Neurodegeneration Antibodies - Cedarlane Over 135 Antibodies Targeting More Than 310 Neurodegeneration Proteins Neurodegeneration Below is a sampling of select antibodies targeting

Neurodegeneration AntibodiesOver 135 Antibodies Targeting More Than 310 Neurodegeneration Proteins

NeurodegenerationBelow is a sampling of select antibodies targeting proteins for neurodegeneration research. For a complete product listing, please visit: http://www.bethyl.com/category/pca_research_NEUROBIOLOGY.

Target Reactivities Applications # of Abs AbVantage™ Pack

ALS2 / Alsin NEW Hu, Ms WB 1

AP2A1 / Alpha-adaptin NEW Hu WB, IP 1

AP2B1 / Beta-2-adaptin NEW Hu, Ms WB, IP 2 Yes

APTX / Aprataxin Hu WB, IP 1

ATF6 Hu WB, IP, IF, IHC 2 Yes

ATM Hu, Ms WB, IP, IF, IHC, PLA 6 Yes

ATP2A2 / SERCA2 Hu, Rt, Pg, Rb WB, IP 1

ATXN2 / ATX2 / SCA2 Hu, Ms WB, IP 1

BID* Hu, Ms WB, IF, IHC 6 Yes

CHMP2B NEW Hu, Ms WB, IP, IF, IHC 2 Yes

CREB1 / CREB Hu, Ms WB, IP, IF, IHC, PLA 2

CREBBP / CBP Hu WB, IP, IF, IHC, PLA 3 Yes

CTNNB1 / beta-catenin Hu, Ms WB, IP, IF, IHC, PLA 4 Yes

CUL1 Hu, Ms WB, IP, IF, IHC, PLA 2 Yes

DYNC1H1 NEW Hu, Ms WB, IP 1

EIF4G1 / eIF4GI Hu, Ms, Rt WB, IP, IF, IHC 5 Yes

EP300 / p300 HuWB, IP, IF, IHC, ChIP-Seq,

PLA3 Yes

EPRS Hu, Ms WB, IP, IF, IHC 3 Yes

ESR1 / Estrogen Receptor

Alpha*Hu WB, IP, IF, IHC, PLA 5 Yes

FBXW7 / FBW7 Hu IP, IF, IHC 3 Yes

FLVCR1 NEW Hu WB, IP 1

FUS Hu, Ms WB, IP, IF, IHC, PLA 6 Yes

GAPDH Hu, Ms, Rt WB, IF, IHC, PLA 9 Yes

GIGYF2 Hu WB, IP 2 Yes

GSK3B / GSK3-beta Hu, Ms WB, IP, PLA 2 Yes

HDAC1 Hu, Ms WB, IP, IF, IHC, PLA 3 Yes

HDAC2 Hu, Ms WB, IP, IF, IHC, ChIP-Seq 3 Yes

Detection of mouse eIF4G1 in teratoma by

immunohistochemistry. Antibody: Rabbit

anti-eIF4G1/eIF4GI IHC Antibody, Cat#

IHC-00566.

Detection of human and mouse FUS by

western blot of HeLa, Jurkat, and TCMK

cell lysates. Antibody: Rabbit anti-FUS

Antibody, Cat# A300-302A.

About Bethyl Laboratories

Bethyl Laboratories, Inc. is dedicated to improving lives by supporting scientific discovery through its qualified antibody products and custom antibody services. Since its founding in

1972, Bethyl has manufactured all of its antibodies on-site in Texas to exacting standards with validation to a range of

applications.

Select Journal Citations

Target Title Journal

ATM RSF1 Histone-Remodelling Factor Facilitates DNA Double-Strand

Break Repair by Recruiting Centromeric and Fanconi Anaemia

Proteins.

PLoS Biol. 2014 May

6;12(5):e1001856.

BICD2 Distinct Sets of Rab6 Effectors Contribute to ZW10- and COG-

Dependent Golgi Homeostasis.

Traffic. 2014 Feb 27.

FUS Progressive Supranuclear Palsy in a family with TDP-43 pathology. Neurocase. 2014 Jan 30.

FUS Potentiated Hsp104 variants suppress toxicity of diverse

neurodegenerative disease-linked proteins.

Dis Model Mech.

2014 Jul 25. pii:

dmm.016113.

TMEM106B TMEM106B, the Risk Gene for Frontotemporal Dementia, Is

Regulated by the microRNA-132/212 Cluster and Affects

Progranulin Pathways.

J Neurosci. 2012 Aug

15;32(33):11213-27.

All antibodies are antigen affinity purified.*Phospho-specific available

Antibodies


HK1 / Hexokinase 1 NEW Hu, Ms WB 1

HSPB1 / HSP27 NEW Hu WB, IP 2 Yes

KIF1B Hu, Ms WB, IP 2 Yes

KIF5A NEW Hu WB, IP 1

MAPK14 / p38 MAPK Hu, Ms WB, IP 2 Yes

MTMR2 NEW Hu, Ms WB 1

NCSTN / Nicastrin NEW Hu WB, IP 1

NOTCH1 Hu WB, IP, IF, IHC, PLA 3 Yes

OPTN / Optineurin Hu WB, IP 2 Yes

POLR2A / RNA

Polymerase II* NEWHu, Ms WB, IP, IF, IHC, ChIP-PCR, PLA 9 Yes

POLR2B / Rpb2 Hu WB, IP 2 Yes

PPARG /PPAR-gamma NEW Hu, Ms WB, IP 2 Yes

PPARGC1A / PGC-1 Hu IF, IHC 1

PPP2R5D Hu, Ms WB, IP 3 Yes

PPP3CA Hu, Ms WB, IP, IF, IHC 3 Yes

PPP5C Hu, Ms WB, IP, IF, IHC, PLA 2

PSEN2 / Presenilin-2 NEW Hu WB, IP, IF, IHC 1

PSMC5 / TRIP1 / SUG1 Hu, Ms WB, IP, IF, IHC 3 Yes

PSMD11 Hu, Ms WB, IP 2 Yes

PTGS2 / COX-2 Hu WB, IP, IF, IHC 1

RCOR1 / CoREST Hu WB, IF, IHC, PLA 2

REST Hu WB, IP, IF, IHC 3 Yes

SETX / Senataxin Hu WB, IP 2 Yes

SIN3A Hu, Ms WB, IP, IF, IHC 3 Yes

SOD2 / MnSOD Rt WB 2 Yes

SP1 Hu, Ms WB, IP, IF, IHC, PLA 4 Yes

SPTBN2 / SCA5 Hu WB, IP 2 Yes

Detection of human TDP1 by western

blot of immunoprecipitates from HeLa

cell lysate. Antibodies: Rabbit anti-TDP1

Antibody, Cat# A301-618A, used for

immunoprecipitation and western blotting.

TDP1 was also immunoprecipitated by

A301-619A, which recognizes a different

epitope.

Detection of human eEF2 in colon

carcinoma by immunofluorescence.

Antibody: Rabbit anti-eEF2 IHC Antibody,

Cat# IHC-00330.

Detection of human Optineurin by western

blot of immunoprecipitates from HeLa cell

lysate. Antibodies: Rabbit anti-Optineurin

Antibody, Cat# A301-831A, used for

immunoprecipitation and western blotting.

Optineurin was also immunoprecipitated

by A301-829A, which recognizes a

different epitope.




APTX /

Aprataxin

Genotype-phenotype correlations in early onset ataxia with ocular

motor apraxia and hypoalbuminaemia.

Brain. 2011 May;134(Pt

5):1387-99.

TARDBP /

TDP43

Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS

Patients with TDP-43 Mutations.

PLoS One. 2013 Oct

15;8(10):e76055.

TMEM106B TMEM106B expression is reduced in Alzheimer's disease brains. Alzheimers Res Ther.

2014 Mar 31;6(2):17.

VCP Ubiquitin ligase human TRIM71 regulates let-7 microRNA

biogenesis via modulation of Lin28B protein.

Biochim Biophys Acta.

2014 Mar 3. pii: S1874-

9399(14)00045-5.

Neurodegeneration AntibodiesBelow is a sampling of select antibodies targeting proteins for neurodegeneration research. For a complete product listing, please visit: http://www.bethyl.com/category/pca_research_NEUROBIOLOGY.


STUB1 / CHIP Hu, Ms WB, IP, IF, IHC, PLA 3 Yes

TAF1 Hu WB, IP, IF, IHC 2 Yes

TBP Hu WB 1

TDP1 Hu WB, IP, IF, IHC, PLA 3 Yes

TFG Hu, Ms WB, IP 3 Yes

TMEM106B Hu, Ms WB 1

TP53 / p53 Hu WB, IP, IF, IHC, F, PLA 4 Yes

UBA1 / UBE1 Hu, Ms WB, IP, IF, IHC 5 Yes

VAPB Hu, Ms WB, IP, IF, IHC 1

VCP Hu, Ms WB, IP, IF, IHC, PLA 3 Yes

VPS35 NEW Hu, Ms WB, IP 1

Detection of human FUS by western blot of

immunoprecipitates from HeLa cell lysate.

Antibodies: Rabbit anti-FUS Antibody, Cat#

A300-302A, used for immunoprecipitation

and western blotting. FUS was also

immunoprecipitated by a previous lot of

this antibody.

Detection of human PSMD1 in breast

carcinoma by immunohistochemistry.

Antibody: Rabbit anti-PSMD1 Antibody,

Cat# A303-852A.




DAXX Alternative lengthening of telomeres in neuroblastoma cell lines is

associated with a lack of MYCN genomic amplification and with p53

pathway aberrations.

J Neurooncol. 2014

May 3.

GAPDH LPS-induced microglial secretion of TNFa increases activity-

dependent neuronal apoptosis in the neonatalcerebral cortex.

Cereb Cortex. 2013

Jul;23(7):1742-55.

KIF1B Dynamic changes in presynaptic and axonal transport proteins

combined with striatal neuroinflammation precede dopaminergic

neuronal loss in a rat model of AAV alpha-synucleinopathy.

J Neurosci. 2009 Mar

18;29(11):3365-73.

Bethyl Laboratories, Inc. now offers over 3,500 trial-sized antibodies to more than 2,200 protein targets. Since its founding in 1972, Bethyl has manufactured all of its antibodies on-site in Texas to exacting standards with validation to a range of applications.

Trial sizes are conveniently priced and serve as an opportunity to discover for yourself why our antibodies are really good.

Bethyl will be releasing hundreds more trial-sized antibodies in the upcoming months.

Terms & Conditions: See website for US pricing; international customers please contact your distributor for details. Trial-sizes (catalog # ending in “-T”) are not available for all antibodies and existing promotions or discounts do not apply.

Please visit www.bethyl.com/trialsize for a complete list of proteins targets available as a trial size.

Now Available Trial-Size Antibodies!

Detection of human CD44 in

lung carcinoma by immunofluorescence.

Antibodies: Rabbit anti-CD44 Antibody,

Cat# A303-872A. Secondary: Goat

anti-Rabbit IgG (H+L) Antibody, DyLight®

550 Conjugated, Cat# A120-101D3.

Neurodegeneration Antibodies - Cedarlane Over 135 Antibodies Targeting More Than 310 Neurodegeneration Proteins Neurodegeneration Below is a sampling of select antibodies targeting

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