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Blood Ba
Centrifug
Chem
Flow Cyto
Hemat
Hemos
Immunoa
Information Sys
Lab Autom
Molecular Diagno
Rapid Diagno
BR-14342A-OUS
Bringingmoreefficiency and performance
to the hematology lab.
The HematoFlow Cellular Analysis Solution
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Combining our Flow Cytometryand Hematology Technology.
Hematology laboratories, the world over, are being pressured to
improve productivity, decrease turnaround
time (TAT) and reduce costs . You asked and we listened. By
combining our hematology and flow cytometry
technology to characterize abnormal WBC populations, the
hematology laboratory is offered a unique
automated solution. This combination of Beckman Coulter
technologies is known as HematoFlow. Samples
with abnormal WBC results are first identified using one of our
hematology analyzers. Then using our FC
500 Flow Cytometer with CytoDiff, a ready-to-use cocktail,
composed
of six monoclonal antibodies, in five colors, those abnormal
WBC
samples are characterized into nine distinct populations.
Why is this beneficial to the hematology laboratory?
You get all of these advantages:
Lab technologists can focus on other tasks
Automated flow differential
Accurate and standardized results
Simple, paperless process
Precise (>20k cells)
9 cell populations
Auto-verification via decision rules
Faster turnaround time
Surety vs Screening
Manual differentials are performed on an average of 100 to 200
cells. Using the CytoDiff reagent in conjunction
with the Beckman Coulter FC 500 Flow Cytometer, over 20,000
cells can automatically be characterized. Accurate and precise
results
Increased reliability and decreased subjectivity of the data
Provides a differential for even the most difficult cases
(leukopenic samples)
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Standardization
Performing a manual differential can often be time consuming and
subjective. By automating this processwith the CytoDiff reagent,
standardization is now available for hematology labs
everywhere.
Improved Efficiency
The exclusive Beckman Coulter algorithms automatically identify
and enumerate multiple cell populations.This dramatically increases
the reliability of your results, and reduces the need for manual
gating andinterpretation.
Unique Cellular Solutions
The CytoDiff reagent yields an automated 9-part cytometric
differential. It provides the traditional 5-partdifferential with
the addition of immature granulocytes and blasts. Lymphoblasts are
subdivided into T andB cell blasts. Non-T blasts, non-B blasts and
plasma cells are classified into their own category calledother
abnormal cells.
Antibody Cell Population
CD36-FITC Monocytes
CD2-PE T lymphocytes, NK cells
CD294-PE Eosinophils, Basophils, T cells
CD19-ECD B lymphocytes
CD16-PC5 Mature and immature granulocytes, T cytotoxic
lymphocytes
CD45-PC7 Leukocytes
Microscopy
Cell Preparation System
(FP 1000 shown)
Flow Cytometer
(FC 500 Flow Cytometer withAutomated Algorithm)
Hematology Analyzer
(UniCel DxH 800 CoulterCellular Analysis System)
Clinical
Information Systems
(Remisol Advance*/DM2)
Laboratory
Information System
(LIS)
Samples are routinely analyzed on theUniCel DxH 800 or LH 700
SeriesHematology Analyzer.
Normal CBC results are automaticallytransmitted to the
LaboratoryInformation System (LIS) via the datamanager.
Abnormal RBC results areinvestigated by microscope.
For abnormal WBC results, the datamanager automatically requests
areflex CytoDiff test, which promptssample preparation for
CytoDiffanalysis.
The CytoDiff-prepared sample is thenanalyzed on the Beckman
Coulter FC500 Flow Cytometer.
The result is then transmitted to thedata manager and matched to
thepatients original hematology result(s).
Final results are transmitted to thelaboratorys LIS.
HematoFlow Workflow Process
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Scan this QR code with your Smartphone to
watch a video about our HematoFlow CellularAnalysis Solution.
Free QR Code Scanner software
can be downloaded at sites such as www.beetagg.com.
www.beckmancoulter.com/cytodiff
For Beckman Coulters worldwide office locations and phone
numbers, please visit Contact Us at www.beckmancoulter.co
B2010-11559-DG-5K 2011 Beckman Coulter, Inc. PRINTED IN U.S
CytoDiff is not yet available in the US and Canada for in
vitrodiagnostic use. Beckman Coulter, the stylized logo and UniCel
are registered trademarks of Beckman Coulter, Inc. CytoDiff,
HematoFlow and DxH are trademarks of Beckman Coulter, Inc. *REMISOL
Advance is a trademark of Normand Info SAS.