theestablishment of national registries;

    7. to guarantee equitable access to livertransplantation services for all patients in need ofa liver transplant, regardless of personal financialmeans;

    8. to ensure that all costs related to the operationsand follow-up of donor and recipient are covered,according to the competent organisations ownprocedures;

    9. to provide for a system of fair compensation forany person who suffered undue damage resultingfrom transplantation procedures, according to theconditions and procedures prescribed by law.

  • 46

    The Committee of Ministers, in its compositionrestricted to the representatives of the States Partiesto the Convention on the Elaboration of a EuropeanPharmacopoeia1,

    Considering that the aim of the Council of Europeis to achieve greater unity between its members andthat this aim may be pursued, inter alia, by theadoption of common action in the health field;

    Taking into account its Resolution (78) 29 on theharmonisation of legislation of member statesrelating to removal, grafting and transplantation ofhuman substances and the final text of the 3rdConference of European Health Ministers (Paris,16-17 November 1987);

    Having regard to the Convention for the Protectionof Human Rights and Dignity of the Human Being withregard to the Application of Biology and Medicine(Convention on Human Rights and Biomedicine ETSNo. 164), and in particular to Article 19 (General rule)and Article 20 (Protection of persons not able toconsent to organ removal) thereof;

    Having regard also to the Additional Protocol tothe Convention on Human Rights and Biomedicineconcerning the Transplantation of Organs andTissues of Human Origin (ETS No. 186);

    Recalling its Recommendation Rec(2001)5 to themember states on management of organ transplantwaiting lists and waiting times;

    Recalling its Recommendation Rec(2004)7 to themember states on organ trafficking;

    Recognising that, in facilitating the transplantationof organs in the interests of patients in Europe, there

    is a need to protect individual rights and freedomsand to prevent the commercialisation of parts of thehuman body involved in organ procurement,exchange and allocation activities;

    Recalling the principle that organ removal can beundertaken on a living donor only in the case wherea suitable organ from a deceased donor is notavailable and only when no alternative therapeuticmethod of comparable effectiveness is available;

    Considering that there is a shortage of kidneys fortransplantation to patients having reached the endstage of renal failure;

    Taking note that the increasing number oftransplantations of organs from living donors is oneway of reducing the increasing gap between thegrowing number of patients waiting for kidneytransplantation and the limited number of organsprocured from deceased donors;

    Stressing that transplantation of a kidney from aliving donor to a genetically related recipient is awell-established practice in most of the StatesParties to the Convention and that in somecountries living donor kidney transplantationsaccount for a large proportion of the transplantsperformed each year;

    Knowing that there is very good evidence that livingdonor kidney transplants, even if the donor is notgenetically related to the recipient, lead to similar or

    RESOLUTION CM/RES(2008)6ON TRANSPLANTATION OF KIDNEYS FROM LIVINGDONORS WHO ARE NOT GENETICALLY RELATED

    TO THE RECIPIENT(Adopted by the Committee of Ministers on 26 March 2008

    at the 1022nd meeting of the Ministers Deputies)

    1 States concerned: Austria, Belgium, Bosnia and Herzegovina,Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Fin-land, France, Germany, Greece, Hungary, Iceland, Ireland, Italy,Latvia, Lithuania, Luxembourg, Malta, Montenegro, Netherlands,Norway, Poland, Portugal, Romania, Republic of Serbia, SlovakRepublic, Slovenia, Spain, Sweden, Switzerland, the former Yu-goslav Republic of Macedonia, Turkey and United Kingdom.

  • 47

    better clinical outcomes than with kidneys transplantedfrom deceased donors;

    Stressing that living donor kidney transplants allowfor the optimum treatment of receiving a transplantbefore going on to dialysis (pre-emptive transplant);

    Taking into consideration that the removal of akidney from a carefully selected, healthy individualcarries a low risk of complications and has not beenshown to have long-term effects on the health of sucha donor;

    Recalling that no organ removal may be carried outon a person who does not have the capacity toconsent,

    Recommends to the governments of States Partiesto the Convention to take note of the general principlesand measures listed in the attached appendix whenthey draw up the regulations and procedures relatingto the donation of a kidney in view of transplantationby a living donor non genetically linked to the receiver:

    Appendix to Resolution CM/Res(2008)6

    1. States Parties to the Convention may permit thetransplantation of kidneys from non-geneticallyrelated living donors on condition that:

    - the living donor and the recipient have arelationship as required and defined by law;the donor has been given appropriateinformation as to the purpose and nature ofthe removal as well as on its consequencesand risks. The donor has also beeninformed of the rights and the safeguardsprescribed by law for his or her protection, inparticular of the right to have access toindependent advice about such risks by ahealth professional having appropriateexperience and who is not involved in theorgan removal or subsequent transplantationprocedures;

    - the living donor has given free, informed andspecific consent, either in written form orbefore an official body; the donor may freelywithdraw consent at any time;

    - no pressure is exerted on the living donorinto donation;

    - the organ does not, as such, give rise tofinancial gain or comparable advantage;

    - the living donor has been properly screenedto identify any physical or psychologicalcontraindications; the removal may not be

    carried out if there is a serious risk to the lifeor health of the donor;

    - long-term medical follow-up is provided toliving donors. This includes the monitoring ofshort-and long-term effects of organ removalon the health of the living donor notably bythe establishment of officially recognisedregistries.

    2. States Parties to the Convention may requirethat persons waiting for such transplants beplaced on a national waiting list during the periodof approval of the potential donor for donation.

    3. Any States Parties to the Convention allowing fornon-genetically related living kidney donationshould establish a register for such transplantswhich includes a donor register and donorfollow-up procedures in line with those existingfor transplantations of kidneys removed fromgenetically related living donors.

    4. States Parties to the Convention may permit orprohibit by law non-directed living kidneydonations i.e. good Samaritan donors, trulyaltruist donors or donors involved in a pairedexchange donation for the purpose oftransplantation from a person with noestablished close personal relationship with therecipient. (This type of donation is in contrastto donation where the donor and the recipientare in close personal relation called directeddonation). In the States Parties to theConvention authorising donations fromnon-related living donors, national regulationsand appropriate management must be put inplace in view of prohibiting and preventingorgan trafficking, namely by clearly definedrules for non-residents.

    5. States Parties to the Convention should establishan independent mechanism for approvingnon-genetically related living kidney donortransplants in compliance with Article 10 of theAdditional Protocol to the Convention on HumanRights and Biomedicine concerning theTransplantation of Organs and Tissues of HumanOrigin. It is also recommended that StatesParties to the Convention establish such amechanism for all cases of non-directeddonation. Particular attention should be given tocases where the donor is not a resident of themember state concerned. Within therequirements of data protection legislation,registered activities should be reported on aregular basis to the national health authority.

  • 48

  • 49

    www.transplant-observatory.org

  • 50

  • 53

    LIST OF PARTICIPANTS CD-P-TO(15/03/08 - Strasbourg)

    AUSTRIADr. MUEHLBACHER FerdinandBELGIUMDr. COENE LeenBULGARIADr. BRANKOV DimitarCYPRUSCZECH REPUBLICDr. BREZOVSKY PavelDENMARKDr. CARLSEN JornESTONIADr. DMITRIEV PeeterFINLANDDr. SALMELA KaijaFRANCEDr. LOTY BernardDr. LUCIOLLI EsmeraldaGERMANYDr. KIRSTE GnterGREECEDr. GOMPOU AthinaHUNGARYDr. PERNER FerencIRELANDDr. ONEILL FredaITALYDr. NANNI COSTA AlessandroDr. RAGO ClaudioLATVIADr. ROZENTAL RafailLITHUANIALUXEMBOURGDr. MOUSTY RaymondMALTAMOLDOVADr. CONDREANU IgorNETHERLANDSDr. HAASE-KROMWIJK BernadettePOLANDDr. ROWINSKI WojciechPOTUGALDr. PENA Joao RodriguesROMANIADr. ZOTA VictorSLOVENIADr. AVSEC- LETONJA DanicaSPAINDr. MATESANZ RafaelSLOVAK REPUBLICDr. DANNINGER FilipSWEDENDr. WELIN AsaUNITED KINGDOMDr. RUDGE Chris

    (ET) EUROTRANSPLANT

    Austria, Belgium, Croatia, Germany, Luxem-burg, Netherlands, SloveniaDr. RAHMEL Axel(SKT) SCANDIATRANSPLANTDenmark, Finland, Norway, Sweden, IcelandDr. JAKOBSEN Arnt

    ARMENIABELARUSDr. USS AnatolyBOSNIA AND HERZEGOVINACANADADR. AGBANYO FranciscaCROATIAGEORGIADr.TOMADZE GiaICELANDDr. MAGNUSSON SveinnISRAELNORWAYDr. PFEFFER PerRUSSIAN FEDERATIONSERBIADr. GRADINAC SinisaSWITZERLANDDr. MOREL PhilippeTURKEY

    IBEROAMERICAN COUNCILDr. MORALES BELLINI FernandoCOUNCIL OF EUROPEDr. DE SOLA LLERA CarlosDr. GORSETH HallvardDr. LWOFF LaurenceDr. REQUENA MartaDr. SPIESER Jean-Marc (Head of DBO)M-E. BEHR-GROSS (Secretariat)EUROPEAN COMMISSIONDr. FERNANDEZ-ZINCKE EduardoWHODr. NEL Luc