Hazelo Lab Pvt. Ltd. Environmental Impact Assessment Report 6-1 Team Labs and Consultants 6.0 RISK ASSESSMENT AND DAMAGE CONTROL 6.0 Introduction This chapter presents the risk assessment study results for the plant operations, transport and storage of raw materials, and identifies maximum credible accident scenarios to draw the emergency management plan addressing various credible scenarios identified. 6.1. Objectives and Scope The production of Synthetic Organic chemicals (bulk drug and intermediates) involves usage of many chemicals which are both hazardous and toxic in nature. The risks associated with the chemical industry are commensurate with their rapid growth and development. Apart from their utility, chemicals have their own inherent properties and hazards. Some of them can be flammable, explosive, toxic or corrosive etc. The whole lifecycle of a chemical should be considered when assessing its dangers and benefits. In order to ensure the health and safety of persons at or near the facilities, Govt. has approved some regulations. The regulation requires Employers to consult with employees in relation to: - Identification of major hazards and potential major accidents - Risk assessment - Adoption of control measures - Establishment and implementation of a safety management system - Development of the safety report The involvement of the employees in identification of hazards and control measures enhances their awareness of these issues and is critical to the achievement of safe operation in practice. In order to comply with regulatory authorities, M/s Hazelo Lab Pvt. Ltd., have entrusted Team Labs and Consultants, Hyderabad to review and prepare Hazard analysis and Risk assessment for their facility along with an approach to on-site emergency preparedness plan as required under the acts and rules. (Manual on emergency preparedness for chemical hazards, MOEF, New Delhi). In this endeavor, the methodology adopted is based on;
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6.0 RISK ASSESSMENT AND DAMAGE CONTROL 6.0 Introduction
This chapter presents the risk assessment study results for the plant operations, transport
and storage of raw materials, and identifies maximum credible accident scenarios to draw
the emergency management plan addressing various credible scenarios identified.
6.1. Objectives and Scope
The production of Synthetic Organic chemicals (bulk drug and intermediates) involves
usage of many chemicals which are both hazardous and toxic in nature. The risks
associated with the chemical industry are commensurate with their rapid growth and
development. Apart from their utility, chemicals have their own inherent properties and
hazards. Some of them can be flammable, explosive, toxic or corrosive etc. The whole
lifecycle of a chemical should be considered when assessing its dangers and benefits. In
order to ensure the health and safety of persons at or near the facilities, Govt. has
approved some regulations. The regulation requires Employers to consult with employees
in relation to:
- Identification of major hazards and potential major accidents - Risk assessment - Adoption of control measures - Establishment and implementation of a safety management system - Development of the safety report
The involvement of the employees in identification of hazards and control measures
enhances their awareness of these issues and is critical to the achievement of safe
operation in practice. In order to comply with regulatory authorities, M/s Hazelo Lab Pvt.
Ltd., have entrusted Team Labs and Consultants, Hyderabad to review and prepare
Hazard analysis and Risk assessment for their facility along with an approach to on-site
emergency preparedness plan as required under the acts and rules. (Manual on emergency
preparedness for chemical hazards, MOEF, New Delhi). In this endeavor, the
Considering operating modes of the facility, and based on available resources the following
hazard identification process chosen are:
a) Fire Explosion and Toxicity Index (FETI) Approach; b) HAZOP studies; c) Maximum Credible Accident and Consequence Analysis (MCACA); d) Classification of Major Hazard Substances; e) Manufacture Storage and Import of Hazardous Chemical Rules, 1989 (GOI Rules,
1989); f) Identification of Major Hazardous Units.
The physical properties of solvents used in the process are presented in Table 6.2 which
forms the basis for identification of hazards during storage and interpretation of the
Manufacture, Storage and Import of Hazardous Chemical Rules, 1989 (GOI Rules, 1989)
The interpretation of “The Manufacture Storage and Import of Hazardous chemicals”
issued by the Ministry of Environment and Forests, GOI, which guides the preparation of
various reports necessary for safe handling and storage of chemicals shows that the
present project requires preparation of safety reports before commencing operation and
risk assessment is not mandatory. The applicability of various rules is presented in Table
6.4.
Table 6.5 Applicability of GOI Rules to Storage/Pipeline S. No
Chemical Inventory KL
Threshold Quantity (T) For Application of Rules Applicable Rules 5,7-9, 13-15 10-12
Based on the analysis of past accident information, common causes of major chemical
plant accidents are identified as:
• Poor house keeping • Improper use of tools, equipment, facilities • Unsafe or defective equipment facilities • Lack of proper procedures • Improving unsafe procedures • Failure to follow prescribed procedures • Jobs not understood • Lack of awareness of hazards involved • Lack of proper tools, equipment, facilities • Lack of guides and safety devices • Lack of protective equipment and clothing
Failures of Human Systems
An assessment of past chemical accidents reveals human factor to be the cause for over
60% of the accidents while the rest are due to other plant component failures. This
percentage will increase if major accidents alone are considered for analysis. Major
causes of human failures reported are due to:
• Stress induced by poor equipment design, unfavorable environmental conditions, fatigue, etc.
• Lack of training in safety and loss prevention. • Indecision in critical situations. • Inexperienced staff being employed in hazardous situations.
Often, human errors are not analyzed while accident reporting and accident reports only
provide information about equipment or component failures. Hence, a great deal of
uncertainty surrounds analysis of failure of human systems and consequent damages.
The number of persons/materials are potentially exposed to a specific hazard zone is a function of the population density and distribution near the accident location. The failure rate data and ignition sources of major fires are presented in the following Tables 6.8 and 6.9.
Table 6.9 Failure Rate Data
S.No Item International Data 1. Process Controllers 2.4 x 10-5 hr-5 2. Process control valve 2.0 x 10-6 hr-1 3. Alarm 2.3 x 10-5 hr-1 4. Leakage at biggest storage tank 5.0 x 10-5 yr-1 5. Leakage of pipe line 1 x 10-7 m-1 yr-1 6. Human Failure 1 x 10-4 (demand)-1
Full bore rupture 8.8*10-7/m.year Significant leak 8.8*10-6/m.year
>50 mm =150 mm dia
Full bore rupture 2.6*10-7/m.year Significant leak 5.3*10-6/m.year
>150 mm dia
Full bore rupture 8.8*10-8/m.year Significant leak 2.6*10-6/m.year
hose Rapture/Failure 4.0*10-5/hr Unloading arm Rapture/Failure 3.0*10-8/hr Check valve Failure on demand 1.0*10-4/on demand motor operated valve Failure on demand 1.0*10-3/ on demand Flange Leak 3.0*10-4/ Year Pump seal Leak 5.0*10-3/ Year Gasket failure Failure 5.0*10-5/ Year Process safety valve(PSV)
Lifts heavily 4.0*10-3/ Year Blocked 1.0*10-3/ Year Lifts lightly 6.0*10-2/ Year
6.7 Consequence Analysis
The accidental release of hazardous chemicals leads to subsequent events, which actually
1.33 – 2 Severe Lung damage 0.01 Crack of Windows 1 – 11/3 50% Eardrum rupture - -
Source : Marshall, V.C.(1977)’ How lethal are explosives and toxic escapes. 6.7.2 Results of Consequence Analysis
The damages due to the accidental release of chemicals are of three types. a) Damage due to heat radiation b) Damage due to Over pressure effects subsequent to explosion c) Damage due to Toxic effects
LD50 – Median lethal dose The dose at which 50 percent of test animals die following exposure. Dose is usually
expressed as milligrams for kilogram of body weight of test animal. The most popular
way of expressing lethality of toxic loads is to use probit functions.
P = A + B ln (Cn t) where P is probit value, A , B, n – constants specific to the chemical t -- time of exposure in seconds, c – concentration in mg /m 3 or ppm
Knowing the concentration level and time of exposure, the percentage lethality may be
estimated. However for most of the chemicals the characteristic constants are not available
and in such cases IDLH values are used.
The storage of toxic chemicals was evaluated with respect to failure of containment
resulting in toxic dispersion and the toxic damage distances were calculated using
ALOHA software. The results of the same are presented in Table 6.16. Toxic Dispersion
damage distances are shown in Fig 6.6 to 6.7
Table 6.17 Toxic Dispersion Damage Distance S.No Name of Raw
Unsecured Load Relief device failure Driver rest periods Existing accident Tire failure Maintenance Inspection Soft shoulder Overpressure Time of day Restrictions Material defect Steering failure Sloshing High center of gravity Corrosion; Bad Weld; Excessive Grade Poor Intersection design Suspension system
The scenarios presented for storages are calculated for transport related
incidents/accidents and presented in Table 6.19.
Table 6.20 Transportation Specific Concerns Concern Road Spill on Water Over or near a body of water Unconfined Pools In an undisturbed flat area BELVE-Induced catastrophic vessel failure
Possible if sufficient quantity in car with small leak to feed fire or if double tank trailer or burning fuel leak
6.7.7 Control Measures for Accidental Spillage of Chemicals Name of the Chemical Stored
Storage Details Hazard Rating Systems Type of Hazards Involved Persons Effected
Control Measures Quantity
(KL) Pressure/
Temp TLV
(PPM) STEL (PPM)
FP (OC)
Acetone 30 NTP 1000 500 -20 Highly flammable liquid and vapor. Causes serious eye irritation. May cause drowsiness or dizziness.
Operators Maintenance Technicians
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Safety board’s displayed on the tank. Effective ventilation must be provided. For accidental contact if you feel unwell, seek medical advice immediately. Handling of Acetone with Safety gloves and protective clothing
Dimethyl Formamide
30 NTP 10 58 Flammable liquid and vapor Harmful in contact with skin Causes serious eye irritation Harmful if inhaled
Operators Maintenance Technicians
Avoid exposure - obtain special instructions before use. Avoid contact with skin and eyes. Avoid inhalation of vapor or mist. Keep away from sources of ignition - No smoking. Take measures to prevent the buildup of electrostatic charge. Wear respiratory protection. Avoid breathing vapors’, mist or gas. Ensure adequate ventilation.
equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas.
Dichloromethane 20 NTP 50 13 Limited evidence of a carcinogenic effect.
Operators Maintenance Technicians
Do not breathe gas/fumes/vapour/spray. Avoid contact with skin and eyes Wear suitable protective clothing and gloves. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage
Toluene 20 NTP 200 4 Highly flammable liquid and vapor. May be fatal if swallowed and enters airways. Causes skin irritation May cause drowsiness or dizziness. May cause damage to organs through prolonged or repeated exposure
Operators Maintenance Technicians
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. Use personal protective equipment as required. IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. Do NOT induce vomiting. Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation
yet to be determined and the project is still in the initial stages of designing. Hence a
tentative disaster management plan is prepared to be suitably modified before
commissioning of the plant.
6.8.2 Objectives of Emergency Management Plan (ON-SITE) (Terms of Reference No. 7(xiii) A quick and effective response during emergency can have tremendous significance on
whether the situation is controlled with little loss or it turns into a major emergency
Therefore, the objectives of this Onsite Emergency Plan (ONSEP);
During Emergency: Is to provide basic guidance to the personnel for effectively combating
such situations to minimize loss of life, damage to property and loss of property.
• To localize the emergency and if possible eliminate it;
• To minimize the consequences of an emergency;
• To prevent spreading of the damage in other areas;
• To give necessary warning to plant personnel and neighborhood;
• To maximize resource utilization and combined efforts towards the emergency
operations;
• To mobilize internal resources and utilize them in the most effective way;
• To arrange rescue of persons, transport and treatment of causalities; • To seek necessary help from industries in neighborhood or local authorities;
• To provide information to government agencies and to provide information to
public.
During Normal Time:
• To keep the required emergency equipment in stock at right places and ensure their working condition;
• To keep the concerned personnel fully trained in the use of emergency equipment;
• Preserving records, evidence of situation for subsequent emergency etc.
• Special fire fighting information related to Hydrocarbon fuels;
• Public address megaphone, hand bell, Emergency torch.
b) Assembly points
Office room is identified as Assembly point and is in a low intensity fire affected zone.
Additionally the following places in plan are designated as safe assembly points: Time
office, and green belt area near the main road. The locations of assembly points would be
reviewed later.
c) Fire fighting Facilities
The fire fighting facilities which shall be provided are presented in Table 6.20.
Table 6.21 List of Fire Extinguishers S.No Description of Item Quantity
1. DCP 10 kg 80 Nos. 2. Foam 50 ltrs 50 Nos. 3. CO2 22.5 kg 30 Nos. 4. CO2 6.8 kg 25 Nos. 5. ABC Soda Acid 5 kg 40 Nos. 6. ABC Soda Acid 1 kg 40 Nos. 7. Fire Buckets with stand 50 Nos.
d) Location of First aid Boxes
The first aid boxes will be located at the following places: preparation areas,
administrative office, time office, and will be under the charge of security coordinator.
breathing apparatus and fire suit. They should remain in the incident area as
long as he can safely stay there. In spite of the wearing safety protective
equipment if he is unable to stay in the contaminated area, he should leave
immediately.
6.8.7 BASIC ACTION IN EMERGENCIES
Immediate action is the most important factor in emergency control because the first few
seconds count, as fires develop and spread very quickly unless prompt and efficient
action is taken.
• Take immediate steps to stop leakage/fire and raise alarm simultaneously. • Initiate action as per fire organization plan or disaster management plan, based on
gravity of the emergency. • Stop all operations and ensure closure and isolation valves. • All effort must be made to contain leakage/fire. • Saving of human life shall get priority in comparison to stocks/assets. • Plant personnel with specific duties should assemble at the nominated place. • All vehicles except those required for emergency use should be moved away from
the operating area, in an orderly manner by the predetermined route. • Electrical system except for control supplies, utilities, lighting and fire fighting
system should be isolated. • If the feed to the fire cannot be cut off, the fire must be controlled and not
extinguished. • Start water spray system at areas involved or exposed to fire risks to avoid domino
effects. • In case of leakage of chemicals without fire and inability to stop the flow, take all
precautions to avoid source of ignition. • Block all roads in the adjacent area and enlist police support for the purpose if
warranted.
6.8.8 FIRE FIGHTING OPERATIONS
Enlist support of local fire brigade and neighboring industries.
• Fire fighting personnel working in or close to unignited vapor clouds or close to
fire must wear protective clothing and equipment including safety harness and
manned lifeline. They must be protected continuously by water sprays. Water
1.1.1 Construction Phase 1-2 1.1.2 Operation Phase 1-3
2.0 Sources of Pollution from Manufacturing Process 1-3 2.1 Water Pollution 1-4
2.1.1 Process Description and Technical Specification of Effluent Treatment System 1-6 2.2 Air Pollution 1-13
2.2.1 Emissions from Utilities 1-13 2.2.2 Emissions from Process 1-14 2.2.3 Diffuse Emissions 1-18 2.2.4 Fugitive Emissions 1-18 2.2.5 Odor Management 1-18
2.3 Solvent Use and Recycle 1-19 2.4 Solid Waste 1-21 2.5 Noise Pollution 1-22 3.0 Rainwater Harvesting 1-23 4.0 Occupational Safety and Health 1-26 4.1 Medical Check-up 1-27 4.2 Handling of Toxic Chemicals/Materials 1-28 5.0 Prevention, maintenance and operation of Environment Control System 1-29 6.0 House Keeping 1-29 7.0 Socio Economic Environment 1-30 8.0 Transport systems 1-31 9.0 Reduce, Recovery and Reuse 1-32
10.0 Energy Conservation 1-32 11.0 Green Belt Development 1-32 12.0 Corporate Environmental Responsibility 1-35 13.0 Environment Management Cell 1-35 14.0 CREP Guidelines and Compliance 1-37 15.0 Other Management Practices 1-37 16.0 Cost Estimate for Environment Management Plan 1-38
Hazelo Lab Pvt. Ltd., Contents
List of Tables
List of Figures
S.No Description Page. No. 1.1 Total Effluents Generated and Mode of Treatment 1-4 1.2 Process Effluents Quantity and Quality – Product Wise 1-5 1.3 Details of Treatment Facilities 1-7 1.4 Technical Specifications of Effluent Treatment System 1-9 1.5 Technical Specifications of Biological Treatment Plant 1-10 1.6 Emission Details of Pollutants from Stack 1-13 1.7 Technical Specifications of Bag Filters 1-14 1.8 Quantity and Mode of Treatment of Process Emissions 1-15 1.9 Technical Specifications of Two Stage Scrubber 1-17
1.10 Total Solvent Balance – Product Wise after expansion 1-19 1.11 Solid Waste and Mode of Disposal 1-22 1.12 Storm Water Management 1-24 1.13 Frequency of Health Monitoring 1-28 1.14 Corporate Social Responsibilities – Budget (2017-18 to 2021-22) 1-30 1.15 Activity Wise CSR – Budget (2017-18 to 2021-22) – Program 1-31 1.16 Environmental Management Cost estimate 1-38 1.17 Item Wise Tentative Capital Cost Estimate for Environment Management 1-38
S.No Description Page. No. 1.1 Schematic Diagram of Effluent Treatment System 1-8 1.2 Schematic Diagram of Scrubbing System 1-17 1.3 Rain Water Harvesting Schematic Diagram 1-24 1.4 Location of Storm Water Storage Tank 1-25 1.5 Green Belt Development of Hazelo Lab Pvt. Ltd. 1-34 1.6 Organ gram of the Environment Management Cell 1-36
Hazelo Lab Pvt. Ltd. Environment Management Plan
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ENVIRONMENT MANAGEMENT PLAN
1.0 Introduction
Environmental protection is an issue that no organization can neglect and hope to survive.
The by-products of civilization are being dumped upon the environment to a degree that the
environment finds difficult to assimilate. The key to the success of the integrated approach to
pollution prevention and control is the management and operation of the organization.
Effective committed management delivers a successful industry. As total commitment to the
environment, not just for compliance with legal or regulatory compliance will be the essence
of environment management of an industry. Many companies have recognized the benefits
of implementing an effective environmental management system.
Environmental management plan can be effectively implemented to mitigate the pollution
levels by observing the following;
1. Pollution will be prevented or reduced at the source,
2. Pollution that cannot be prevented will be recycled in an environmentally safe manner,
3. Pollution that cannot be prevented or recycled will be treated in environmentally safe
manner, and
4. Disposal and other releases into the environment will be used “only as a last resort”
and will be conducted in an environmentally safe manner.
The management plan is drawn in consultation with the project proponents with reference to
various potential monitored, identified and predicted in the previous chapters. And the
necessary measures to be taken for the mitigation and control of the same presented, various
pollution control measures adopted which are present in the proposed expansion and
measures identified for adoption are discussed in the Environmental Impact Assessment
Report of the same are presented in appendix of the Environmental Impact Assessment
Report. Review of the process is the essential component of Environmental Management M/s.
Hazelo lab Pvt. Ltd. been conducting experiments to optimize the consumption of raw
materials and to increase the purity of the product.
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1.1 Environment Management Plan 1.1.1 Construction Phase As the unit is located near the road, potential of pollution during construction phase due to
transport of construction materials will be less compared to operational stage. However
industry will ensure that pollution potential in the construction phase is at a minimum.
Wherever applicable, detailed procedures will be developed for control of pollution during
project execution phase for expansion. Separate rooms will be provided for labors and
casual workers. The following measures are to be adopted to minimize pollution load during
construction phase.
Site Preparation
During site preparation considerable amount of soil movement is involved due to
excavation and levelling operations. During construction it is necessary to control uplift of
dust during excavation, levelling and transportation by water sprinkling along the
temporary roads and exposed soil areas. The clearing of plants, shrubs and trees will be
kept to a minimum so as to leave sufficient space for erection of mechanical units and for
civil construction.
Sanitation
Considering the standards of hygiene, the workers involved in construction will be provided
temporary toilets, and drinking water. The toilets will be attached to septic tank so as to
minimize the percolation and to control the subsequent impact on the environment. These
facilities will be properly designed and maintained to ensure minimum environmental
impact.
Noise
The site is located in a place where habitation is minimum and at distance of 0.65 Km. Thus
there will be insignificant impact due to noise on the inhabitants. The construction workers
on site will be provided with personal protective equipment like earmuffs whenever for
those who work near noise generating equipment/sources.
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Wastes from Construction Equipment
Construction activity involves a number of operations that utilize equipment like DG sets.
dozers, cranes etc. These equipment are a source of emissions and solid wastes. Proactive
maintenance to mitigate emissions, while the hazardous solid wastes of waste oils and used
batteries are sent to authorized recyclers. Construction debris shall be reused on site as sub
base for road construction. Spillage is avoided and spill control measures are adopted to
minimize contamination of soil and ground water resources. The empty containers of
paints, thinners etc shall be sold to authorized buyers.
1.1.2 Operation Phase
During operation stage the major pollution from the proposed expansion is from liquid
effluents from process, utilities and domestic facilities, and air pollution from utilities and or
combustion of fuels/wastes. The effluent treatment system based on zero liquid discharge
principle, shall convert most of the liquid effluents to solids by way of evaporation of salts
and ETP sludge. The environment management plan is drawn in consultation with the project
authorities, R&D experts of Hazelo Lab Pvt. Ltd., and other technical consultants involved in
preparing the project plan. The management, mitigation and enhancement measures
identified for significant impact sources are presented as follows;
2.0 Sources of Pollution from Manufacturing Process:
The major contributions of pollution from proposed expansion are effluent generation from
process, utilities and domestic sources and gaseous emission from process and utilities. The
water pollution is due to the effluent generated from process, washings, Scrubber, utility
blow downs and domestic sources. Majority of effluents generated will be from process and
it will have considerable amount of COD and TDS load and suspended solids, which has to
be effectively treated. The treatment of effluents, and recovery operations of solvents
generate salts and residues respectively, in addition to residues from process operations,
which are considered hazardous wastes. The air pollution is caused due to combustion of
both fuels and solid/gaseous wastes. The quantities and quality of effluents, emissions and
Hazelo Lab Pvt. Ltd. Environment Management Plan
1-4 Team Labs and Consultants
solid wastes are identified and quantified in the environmental impact assessment study.
The environment management measures proposed are described as follows;
2.1 Water Pollution (Terms of Reference No. 3(vi) & 7(iv))
The effluents generated in the process, separation techniques and during purification
contain organic residues and inorganic raw materials, solvents, and products. Hence the
effluents contain both organic and inorganic salts in various quantities leading to high COD
and TDS levels respectively. Effluents from process, washings, Scrubbing media, and utility
blow downs will be sent to the effluent treatment system. The treated effluent will be
reused for cooling towers makeup and scrubbers. The total effluent generated and mode of
treatment is presented in Table 1.1. The quantity and quality of effluents generated from
process for each product is presented in Table 1.2.
Table 1.1 Total Effluents Generated and Mode of Treatment Description Quantity (KLD) Mode of Treatment
Permitted After Expansion
HTDS Effluents Process 4.52 102.56 Sent to Stripper followed by MEE and ATFD.
Stripper Condensate sent to Cement Plants for Co-Incineration. MEE and ATFD Condensate sent to Biological treatment plant followed by RO. RO rejects sent to MEE and permeate is reused in cooling towers make-up and scrubbers.
Washings 1 10
Scrubber Effluent 10 Sent to MEE followed by AFTD, Biological treatment plant and RO. RO/DM Plant
Rejects 24
Total I 5.52 146.46 LTDS Effluents
Boiler Blow downs 1 10 Sent to Biological Treatment System followed by RO. RO permeate reused for cooling tower makeup and scrubbers. RO rejects sent to MEE.
Cooling Tower Blow downs
0.5 26
Domestic 1 8.5 Total II 2.5 44.5 Grand Total (I+II) 8.02 191.06
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Table 1.2 Process Effluents Quantity and Quality – Product Wise S.No Name of Product Quantity (Kg/day) Concentration
2.1.1 Process Description and Technical Specification of Effluent Treatment System (Terms of Reference No. 7(iv) & Sp. TOR (5)) The Effluent management system is developed to ensure `Zero Liquid Discharge’.
Segregation of effluents is an integral part that facilitates effective treatment of various
effluent streams. The effluents are segregated into two streams; High COD/ TDS and Low
COD/ TDS streams.
The High TDS/ COD Effluents
The treatment system for treating High TDS / COD effluents consists of Equalization,
Neutralization, Settling tank, Stripper, Multiple Effect Evaporator (MEE) followed by
Agitated Thin Film Dryer (ATFD). The organic distillate from the stripper is sent to cement
plants for co-incineration and aqueous bottom from stripper is sent to MEE followed by
ATFD for evaporation. The condensate from the MEE and ATFD are sent to ETP
(Biological). Salts from ATFD are disposed to TSDF.
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The Low TDS/ COD Effluents:
These effluents along with the condensate from MEE and ATFD are treated in primary
treatment consisting of equalization, neutralization, and primary sedimentation followed by
secondary biological treatment consisting of aeration tank and clarifier.
The treated effluents after biological treatment are subjected to tertiary treatment in a reverse
osmosis (Double Stage RO) system. Permeate from RO is reused for cooling tower make-up
and scrubbers while rejects are sent to MEE followed by ATFD. Sludge from various units of
Biological treatment are thickened in sludge handling system and sent to TSDF. Schematic
diagram of effluent treatment system is presented in Fig 1.1. Details of treatment facilities are
presented in Table 1.3. Technical specifications of effluent treatment system are presented in
Table 1.4 and 1.5 respectively.
Table 1.3 Details of Treatment Facilities S.No Facility Description Capacity of Unit (KLD)
Table 1.4 Technical Specifications of Effluent Treatment System S.No Description Unit After
Expansion Stripper
1 Design Capacity KLD 135 2 Feed Rate Kg/hr 4000-6000 3 Specific Gravity of Feed ≈ 1.03 4 Initial Feed COD PPM 20000-50000 5 Feed Total Solid % 2.0-4.0 6 High Heating Temperature OC 95 – 100 7 High COD Condensate recovery LPH 150-200 8 Dry Saturated Steam requirement at 3.0Kg/cm2 (g) TPH 0.8-1.2 9 Cooling Water circulation rate for condenser m3/hr 1.2-2.5 10 Cooling Water Inlet Temperature OC 30 – 32 11 Cooling Water Outlet Temperature OC 38 – 40
Multiple Effect Evaporator (MEE) 1 Design Capacity KLD 200 2 Feed Rate Kg/hr 7000-9000 3 Feed Concentration mg/l 30000-70000 4 Feed Temperature OC 30 5 Initial Solids % 5.0-8.0 6 Solids in Concentrate % 35.0-40.0 7 Concentrate Output Kg/hr 1500-2500 8 Water Evaporation Rate Kg/hr 5000-8000 9 Designed Water Evaporation Rate Kg/hr 6000 10 Dry Saturated Steam requirement at 6.0Kg/cm2 (g) TPH 3.0-4.0 11 Cooling Water Circulation Rate at 30 – 32OC m3/hr 10.0-15.0 12 Cooling Water Inlet Temperature OC 30 – 32 13 Cooling Water Outlet Temperature OC 38 – 40
Agitated Thin Film Dryer (ATFD) 1 Designed Capacity KLD 50 2 Feed Rate Kg/hr 1500-2500 3 Initial Feed Solid Content % 35.0-40.0 4 Final Moisture in Dry Bag-gable Product % 2.0-3.0 5 Water Evaporation Rate Kg/hr 1000-1500 6 Designed Water Evaporation Kg/hr 1200 7 Solid Output in Bag-gable form at 5 – 6% moisture Kg/hr 600-800 8 Dry Saturated Steam requirement at 6.0Kg/cm2 (g) Kg/hr 100-150 9 Cooling Water Circulation Rate at 30 – 32OC m3/hr 0.1-0.2 10 Cooling Water Inlet Temperature OC 30 – 32 11 Cooling Water Outlet Temperature OC 38 – 40
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Table 1.5 Technical Specifications of Biological Treatment Plant Data After Expansion Flow from MEE + ATFD : 146.5 KLD Boiler Blow down : 10.0 KLD Cooling Tower Blow down : 26.0 KLD Domestic : 8.5 KLD Total Flow to Neutralization tank : 191 KLD Design Capacity : 250 m3/day Flow : 191 m3/day BOD : 458 mg/l COD : 4589 mg/l Total Dissolved Solids : 513 mg/l BOD load : 88.5 kg/day COD load : 877 kg/day Total Dissolved Solids : 98 kg/day Neutralization Tank Average flow : 20.2 m3/hr Hydraulic retention time : 12 hrs. at peak flow Volume : 250 m3 Tank : 2 no. Proposed based on Daily flow. Aeration Tank - 1 BOD(yo) : 458 mg/l % of BOD removed : 80 BOD Load : 17.7 kg/day COD : 4589 mg/l COD Load : 877 kg/day Outlet BOD : 97 mg/l MLSS : 6000 mg/l F/M ratio : 0.18 Flow : 250 m3/day Volume of the Tank : 191 m3 Check for Detention time : 22.6 Hours (12 - 24) Assuming depth : 3.5 m (4.0+0.5 F.B) Area of the tank : 67.13 m2 Width of the tank : 8.19 m Length of the Tank : 4.10 m BOD5 load in the aeration tank : 206.37 Oxygen is required for every Kg of BOD5 to be removed
: 2.00 kgs
Oxygen requirement for areation : 412.74 kg/day O2 in Air % : 0.21 % Density of Air : 1.20 Oxygen requirement : 50.00 m3/kg O2/day Air Required : 20635.6 m3/day
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: 502.2 cfm Consider 35% excess considering the air required in the equalization tank. Total air required : 684.52 Kg O2/day Clarifier - 1 Design quantity : 250 m3/m2-day Surface loading rate of average flow : 12 m2 Surface area provided : 20.8 m length of the tank (2l=b) : 4.56 m (Say 4.5 m) Width of the tank : 2.28 m (Say 2.5 m) Aeration Tank - 2 BOD(yo) : 144 mg/l % of BOD removed : 80 BOD Load : 29.3 kg/day COD : 288 mg/l COD Load : 59 kg/day Outlet BOD : 29 mg/l MLSS : 5500 mg/l F/M ratio : 0.18 Flow : 250 m3/day Volume of the Tank : 227.3 m3 Check for Detention time : 21.8 Hours (12 - 24) Assuming depth : 3.5 m (4.5+0.6 F.B) Area of the tank : 64.94 m2 Width of the tank : 8.06 m Length of the Tank : 4.03 m BOD5 load in the aeration tank : 29.25 Oxygen is required for every Kg of BOD5 to be removed
: 2.00 kgs
Oxygen requirement for aeration : 58.51 kg/day O2 in Air % : 0.21 % Density of Air : 1.20 Oxygen requirement : 50.00 m3/kg O2/day Air Required : 2925.29 m3/day : 71.87 cfm Consider 35% excess considering the air required in the equalization tank. Total air required : 97.03 Kg O2/day Clarifier - 2 Design quantity : 250 m3/m2-day Surface loading rate of average flow : 12 m2 Surface area provided : 20.8 m length of the tank (2l=b) : 4.56 m (Say 4.5 m) Width of the tank : 2.28 m (Say 2.5 m)
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Holding tank The flow from the each individual settling tank i.e., the supernatant liquid is let into the respective Pre-Filtration Tank, which has a minimum 8 hours holding capacity. This tank is provided to hold the treated effluent and give an even flow to the pressure sand filter. Average flow : 20.8 m3/hr Peak factor : 2 m3/hr Peak flow : 41.7 m3/hr Provide min 1.5 hours holding capacity. Hence required volume of the tank : 62.5 m3 Pressure Sand Filter: Vertical down flow type with graded/sand bed under drain plate with polysterene strains. Flow : 250 m3/day Rate of filtration assumed as : 15 m3/m2/hr Requirement of treated water for usage in 20 hrs : 12.5 m3/hr Dia of filter of 1 nos. : 1030.33 mm Provide a Pressure Sand filter of 1100 mm say 1250 mm dia with sand as media over layer, under drain pipe, laterals face piping etc., Activated Carbon Filter: Vertical down flow type with graded/sand bed under drain plate with polysterene strains. Flow : 250 m3/day Rate of filtration assumed as : 15 m3/m2/hr Requirement of treated water for usage in 20 hrs : 12.5 m3/hr Dia of filter of 1 nos. : 1030.33 mm Provide activated carbon filter of 1100 mm say 1250 mm dia with sand as media over layer, under drain pipe, laterals face piping etc., Reverse Osmosis -1: Design Capacity : 250 KLD Operating capacity : 191 KLD Recovery : 70% RO Permeate : 133.7 KLD RO rejects : 57.3 KLD Reverse Osmosis - 2: Design Capacity : 70 KLD Operating capacity : 57.3 KLD Recovery : 70% RO Permeate : 40.11 KLD RO rejects : 17.19 KLD
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2.2 Air Pollution (Terms of Reference No. 3(vi))
The manufacturing process consists of reaction, separation and purification. The reaction is
conducted in closed reactors, while the separation is conducted in centrifuge, filtration
equipment etc. Purification would be conducted in reactors or filtration equipment. The
transfer of materials will be through closed pipelines. Various sources of emissions are
identified from process operations. The usage of boiler for steam generation and DG sets
for emergency power back up also releases emissions.
2.2.1 Emissions from Utilities (Terms of Reference No. 7(v)
The sources of air pollution are from proposed 2 x 10 TPH coal fired boiler, existing 1 x 2
TPH and existing 1 Lakh K.Cal thermic fluid heater. Backup DG sets of 2 x 1000 KVA are
proposed in addition to existing DG sets of 1 x 250 KVA capacity to cater energy
requirement during load shut downs. Bag filter will be provided as air pollution control
equipment for 2 x 10 TPH coal fired boilers. DG sets shall be provided with effectivestack
height based on the CPCB formula. The emission rates of SO2, NOx and SPM from each
stack are presented in Table 1.6. Technical specifications of Bag filters presented in Tables
1.7
Table 1.6 Emission Details of Pollutants from Stack S.
2 2X1000KVA DG set 10 0.2 180 8 0.01 0.02 0.03 *DG sets will be used during load shut down by TSPDCL.
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Table 1.7 Technical Specifications of Bag Filters S.No Application Unit Value/Description
1 Boiler Capacity TPH 10 Fuel Coal
2 Gas Volume m3/hr@170 degC 28000 Gas Temperature Deg C 180 Outlet emission mg/Nm3 <50 Flange to flange pr. drop mmWC 140 Moisture Content % 8.7 No. of Bags 268 Filter area per bag m² 1.72 Total filter area m² 460 Air to cloth ratio m³/min/m² 1.15
3 Bags Diameter ID, mm 160 Length mm 3650 Material Nomex Max. operating temp. degC 190
4 Bag Cleaning Compressed air required Nm3/Hr 5-7 kg/cm2 No. pulse cum solenoid valve 10 Size of pulse valve NB 40
5 Material of Construction Casing MS
a Tube Sheet MS Cage MS Hopper MS
7 Terminal Points Dirty air Inlet of Poppet Valve, Flanged end Clean air Outlet of Bag Filter, Flanged end Dust discharge RALV Compressed air Inlet of Air Header Electricals Power Supply for Timer 230 V Ac
2.2.2 Emissions from Process
The source of process emissions are reactors, where gaseous products are released, or excess
gaseous raw material used in production, which mainly contain inorganic gases. The other
emissions from process operations and effluent treatment system are mainly known as
diffuse emissions containing dusts, fumes and volatile organic compounds. The VOCs from
among the diffuse emissions are the main cause of odour in the plant area and its
neighborhood. Spillage, leakage and accidental releases are the causes of fugitive emissions,
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releasing solids, liquids and fumes of volatile organic compounds resulting in soil and
ground water contamination in addition to odour in the plant area.
a. Process Emissions: The process emissions contain Ammonia, Carbon dioxide, carbon
monoxide, Hydrogen, Hydrogen Bromide, Bromine, Hydrogen Chloride and Sulfur
dioxide. Ammonia, Hydrogen chloride, Hydrogen Bromide, Bromine and Sulphur dioxide
are sent to scrubber in series. Ammonium Chloride from ammonia scrubbing, Sodium
chloride from HCl scrubbing, Sodium bromide from HBr and Bromine Scrubbing and
Sodium Bisulfite from Sulphur dioxide Scrubbing are sent to ETP. The other gases Carbon
dioxide and carbon monoxide are let out into atmosphere following a standard operating
procedure, while Hydrogen gas is let out into atmosphere through a water column.. The
quantity of process emissions is presented in Table 1.8. Schematic diagram of Scrubbing
system is presented in Fig 1.3. Techncial Specifications of two stage scrubber is presented in
Table 1.9
Table 1.8 Quantity and Mode of Treatment of Process Emissions Product Name Stage Name of Gas Quantity
(Kg/Day) Mode of treatment
Bupropion I
Hydrogen Bromide 529.8 To Scrubber Hydrogen Chloride 14.3 To Scrubber
Desvelofloxin I
Carbon dioxide 41.8 Let out into atmosphere Hydrogen 0.2 Let out into atmosphere
through water column Divolproex sodium I Carbon dioxide 176.8 Let out into atmosphere Esomeprazole Mg I
Hydrogen Chloride 60.1 To Scrubber Hydrogen 0.2 Let out into atmosphere
through water column Rosuvastatin I Hydrogen 1.6 Sertraline Hcl I Hydrogen 5.8 Valaciclovir II Hydrogen 1.2 N2-(1-(S)-ethoxycarbonyl-3-phenylpropyl-N6-trifluoro acetyl)-L-Lysine
Sulfur dioxide 62.2 To Scrubber Hydrogen chloride 35.5 To Scrubber
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Fig 1.2 Schematic Diagram of Scrubbing System
Table 1.9 Technical Specifications of Two Stage Scrubber
Type Packed Tower Scrubber Two Stage MOC PP/FRP 5 mm PP+8mm FRP Air Flow Rate 2500CFM Inlet Temp. 350C Inlet Gas Pressure Atmospheric Batch 24 Hrs Scrubbing medium for IstStage Water 10% NaOH Solution Scrubbing medium for IIndStage Caustic Solution (or) Acid Blower MOC PPFRP Capacity 2500CFM Suction Pressure − 250mmWC Discharge Pressure 60mmWC HP/RPM 5HP/1900RPM Circulation System Flow Rate 15 M3/hr Head 30 Meters Motor Make FLP MOC PP Make Antico Storage/ Recirculation Tank Capacity 3 KL Size 1700mm Dia X 2300mm Ht. MOC PP/FRP
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2.2.3 Diffuse Emissions
Emissions are also released from various operations of manufacturing like centrifuge,
drying, distillation, extraction etc.. These emissions mainly contain volatile contents of the
material sent for processing. The emissions are normally passed through vent scrubber
before releasing into atmosphere to mitigate odour. The emissions from distillation are
passed through condensers, which mitigate odour. It is proposed to provide vent
condensers in series to reactors, distillation columns, driers and centrifuge etc. to mitigate
VOC emissions release. Other vents are connected to common headers and scrubbers. The
transfer pumps shall be provided with mechanical seals. The transfer of solvents shall be
mainly by closed pipeline systems, while drum transfer is by using air operated diaphragm
pumps in closed hoods. The charging of solid raw materials shall be by using closed
hoppers to avoid dust emissions and hazard of static electricity. Breather valves shall be
provided to storage tanks. Thermal insulation and condensers will be provided for storage
tanks of low boiling point solvents. The reactor or solvent storage tank vents when not use
shall be kept closed.
2.2.4 Fugitive Emissions (Terms of Reference No. 7(vi)
Fugitive emissions are anticipated from equipment leakage and transfer spills. The periodic
maintenance program shall ensure integrity of equipment mitigating the equipment
leakage. The spills however shall be managed by adopting the spill management scheme as
mentioned in the respective MSDS, spill control kit shall be provided in storage, and
production blocks. The fugitive emissions shall be reduced by closed transfer and handling
of all hazardous solvents and chemicals. The ventilation system provided will reduce health
impact on the employees by way of dilution of work room air and also dispersion of
contaminated air.
2.2.5 Odour Management (Terms of Reference No. Sp. TOR (6))
Odour is caused mainly by diffuse and fugitive emissions of low boiling organic chemicals/
compounds releasing volatile organic compounds. The above mentioned measures for
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mitigation and control of diffuse and fugitive emissions shall reduce release of VOC’s into
atmosphere and the resultant odour.
2.3 Solvent Use and Recycle
Solvents are used for extraction of products and as reaction medium. Solvents constitute
major consumable material of synthetic organic chemical manufacturing, mainly used as
reaction medium. The used solvents constitute major waste stream of synthetic organic
chemical manufacturing. Hence it is proposed to recycle the solvents by distillation for reuse
in process, thereby reducing total solvent consumption in the plant and reducing the waste
quantity to be disposed. The distillation columns are mainly provided to remove moisture and
impurities from spent single solvents, and mixed solvents. The recycled single solvents are
reused in the process, while the mixed solvents are sold to end users. Distillation process
generates residues which are mainly organic in nature containing significant calorific value,
and can be sent to cement plants for co-incineration as fuel. The total solvent balance product
wise and stage wise is presented in Table 1.10.
Table 1.10 Total Solvent Balance – Product Wise after expansion
2.4 Solid Waste (Terms of Reference No. 3(vi) & 7(vii))
Solid wastes are generated from process, solvent distillation, wastewater treatment and
utilities. Process residue contains mainly unreacted raw materials and byproducts. These are
collected from the reactors and other process equipment and stored in drums. Solvent residue
is generated from distillation units, the residues are tarry substances with good calorific
value, and are stored in drums. The other major waste is salts from multiple effect evaporator
and agitated thin film dryer section of effluent treatment system. These salts are stored in
HDPE lined bags. All solid waste storage containers/drums/bags are labeled showing the
source, nature of hazard and type of wastes. All the hazardous wastes are stored in a closed
shed with fire safety measures, and the shed is provided with a leachate collection facility
connected to effluent conveyance lines. The stripper distillate, process residue and solvent
residue are sent to cement plants for co-incineration based on acceptability. If these wastes
are not suitable for co-incineration, the same is sent to TSDF facility. Mixed solvents shall be
sent to authorized recyclers /cement plant for co-incineration while spent solvents are
recovered within plant premises. The evaporation salts are sent to TSDF. Filter media,
activated carbon and catalysts are sent to TSDF. Waste oil and used batteries from the DG
sets are sent to authorized recyclers. The sludge from effluent treatment plant is considered
hazardous and the same is sent to TSDF. The other solid wastes expected from the unit are
containers, empty drums which are returned to the product seller or sold to authorize buyers
after detoxification. The quantity and disposal plan for the solid wastes is presented in Table
1.11.
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Table 1.11 Solid Waste and Mode of Disposal S.No Description Units Quantity Mode of
Treatment/Disposal Permitted After Expansion
1 Solvent residue TPD 0.033 3.58 Sent to TDSF/Cement Plants for Co-incineration 2 Process Organic
residue TPD 9.12
3 Stripper Distillate KLD 3.4 4 Spent Carbon Kg/day 33.33 368 5 Spent Solvents KLD 1 126.4 Recovered within the
plant premises. 6 Spent Mixed Solvents KLD 0.66 14 Sent to authorized
recovery units/Cement plants for co-incineration
7 Inorganic residue TPD 3.77 Sent to TSDF 8 Hyflow Kg/day 78 9 Catalyst Kg/day 200 10 Evaporation salts TPD 1.33 11.92 11 ETP Sludge TPD 0.65 12 Ash from Boiler TPD 40 Sold to Brick manufactures 13 Detoxified containers No.s/
month 50 650 Sold to authorized
vendors 14 Waste oil KLPA 5.88 Sent to Authorized
Recyclers 15 Used batteries No.s/Yr 20
2.5 Noise Pollution
Noise is anticipated from motors, compressors and DG set. The DG shall be kept in a
separate enclosed room with acoustic enclosure. The motors and compressors shall be
provided with guards and shall be mounted adequately to ensure the reduction of noise and
vibration. The employees working in noise generating areas shall be provided with
earmuffs. The employees shall be trained in the mitigation measures and personal
protection measures to be taken to avoid noise related health impacts.
Measures to Control Noise Pollution
An effective hearing conservation program will be undertaken where exposure to industrial
noise is capable of producing hearing loss. The objective is to ensure that an employee
hearing is not affected during his working life to an extent greater than that usually
occurring with age and to preserve it at a level sufficient for normal speed perception.
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The following engineering control aspects are identified for further implementation to
reduce noise levels/exposure;
• The noise generating sources like motors and compressors will be provided with
Casings and guard to reduce the noise levels
• Placing attenuating screens between the operators and the sources.
• Adequate spacing between noise sources and operators will be provided. In free field
conditions the sound levels roughly varies with the square of the distance.
• Reflected noise is reduced by use of absorbent materials on roofs, walls and floors.
• By proper maintenance, which corrects vibrations and other imbalances, will be taken
up.
• Necessary vibration mitigation measures to ensure least impact on structures and
workmen.
• Personal protective equipment: ear plugs and muffs consisting of fine glass wool, ear
muffs consisting of ear cups with a soft seal, fitted with a spring or adjustable
headband. Comfort, maintenance and cleaning are important aspects of use.
• Plantation of tall as well as short trees around the plant area will protect the outside
environment from any noise and dust nuisance.
• It is possible to reduce the noise levels by 3-5 dB (A) per 30-m width of the green belt.
3.0 Rainwater Harvesting (Terms of Reference No. 7(x)
Rain water harvesting shall be adopted by providing rain water harvesting structures along
the drains, storm water storage sump and tanks. Storm water drains are provided with rain
water harvesting structures which will act as flow dissipaters and also as infiltration
trenches. Filtration points shall ensure percolation of water and enhance the ground water
table. The site area will be provided with 25 nos. of rain water harvesting structures. The
roof water shall be collected in 200 KL capacity sump connected to down spouts of the roofs,
and the collected water shall be reused for process and green belt development. The storm
water from open areas, and green belt area, and the overflow of the roof water storage sump
shall be collected in a storm water storage tank in southeast part of the site and reused for
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plant and process. The storage pond shall have a capacity of 3000 m3. These measures shall
ensure reuse of stored storm water for about 57 days of plant operation expansion. The
storm water is quantified using rational formula, for a rainfall intensity of 854.6 mm, with
constant of 0.5 for open area and 0.3 for green belt area. The total water that can be stored is
in the order of 17205 m3/year. The storage tank and the sump shall get refilled during
intense rain fall periods, and the stored water shall be reused mainly during monsoon and
post monsoon seasons. The location of storm water storage tank, roof water storage sump is
presented in Fig. 1.5 and storm water management is presented in Table 1.12. The
schematic diagram for rain water harvesting structure is presented in Fig 1.5.
Fig 1.3 Rain Water Harvesting Schematic Diagram
Table 1.12 Storm Water Management Land Use Area
in Ha Vol./hr after development
C=0.8 (KL)
Vol./hr before development
C=0.6 (KL)
Difference in Discharges (KL)
Roof Area 2.72 871.8 653.8 217.9 Road Area 4.09 1307.7 980.8 326.9 Open Area 6.81 817.3 1634.6 -817.3 TOTAL 13.62 -272.43 *C=0.3 after development of greenery Area of Catchment, ‘A’ 13.42 Ha Run off Coefficient, ‘C’ 0.5 Maximum intensity of rainfall, ‘I’ 854.6 mm/year Therefore Q 57351 m3/year Storm water Storage (30% run off) 17205 m3/year Water requirement 300.73 KLD No of days usage (Storm water) 57 Storm water storage pond 2000 m2 Storm water storage pond Depth 1.5 m
Total Storm water storage pond Capacity 3000 m3
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S C A LE 1C m = 00 m trs
P RO D U C TIO N BL O C K4 0.0x 12.5
PR O PO SED B LO CK4 0.0x 19.0
40.0x 12 .5
8 .0X 1 2.5MR O A D 5 .0 M
D CPRO P O SED
1 4.0 X 12.5MT A N K S
R O A D 5.0 M
R O A D 7 .0 M
SO LV EN T Y A R D4 5.3x60 .0
L RM -II
4 0.0x 20.0
U N LO A D IN G
P RO P O SE D B LO C K4 0.0x 19.0
IN TER M E D IA T E STO RA G E
Q C& Q A
PRO PO SED
7 0.0x19 .0
PR O PO SED SER V IC E B L O CK7 0.0x12 .5
R O A D 5 .0 M
40.0x 20 .0
2 8.0x20 .0
4 0.0x20 .0
7 0.0x 20 .0
R O A D 5 .0 M
4 0.0x 20 .0
4 0.0x20 .0
7 0.0x 20 .0
R O A D 5.0 M 2 5.0x 12 .5B O ILER2 0.0x12 .5
C O A L SH ED
P RO PO SE D B LO C KPR O PO SED B LO CK
W A RE H O U SE-I
L RM -I
5 0.0x20 .0
4 0.0x 20 .0
W A R EH O U SE-II
C A N TE EN &C H A N G E RO O M S
PR O PO S E D B LO CK
PR O PO SE D PILO T PLA N T
1 0.0x 10.0
T EM PLE
FU T U R E
FU T U R E
FU T U R E
Z LD System
FU T U R E FU T U R E
FU T U R EFU T U R E
FU T U R E
S TO R M W A TERPO N D
Fig 1.4 Location of Storm Water Storage Tank
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4.0 Occupational Safety and Health (Terms of Reference No. 8(iii)
Many worker health and safety hazards are posed by synthesis operations. They include
safety hazards from moving machine parts, pressurized equipment and pipes, heavy
manual handling of materials and equipment, steam, hot liquids, heated surfaces and hot
workplace environments, confined spaces and hazardous energy sources (e.g., electricity);
and high noise levels.
Acute and chronic health risks may result from worker exposures to hazardous chemicals
during synthesis operations. Chemicals with acute health effects can damage the eyes and
skin, be corrosive or irritating to body tissues, cause sensitization or allergic reactions or
be asphyxiants, causing suffocation or oxygen deficiency. Chemicals with chronic health
effects may cause cancer, or damage the liver, kidneys or lungs or affect the nervous,
endocrine, reproductive or other organ systems. Worker exposure to chemicals can occur
during manufacturing when chemicals spill, leak, or discharge from the process system and
contaminate areas where workers are present. The most frequently reported industrial
exposure occurs during the transfer of materials. The entry of workers into systems,
equipment, or enclosures that are contaminated may occur inadvertently, but routine
servicing, nonscheduled maintenance, and process monitoring appear to be the kind of
activities with potential for significant exposure. Health and safety hazards may be
controlled by implementing appropriate control measures (e.g., process modifications,
engineering controls, administrative practices, personal and respiratory protective
equipment).
The process modification shall be a constant exercise of the Research and development wing
of the organization, resulting in reduced pollution loads, and increased yields. The measures
proposed are selection of alternative solvents/routes of synthesis, avoidance of hazardous
chemicals usage, and application of green chemistry principles.
The engineering controls for reducing occupational hazards are provision of scrubbers,
condenser systems for process equipment, piping systems, insulation to reactors, usage of
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transfer pumps with mechanical seals, AOD pumps, trolleys for transfer of drums or bags,
closed hoods for charging raw materials, dip pipe provision for solvent and liquid raw
material charging, level indicators, pressure and temperature indicators, barrier guards on
moving machine parts, optimization of chemical inventory, control switches and emergency
stop devices to mitigate and avoid physical, chemical, electrical and mechanical hazards.
Work practices proposed for improving occupational safety are induction training programs,
safety training programs, rotation of workers, implementation of proactive maintenance
schedule, provision of standard operating procedures for all plant operations, access to
MSDS for all employees, access to emergency numbers of contact, and avoidance of crowded
work place, and provision of occupational safety centre.
Personal protective equipment shall be provided to all the employees including contract
employees. All the employees shall be provided with gumshoe, helmet, masks, and goggles.
The other equipment like ear muffs, gloves, respirators, aprons etc., will be provided to
employees depending on the work area allocated to them. The PPE selection shall strictly
follow the prescribed guidelines of MSDS. The budget allocated for personal protective
equipment is Rs. 60 lakhs and Rs. 20 lakhs for health checkup.
4.1 Medical Check-up (Terms of Reference No. 8(ii)
M/s Hazelo Lab Pvt. Ltd., has a medical program of pre employment screening, periodic
medical examination, emergency treatment, non emergency treatment, and record keeping
and review. The pre employment screening and periodic medical examination shall follow
the guidelines of factories act. The pre employment screening shall obtain medical history,
occupational history followed by physical examination and baseline monitoring for specific
exposures. The frequency of periodic medical examination and type of evaluation is
presented in Table 1.13.
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Table 1.13 Frequency of Health Monitoring
Occupation Type of evaluation Frequency Process area Dermatology examination, ophthalmic examination,
ENT examination, physical examination, complete blood picture, complete urine examination, ECG, Random blood sugar, Lipid profile, Liver function test, kidney function test, Anemia profile, thyroid stimulating hormone, abdomen ultra sound scanning, thread mill test, Spirometry test.
Once a year for regular employees. Half yearly for contract employees
Noise prone areas
Audiometry Annually
The plant shall have an occupational health centre to provide emergency and non emergency
treatment, by way of emergency first aid on site, liaison with local hospitals and specialists,
arranging decontamination of victims, arranging transport of victims to hospitals, and to
transfer medical records, and to provide details of incident and medical history to next care
provider. The occupational health centre shall be supervised by a qualified physician. The
occupational health centre shall maintain the health records and shall analyse the records for
any common symptoms and common health problems which may be due to exposure to
chemicals, and or due to other occupational hazards.
4.2 Handling of Toxic Chemicals/Materials
The engineering controls proposed for reducing occupational hazards in handling of toxic
chemicals are as follows;
Separate Storage area with environmental controls Dispensing of material in isolated dispensing booth with cross ventilation
Transfer of toxic powders by Power Transfer System (PTS)
Level Indicators, sensors, pressure & Temperature indicators provision to reactors
Transfer by dedicated pipe line
Dump tank system in case of overflow
Transfer by using AOD pumps in case of Drum transfer
Vents connected to common scrubbers.
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Administration Controls for handling of toxic chemicals are as follows;
All chemicals are stored based on respective MSDS
Periodic health check-up tuned to Toxic chemicals handled.
All employees are provided with respiratory protection ranging from nose mask to full
body suit to prevent toxic chemicals impacting respiratory system of employees.
Personal Protective Equipment (PPE) based on requirement and suitability.
5.0 Prevention, maintenance and operation of Environment Control System
The pollution control equipment, and the effluent treatment systems and effluents will be
monitored periodically and will be checked for its performance and pro-active maintenance
will be adopted. The environmental monitoring results will be evaluated to identify the
problems/under performance of the equipment. Necessary steps will be taken to rectify the
identified problems/defects. The management agrees that the evaluation of the performance
of pollution control measures and occupational safety measures to arrive at their efficiency
and proposes to adopt new measures for efficient pollution control which will be a regular
exercise.
All pollution control equipments are adequately designed and operating staff of the
pollution control equipment have good experience in the operation and maintenance of the
equipment. Standby equipment provided for all critical equipment to ensure continuous
operation of pollution control equipment and preventive maintenance is done as per the
schedule to avoid breakdown. Characteristics of influent and effluent are monitored on daily
basis by the industry and air emissions and effluent characteristics on monthly basis by third
party.
6.0 House Keeping
Good house-keeping practices will be adopted. Floor washing is avoided and wet mopping
will be adopted to minimize liquid waste generation. Paper waste is minimized by adopting
intra office network. Sufficient workspace and proper lighting will be provided.
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7.0 Socio Economic Environment (Terms of Reference No. 11(i)
The expansion of project provides an opportunity for the local people to get employment
directly or indirectly and helps in the up liftment of the socioeconomic status of the area. The
project proponents propose to involve in social activities of the stakeholders/surrounding
community by planning the betterment of neighbouring social conditions through awareness
and welfare programs will ensure an improved relation, useful in the long run. Many of the
beneficiaries of such programs shall include own employees as well. The goodwill of the
local populace can never be ignored. Another important facet of social environment
identified by the project proponents is a green appearance, hence the management will
develop a green belt towards aesthetic beautification as the same is necessary to be
considered as a responsible, social neighbour. The budget allocated for funding corporate
social responsibility activity is Rs. 112.5 lakhs or 2.5% of the capital cost to be spent during
the first 5 years of the project. The development programs are identified from schedule VII
of companies act 2013. A tentative list of development programs to be adopted as part of
CSR activity, with approximate budget allocation is presented in Table 1.15. The expenditure
shall be mainly towards gender development, skill development, and provision of
infrastructural facilities for drinking water, education and health. The programs identified by
the management as part of corporate social responsibility program are presented in Table
1.14.
Table 1.14 Corporate Social Responsibilities – Budget (2017-18 to 2021-22) S.
No Description TOTAL COST (Rs. IN LAKHS)
2017-18 2018-19 2019-20 2020-21 2021-22 1 Skill Development Training Programme 5 5 5 6 6 2 Drinking Water Facility 6.5 6.5 6 5 5 3 Health Camps 6.5 6 6 5 5 4 Education 5 5 5 6.5 6.5 Total (Rs. Lakhs) 23 22.5 22 22.5 22.5
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Table 1.15 Activity Wise CSR – Budget (2017-18 to 2021-22) – Program S.
No Description TOTAL COST (Rs. IN LAKHS)
2017-18 2018-19 2019-20 2020-21 2021-22 1 Socio-economic Development &
Enriching Livelihood 8.5
8.5
8.5
9
9
Includes activities relating to income generation like skill development programs, Roads, Drinking water facility, sanitation to nearby villages.
2 Value addition and necessary improvements in Government Schools
6 6 6 6.5 6.5
Includes construction of toilet blocks, carrier counseling, promoting education, including special educational and employment enhancing vocation skills for students, etc.
3 Care for the Needy 1.5 1.5 1.5 1.3 1.3 Eradicating hunger, poverty and malnutrition. Identification of old age homes, orphanage, differently abled persons, etc. Take care of their requirements.
4 Health & Environment 6 5.5 4.5 4.5 4.5 Conducting general health camps in the nearby villages, government schools, Creating environmental awareness, display of materials, sapling of trees, etc.
5 Infrastructure 1.5 1.2 1.2 1 1 Take care of the local community by construction of bus shelters, providing facilities in the Government Primary Health Centers, Government Hospitals.
Total (Rs. Lakhs) 23.5 22.7 21.7 22.3 22.3 8.0 Transport systems
All the raw materials and finished products are transported by road. Dedicated parking
facility is provided for transport vehicles. The plant is located in an industrial area, and there
will not be any unauthorized shop or settlements along the road connecting the plant site.
There will be 10-12 truck trips per day to the factory. Traffic signs are placed in the battery
Hazelo Lab Pvt. Ltd. Environment Management Plan
1-32 Team Labs and Consultants
limit. The drivers of the vehicles will be provided with TREM cards and will be explained the
measure to be adopted during various emergencies.
9.0 Reduce, Recovery and Reuse (Terms of Reference No. 7(vii)
It is the endeavor of the project authorities to increase the yields of the products through
constant research and development activity. The development activity shall concentrate on
increasing the yields, using less quantity of raw material, using alternative solvents with low
hazards adopting green chemistry principles. The solvents shall be recycled for reuse in the
process by distillation. The mother liquors from the first crop shall be reused for process.
The cleaning cycles will be reduced by adopting appropriate production plan with minimum
changeovers of the product. Hydro jets or high pressure cleaning shall be adopted for
washing the reactors to minimize washing effluents. It is proposed to use third and fourth
washing water for first and second washing of the reactor and centrifuges. The steam
condensate shall be reused for boiler feed. Treated effluent is reused for cooling tower
makeup, while boiler blow down is reused for scrubbing. A cross functional team shall
constantly evaluate various options of reduce, reuse and recycle for water conservation,
reduction in wastewater generation, effluent segregation, reuse of wastes, alternate treatment
methods, leakage/spillage control, avoidance of overflow and contamination. As part of the
above exercise the proponent identified few compounds which can be recovered as
byproducts and sold. It is also proposed to explore recovery of various salts from MEE salts,
and from process effluents to reduce effluent loads, and quantity of solid waste.
10.0 Energy Conservation
It is proposed to use screw compressors (Air/Refrigeration) for energy efficiency (10 – 12%
saving), evaporative condensers in the chilling circuit to reduce overall power, Cooling tower
fan control to switch off at times not required (Low temp), energy efficient pumps to conserve
energy.
11.0 Green Belt Development (Terms of Reference No. 7(ix)
The Hazelo Lab Pvt. Ltd., is an existing chemical plant. Green belt is developed in an area of
1.8 acres, it is proposed to enhance the green belt area to 11.5 acres, covering the boundary of
Hazelo Lab Pvt. Ltd. Environment Management Plan
1-33 Team Labs and Consultants
the site as part of environment management plan. It has taken adequate measures for
prevention and control of pollution. It has a fully fledged Environment monitoring
management cell. Ggreenbelt plan presented in Fig. 1.5
Green Belt Photographs
Hazelo Lab Pvt. Ltd. Environment Management Plan
1-34 Team Labs and Consultants
SCALE 1Cm = 00 mtrs
PROD UCTION BLOCK40.0x12.5
PROPOSED BLOCK40.0x19.0
40.0x12.5
8.0X12.5MRO AD 5.0 M
DCPRO POSED
14.0X12.5MTANKS
RO AD 5.0 M
R OAD 7.0 M
SOLV ENT YARD45.3x60.0
LRM -II
40.0x20.0
U N LOA DING
PROPOSED B LOCK40.0x19.0
IN TER M EDIATE STORAGE
Q C& QA
PRO PO SED
70.0x19.0
PRO PO SED SERV ICE BLOCK70.0x12.5
R OA D 5.0 M
40.0x20.0
28.0x20.0
40.0x20.0
70.0x20.0
R OAD 5.0 M
40.0x20.0
40.0x20.0
70.0x20.0
RO AD 5.0 M 25.0x12.5BO ILER20.0x12.5
COAL SHED
PROPOSED B LOCKPROPOSED BLOCK
W AREH OU SE-I
LRM -I
50.0x20.0
40.0x20.0
W AR EHO U SE-II
CANTEEN &C HAN GE ROOM S
PROPOSED BLOCK
PRO PO SED PILO T PLANT
10.0x10.0
TEM PLE
FUTURE
FUTURE
FUTURE
ZLD System
FUTURE FUTURE
FUTUREFUTURE
FUTURE
STORM W ATERPOND
Fig 1.5 Green Belt Development of Hazelo Lab Pvt. Ltd.
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1-35 Team Labs and Consultants
12.0 Corporate Environmental Responsibility (Terms of Reference No. 9(i)
The broad guidelines of the Environmental Policy are presented below. The environmental
Management System shall have standard operating procedures for various aspects identified
which include infringement/deviation/violation of Environment related statutory
regulations:
Environmental Policy
Ensure that all our activities are carried out to avoid & control all foreseeable risks to
the health and safety of all people involved in the operations.
Protect the natural environment by prevention of pollution.
Optimize the use of resources through reduction, reuse, recycling, continuous research
and using efficient technologies.
Comply with all applicable Health, safety & Environment laws, regulations and other
requirements applicable our business.
Continually evaluate and improve the processes by setting the objective in the
direction to minimize hazards & environmental impacts arising out of operations.
Provide safe working environment to everyone in our premises with necessary
infrastructure.
Inculcate Health, safety & Environment awareness across the organization through
recognition, training and development.
Seek involvement of our employees and all stake holders in improving the operations
to ensure clean environment, safety & healthy work place for all.
We are dedicated to the continual improvement of the Health, safety & Environment
performance across our operations. We are of the firm belief that all our employees identify
and share this commitment, which would go a long way in earning the confidence of our
customers, stakeholders and the society.
13.0 Environment Management Cell (Terms of Reference No. 9(iii)& 9(iv))
Vice President – EHS will take the final responsibility for environmental management and
control. The Environmental Manager and staff will supervise the day-to-day activities of the
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1-36 Team Labs and Consultants
environmental management and control. The organ gram of the Environment management
cell is presented in Fig 1.8.
Sr. G. M. Operations
Dy. Manager‐EH&S
Executive‐Environment
Jr. Chemist‐Safety
Sr. Technician‐Environment
Jr. Supervisor Environment
Jr. Chemist ‐Environment
G.M. CEHS
VICE PRESIDENT
Fig 1.6 Organ gram of the Environment Management Cell
Records shall be maintained for the analysis of raw effluents and treated effluents, ambient
air quality data, stack emissions monitoring results, micro- meteorological data and noise
levels. These records are not only required for the perusal of the pollution control board
authorities but also to derive at the efficiencies of the pollution control equipment as the
objective of the project proponent is not only compliance with statutory regulations, but also
a serious commitment towards clean environment.
The industry shall be regularly maintaining the records as per the hazardous waste
regulations and EPA regulations and is applying for the annual consents for air and water,
and renewal of authorization for the storage of hazardous waste.
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1-37 Team Labs and Consultants
14.0 CREP Guideline and Compliance
CREP Guideline Compliance Segregation of waste streams Segregation of waste streams at source Detoxification and treatment of high COD waste streams
High COD waste streams are neutralized and detoxified as present practice
Management of solid waste Hazardous waste is sent to CHWTSDF. Minimum scale of production to afford cost of pollution control
Production capacities optimized.
Long term strategies for reduction in waste Reduction of waste generation by increasing the yields is a major R&D activity.
Control of air pollution Scrubbers provided to all vents and air emission of reactions apart from Bag filter to boilers.
Self – regulation by industry through regular monitoring and environmental auditing
Third party monitoring conducted quarterly
Optimizing the inventory of hazardous chemicals
Storage of chemicals optimized for one week.
15.0 Other Management Practices
The industry will maintain records as per the hazardous waste regulations and EPA
regulations and apply for the annual consents for air and water, and renewal of
authorization for the storage of hazardous waste as per Hazardous Waste (Handling &
Management) Rules, 1989 and subsequent amendments. The records of hazardous waste
manifest will be maintained.
The industry shall obtain the consent for operation (CFO) as required under section 25/26 of
the Water Act, 1974 and under section 21/22 of Air Act, 1981 before trial production and
commissioning from the Sate Pollution Control Board. The CFO will be renewed each year
by the industry. The industry will obtain the necessary permissions under Hazardous Waste
(Management and Handling) Rules 1989, and Manufacture, Storage and Import of
Hazardous Chemicals Rules, 1989, issued by the Ministry of Environment and Forests, New
Delhi. The industry will submit environmental statement every year before September 30,
and monthly water cess returns. The management ensures that it will comply with all the
directions and regulations issued by the Ministry of Environment and Forests, New Delhi,
State and Central Pollution Control Boards. The Consent for Establishment, Consent for
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1-38 Team Labs and Consultants
Operation will be displayed in a conspicuous location for the information of the inspecting
authorities of different departments.
16.0 Cost Estimate for Environment Management Plan (Terms of Reference No. 7(xi)
It is estimated that the total capital cost for implementing the Environment Management
plan is Rs. 1204.3 Lakhs, while the recurring costs for the same is Rs. 1593 Lakhs/year. The
cost estimate is presented in Table 1.16. The item wise tentative capital cost estimate for
environment management measures is presented in Table 1.17
1 Air pollution Control 392 55 2 Water pollution Control 682 1045 3 Noise pollution Control 9 2 4 Environment Monitoring and Management 20 9 5 Occupational Health 28.3 12 6 Green Belt 18 4 7 Others (S. Waste) 55 466
Total (Lakhs) 1204.3 1593 Note: Value in Rs. Lakhs
Table 1.17 Item Wise Tentative Capital Cost Estimate for Environment Management S.No Description Cost
(Rs. Lakhs) I Air pollution Bag Filter 70 Scrubbers 90 Condensors 72 Vaccum pumps 105 Spill control kits 0.48 Closed Hoods and AOD pumps 7.5 Dust Collectos 12 Coal handling system 15 Ash handling system 20 Total - I 392 II Safety Breather Valves 1 Rupture disks 1.4 Trolleys 0.2 Fire hydrant system 1 Gas detection system 3 Safety releif valves 3.75
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1-39 Team Labs and Consultants
Fire extinguishers 1 Fire buckets 0.08 Total - II 11.43
III Occupational safety Ocuupational safety and health centre with facilities 6 Self contained breathing apparatus 3.36 Personal protective equipment 5 Eye wash and body wash showers 2.5 Total - III 16.86
IV Water Effluent treatment system 600 Storm water drains 15 Storm water storage tank 30 Rain water harvesting structures 8 Fire hydrant storage tank 4 Effluent and sewage transfer lines 25 Total - IV 682 V Noise Acoustic enclosures 4 Guards, casing, attenuating screens 2.5 Vibration control pads 1.5 Others 1 Total - V 9
VI Solid waste Storage area for hazardous waste 40 Detoxification area 6 Ash handling system 9 Total - VI 55
VII Green Belt 18 Total - VIII 18
VIII Environmental monitoring Laboratory 15 Monitoring equipment 5 Total - VIII 20 Total (I+II+III+IV+V+VI+VII+VIII) 1204.3
HAZELO LAB PVT. LTD. SY.NO. 240, 242, 243, 247, 248 AND 249, DOTHIGUDEM VILLAGE, POCHAMPALLY MANDAL, YADRADI BHUVANAGIRI DISTRICT,
SUBMITTED TO TELANGANA STATE POLLUTION CONTROL BOARD,
REGIONAL OFFICE, NALGONDA
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Compliance of Terms of Reference Compliance of Standard TOR for “Synthetic Organic Chemicals Industry (dyes and dye
intermediates; bulk drugs and intermediates excluding drug formation; synthetic rubber; basic organic chemicals, other synthetic organic chemicals and chemical intermediates” Issued by
MoEF&CC for EIA/EMP report for Projects/Activates requiring Environmental Clearance Under EIA Notification, 2006
TOR Letter No. J-11011/19/2016-IA II (I) Date: 31.03.2016
S.No Compliance of Terms or Reference Response A. STANDARD TERMS OF REFERENCE
1 Executive Summary Included in EIA report. 2 Introduction i. Details of the EIA Consultant including
NABET accreditation EIA Consultants: Team Labs and Consultants List of QCI/NABET Consultants: S.No.147 (Rev. 51 - March 07, 2017)
ii. Information about the project proponent Presented in Chapter 1 of EIA report at Page No. 1-1
iii. Importance and benefits of the project Presented in Chapter 1 of EIA report at Page No. 1-1
3 Project Description i. Cost of project and time of completion. Cost of Project for Proposed Expansion
is 45 crores. ii. Products with capacities for the proposed
project. Presented in Chapter 1 of EIA report at Page No. 1-3 to 1-5
iii. If expansion project, details of existing products with capacities and whether adequate land is available for expansion, reference of earlier EC if any.
Presented in Chapter 1 of EIA report at Page No. 1-3 to 1-5. Additional land acquired for proposed expansion is 29.16 acres in addition to existing site area of 4.325 acres. Total land area after expansion is 33.485 acres.
iv. List of raw materials required and their source along with mode of transportation.
Presented in Chapter 6 of EIA report at Page No. 6-5
v. Other chemicals and materials required with quantities and storage capacities
Presented in Chapter 6 of EIA report at Page No. 6-5
vi. Details of Emission, effluents, hazardous waste generation and their management.
Presented in Environment Management Plan. Effluents: 1-4 to 1-12 Emissions: 1-13 to 1-20 Hazardous Waste: 1-21 to 1-22.
vii. Requirement of water, power, with source of supply, status of approval, water balance diagram, man-power requirement (regular and contract)
Total water required after expansion: 468.3 KLD Fresh water: 298.27 KLD Recycled water: 170 KLD Detailed water balance is presented in Chapter 2 of EIA Report at Page No. 2-100
viii. Process description along with major Presented in 2 of EIA Report at Page
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equipments and machineries, process flow sheet (quantative) from raw material to products to be provided
No. 2-3 to 2-99
ix. Hazard identification and details of proposed safety systems.
Presented in Chapter 6 of EIA report at Page No. 6-13 to 6-16.
x. Expansion/modernization proposals: a. Copy of all the Environmental Clearance(s)
including Amendments thereto obtained for the project from MOEF/SEIAA shall be attached as an Annexure. A certified copy of the latest Monitoring Report of the Regional Office of the Ministry of Environment and Forests as per circular dated 30th May, 2012 on the status of compliance of conditions stipulated in all the existing environmental clearances including Amendments shall be provided. In addition, status of compliance of Consent to Operate for the ongoing existing operation of the project from SPCB shall be attached with the EIA-EMP report.
Not Applicable
b. In case the existing project has not obtained environmental clearance, reasons for not taking EC under the provisions of the EIA Notification 1994 and/or EIA Notification 2006 shall be provided. Copies of Consent to Establish/No Objection Certificate and Consent to Operate (in case of units operating prior to EIA Notification 2006, CTE and CTO of FY 2005-2006) obtained from the SPCB shall be submitted. Further, compliance report to the conditions of consents from the SPCB shall be submitted.
M/s. Hazelo Lab Pvt. Ltd., (formerly known as Venlar Labs ( P ) Ltd., was established before 2006 EIA notification and involved in manufacturing of API intermediates. The unit had renewed consent and HW authorization (CFO) vide Letter No. TSPCB/RCP/NLG/16644/HO/2015-986 dated 14.08.2015 valid till 31.01.2018.
4 Site Details i. Location of the project site covering village,
Taluka/Tehsil, District and State, Justification for selecting the site, whether other sites were considered.
Hazelo Lab Pvt. Ltd . Sy.Nos. 240, 242, 243, 247, 248 and 249, Dothigudem Village, Pochampally Mandal, Yadadri Bhuvanagiri district, Telangana State. The proposal is for expansion of existing unit by acquiring additional land. Additional land acquired for proposed expansion is 29.16 acres in addition to existing site area of 4.325 acres. Total land area after expansion is 33.485 acres.
ii. A topo sheet of the study area of radius of 10km and site location on 1:50,000/1:25,000 scale on an A3/A2 sheet. (including all eco-
Presented in Chapter 1 of EIA report at Page No. 1-6.
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sensitive areas and environmentally sensitive places)
iii. Details w.r.t. option analysis for selection of site
Proposal is for expansion of existing plant site.
iv. Co-ordinates (lat-long) of all four corners of the site.
v. Google map-Earth downloaded of the project site.
Enclosed at Annexure - I
vi. Layout maps indicating existing unit as well as proposed unit indicating storage area, plant area, greenbelt area, utilities etc. If located within an Industrial area/Estate/Complex, layout of Industrial Area indicating location of unit within the Industrial area/Estate.
Plant layout is presented in Chapter 1 of EIA report at Page No. 1-9
vii. Photographs of the proposed and existing (if applicable) plant site. If existing, show Photographs of plantation/greenbelt, in particular.
Photographs of Plant site is presented in Chapter 3 of EIA report at Page No. 3-2
viii. Land use break-up of total land of the project site (identified and acquired), government/ private - agricultural, forest, wasteland, water bodies, settlements, etc shall be included. (not required for industrial area)
Plant layout is presented in Chapter 1 of EIA report at Page No. 1-9
ix. A list of major industries with name and type within study area (10km radius) shall be Incorporated. Land use details of the study area
Land use and Land Cover map of the study area is presented in Chapter 3 of EIA report at Page No. 3-7.
x. Geological features and Geo-hydrological status of the study area shall be included.
Presented in Chapter 3 of EIA report at Page No. 3-3 to 3-4
xi. Details of Drainage of the project upto 5km radius of study area. If the site is within 1 km radius of any major river, peak and lean season river discharge as well as flood occurrence Frequency based on peak rainfall data of the past 30 years. Details of Flood Level of the Project site and maximum Flood Level of the river shall also be provided. (mega green field projects)
Drainage pattern of the impact area is presented in Chapter 3 of EIA report at Page No. 3-14
xii. Status of acquisition of land. If acquisition is not complete, stage of the acquisition process
The proposal is for expansion of existing unit by acquiring additional
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and expected time of complete possession of the land.
land. Additional land acquired for proposed expansion is 29.16 acres in addition to existing site area of 4.325 acres. Total land area after expansion is 33.485 acres.
xiii. R&R details in respect of land in line with state Government policy.
Not Applicable. Expansion within existing site area.
5 Forest and wildlife related issues (if applicable): i. Permission and approval for the use of forest
land (forestry clearance), if any, and recommendations of the State Forest Department. (if applicable)
Not Applicable
ii. Land use map based on High resolution satellite imagery (GPS) of the proposed site delineating the forestland (in case of projects involving forest land more than 40 ha)
The proposal is for expansion of existing unit by acquiring additional land, however land use map is presented in Chapter 3 of EIA report at Page No. 3-7
iii. Status of Application submitted for obtaining the stage I forestry clearance along with latest status shall be submitted.
Not Applicable
iv. The projects to be located within 10 km of the National Parks, Sanctuaries, Biosphere Reserves, Migratory Corridors of Wild Animals, the project proponent shall submit the map duly authenticated by Chief Wildlife Warden showing these features vis-à-vis the project location and the recommendations or comments of the Chief Wildlife Warden-thereon.
There are no National Parks, Sanctuaries, Biosphere Reserves, Migratory Corridors of Wild Animals within the impact area of 10 km.
v. Wildlife Conservation Plan duly authenticated by the Chief Wildlife Warden of the State Government for conservation of Schedule I fauna, if any exists in the study area.
Not Applicable
vi. Copy of application submitted for clearance under the Wildlife (Protection) Act, 1972, to the Standing Committee of the National Board for Wildlife.
Not Applicable
6 Environmental Status i. Determination of atmospheric inversion level at
the project site and site-specific micrometeorological data using temperature, relative humidity, hourly wind speed and direction and rainfall.
Site-specific micrometeorological data presented in Chapter 3 of EIA report at Page No. 3-22 to 3-24
ii. AAQ data (except monsoon) at 8 locations for PM10, PM2.5, SO2, NOX, CO and other parameters relevant to the project shall be collected. The monitoring stations shall be based CPCB guidelines and take into account the pre-dominant wind direction, population zone and sensitive receptors including reserved
AAQ data presented in Chapter 3 of EIA report at Page No. 3-29 to 3-30
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forests. iii. Raw data of all AAQ measurement for 12
weeks of all stations as per frequency given in the NAQQM Notification of Nov. 2009 along with - min., max., average and 98% values for each of the AAQ parameters from data of all AAQ stations should be provided as an annexure to the EIA Report.
AAQ data is presented in Chapter 3 of EIA report at Page No. 3-29 to 3-30.
iv. Surface water quality of nearby River (100m upstream and downstream of discharge point) and other surface drains at eight locations as per CPCB/MoEF&CC guidelines.
Surface water quality is presented in Chapter 3 of EIA report at Page No. 3-12.
v. Whether the site falls near to polluted stretch of river identified by the CPCB/MoEF&CC, if yes give details.
No.
vi. Ground water monitoring at minimum at 8
locations shall be included. Ground Monitoring locations presented in Chapter 3 of EIA report at Page No. 3-13 to 3-18.
vii. Noise levels monitoring at 8 locations within the study area.
Noise levels monitoring is presented in Chapter 3 of EIA report at Page No. 3-30 to 3-32
viii. Soil Characteristic as per CPCB guidelines. Soil Characteristics is presented in Chapter 3 of EIA report at Page No. 3-9
ix. Traffic study of the area, type of vehicles, frequency of vehicles for transportation of materials, additional traffic due to proposed project, parking arrangement etc.
The additional traffic generated due to the proposed expansion shall be 10 - 12 truck trips per day.
x. Detailed description of flora and fauna (terrestrial and aquatic) existing in the study area shall be given with special reference to rare, endemic and endangered species. If Schedule-I fauna are found within the study area, a Wildlife Conservation Plan shall be prepared and furnished.
Flora and Fauna of the Impact area is presented in Chapter 3 of EIA report at Page No. 3-39 to 3-49.
xi. Socio-economic status of the study area. Socio-Economic status of the impact area is presented in Chapter 3 of EIA report at Page No. 3-33 to 3-38
7 Impact and Environment Management Plan i. Assessment of ground level concentration of
pollutants from the stack emission based on site-specific meteorological features. In case the project is located on a hilly terrain, the AQIP Modelling shall be done using inputs of the specific terrain characteristics for determining the potential impacts of the project on the AAQ. Cumulative impact of all sources of emissions (including transportation) on the AAQ of the area shall be assessed. Details of the model used and the input data used for modelling shall also be provided. The air quality contours shall be plotted on a location
Predictions of ground level concentrations using ISC-AERMOD using ISCST3 model is of the pollutants presented in Chapter 4 of EIA report at Page No. 4-16 to 4-24. There will be 10 - 12 truck trips per day after expansion. Emissions considered from transport of vehicles as line source.
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map showing the location of project site, habitation nearby, sensitive receptors, if any.
ii. Water Quality modelling - in case of discharge in water body
Not applicable Total effluent generated sent to “Zero Liquid Discharge“System
iii. Impact of the transport of the raw materials and end products on the surrounding environment shall be assessed and provided. In this regard, options for transport of raw materials and finished products and wastes (large quantities) by rail or rail-cum road transport or conveyor cum- rail transport shall be examined.
There will be 10 - 12 truck trips per day. Truck transport Incidents and concerns are presented in Chapter 6 of EIA report at Page No. 6-43.
iv. A note on treatment of wastewater from different plant operations, extent recycled and reused for different purposes shall be included. Complete scheme of effluent treatment. Characteristics of untreated and treated effluent to meet the prescribed standards of discharge under E (P) Rules.
Quantity, quality of effluent generated from different operation is presented in Environment Management Plan of EIA report at Page No. 1-4.
Effluent Treatment System (ZLD) is presented in Environment Management Plan of EIA report at Page No. 1-6 to 1-12.
v. Details of stack emission and action plan for control of emissions to meet standards.
Presented in Environment Management Plan of EIA report at Page No. 1-13.
vi. Measures for fugitive emission control Presented in Environment Management Plan of EIA report at Page No. 1-18.
vii. Details of hazardous waste generation and their storage, utilization and management. Copies of MOU regarding utilization of solid and hazardous waste in cement plant shall also be included. EMP shall include the concept of waste-minimization, recycle/reuse/recover Techniques, Energy conservation, and natural resource conservation.
Presented in Environment Management Plan of EIA report at Page No. 1-21 to 1-22. Reduce, reuse and recycled concept is presented in waste-minimization, Energy conservation is presented in Environment Management Plan of EIA report at Page No. 1-32.
viii. Proper utilization of fly ash shall be ensured as per Fly Ash Notification, 2009. A detailed plan of action shall be provided.
Ash generated from boiler send to brick manufactureres.
ix. Action plan for the green belt development plan in 33 % area i.e. land with not less than 1,500 trees per ha. Giving details of species, width of plantation, planning schedule etc. shall be included. The green belt shall be around the project boundary and a scheme for greening of the roads used for the project shall also be incorporated.
11.5 acres allocated for green area. Layout showing green belt development is presented in Environment Management Plan at Page No. 1-33 to 1-34.
x. Action plan for rainwater harvesting measures at plant site shall be submitted to harvest rainwater from the roof tops and storm water drains to recharge the ground water and also
Presented in Environment Management Plan of EIA report at Page No. 1-23 to 1-25.
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to use for the various activities at the project site to conserve fresh water and reduce the water requirement from other sources.
xi. Total capital cost and recurring cost/annum for environmental pollution control measures shall be included.
Total Capital Cost: Rs. 45 crores EMP Cost estimate: Rs. 12.04 crores Recurring Cost on EMP: Rs. 15.93 crores /annum. Details are presented in Environment Management Plan at Page no. 1-38.
xii. Action plan for post-project environmental monitoring shall be submitted.
Presented in Chapter 5 of EIA report at Page No. 5-8.
xiii. Onsite and Offsite Disaster (natural and Man-made) Preparedness and Emergency Management Plan including Risk Assessment and damage control. Disaster management plan should be linked with District Disaster Management Plan.
Disaster Management Plan is presented in Chapter 6 of EIA report at Page No.6-47.
Onsite and Offsite Disaster is presented in Chapter 6 of EIA report at Page No.6-48.
8 Occupational Health i. Plan and fund allocation to ensure the
occupational health & safety of all contract and casual workers
Total: 80 Lakhs/annum PPE: 60 Lakhs/annum Health Check-up: 20 Lakhs/annum
ii. Details of exposure specific health status evaluation of worker. If the workers' health is being evaluated by pre designed format, chest x rays, Audiometry, Spirometry, Vision testing (Far & Near vision, colour vision and any other ocular defect) ECG, during pre placement and Periodical examinations give the details of the same. Details regarding last month analyzed data of above mentioned parameters as per age, sex, duration of exposure and department wise.
Medical health check-up is Environment Management Plan of EIA report at Page No. 1-27 to 128.
iii. Details of existing Occupational & Safety Hazards. What are the exposure levels of hazards and whether they are within Permissible Exposure level (PEL). If these are not within PEL, what measures the company has adopted to keep them within PEL so that health of the workers can be preserved,
Presented in Environment Management Plan of EIA report at Page No. 1-26 to 1-27.
Suitable PPE is prescribed to the employees working in area where the conc. Exceeds PEL values. Simultaneously the project and R&D team are consulted to suggest mitigative measures and or engineering control measures.
The focus shall always be in ensuring concentration within PEL by adopting engineering controls as when requires.
iv. Annual report of heath status of workers with special reference to Occupational Health and Safety.
Annual report of Health Status of workers will maintained
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9 Corporate Environment Policy i. Does the company have a well laid down
Environment Policy approved by its Board of Directors? If so, it may be detailed in the EIA report.
Corporate Environment Policy is presented in Environment Management Plan of EIA report at Page No. 1-35.
ii. Does the Environment Policy prescribe for standard operating process / procedures to bring into focus any infringement / deviation / violation of the environmental or forest norms / conditions? If so, it may be detailed in the EIA.
Environment engineer is responsible to bring to focus to higher management in case of deviation/ violation of the environmental or forest norms / conditions.
iii. What is the hierarchical system or Administrative order of the company to deal with the environmental issues and for ensuring compliance with the environmental clearance Conditions? Details of this system may be given.
Environment Management Cell is presented in Environment Management Plan of EIA report at Page No. 1-35.
iv. Does the company have system of reporting of non compliances / violations of environmental norms to the Board of Directors of the company and / or shareholders or stakeholders at large? This reporting mechanism shall be detailed in the EIA report
Yes. Environment Management Cell is presented in Environment Management Plan of EIA report at Page No. 1-35.
10 Details regarding infrastructure facilities such as sanitation, fuel, restroom etc. to be provided to the labour force during construction as well as to the casual workers including truck drivers during operation phase.
Presented in Environment Management Plan of EIA report at Page No. 1-2.
11 Enterprise Social Commitment (ESC) i. Adequate funds (at least 2.5 % of the project
cost) shall be earmarked towards the Enterprise Social Commitment based on Public Hearing issues and item-wise details along with time bound action plan shall be included. Socio-economic development activities need to be elaborated upon.
Corporate Social Responsibilities – Budget is presented in Environment Management Plan of EIA report at Page No. 1-30 to 1-31.
12 Any litigation pending against the project and/or any direction/order passed by any Court of Law against the project, if so, details thereof shall also be included. Has the unit received any notice under the Section 5 of Environment (Protection) Act, 1986 or relevant Sections of Air and Water Acts? If so, details thereof and compliance/ATR to the notice(s) and present status of the case.
No Individual Court case against the Project.
13 A tabular chart with index for point wise compliance of above TOR.
Enclosed at Compliance of Terms of Reference along with EIA & EMP.
Hazelo Lab Pvt. Ltd. TOR Compliances
Page 9
B. SPECIFIC TERMS OF REFERENCE FOR EIA STUDIES FOR SYNTHETIC ORGANIC CHEMICALS INDUSTRY (DYES & DYE INTERMEDIATES; BULK DRUGS AND INTERMEDIATES EXCLUDING DRUG FORMULATIONS; SYNTHETIC RUBBERS; BASIC ORGANIC CHEMICALS, OTHER SYNTHETIC ORGANIC CHEMICALS AND CHEMICAL INTERMEDIATES)
1 Details on solvents to be used, measures for solvent recovery and for emissions control.
Details of solvents used and balance is presented in Chapter 2 of EIA report at Page No. 2-121 to 2-129.
2 Details of process emissions from the proposed unit and its arrangement to control.
Details of process emissions is presented in Chapter 2 of EIA report at Page No. 2-118 to 2-120
3 Ambient air quality data should include VOC, other process-specific pollutants* like NH3*, chlorine*, HCl*, HBr*, H2S*, HF*,etc., (*-as applicable)
AAQ data is presented in Chapter 3 of EIA report at Page No. 3-29
4 Work zone monitoring arrangements for hazardous chemicals.
Presented in Chapter 5 of EIA report at Page No. 5-10.
5 Detailed effluent treatment scheme including segregation of effluent streams for units adopting 'Zero' liquid discharge.
Details of Effluent Treatment System (ZLD) are presented in Environment Management Plan of EIA report at Page No. 1-6 to 1-12.
6 Action plan for odour control to be submitted. Presented in Environment Management Plan of EIA report at Page No. 1-18.
7 A copy of the Memorandum of Understanding signed with cement manufacturers indicating clearly that they co-process organic solid/hazardous waste generated.
Enclosed at Annexure
8 Authorization/Membership for the disposal of liquid effluent in CETP and solid/hazardous waste in TSDF, if any.
Enclosed at Annexure
9 Action plan for utilization of MEE/dryers salts. Salts generated from MEE/ATFD sent to TSDF.
10 Material Safety Data Sheet for all the Chemicals are being used/will be used.
Enclosed at Annexure
11 Authorization/Membership for the disposal of solid/hazardous waste in TSDF.
Enclosed at Annexure
12 Details of incinerator if to be installed. Not Applicable. Organic waste sent to cements plant for co-incineration.
13 Risk assessment for storage and handling of hazardous chemicals/solvents. Action plan for handling & safety system to be incorporated.
Presented in Chapter 6 of EIA report at Page No.6-32 to 6-39.
14 Arrangements for ensuring health and safety of workers engaged in handling of toxic materials.
Presented in Chapter 6 of EIA report at Page No.6-412 to 6-43.
B. ADDITIONAL TOR 1 Public hearing to be conducted and issues raised and
commitments made by the project proponent on the same should be included in EIA/EMP report in the form of tabular chart with financial budget for complying with the commitments made.
2 A copy of compliance report to the Environmental M/s. Velar Labs Pvt. Ltd., obtained
Hazelo Lab Pvt. Ltd. TOR Compliances
Page 10
conditions prescribed in the existing EC. Action taken report/ detailed action plan on the partly/non-compliance conditions reported by the MoEF&CC Regional Office.
Environment Clearance for Modernization of Synthetic Organic Chemicals vide order No. F. No. 11011/87/2010 - IA II (I) dated 23.11.2010 for change of product mix, which was not implemented.
3 Existing EC required to be changed in the name from M/s. Venlar Labs Pvt. Ltd to M/s. Hazelo Lab Pvt. Ltd.
Not Applicable. Velar Labs Pvt. Ltd., obtained Environment Clearance for Modernization of Synthetic Organic Chemicals vide order No. F. No. 11011/87/2010 - IA II (I) dated 23.11.2010 for change of product mix, which was not implemented
HAZELO LAB PVT. LTD. SY.NO. 240, 242, 243, 247, 248 AND 249, DOTHIGUDEM VILLAGE, POCHAMPALLY MANDAL, YADRADI BHUVANAGIRI DISTRICT,
STUDIES AND DOCUMENTATION BY TEAM Labs and Consultants B‐115‐117 & 509, Annapurna Block, Aditya Enclave, Ameerpet, Hyderabad‐500 038. Phone: 040‐23748 555/23748616, Telefax: 040‐23748666
SUBMITTED TO TELANGANA STATE POLLUTION CONTROL BOARD,
REGIONAL OFFICE, NALGONDA
M/S. HAZELO LAB PRIVAE LIMITED (Formerly M/s. Velar Labs Private Limited), Dhotigudem, Pochampally(M), Yadadri dist.Consent for Operation condition wise status report vide consent no. TSPCB/RCP/NGL/16644/HO/2015‐986 DT.14/08/2015.
SHEDULE‐AS.no CFO Conditions Condition wise status report1 The applicant shall make applications through online for renewal of
consent (under water and air Acts)and authorization under HWM rules at least 120 days before the date of expiry of this order ,along with prescribed fee under water and air acts for obtaining consent&HW authorization of the board along with detailed compliance to the conditions stipulated in the CFO and HWA order.
Complying with this condition
2 Concealing the factual data or submission of false information/fabricated data and failure to comply with any of the conditions mentioned in this order may result in withdrawal of this order and attract action under the provisions of relevant pollution control acts
Noted
3 Any person aggrieved by an order made by the state board under section 25,section26,section27Of water act,1974 or section 21 of Air Act,1981 may within thirty days from the date on which the order is communicated to him,prefer an appeal as per Andhra Pradesh water rules,1976 and Air rules 1982,to such authority (hereinafter referred to as the appellate Authority)constituted under section 28 of the Water (prevention and conteol of pollution )Act 1974 and section 31 of the Air(Preventation and Control of Pollution)Act,1981
The industry is following all rules and regulations in accordance with Air & Water act rules.
4 The industry may explore the posibility of tapping the solar energy for their enery requirements.
We will explore the possibility of solar energy requirements in the plant premises.
5 All he conditions stipulated in the shedule ‐A earlier combined CFO &HWA order No.APPCB/RCP/NLG/98/CFO/HO/2012‐4076 Date:12.11.2012 remains same.the industry should ensure consistence complience of each condition of Shedule‐A.
The industry is complying Schedule‐A conditions of CFO & HWA Order dated 12/11/2012.
6 The board reserves its right to modify above conditions or stipulate any further conditions and to take action including revoke of this order in the intrest of protection of public health environment.
Noted
7 SCHEDULE‐B8 The industry should take steps to reduce water consumption to the
extent possible and consumption should not exceed the quantities prescribed below: 1.process& washings:‐8.06KLD 2.Floor washings:‐1.0KLD 3.Boiler Feed :‐1.5KLD 4.Cooling tower make up:‐2.0 KLD 5.Domestic:‐1.2 KLD
The industry is consuming water within the limit which is pescribed in the Consent.
9 The industry should file the water cess returns in form ‐I as required under section(5) of water(Prevention and control of pollution)Cess,1977 on or before the 5th of every calander month,showing the quantity of water consumed in the previous month along with water meter readings.The industry should remit water cess as per the assessment orders as and when isssued by board
Complying with this condition
10 The emissions should not contain constituents in excess of the presscribed limits mentioned below:‐ A)chimney 1&2 particulate matter‐Emission standards‐115mg/NM3 B)chimney 3 parameter HCL Acid Vapour&mist Emission Standrds‐35mg/NM3
The industry is carrying thrid party monitoring and same has been submitting periodically to Regional Office. The emissions are not exceed the parameters as pescribed by the Board.
11 The industry should comply with emission limits for DG sets of capacity up to 800kw as per the notifiation G.S.R,520(E),dated 01.07.2003 under theenvironment(protection)Amendment rules,2003and G.S.R 448(E) dated 12.07.2004 under the environment protection(protection)second amendment rules,2004.In case of DG sets of capacity more than 800kw should comply with emission limits as per the notification G.S.R 489(E),dated 09.07.2002 at serial no.96, under the environment (protection)Act,1986
Complying with this condition
12 The industry should comply with ambient air qaulity standards of PM10(particulate Matter sizeless than 10µm)‐100µg/M3;PM2.5(particulate matter size less than 2.5µm)‐60µg/mg3;SO2‐80µg/M3;Nox‐80µg/m3,out side the factory premises at the periphery of the industry.Standards for other parameters as mentioned in the national Ambient Air quality standards CPCB Notification No‐B‐29016/20/90/PCI‐I,dated 18.11.20009 Noise levels: day time(6AM to 10PM)75dB(A) night time:10PM to 6AM)‐70dB(A)
The ambient air quality and noise level parameter and Noise levels are within the limits as pescribed in C.F.O. The industry is carrying third party monitoring periodically and same has been submitting in Regional Office.
13 The idustry shall manifacture only the consented products. Complying with this condition
14 The industry shall not increase the capacity beyond the permitted capacity with out obtaining CFE&CFO of the board
Complying with this condition
15 The industry shall segregate the HTDS<DSeffluents The generated entire effluents are treating in Stripper/MEE followed by Nutch filter as High TDS. The quantity of Low TDS effluent generation is very less hence there is no separation.
16 The industry shall regulary operate the existing stripper,multiple effect evaporater(MEE),etc.The Industry shall install the ATFD,Biological ETP,RO plant etc., in a time bound manner to achive ZLD.
Biological ETP,ATFD and RO plant are under installation and complete in time bound manner to acchieve ZLD.
17 The industry shall send HTDS EFLUENT TO THE MEE system of M/s.JETL,Jeedimetla for a period maximum 15 days in a calander year i.e.,during maintanence /break down of stripper,MEE &ATFD system and shall maintain records.
Agreed and will be followed
18 The industry can send LTDS effulents to CETP for a priod of Mximum15 days in a calender year i.e,during maintanence /break down of RO system and shall maintain records.
Agreed and will be followed
19 The industry shall not operate the 4TPH coal fired boiler with out obtaining CFE&CFO the Board.
The industry is dismantled 4 TPH coal fired boiler.
20 The industry shall install &operate water for recording category‐wise water consumption
The industry is installed water meters and recording water consumption category‐wise.
21 The industry shall install &operate digital flow meters for inllet of LTDS&HTDS effluents;MEE feed,MEE condensate;steam flow to stripper MEE,RO feed ;RO permeate;RO reject etc
The industry is provided digital flow meters for inlet and out let to meassure the generated quantity of effluents.
22 The industry shall install &operate VOC analyzes for monitoring of VOCs.
The industry is provided VOC analyzer portable mobile hand set to mesure the VOC analysis.
23 The industry shall install&operate multi stage scrubbers in the plant for control of process emissions.The industry should operate and maintain the scrubbers to scrub pocess emissions.at all emissions sources.THE Details of chemical consumption used in the scrubber should be recorded&kept accessible for the inspection officials of the board.
The industry has provided multi stage scrubbers in the plant for control of process emissions.
24 The industry shall provide online ph meters for the Multi ‐stage scrubbers.
Provided online pH meters for the multi stage scrubbers.
25 The industry shall provide separate energy meter for the pollution control systems and maintain the records of the same.
The industry has provided energy meter for the pollution control systems and maintaining the records of the same.
26 The industry shall provide vent condensers for all the bulk storage tanks .storing highly voltaile solvents to prevent escaping of fugitive emissions&should maintain the same effectively.
Complying with this condition
27 The industry shall immediately install&operate IP camera with PAN,TILT Zoom,5x or above focal length with night vision capability.
Complied with this condition
28 the industry shall comply with the directions issued by the task force from time to time
The industry wil follow the all the directions issued by the task force from time to time.
29 The industry should maintain log books on the following. A.Hydraulic loads of effluent generation B.Characteristics of effluents forced evaporated C.Quantity of effluents forced evaporated D.Condensate genaration and reuse E.Furnish consolidated daily records on the above periadically once in three months to the RO,Nalgonda.
The industry is maintaining all records and same will be available to the board officials when they have to visit the plant.
30 The industry should ensure detoxification in environmentally sound manner of various drums,linerscontainersand other materials that are in contact with bromine compoundsand details should be furnised to the board.
Will be Comply with this condition
31 There should not be any spillages/chemicals/effluents on ground.The drums containing chemicals &wates should be stored on elevated platform with a provision to collect leachate/spillages in the collection pit.In no case drums should be stored on the naked open ground the industry should insure the treatment facilities should be impervious to prevent ground water pollution
The industry is storing drums containing chemicals & wastes on elevated platform with a provision to collect leachate/spillages in the collection pit to avoide ground water pollution.
32 The industry should insure the treatment facilities should impervious to prevent ground water pollution
The industry is maintaining effective treatment facility to treat the generated effluents in proper way to prevent ground water pollution.
33 The industry should maintain the consolidated daily records on the following. A.Effluent generated B.quantity of treated effluents evaoprated in the forced evaporation system C.Quantity of condensate generation D.Characterstics solidwaste genaration should be submittedto the regional office,Nalgondafor every month.
The industry is maintaining all records and same will be available to the board officials when they have to visit the plant.
34 The industry should maintain the following recordsand the same should be made available to the inspection officer. A.Daily production details,RG‐1records and central excise returns. B.Quantitity of effluents gnerated and forced evaoprated. C.Log book for pollution control systems. D.Daily solid waste generatedand disposed to TSDF
The industry is maintaining all records and same will be available to the board officials when they have to visit the plant.
35 Under no circumstances the effluents should be used for land application.
Agreed
36 The industry should maintain records for the consistent performance of solvent recovery system for each stream‐wise and should furnish plan of action to achieve the efficiency of solvent recovery more than 95%for every stream.
Complying with this condition
37 The industry should take all safety measures and provide fire fighting equipment in the plant.
as per safety point of view we arranged all types of fire extingushers,water hydrant system,PRV,SRV rupture disk etc..
38 The industry should not discharge any waste water outside the factory premises and maintain zero discharge of effluents.
The industry is treating the generated effluents in stripper followed by MEE and not discharging outside the factory premises.
39 Thick green belt should be devolped &maintain by the industry with tall growing tress in the vacant spaces of the unit.
The industry is maintaining greenary around 45% of palnt occupy
40 The industry sould submit mock drill report carried out at least once in six months as required under the manufacture storage and import of Hazardous chemicals rules,1989
The industry is conducting mock drill to protect the environmenal issues once in six months and same will be submit to Regional Office within week period.
41 The applicant shall submit environment statement in form V before 30th september of every year as per RuleNo.14 of E(P) Rules,1986&amendments.
Complying with this condition
42 All the rules ®ulations notified by ministry of law and justice,Government of india regarding public liability insurance Act1991,should be followed.
Noted and agreed
43 The conditions are without prejudice to the rights and contentions of this Board any Hon'blecourt of law
Noted and agreed
SECTION‐C44 The industry should give top priority for waste minimization and
production practiesThe industry has given top priority for minimization of waste and production practies.
45 The industry should not store hazardous waste for more than 90 days a per the hazardous wastes (Management Handling and transboundary Movement)rules,2008and amendments thereof.
Complying with this condition
46 The industry should store used/waste oils and used lead batteries in secured way in their permises till its disposal
Complying with this condition
47 The industry should not dispose waste oils to the traders and the same should be disposed to the authorized reprocessors/Recyclers.
Complying with this condition
48 The industry should disposed used lead acid batteries to manifactures/dealers on buyback basis.
Complying with this condition
49 The industry should not dispose spent solvents/,mixed spent solventsto the traders.
Complying with this condition
50 The industry shoud take necessary practical stepsfor prevention of oil spillages and carry over of oil from the premises.
The industry is taken adequate measures to prevent oil spillages and carry over of oil from the premises.
51 The industry should maintain 6 copy manifest system for transportation of waste generated and a copy should be submitted to board office and concerned regional office
Complying with this condition
52 The industry should maintain good house keeping &maintain proper records for hazardous wastes stated in authorization.
The industry is maintaining good house keeping and maintaining proper records for hazardous wastes.
53 The industry should maintain proper records for hazardous wastes stated in authorization in FORM‐ i.e.,quantity of incinerable waste,land disposal waste,recyclable waste etc.,and file annual returns in form‐4 as per rule 22(2) of the Hzardous wastes (Management Handling&Transboundary movement)rules,2008 and amendments thereof.
complying with this condition
54 The industry should submit the condition wise compliance report of the conditions stipulated in shdule B&C of this order on half yearly basis to board office,hyderabad and concerned regional office.
Complying with this condition
55 The industry should dispose of e‐waste to the authorized recyclers only.
Complying with this condition
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Material Safety Data SheetAcetic acid MSDS
Section 1: Chemical Product and Company Identification
Potential Acute Health Effects:Very hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Hazardous in case of skincontact (corrosive, permeator), of eye contact (corrosive). Liquid or spray mist may produce tissue damage particularly onmucous membranes of eyes, mouth and respiratory tract. Skin contact may produce burns. Inhalation of the spray mist mayproduce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath. Inflammation of theeye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or,occasionally, blistering.
Potential Chronic Health Effects:Hazardous in case of skin contact (irritant), of ingestion, of inhalation. CARCINOGENIC EFFECTS: Not available.MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast. TERATOGENICEFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic to kidneys, mucousmembranes, skin, teeth. Repeated or prolonged exposure to the substance can produce target organs damage. Repeated
or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolongedexposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.
Section 4: First Aid Measures
Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. Get medical attention immediately.
Skin Contact:In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothingand shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly cleanshoes before reuse. Get medical attention immediately.
Serious Skin Contact:Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medicalattention.
Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention immediately.
Serious Inhalation:Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Ifbreathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. WARNING: It maybe hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled material is toxic, infectious orcorrosive. Seek immediate medical attention.
Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: Flammable.
Auto-Ignition Temperature: 463°C (865.4°F)
Flash Points: CLOSED CUP: 39°C (102.2°F). OPEN CUP: 43°C (109.4°F).
Flammable Limits: LOWER: 4% UPPER: 19.9%
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances:Flammable in presence of open flames and sparks, of heat. Slightly flammable to flammable in presence of oxidizingmaterials, of metals.
Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available. Slightly explosive in presence of oxidizing materials.
Fire Fighting Media and Instructions:Flammable liquid, soluble or dispersed in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use alcohol foam,water spray or fog. Cool containing vessels with water jet in order to prevent pressure build-up, autoignition or explosion.
Special Remarks on Fire Hazards:Reacts with metals to produces flammable hydrogen gas. It will ignite on contact with potassium-tert-butoxide. A mixture ofammonium nitrate and acetic acid ignites when warmed, especially if warmed.
Special Remarks on Explosion Hazards:
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Acetic acid vapors may form explosive mixtures with air. Reactions between acetic acid and the following materialsare potentially explosive: 5-azidotetrazole, bromine pentafluoride, chromium trioxide, hydrogen peroxide, potassiumpermanganate, sodium peroxide, and phorphorus trichloride. Dilute acetic acid and dilute hydrogen can undergo anexothermic reaction if heated, forming peracetic acid which is explosive at 110 degrees C. Reaction between chlorinetrifluoride and acetic acid is very violent, sometimes explosive.
Section 6: Accidental Release Measures
Small Spill:Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container. Ifnecessary: Neutralize the residue with a dilute solution of sodium carbonate.
Large Spill:Flammable liquid. Corrosive liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. If theproduct is in its solid form: Use a shovel to put the material into a convenient waste disposal container. If the product is inits liquid form: Absorb with DRY earth, sand or other non-combustible material. Do not get water inside container. Absorbwith an inert material and put the spilled material in an appropriate waste disposal. Do not touch spilled material. Use waterspray curtain to divert vapor drift. Prevent entry into sewers, basements or confined areas; dike if needed. Call for assistanceon disposal. Neutralize the residue with a dilute solution of sodium carbonate. Be careful that the product is not present at aconcentration level above TLV. Check TLV on the MSDS and with local authorities.
Section 7: Handling and Storage
Precautions:\Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do notbreathe gas/fumes/ vapor/spray. Never add water to this product. In case of insufficient ventilation, wear suitable respiratoryequipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin andeyes. Keep away from incompatibles such as oxidizing agents, reducing agents, metals, acids, alkalis.
Storage:Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed andsealed until ready for use. Avoid all possible sources of ignition (spark or flame).
Section 8: Exposure Controls/Personal Protection
Engineering Controls:Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respectivethreshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.
Personal Protection:Splash goggles. Synthetic apron. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves(impervious).
Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.
Water/Oil Dist. Coeff.: The product is more soluble in water; log(oil/water) = -0.2
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water, diethyl ether, acetone.
Solubility:Easily soluble in cold water, hot water. Soluble in diethyl ether, acetone. Miscible with Glycerol, alcohol, Benzene, CarbonTetrachloride. Practically insoluble in Carbon Disulfide.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Heat, ignition sources, incompatible materials
Incompatibility with various substances: Reactive with oxidizing agents, reducing agents, metals, acids, alkalis.
Corrosivity:Highly corrosive in presence of stainless steel(304). Slightly corrosive in presence of aluminum, of copper. Non-corrosive inpresence of stainless steel(316).
Special Remarks on Reactivity:Reacts violently with strong oxidizing agents, acetaldehyde, and acetic anhydride. Material can react with metals, strongbases, amines, carbonates, hydroxides, phosphates, many oxides,cyanides, sulfides, chromic acid, nitric acid, hydrogenperoxide, carbonates. ammonium nitrate, ammonium thiosulfate, chlorine trifluoride, chlorosulfonic acid, perchloric acid,permanganates, xylene, oleum, potassium hydroxide, sodium hydroxide, phosphorus isocyanate, ethylenediamine, ethyleneimine.
Special Remarks on Corrosivity: Moderate corrosive effect on bronze. No corrosion data on brass
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion.
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Toxicity to Animals:WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE. Acute oraltoxicity (LD50): 3310 mg/kg [Rat]. Acute dermal toxicity (LD50): 1060 mg/kg [Rabbit]. Acute toxicity of the vapor (LC50): 56201 hours [Mouse].
Chronic Effects on Humans:MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast. May cause damage tothe following organs: kidneys, mucous membranes, skin, teeth.
Other Toxic Effects on Humans:Extremely hazardous in case of inhalation (lung corrosive). Very hazardous in case of skin contact (irritant), of ingestion, .Hazardous in case of skin contact (corrosive, permeator), of eye contact (corrosive).
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: May affect genetic material and may cause reproductive effects based onanimal data. No human data found.
Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: Extremely irritating and corrosive. Causes skin irritation (reddening and itching,inflammation). May cause blistering , tissue damage and burns. Eyes: Extremely irritating and corrosive. Causes eye irritation,lacrimation, redness, and pain. May cause burns, blurred vision, conjunctivitis, conjunctival and corneal destruction andpermanent injury. Inhalation: Causes severe respiratory tract irritation. Affects the sense organs (nose, ear, eye, taste),and blood. May cause chemical pneumonitis, bronchitis, and pulmonary edema. Severe exposure may result in lung tissuedamage and corrosion (ulceration) of the mucous membranes. Inhalation may also cause rhinitis, sneezing, coughing,oppressive feeling in the chest or chest pain, dyspnea, wheezing, tachypnea, cyanosis, salivation, nausea, giddiness,muscular weakness. Ingestion: Moderately toxic. Corrosive. Causes gastrointestinal tract irritation (burning and pain of themouth, throat, and abdomen, coughing, ulceration, bleeding, nausea, abdomial spasms, vomiting, hematemesis, diarrhea.May Also affect the liver (impaired liver function), behavior (convulsions, giddines, muscular weakness), and the urinarysystem - kidneys (Hematuria, Albuminuria, Nephrosis, acute renal failure, acute tubular necrosis). May also cause dyspneaor asphyxia. May also lead to shock, coma and death. Chronic Potential Health Effects: Chronic exposure via ingestion maycause blackening or erosion of the teeth and jaw necrosis, pharyngitis, and gastritis. It may also behavior (similar to acuteingestion), and metabolism (weight loss). Chronic exposure via inhalation may cause asthma and/or bronchitis with cough,phlegm, and/or shortness of breath . It may also affect the blood (decreased leukocyte count), and urinary system (kidneys).Repeated or prolonged skin contact may cause thickening, blackening, and cracking of the skin.
Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal:Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT Classification:
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CLASS 3: Flammable liquid. Class 8: Corrosive material
Identification: : Acetic Acid, Glacial UNNA: 2789 PG: II
Special Provisions for Transport: Not available.
Section 15: Other Regulatory Information
Federal and State Regulations:New York release reporting list: Acetic acid Rhode Island RTK hazardous substances: Acetic acid Pennsylvania RTK: Aceticacid Florida: Acetic acid Minnesota: Acetic acid Massachusetts RTK: Acetic acid New Jersey: Acetic acid California Director'sList of Hazardous Subtances (8 CCR 339): Acetic acid TSCA 8(b) inventory: Acetic acid CERCLA: Hazardous substances.:Acetic acid: 5000 lbs. (2268 kg)
Other Regulations:OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This product is on theEuropean Inventory of Existing Commercial Chemical Substances.
Other Classifications:
WHMIS (Canada):CLASS B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C (200°F). CLASS E: Corrosive liquid.
DSCL (EEC):R10- Flammable. R35- Causes severe burns. S23- Do not breathe gas/fumes/vapour/spray [***] S26- In case of contact witheyes, rinse immediately with plenty of water and seek medical advice. S45- In case of accident or if you feel unwell, seekmedical advice immediately (show the label where possible).
HMIS (U.S.A.):
Health Hazard: 3
Fire Hazard: 2
Reactivity: 0
Personal Protection: H
National Fire Protection Association (U.S.A.):
Health: 3
Flammability: 2
Reactivity: 0
Specific hazard:
Protective Equipment:Gloves (impervious). Synthetic apron. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wearappropriate respirator when ventilation is inadequate. Splash goggles.
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/09/2005 03:35 PM
Last Updated: 05/21/2013 12:00 PM
The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume
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no liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.
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Material Safety Data SheetAcetic anhydride MSDS
Section 1: Chemical Product and Company Identification
Product Name: Acetic anhydride
Catalog Codes: SLA1693
CAS#: 108-24-7
RTECS: AK1925000
TSCA: TSCA 8(b) inventory: Acetic anhydride
CI#: Not available.
Synonym:
Chemical Formula: (CH3CO)2)
Contact Information:
Sciencelab.com, Inc.14025 Smith Rd.Houston, Texas 77396
US Sales: 1-800-901-7247International Sales: 1-281-441-4400
For non-emergency assistance, call: 1-281-441-4400
Section 2: Composition and Information on Ingredients
Composition:
Name CAS # % by Weight
Acetic anhydride 108-24-7 100
Toxicological Data on Ingredients: Acetic anhydride: ORAL (LD50): Acute: 1780 mg/kg [Rat]. DERMAL (LD50): Acute: 4000mg/kg [Rabbit].
Section 3: Hazards Identification
Potential Acute Health Effects:Extremely hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Very hazardous incase of skin contact (corrosive). Hazardous in case of skin contact (permeator). Liquid or spray mist may produce tissuedamage particularly on mucous membranes of eyes, mouth and respiratory tract. Skin contact may produce burns. Inhalationof the spray mist may produce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath.Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching,scaling, reddening, or, occasionally, blistering.
Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to lungs, mucous membranes. Repeated or prolongedexposure to the substance can produce target organs damage. Repeated or prolonged contact with spray mist may producechronic eye irritation and severe skin irritation. Repeated or prolonged exposure to spray mist may produce respiratory tractirritation leading to frequent attacks of bronchial infection.
Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Get medical attention immediately.
Skin Contact:In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothingand shoes. Cover the irritated skin with an emollient. Wash clothing before reuse. Thoroughly clean shoes before reuse. Getmedical attention immediately.
Serious Skin Contact:Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medicalattention.
Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention immediately.
Serious Inhalation:Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Ifbreathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. WARNING: It maybe hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled material is toxic, infectious orcorrosive. Seek immediate medical attention.
Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar,tie, belt or waistband.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: Flammable.
Auto-Ignition Temperature: 316°C (600.8°F)
Flash Points: CLOSED CUP: 49°C (120.2°F). OPEN CUP: 51°C (123.8°F).
Flammable Limits: LOWER: 2.7% UPPER: 10.3%
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances: Flammable in presence of heat.
Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available.
Fire Fighting Media and Instructions:Flammable liquid. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use alcohol foam, water spray or fog. Coolcontaining vessels with water jet in order to prevent pressure build-up, autoignition or explosion.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
Section 6: Accidental Release Measures
Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal.
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Large Spill:Flammable liquid. Corrosive liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorbwith DRY earth, sand or other non-combustible material. Do not get water inside container. Do not touch spilled material.Use water spray curtain to divert vapor drift. Prevent entry into sewers, basements or confined areas; dike if needed. Callfor assistance on disposal. Be careful that the product is not present at a concentration level above TLV. Check TLV on theMSDS and with local authorities.
Section 7: Handling and Storage
Precautions:Keep container dry. Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material.Do not ingest. Do not breathe gas/fumes/ vapor/spray. Never add water to this product. In case of insufficient ventilation,wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoidcontact with skin and eyes.
Storage:Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed andsealed until ready for use. Avoid all possible sources of ignition (spark or flame).
Section 8: Exposure Controls/Personal Protection
Engineering Controls:Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respectivethreshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.
Personal Protection:Face shield. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Boots.
Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.
Exposure Limits:TWA: 5 TWA: 20 Consult local authorities for acceptable exposure limits.
Section 9: Physical and Chemical Properties
Physical state and appearance: Liquid.
Odor: Strong.
Taste: Strong.
Molecular Weight: 102.09 g/mole
Color: Light.
pH (1% soln/water): Not available.
Boiling Point: 139.9°C (283.8°F)
Melting Point: -73.1 (-99.6°F)
Critical Temperature: Not available.
Specific Gravity: 1.08 (Water = 1)
Vapor Pressure: 0.5 kPa (@ 20°C)
Vapor Density: 3.52 (Air = 1)
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Volatility: Not available.
Odor Threshold: 0.1 ppm
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
Solubility: Not available.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Not available.
Incompatibility with various substances: Not available.
Corrosivity: Not available.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Dermal contact. Eye contact. Inhalation. Ingestion.
Toxicity to Animals:WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE. Acute oraltoxicity (LD50): 1780 mg/kg [Rat]. Acute dermal toxicity (LD50): 4000 mg/kg [Rabbit]. Acute toxicity of the vapor (LC50): 10004 hours [Rat].
Chronic Effects on Humans: Causes damage to the following organs: lungs, mucous membranes.
Other Toxic Effects on Humans:Extremely hazardous in case of skin contact (irritant), of ingestion, . Very hazardous in case of skin contact (corrosive).Hazardous in case of skin contact (permeator), of eye contact (corrosive), of inhalation (lung corrosive).
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Not available.
Special Remarks on other Toxic Effects on Humans: Not available.
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.
Special Remarks on the Products of Biodegradation: Not available.
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Section 13: Disposal Considerations
Waste Disposal:
Section 14: Transport Information
DOT Classification: Class 8: Corrosive material
Identification: : Acetic Anhydride UNNA: UN1715 PG: II
Special Provisions for Transport: Not available.
Section 15: Other Regulatory Information
Federal and State Regulations:Pennsylvania RTK: Acetic anhydride Massachusetts RTK: Acetic anhydride TSCA 8(b) inventory: Acetic anhydride CERCLA:Hazardous substances.: Acetic anhydride
Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
Other Classifications:
WHMIS (Canada):CLASS B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C (200°F). CLASS E: Corrosive liquid.
DSCL (EEC):R10- Flammable. R20/22- Harmful by inhalation and if swallowed. R34- Causes burns.
HMIS (U.S.A.):
Health Hazard: 3
Fire Hazard: 2
Reactivity: 0
Personal Protection:
National Fire Protection Association (U.S.A.):
Health: 3
Flammability: 2
Reactivity: 1
Specific hazard:
Protective Equipment:Gloves. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respiratorwhen ventilation is inadequate. Face shield.
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/10/2005 08:13 PM
Last Updated: 05/21/2013 12:00 PM
The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume
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no liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.
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Material Safety Data SheetAcetone MSDS
Section 1: Chemical Product and Company Identification
Potential Acute Health Effects:Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Slightly hazardous in case ofskin contact (permeator).
Potential Chronic Health Effects:CARCINOGENIC EFFECTS: A4 (Not classifiable for human or animal.) by ACGIH. MUTAGENIC EFFECTS: Not available.TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female,Reproductive system/toxin/male [SUSPECTED]. The substance is toxic to central nervous system (CNS). The substance maybe toxic to kidneys, the reproductive system, liver, skin. Repeated or prolonged exposure to the substance can produce targetorgans damage.
Eye Contact:Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Cold water may be used. Get medical attention.
Skin Contact:In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminatedclothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medicalattention.
Serious Skin Contact:Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention.
Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention if symptoms appear.
Serious Inhalation:Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Ifbreathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medicalattention.
Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances: Highly flammable in presence of open flames and sparks, of heat.
Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Slightly explosive in presence of openflames and sparks, of oxidizing materials, of acids.
Fire Fighting Media and Instructions:Flammable liquid, soluble or dispersed in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use alcohol foam,water spray or fog.
Special Remarks on Fire Hazards: Vapor may travel considerable distance to source of ignition and flash back.
Small Spill:Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.
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Large Spill:Flammable liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth,sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers, basements or confinedareas; dike if needed. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDSand with local authorities.
Section 7: Handling and Storage
Precautions:Keep locked up.. Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Donot ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of insufficient ventilation, wearsuitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoidcontact with skin and eyes. Keep away from incompatibles such as oxidizing agents, reducing agents, acids, alkalis.
Storage:Store in a segregated and approved area (flammables area) . Keep container in a cool, well-ventilated area. Keep containertightly closed and sealed until ready for use. Keep away from direct sunlight and heat and avoid all possible sources of ignition(spark or flame).
Section 8: Exposure Controls/Personal Protection
Engineering Controls:Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respectivethreshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.
Personal Protection:Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.
Water/Oil Dist. Coeff.: The product is more soluble in water; log(oil/water) = -0.2
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water.
Solubility: Easily soluble in cold water, hot water.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat, ignition sources, exposure to moisture, air, or water, incompatible materials.
Incompatibility with various substances: Reactive with oxidizing agents, reducing agents, acids, alkalis.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation.
Toxicity to Animals:WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE. Acute oraltoxicity (LD50): 3000 mg/kg [Mouse]. Acute toxicity of the vapor (LC50): 44000 mg/m3 4 hours [Mouse].
Chronic Effects on Humans:CARCINOGENIC EFFECTS: A4 (Not classifiable for human or animal.) by ACGIH. DEVELOPMENTAL TOXICITY: ClassifiedReproductive system/toxin/female, Reproductive system/toxin/male [SUSPECTED]. Causes damage to the following organs:central nervous system (CNS). May cause damage to the following organs: kidneys, the reproductive system, liver, skin.
Other Toxic Effects on Humans:Hazardous in case of skin contact (irritant), of ingestion, of inhalation. Slightly hazardous in case of skin contact (permeator).
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans:May affect genetic material (mutagenicity) based on studies with yeast (S. cerevisiae), bacteria, and hamster fibroblast cells.May cause reproductive effects (fertility) based upon animal studies. May contain trace amounts of benzene and formaldehydewhich may cancer and birth defects. Human: passes the placental barrier.
Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: May cause skin irritation. May be harmful if absorbed through the skin. Eyes: Causeseye irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. Inhalation:Inhalation at high concentrations affects the sense organs, brain and causes respiratory tract irritation. It also may affect theCentral Nervous System (behavior) characterized by dizzness, drowsiness, confusion, headache, muscle weakeness, andpossibly motor incoordination, speech abnormalities, narcotic effects and coma. Inhalation may also affect the gastrointestinaltract (nausea, vomiting). Ingestion: May cause irritation of the digestive (gastrointestinal) tract (nausea, vomiting). It may also
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affect the Central Nevous System (behavior), characterized by depression, fatigue, excitement, stupor, coma, headache,altered sleep time, ataxia, tremors as well at the blood, liver, and urinary system (kidney, bladder, ureter) and endocrinesystem. May also have musculoskeletal effects. Chronic Potential Health Effects: Skin: May cause dermatitis. Eyes: Eyeirritation.
Section 12: Ecological Information
Ecotoxicity:Ecotoxicity in water (LC50): 5540 mg/l 96 hours [Trout]. 8300 mg/l 96 hours [Bluegill]. 7500 mg/l 96 hours [Fatthead Minnow].0.1 ppm any hours [Water flea].
BOD5 and COD: Not available.
Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal:Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT Classification: CLASS 3: Flammable liquid.
Identification: : Acetone UNNA: 1090 PG: II
Special Provisions for Transport: Not available.
Section 15: Other Regulatory Information
Federal and State Regulations:California prop. 65: This product contains the following ingredients for which the State of California has found to causereproductive harm (male) which would require a warning under the statute: Benzene California prop. 65: This product containsthe following ingredients for which the State of California has found to cause birth defects which would require a warning underthe statute: Benzene California prop. 65: This product contains the following ingredients for which the State of California hasfound to cause cancer which would require a warning under the statute: Benzene, Formaldehyde Connecticut hazardousmaterial survey.: Acetone Illinois toxic substances disclosure to employee act: Acetone Illinois chemical safety act: AcetoneNew York release reporting list: Acetone Rhode Island RTK hazardous substances: Acetone Pennsylvania RTK: AcetoneFlorida: Acetone Minnesota: Acetone Massachusetts RTK: Acetone Massachusetts spill list: Acetone New Jersey: AcetoneNew Jersey spill list: Acetone Louisiana spill reporting: Acetone California List of Hazardous Substances (8 CCR 339):Acetone TSCA 8(b) inventory: Acetone TSCA 4(a) final test rules: Acetone TSCA 8(a) IUR: Acetone
Other Regulations:OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This product is on theEuropean Inventory of Existing Commercial Chemical Substances.
Other Classifications:
WHMIS (Canada):CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F). CLASS D-2B: Material causing other toxic effects(TOXIC).
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DSCL (EEC):R11- Highly flammable. R36- Irritating to eyes. S9- Keep container in a well-ventilated place. S16- Keep away from sources ofignition - No smoking. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
HMIS (U.S.A.):
Health Hazard: 2
Fire Hazard: 3
Reactivity: 0
Personal Protection: h
National Fire Protection Association (U.S.A.):
Health: 1
Flammability: 3
Reactivity: 0
Specific hazard:
Protective Equipment:Gloves. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respiratorwhen ventilation is inadequate. Splash goggles.
The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assumeno liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.
Material Safety Data Sheet (Activated Carbon)
415 Huguenot Street New Rochelle, NY 10801 Phone: (914) 654-6800 Fax: (914) 654-6899
DATE PREPARED: 6/18/2009 REVISION NUMBER: 6/18/2009 EMERGENCY NUMBER: CHEMTREC: 1-800-424-9300
SECTION 1 – PRODUCT AND COMPANY INFORMATION
PRODUCT NAME Activated Carbon SYNONYM Charcoal, Activated FORMULA C CAS NUMBER 7440-44-0
SECTION 2 – COMPOSITON/INFORMATION ON INGREDIENTS
PRODUCT NAME CAS NUMBER PURITY Activated Carbon 7440-44-0 90 - 100%
SECTION 3- HAZARDS IDENTIFICATION Emergency Overview CAUTION! ACTIVATED CARBON AFFECTS THE RESPIRATORY AND CARDIOVASCULAR SYSTEMS. SAF-T-DATA(tm) Ratings (Provided here for your convenience) Health Rating: 2 - Moderate Flammability Rating: 1 - Slight Reactivity Rating: 1 - Slight Contact Rating: 1 - Slight Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES Storage Color Code: Green (General Storage) Potential Health Effects Inhalation: No adverse effects expected. May cause mild irritation to the respiratory tract. Ingestion: No adverse effects expected. May cause mild irritation to the gastrointestinal tract. Skin Contact: Not expected to be a health hazard from skin exposure. May cause mild irritation and redness. Eye Contact: No adverse effects expected. May cause mild irritation, possible reddening. Chronic Exposure: Prolonged inhalation of excessive dust may produce pulmonary disorders. Aggravation of Pre-existing Conditions: No information found.
Material Safety Data Sheet (Activated Carbon)
SECTION 4 – FIRST AID MEASURES Inhalation: Remove to fresh air. Get medical attention for any breathing difficulty. Ingestion: Give several glasses of water to drink to dilute. If large amounts were swallowed, get medical advice. Skin Contact: Not expected to require first aid measures. Wash exposed area with soap and water. Get medical advice if irritation develops. Eye Contact: Wash thoroughly with running water. Get medical advice if irritation develops.
SECTION 5 – FIRE FIGHTING MEASURES Fire: As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source. Activated carbon is difficult to ignite and tends to burn slowly (smolder) without producing smoke or flame.
Wet activated carbon depletes oxygen from the air. Materials allowed to smolder for long periods in enclosed spaces, may produce amounts of carbon monoxide which may reach the lower explosive limit for carbon monoxide of 12.5% in air.
Contact with strong oxidizers such as ozone or liquid oxygen may cause rapid combustion.
Explosion: Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. Minimum explosible concentration 0.140 g/l.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
SECTION 6 – ACCIDENTAL RELEASE MEASURES
Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container. Warning! Spent product may have absorbed hazardous materials.
Material Safety Data Sheet (Activated Carbon)
SECTION 7- HANDLING AND STORAGE
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Keep away from moisture and oxidizers. Avoid dust dispersal. Wet activated carbon depletes oxygen from the air and therefore dangerously low levels of oxygen may be encountered in confined spaces. Work procedures for potentially low oxygen areas should be followed. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
SECTION 8 - EXPOSURE CONTROLS/ PERSONAL PROTECTION
- ACGIH Threshold Limit Values (TLVs): graphite, all forms except graphite fibers: 2 mg/m3 (TWA).
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits.
Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the dust or mist is apparent, a half-face dust/mist respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres. Skin Protection: Wear protective gloves and clean body-covering clothing. Eye Protection: Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
SECTION 9 – PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Black powder.
Odor: Odorless.
Solubility: Insoluble in water.
Specific Gravity: 1.8 - 2.1
pH: 5.0-10.0
% Volatiles by volume @ 21C (70F): 0
Boiling Point: Sublimes.
Material Safety Data Sheet (Activated Carbon)
Melting Point: 3550C (6422F)
Vapor Density (Air=1): 0.4
Vapor Pressure (mm Hg): 1 @ 3586C (6487F)
Evaporation Rate (BuAc=1): No information found.
SECTION 10 – STABILITY AND REACTIVITY DATA
Stability: Stable under ordinary conditions of use and storage. Hazardous Decomposition Products: Involvement in a fire causes formation of carbon dioxide and carbon monoxide. Hazardous Polymerization: Will not occur. Incompatibilities: Strong oxidizers such as ozone, liquid oxygen, chlorine, permanganate, etc. may result in rapid combustion. Avoid contact with strong acids. Conditions to Avoid: Moisture and incompatibles.
SECTION 11 – TOXICOLOGICAL INFORMATION
Investigated as a reproductive effector. --------------------------------\Cancer Lists\------------------------------------------------------ ---NTP Carcinogen--- Ingredient Known Anticipated IARC Category ------------------------------------ ----- ----------- ------------- Steam Activated Carbon (7440-44-0) No No None
SECTION 12 – ECOLOGICAL INFORMATION
Environmental Fate: No information found.
Environmental Toxicity: No information found.
SECTION 13 – DISPOSAL CONSIDERATION
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Material Safety Data Sheet (Activated Carbon)
SECTION 14 - TRANSPORTATION DATA
Not regulated.
SECTION 15 – REGULATORY INFORMATION
--------\Chemical Inventory Status - Part 1\--------------------------------- Ingredient TSCA EC Japan Australia ----------------------------------------------- ---- --- ----- --------- Steam Activated Carbon (7440-44-0) Yes Yes No Yes ---------\Chemical Inventory Status - Part 2\--------------------------------- --Canada-- Ingredient Korea DSL NDSL Phil. ----------------------------------------------- ----- --- ---- ----- Steam Activated Carbon (7440-44-0) Yes Yes No Yes ----------\Federal, State & International Regulations - Part 1\---------------- -SARA 302- ------SARA 313------ Ingredient RQ TPQ List Chemical Catg. ----------------------------------------- --- ----- ---- -------------- Steam Activated Carbon (7440-44-0) No No No No --------\Federal, State & International Regulations - Part 2\---------------- -RCRA- -TSCA- Ingredient CERCLA 261.33 8(d) ----------------------------------------- ------ ------ ------ Steam Activated Carbon (7440-44-0) No No No Chemical Weapons Convention: No TSCA 12(b): No CDTA: No SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No Reactivity: No (Pure / Solid)
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS: This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
Label Hazard Warning: CAUTION! ACTIVATED CARBON AFFECTS THE RESPIRATORY AND CARDIOVASCULAR SYSTEMS.
Material Safety Data Sheet (Activated Carbon)
Label Precautions: Avoid contact with eyes, skin and clothing. Avoid breathing dust. Keep container closed. Use with adequate ventilation. Wash thoroughly after handling. Label First Aid: If inhaled, remove to fresh air. Get medical attention for any breathing difficulty. Product Use: Laboratory Reagent. Disclaimer The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product.
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Material Safety Data SheetCharcoal, Activated, Powder MSDS
Section 1: Chemical Product and Company Identification
Product Name: Charcoal, Activated, Powder
Catalog Codes: SLC3982, SLC1189
CAS#: 7440-44-0
RTECS: FL7243500
TSCA: TSCA 8(b) inventory: Charcoal, Activated
CI#: Not available.
Synonym:
Chemical Name: Charcoal, Activated
Chemical Formula: C
Contact Information:
Sciencelab.com, Inc.14025 Smith Rd.Houston, Texas 77396
US Sales: 1-800-901-7247International Sales: 1-281-441-4400
For non-emergency assistance, call: 1-281-441-4400
Section 2: Composition and Information on Ingredients
Composition:
Name CAS # % by Weight
Charcoal, Activated 7440-44-0 100
Toxicological Data on Ingredients: Charcoal, Activated LD50: Not available. LC50: Not available.
Section 3: Hazards Identification
Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, ofinhalation.
Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to mucous membranes. The substance may be toxic tolungs. Repeated or prolonged exposure to the substance can produce target organs damage.
Section 4: First Aid Measures
Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Get medical attention if irritation occurs.
Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Serious Skin Contact: Not available.
Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention.
Serious Inhalation:Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Seekmedical attention.
Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar,tie, belt or waistband.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: Flammable.
Auto-Ignition Temperature: 452°C (845.6°F)
Flash Points: Not available.
Flammable Limits: Not available.
Products of Combustion: Not available.
Fire Hazards in Presence of Various Substances:Highly flammable in presence of open flames and sparks, of heat. Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available.
Fire Fighting Media and Instructions:Flammable solid. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray or fog. Cool containing vesselswith water jet in order to prevent pressure build-up, autoignition or explosion.
Special Remarks on Fire Hazards:Flammable/combustible material. May be ignited by friction, heat, sparks, or flames. May reignite after fire is extinguished.Freshly prepared material may heat spontaneously in air, and presence of water accelerates this.
Special Remarks on Explosion Hazards:Material in powder form, capable of creating a dust explosion (forming explosive mixtures in air) when exposed to heat, flame,or ammonium nitrate + heat. ammonium tetrachloride at 240 C, bromates, Ca(OCl)2, chlorates, Cl2, (Cl2 + Cr(OCl)2), ClO, F2,iodates, IO5, (Pb(NO3)2, HgNO3, HNO3, (oils + air), (potassium + air), Na2S, Zn(NO3)2.
Section 6: Accidental Release Measures
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill:Spontaneously combustible solid. Stop leak if without risk. Absorb with an inert material and put the spilled material in anappropriate waste disposal. Obtain advice on use of water as spilled material may react with it. Do not touch spilled material.Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition sources. Cover with wet earth,sand or other non-combustible material. Call for assistance on disposal. Be careful that the product is not present at aconcentration level above TLV. Check TLV on the MSDS and with local authorities.
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Section 7: Handling and Storage
Precautions:Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not breathe dust.Keep away from incompatibles such as oxidizing agents, metals, acids.
Storage:Store in a segregated and approved area. Keep in a cool and ventilated area away from combustible materials. Keepcontainer in a cool, well-ventilated area. Keep container tightly closed and sealed until ready for use. Avoid all possiblesources of ignition (spark or flame).
Section 8: Exposure Controls/Personal Protection
Engineering Controls:Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommendedexposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminantsbelow the exposure limit.
Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.Gloves.
Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.
Physical state and appearance: Solid. (Solid powder.)
Odor: Odorless.
Taste: Not available.
Molecular Weight: 12.01 g/mole
Color: Black
pH (1% soln/water): Not applicable.
Boiling Point: Not available.
Melting Point: 3500°C (6332°F)
Critical Temperature: 6810°C (12290°F)
Specific Gravity: 3.51 (Water = 1)
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
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Dispersion Properties: Not available.
Solubility: Insoluble in cold water, hot water.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Heat, ignition sources (flames, sparks), air,incompatible materials
Incompatibility with various substances: Reactive with oxidizing agents, metals, acids.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity:Incompatible with air, unsaturated oils, 2-Nitrobenzaldehyde, strong oxidizers such as fluorine, chlorine trifluoride, andpotassium peroxide.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Inhalation. Ingestion.
Toxicity to Animals:LD50: Not available. LC50: Not available.
Chronic Effects on Humans:Causes damage to the following organs: mucous membranes. May cause damage to the following organs: lungs.
Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: May cause adverse reproductive effects.
Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: May cause eye irritation. Inhalation: May causerespiratory tract irritation. Ingestion: May cause aspiration pneumonitis, vomiting, decreased gastrointestinal transit time,gastrointestinal obstruction, constipation, a charcoal-containing empyema, intestinal perforation, charcoal deposits in theesophageal and gastric mucosa, rectal ulcer. Chronic Potential Health Effects: Skin: Chronic skin exposure can result inclogging of hair follicles, rendering them black. Inhalation: Chronic inhalation can cause carbon particles to accumulate in thelungs. It may cause a pneumoconiosis called "Black Lung Disease" or "Coal Workers Pneumoconiosis". This is seen in coalworkers, but no evidence has been found for the equivalent with occupational exposure to activated carbon (charcoal).
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
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Section 13: Disposal Considerations
Waste Disposal:Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT Classification: CLASS 4.2: Spontaneously combustible substance.
Identification: : Carbon, activated UNNA: 1362 PG: III
Special Provisions for Transport: Not available.
Section 15: Other Regulatory Information
Federal and State Regulations:Rhode Island RTK hazardous substances: Charcoal, Activated TSCA 8(b) inventory: Charcoal, Activated
Other Regulations:OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This product is on theEuropean Inventory of Existing Commercial Chemical Substances.
Other Classifications:
WHMIS (Canada): Not controlled under WHMIS (Canada).
DSCL (EEC):This product is not classified according to the EU regulations. Not applicable.
HMIS (U.S.A.):
Health Hazard: 1
Fire Hazard: 3
Reactivity: 0
Personal Protection: E
National Fire Protection Association (U.S.A.):
Health: 1
Flammability: 3
Reactivity: 0
Specific hazard:
Protective Equipment:Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses.
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/09/2005 04:37 PM
Last Updated: 05/21/2013 12:00 PM
The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume
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no liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 1/17
SDS_GB - 000010021772
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Chemical formula: NH3 INDEX No. 007-001-00-5 CAS-No. 7664-41-7 EC No. 231-635-3 REACH Registration No. 01-2119488876-14
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses: Industrial and professional. Perform risk assessment prior to use. Casting operations. Explosives manufacture & use. Freezing, chilling, and packaging of foodstuffs. Manufacturing of fertilisers and nitric acid. Production of plastics. Refrigerant. Use for electronic component manufacture. Use of gas to manufacture pharmaceutical products. Using gas alone or in mixtures for the calibration of analysis equipment. Using gas as feedstock in chemical processes. Using gas for metal treatment. Washing of textiles or metal parts. Water treatment. Use in laboratories
Uses advised against Consumer use.
1.3 Details of the supplier of the safety data sheet
Supplier BOC Priestley Road, Worsley M28 2UT Manchester
Category 2 H411: Toxic to aquatic life with long lasting effects.
2.2 Label Elements
Contains: ammonia, anhydrous
Signal Words: Danger
Hazard Statement(s): H221: Flammable gas. H280: Contains gas under pressure; may explode if heated. H314: Causes severe skin burns and eye damage. H331: Toxic if inhaled. H410: Very toxic to aquatic life with long lasting effects.
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 3/17
SDS_GB - 000010021772
Precautionary Statement
Prevention: P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P260: Do not breathe gas/vapours. P273: Avoid release to the environment. P280: Wear protective gloves/protective clothing/eye protection/face protection.
Response: P303+P361+P353+P315: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower. Get immediate medical advice/attention. P304+P340+P315: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Get immediate medical advice/attention. P305+P351+P338+P315: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get immediate medical advice/attention. P377: Leaking gas fire: Do not extinguish, unless leak can be stopped safely. P381: Eliminate all ignition sources if safe to do so.
Storage: P403: Store in a well-ventilated place. P405: Store locked up.
Disposal: None.
Supplemental label information
EUH071: Corrosive to the respiratory tract.
2.3 Other hazards: Contact with evaporating liquid may cause frostbite or freezing of skin.
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 4/17
SDS_GB - 000010021772
SECTION 3: Composition/information on ingredients
3.1 Substances
Chemical name ammonia, anhydrous INDEX No.: 007-001-00-5 CAS-No.: 7664-41-7 EC No.: 231-635-3 REACH Registration No.: 01-2119488876-14 Purity: 100%
The purity of the substance in this section is used for classification only, and does not represent the actual purity of the substance as supplied, for which other documentation should be consulted.
General: Remove victim to uncontaminated area wearing self contained breathing
apparatus. Keep victim warm and rested. Call a doctor. Apply artificial respiration if breathing stopped.
4.1 Description of first aid measures
Inhalation: Remove victim to uncontaminated area wearing self contained breathing apparatus. Keep victim warm and rested. Call a doctor. Apply artificial respiration if breathing stopped.
Eye contact: Rinse the eye with water immediately. Remove contact lenses, if present and easy to do. Continue rinsing. Flush thoroughly with water for at least 15 minutes. Get immediate medical assistance. If medical assistance is not immediately available, flush an additional 15 minutes.
Skin Contact: Immediately flush with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention immediately. Contact with evaporating liquid may cause frostbite or freezing of skin.
Ingestion: Ingestion is not considered a potential route of exposure.
4.2 Most important symptoms and
effects, both acute and
delayed:
Causes severe skin burns and eye damage. Contact with liquefied gas can cause damage (frostbite) due to rapid evaporative cooling. May be fatal if inhaled.
4.3 Indication of any immediate medical attention and special treatment needed
Hazards: Causes severe skin burns and eye damage. Contact with liquefied gas can cause damage (frostbite) due to rapid evaporative cooling. May be fatal if inhaled.
Treatment: Thaw frosted parts with lukewarm water. Do not rub affected area. Get immediate medical advice/attention. Treat with a corticosteroid spray as soon as possible after inhalation.
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 5/17
SDS_GB - 000010021772
SECTION 5: Firefighting Measures
General Fire Hazards: Heat may cause the containers to explode.
5.1 Extinguishing media
Suitable extinguishing media: Use water spray to reduce vapours or divert vapour cloud drift. Water Spray or Fog. Dry powder. Foam.
Unsuitable extinguishing
media:
Carbon dioxide. Do not use water jet, as this may cause corrosive liquid to splash.
5.2 Special hazards arising from the
substance or mixture: Fire or excessive heat may produce hazardous decomposition products. Fire or excessive heat may produce hazardous decomposition products.
Hazardous Combustion Products: If involved in a fire the following toxic and/or corrosive fumes may be produced
by thermal decomposition: Nitrogen monoxide ; nitrogen dioxide
5.3 Advice for firefighters
Special fire fighting
procedures:
In case of fire: Stop leak if safe to do so. Use of water may result in the formation of very toxic aqueous solutions. Keep run-off water out of sewers and water sources. Dyke for water control. Continue water spray from protected position until container stays cool. Use extinguishants to contain the fire. Isolate the source of the fire or let it burn out.
Special protective equipment
for firefighters:
Gas tight chemically protective clothing (Type 1) in combination with self contained breathing apparatus. Guideline: EN 943-2 Protective clothing against liquid and gaseous chemicals, aerosols and solid particles. Performance requirements for gas-tight (Type 1) chemical protective suits for emergency teams (ET)
SECTION 6: Accidental Release Measures
6.1 Personal precautions,
protective equipment and
emergency procedures:
Evacuate area. Provide adequate ventilation. Consider the risk of potentially explosive atmospheres . Eliminate all ignition sources if safe to do so. Monitor the concentration of the released product. Prevent from entering sewers, basements and workpits, or any place where its accumulation can be dangerous. Wear self-contained breathing apparatus when entering area unless atmosphere is proved to be safe. EN 137 Respiratory protective devices - Self-contained open-circuit compressed air breathing apparatus with full face mask - Requirements, testing, marking.
6.2 Environmental Precautions: Prevent further leakage or spillage if safe to do so. Reduce vapour with fog or fine
water spray. Keep run-off water out of sewers and water sources. Dyke for water control.
6.3 Methods and material for
containment and cleaning up:
Provide adequate ventilation. Eliminate sources of ignition. Wash contaminated equipment or sites of leaks with copious quantities of water.
6.4 Reference to other sections: Refer to sections 8 and 13.
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 6/17
SDS_GB - 000010021772
SECTION 7: Handling and Storage:
7.1 Precautions for safe handling: Only experienced and properly instructed persons should handle gases under pressure. Avoid exposure - obtain special instructions before use. Use only properly specified equipment which is suitable for this product, its supply pressure and temperature. Purge system with dry inert gas (e.g. helium or nitrogen) before gas is introduced and when system is placed out of service. Purge air from system before introducing gas. Containers, which contain or have contained flammable or explosive substances, must not be inerted with liquid carbon dioxide. Assess the risk of a potentially explosive atmosphere and the need for suitable equipment i.e. explosion-proof. Take precautionary measures against static discharges. Keep away from ignition sources (including static discharges). Provide electrical earthing of equipment and electrical equipment usable in explosive atmospheres. Use only non-sparking tools. Installation of a cross purge assembly between the container and the regulator is recommended. Excess pressure must be vented through an appropriate scrubber system. Refer to supplier's handling instructions. The substance must be handled in accordance with good industrial hygiene and safety procedures. Ensure the complete system has been (or is regularly) checked for leaks before use. Protect containers from physical damage; do not drag, roll, slide or drop. Do not remove or deface labels provided by the supplier for the identification of the container contents. When moving containers, even for short distances, use appropriate equipment eg. trolley, hand truck, fork truck etc. Secure cylinders in an upright position at all times, close all valves when not in use. Provide adequate ventilation. Suck back of water into the container must be prevented. Do not allow backfeed into the container. Avoid suckback of water, acid and alkalis. Keep container below 50°C in a well ventilated place. Observe all regulations and local requirements regarding storage of containers. When using do not eat, drink or smoke. Store in accordance with local/regional/national/international regulations. Never use direct flame or electrical heating devices to raise the pressure of a container. Leave valve protection caps in place until the container has been secured against either a wall or bench or placed in a container stand and is ready for use. Damaged valves should be reported immediately to the supplier Close container valve after each use and when empty, even if still connected to equipment. Never attempt to repair or modify container valves or safety relief devices. Replace valve outlet caps or plugs and container caps where supplied as soon as container is disconnected from equipment. Keep container valve outlets clean and free from contaminates particularly oil and water. If user experiences any difficulty operating container valve discontinue use and contact supplier. Never attempt to transfer gases from one container to another. Container valve guards or caps should be in place.
7.2 Conditions for safe storage,
including any incompatibilities:
All electrical equipment in the storage areas should be compatible with the risk of a potentially explosive atmosphere. Segregate from oxidant gases and other oxidants being stored. Containers should not be stored in conditions likely to encourage corrosion. Stored containers should be periodically checked for general conditions and leakage. Keep away from food, drink and animal feeding stuffs. Container valve guards or caps should be in place. Store containers in location free from fire risk and away from sources of heat and ignition. Keep away from combustible material.
Consider a work permit system e.g. for maintenance activities. Ensure adequate air ventilation. Provide adequate general and local exhaust ventilation. Keep concentrations well below occupational exposure limits. Gas detectors should be used when toxic quantities may be released. Gas detectors should be used when quantities of flammable gases or vapours may be released. Systems under pressure should be regularly checked for leakages. Product to be handled in a closed system and under strictly controlled conditions. Use only permanent leak tight installations (e.g. welded pipes). Take precautionary measures against static discharges. Do not eat, drink or smoke when using the product.
Individual protection measures, such as personal protective equipment
General information: A risk assessment should be conducted and documented in each work area to assess the risks related to the use of the product and to select the PPE that matches the relevant risk. The following recommendations should be considered. Keep self contained breathing apparatus readily available for emergency use. Personal protective equipment for the body should be selected based on the task being performed and the risks involved. Protect eyes, face and skin from contact with product. Refer to local regulations for restriction of emissions to the atmosphere. See section 13 for specific methods for waste gas treatment.
Eye/face protection: Safety eyewear, goggles or face-shield to EN166 should be used to avoid
exposure to liquid splashes. Wear eye protection to EN 166 when using gases. Guideline: EN 166 Personal Eye Protection.
Skin protection
Hand Protection: Wear working gloves while handling containers Guideline: EN 388 Protective gloves against mechanical risks. Chemically resistant gloves complying with EN 374 should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. Material: Chloroprene rubber. Break-through time: 30 min Glove thickness: 0.5 mm Guideline: EN 374-1/2/3 Protective gloves against chemicals and micro-organisms. Chemically resistant gloves complying with EN 374 should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. Material: Butyl rubber. Break-through time: 480 min Glove thickness: 0.7 mm Guideline: EN 374-1/2/3 Protective gloves against chemicals and micro-organisms.
Body protection: Wear fire/flame resistant/retardant clothing. Keep suitable chemically resistant
protective clothing readily available for emergency use. Guideline: ISO/TR 2801:2007 Clothing for protection against heat and flame -- General recommendations for selection, care and use of protective clothing.Guideline: EN 943 Protective clothing against liquid and gaseous chemicals, including liquid aerosols and solid particles.
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 9/17
SDS_GB - 000010021772
Other: Wear safety shoes while handling containers Guideline: ISO 20345 Personal protective equipment - Safety footwear.
Respiratory Protection: Reference should be made to European Standard EN 689 for methods for the
assessment of exposure by inhalation to chemical agents and national guidance documents for methods for the determination of hazardous substances. The selection of the Respiratory Protective Device (RPD) must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected RPD. Material: Filter K Guideline: EN 14387 Respiratory protective devices. Gas filter(s) and combined filter(s). Requirements, testing, marking. Guideline: EN 136 Respiratory protective devices. Full face masks. Requirements, testing, marking.
Thermal hazards: No precautionary measures are necessary.
Hygiene measures: Obtain special instructions before use. Specific risk management measures are not
required beyond good industrial hygiene and safety procedures. Do not eat, drink or smoke when using the product.
Environmental exposure
controls:
For waste disposal, see section 13.
SECTION 9: Physical And Chemical Properties
9.1 Information on basic physical and chemical properties
Appearance
Physical state: Gas Form: Liquefied gas Colour: Colourless
Odour: ammoniacal Odour Threshold: Odour threshold is subjective and is inadequate to warn of over
exposure. pH: If dissolved in water pH-value will be affected. Melting Point: -77.7 °C Boiling Point: -33.35 °C Sublimation Point: not applicable. Critical Temp. (°C): 132.0 °C Flash Point: Not applicable to gases and gas mixtures. Evaporation Rate: Not applicable to gases and gas mixtures. Flammability (solid, gas): Flammable Gas Flammability limit - upper (%): 33.6 %(V)
10.1 Reactivity: No reactivity hazard other than the effects described in sub-section below.
10.2 Chemical Stability: Stable under normal conditions.
10.3 Possibility of Hazardous
Reactions:
Can form a potentially explosive atmosphere in air. May react violently with oxidants.
10.4 Conditions to Avoid: Avoid moisture in the installation. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
10.5 Incompatible Materials: Air and oxidisers. Moisture. For material compatibility see latest version of ISO-11114. Reacts with water to form corrosive alkalis. May react violently with acids.
10.6 Hazardous Decomposition
Products:
Under normal conditions of storage and use, hazardous decomposition products should not be produced. If involved in a fire the following toxic and/or corrosive fumes may be produced by thermal decomposition: The following decomposition products may be produced: Nitrogen monoxide ; nitrogen dioxide
SECTION 11: Toxicological Information
General information: Inhalation of large amounts leads to bronchospasm, laryngeal oedema and pseudomembrane formation.
11.1 Information on toxicological effects
Acute toxicity - Oral
Product Based on available data, the classification criteria are not met.
ammonia, anhydrous
LD 50 (Rat): 350 mg/kg
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 11/17
SDS_GB - 000010021772
Acute toxicity - Dermal
Product Based on available data, the classification criteria are not met.
Acute toxicity - Inhalation
Product Toxic by inhalation. Toxic if inhaled.
ammonia, anhydrous
LC 50 (Rat, 1 h): 4000 ppm
Repeated dose toxicity
ammonia, anhydrous
LOAEL (Rat, Inhalation, 35 - 75 d): 175 mg/m3
Skin Corrosion/Irritation
Product Causes severe burns.
Serious Eye Damage/Eye Irritation
Product Causes serious eye damage.
Respiratory or Skin Sensitisation
Product Based on available data, the classification criteria are not met.
Germ Cell Mutagenicity
Product Based on available data, the classification criteria are not met.
Carcinogenicity
Product Based on available data, the classification criteria are not met.
Reproductive toxicity
Product Based on available data, the classification criteria are not met.
Specific Target Organ Toxicity - Single Exposure
Product Based on available data, the classification criteria are not met.
Specific Target Organ Toxicity - Repeated Exposure
Product Based on available data, the classification criteria are not met.
Aspiration Hazard
Product Not applicable to gases and gas mixtures..
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 12/17
SDS_GB - 000010021772
SECTION 12: Ecological Information
General information: Avoid release to the environment. Product is not allowed to be discharged into ground water or the aquatic environment.
12.1 Toxicity
Acute toxicity
Product Very toxic to aquatic life with long lasting effects.
Acute toxicity - Fish
ammonia, anhydrous
LC 50 (Fish, 96 h): 0.89 mg/l
Acute toxicity - Aquatic Invertebrates
ammonia, anhydrous
LC 50 (Water flea (Daphnia), 48 h): 101 mg/l
Toxicity to microorganisms
ammonia, anhydrous
Depending on local conditions and existing concentrations, disturbances in the biodegradation process of activated sludge are possible.
Toxicity to terrestrial organisms
ammonia, anhydrous
Study not necessary due to exposure considerations.
Chronic toxicity - Fish
ammonia, anhydrous
LOEC (Fish, 73 Days): 0.022 mg/l
Chronic toxicity - Aquatic Invertebrates
ammonia, anhydrous
NOEC (Water flea, 96 hrs): 0.79 mg/l
Toxicity to aquatic plants
ammonia, anhydrous
LC 50 (Algae, algal mat (Algae), 18 Days): 2,700 mg/l
12.2 Persistence and Degradability Product Not applicable to gases and gas mixtures..
Biodegradation
Inorganic The product is not readily biodegradable.
12.3 Bioaccumulative Potential Product The substance has no potential for bioaccumulation.
12.4 Mobility in Soil Product The substance has low mobility in soil.
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 13/17
SDS_GB - 000010021772
ammonia, anhydrous
Henry's Law Constant: 0.09028 MPa (25 °C)
12.5 Results of PBT and vPvB
assessment
Product Not classified as PBT or vPvB.
12.6 Other Adverse Effects:
Other Ecological Information
May cause pH changes in aqueous ecological systems. Depending on local conditions and existing concentrations, disturbances in the biodegradation process of activated sludge are possible.
SECTION 13: Disposal Considerations
13.1 Waste treatment methods
General information: Must not be discharged to atmosphere. Consult supplier for specific recommendations.
Disposal methods: Refer to the EIGA code of practice (Doc.30 "Disposal of Gases", downloadable at http://www.eiga.org) for more guidance on suitable disposal methods. Dispose of container via supplier only. Discharge, treatment, or disposal may be subject to national, state, or local laws. Toxic and corrosive gases formed during combustion should be scrubbed before discharge to atmosphere. Gas may be scrubbed in water. Gas may be scrubbed in sulphuric acid solution.
Emergency Action Code: 2RE 14.4 Packing Group: – 14.5 Environmental hazards: Environmentally Hazardous 14.6 Special precautions for user: –
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 14/17
SDS_GB - 000010021772
RID 14.1 UN Number: UN 1005 14.2 UN Proper Shipping Name AMMONIA, ANHYDROUS 14.3 Transport Hazard Class(es)
Class: 2 Label(s): 2.3, 8
14.4 Packing Group: – 14.5 Environmental hazards: Environmentally Hazardous 14.6 Special precautions for user: –
IMDG
14.1 UN Number: UN 1005 14.2 UN Proper Shipping Name: AMMONIA, ANHYDROUS 14.3 Transport Hazard Class(es)
Class: 2.3 Label(s): 2.3, 8 EmS No.: F-C, S-U
14.3 Packing Group: – 14.5 Environmental hazards: not applicable 14.6 Special precautions for user: –
IATA
14.1 UN Number: UN 1005 14.2 Proper Shipping Name: Ammonia, anhydrous 14.3 Transport Hazard Class(es):
Class: 2.3 Label(s): –
14.4 Packing Group: – 14.5 Environmental hazards: Environmentally Hazardous 14.6 Special precautions for user: –
Other information Passenger and cargo aircraft: Forbidden. Cargo aircraft only: Forbidden.
14.7 Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code: not applicable
Additional identification: Avoid transport on vehicles where the load space is not separated from
the driver's compartment. Ensure vehicle driver is aware of the potential hazards of the load and knows what to do in the event of an accident or an emergency. Before transporting product containers ensure that they are firmly secured. Ensure that the container valve is closed and not leaking. Container valve guards or caps should be in place. Ensure adequate air ventilation.
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture:
EU Regulations
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 15/17
SDS_GB - 000010021772
Directive 96/61/EC: concerning integrated pollution prevention and control (IPPC): Article 15, European
Pollution Emission Registry (EPER):
Chemical name CAS-No. Concentration
ammonia, anhydrous
7664-41-7 100%
Directive 96/82/EC (Seveso II): on the control of major accident hazards involving dangerous substances:
Chemical name CAS-No. Concentration
ammonia, anhydrous
7664-41-7 100%
Directive 98/24/EC on the protection of workers from the risks related to chemical agents at work:
Chemical name CAS-No. Concentration
ammonia, anhydrous
7664-41-7 100%
National Regulations
Dangerous Substances and Explosive Atmospheres Regulations (DSEAR 2002 No. 2776). Management of Health and Safety at Work Regulations (1999 No. 3242). The Regulatory Reform (Fire Safety) Order 2005 (2005 No. 1541). Control of Substances Hazardous to Health Regulations (COSHH, 2002 No. 2677). Provision and Use of Work Equipment Regulations (PUWER, 1998 No. 2306). Personal Protective Equipment Regulations (1992 No. 2966). Control of Major Accident Hazards Regulations (COMAH, 2015 No. 483). Equipment and Protective Systems Intended for Use in Potentially Explosive Atmospheres Regulations (EPS, 1996 No. 192). Pressure Systems Safety Regulations (PSSR, 2000 No. 128). Only products that comply with the food regulations (EC) No. 1333/2008 and (EU) No. 231/2012 and are labelled as such may be used as food additives. This Safety Data Sheet has been produced to comply with Regulation (EU) 453/2010.
15.2 Chemical safety assessment: CSA has been carried out.
SECTION 16: Other Information
Revision Information: Not relevant.
SAFETY DATA SHEET
Ammonia, anhydrous
Issue Date: Last revised date:
16.01.2013 18.12.2015
Version: 1. 0 SDS No.: 000010021772 16/17
SDS_GB - 000010021772
Key literature references and
sources for data:
Various sources of data have been used in the compilation of this SDS, they include but are not exclusive to: Agency for Toxic Substances and Diseases Registry (ATSDR) (http://www.atsdr.cdc.gov/). European Chemical Agency: Guidance on the Compilation of Safety Data Sheets. European Chemical Agency: Information on Registered Substances http://apps.echa.europa.eu/registered/registered-sub.aspx#search European Industrial Gases Association (EIGA) Doc. 169 Classification and Labelling guide. International Programme on Chemical Safety (http://www.inchem.org/) ISO 10156:2010 Gases and gas mixtures - Determination of fire potential and oxidizing ability for the selection of cylinder valve outlets. Matheson Gas Data Book, 7th Edition. National Institute for Standards and Technology (NIST) Standard Reference Database Number 69. The ESIS (European chemical Substances 5 Information System) platform of the former European Chemicals Bureau (ECB) ESIS (http://ecb.jrc.ec.europa.eu/esis/). The European Chemical Industry Council (CEFIC) ERICards. United States of America’s National Library of Medicine’s toxicology data network TOXNET (http://toxnet.nlm.nih.gov/index.html) Threshold Limit Values (TLV) from the American Conference of Governmental Industrial Hygienists (ACGIH). Substance specific information from suppliers. Details given in this document are believed to be correct at the time of publication. EH40 (as amended) Workplace exposure limits.
Wording of the R-phrases and H-statements in sections 2 and 3
H221 Flammable gas. H280 Contains gas under pressure; may explode if heated. H314 Causes severe skin burns and eye damage. H318 Causes serious eye damage. H331 Toxic if inhaled. H400 Very toxic to aquatic life. H411 Toxic to aquatic life with long lasting effects. R10 Flammable. R23 Toxic by inhalation. R34 Causes burns. R50 Very toxic to aquatic organisms.
Training information: Users of breathing apparatus must be trained. Ensure operators understand the
toxicity hazard.
Classification according to Regulation (EC) No 1272/2008 as amended.
Other information: Before using this product in any new process or experiment, a thorough material compatibility and safety study should be carried out. Ensure adequate air ventilation. Ensure all national/local regulations are observed. Whilst proper care has been taken in the preparation of this document, no liability for injury or damage resulting from its use can be accepted. Note: When the Product Name appears in the SDS header the decimal sign and its position comply with rules for the structure and drafting of international standards, and is a comma on the line. As an example 2,000 is two (to three decimal places) and not two thousand, whilst 1.000 is one thousand and not one (to three decimal places).
Last revised date: 18.12.2015 Disclaimer: This information is provided without warranty. The information is believed to be
correct. This information should be used to make an independent determination of the methods to safeguard workers and the environment.
0PERSONAL PROTECTION E
REACTIVITY 0
HEALTH 1FLAMMABILITY 0 1
1
Asbury Graphite Mills, Inc. PO Box 144, 405 Old Main St. Asbury, NJ 08802 908-537-2155 Cummings – Moore Graphite Co. 1646 N. Green Ave. Detroit, MI 48209 313-841-1615 Anthracite Industries PO Box 112, Sunbury, PA 17801 570-286-2176 Southwestern Graphite PO Box 876, 2564 Hwy 12 DeQuincy, LA 70633 337-786-5905 Asbury Graphite of California 2855 Franklin Canyon Rd. Rodeo, CA 94572 510-799-3636
Material Safety Data Sheet (According regulation 1907/2006/EC and directives 67/548/EC and 1999/45/EC)
HMIS NFPA Flammability Health Reactivity Special Notice Section 1 – Identification of the Substance / Preparation, and of the Company Product Name/ Trade Name Natural Graphite: 85-98 Carbon Product Description Natural Graphite: 85-98 Carbon
Emergency Phone 1-800-255-3924 Information Phone 1-908-537-2155 Fax 1-908-537-2908 Date Prepared February 15, 2010
Manufacturer Asbury Carbons PO Box 144, 405 Old Main Street Asbury, NJ 08802
Preparer (optional) AVT Section 2 – Hazards Information Not Classified according EU regulations Powder/air mixtures can cause dust explosion (see chapter 9) Free Crystalline silica: Human Hazards: Free Cystalline Silica May Be Present. Silica Is An Inhalation Hazard When Present As Respirable Particulates. IARC Monograph Vol 68,1997 Conclude That There Is A Sufficient Evidence That Inhaled Crystalline Silica Causes Cancer In Humans. IARC Classification: Group 1
Section 3 – Composition / Information On Ingredients Hazardous Ingredients And Non Hazardous Ingredients Components CAS Number % Natural flake graphite 7782-42-5 100% Free crystalline silica (quartz) 14808-60-7 0.0-4.0% Section 4 – First Aid Measures Ingestion Natural graphite is not known to be toxic by ingestion. However, ingestion may cause digestive
system blockage. Skin Contact Wash with mild soap and warm water Eye Contact Rinse with tepid water until eyes are clear of particulates. Seek medical attention if irritation
persists. Inhalation Remove patient to particulate-free environment. Wear approved dust mask to avoid breathing
dust. Seek medical attention if irritation persists.
Section 5 – Fire Fighting Measures Natural graphite is not flammable under normal conditions Extinguishing Media Dry chemical extinguisher, water Protective Equipment Self contained air pack, gloves, safety goggles Special Hazards None Known NFP Rating 010 Section 6 – Accidental Release Measures Personal Precautions Dust mask, safety goggles, conventional gloves Methods for Cleaning Up: Conventional Sweep or vacuum. Avoid dusting conditions Section 7 – Handling and Storage Handling Conventional means to avoid dusting conditions. Natural graphite is a conductor of
electricity. Avoid contact between Natural graphite and electrical circuitry. Storage Store all carbonaceous materials in a dry location, away from oxidizing agents. Section 8 – Exposure Controls/ Personal Protection Control Parameters German or US Limits
Engineering Measures Use adequate dust collections to maintain dust levels below the control or recommended values.
Respiratory Protection Approved dust mask Eye Protection Conventional safety glasses or goggles. Skin Protection Conventional work gloves and clothing. Additional None Section 9 – Physical and Chemical Properties Colour: Gray to Black Material State Solid free flowing flakes or powder Odour None Boiling Point: 4827 C Melting Point Sublimates at 3652C Specific Gravity 2.26 Vapour Density Not applicable Vapor Pressure (mm Hg) NA % Volatile (By Wt.) 0-1% Solubility in Water Insoluble Evaporation Rate: Not applicable pH 6-8 Auto Ignition Above 500C Decomposition Temp Above 400C Dust Explosion class ST1=KST>0-200 bar.m/s Flash Point Not Applicable. When exposed to extremely high energy ignition sources fine
graphite and carbon powder can form explosive mixtures with air. Avoid contact between graphite or carbon dust clouds and high energy ignition sources.
Section 10 – Stability and Reactivity Stability Stable will not polymerize Conditions to Avoid Avoid contact with oxidizing agents Materials to Avoid Oxidizing agents Hazardous Decomposition Products
Carbon Dioxide (CO2) and carbon Monoxide (CO)
Section 11 – Toxicological Information
Toxicological information about natural graphite is not available. However, graphite is inert, insoluble and is not expected to present an ingestion hazard.
Section 12 – Ecological Information Assessment Natural graphite is inert and insoluble. To the best of our knowledge, Natural graphite
should not present any environmental hazards any more serious than any inert, insoluble dust or granular substance.
Section 13 – Disposal Considerations
Dispose of in a manner which conforms to local, state and Federal regulations.
Section 14 – Transport Information ICAO / IATA Shipping Name Natural Graphite Hazard Class Non Hazardous Subsidiary Class UN Number Packing Group None Transport Label Required No label required Additional Transport Info Technical Name (N.O.S.): Natural Graphite Section 15 – Regulatory Information EEC Marking and Labeling Symbol Not Known Risk Phases Graphite: R20 (harmful by inhalation), Silica: R49 (may cause cancer by inhalation) Safety Phases S14 (keep away from oxidizers), S22(do not breathe dust), S23 (avoid contact with
eyes), S39 (wear eye protection)
Warning : This product contains a chemical known to the state of California to cause cancer: Silica
Inventory Information: EEC EINECS: #231-995-3, Silica 238-878-4 US TSCA Yes Canada DSL Yes Section 16 – Other Information HMIS Rating 100E NFP Rating 110 Reason for Issue
Fluka - 38040 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Bromine concentrate
Product Number : 38040 Brand : Fluka REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Carcinogenicity (Category 1B), H350
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H315 Causes skin irritation. H319 Causes serious eye irritation. H350 May cause cancer. Precautionary statement(s) P201 Obtain special instructions before use.
Fluka - 38040 Page 2 of 7
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313 IF exposed or concerned: Get medical advice/ attention. Supplemental Hazard Statements
none
Restricted to professional users.
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
Fluka - 38040 Page 3 of 7
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Hydrogen bromide gas, Potassium oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Avoid exposure - obtain special instructions before use. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
hygroscopic Light sensitive. Store under inert gas. Storage class (TRGS 510): Combustible solids, toxic
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Fluka - 38040 Page 4 of 7
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (EN 143) respirator cartridges as a backup to engineering controls. If th full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: powder Colour: white
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
No data available
f) Initial boiling point and boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties The substance or mixture is not classified as oxidizing.
Fluka - 38040 Page 5 of 7
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Hydrogen bromide gas, Potassium oxides In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity No data available
Skin corrosion/irritation No data available
Serious eye damage/eye irritation No data available
Respiratory or skin sensitisation No data available
Germ cell mutagenicity No data available
Carcinogenicity
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Potassium bromate)
Reproductive toxicity No data available
Specific target organ toxicity - single exposure No data available
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available
Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Fluka - 38040 Page 6 of 7
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H271 May cause fire or explosion; strong oxidizer. H301 Toxic if swallowed.
Fluka - 38040 Page 7 of 7
H315 Causes skin irritation. H319 Causes serious eye irritation. H350 May cause cancer.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
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Material Safety Data SheetCalcium acetate MSDS
Section 1: Chemical Product and Company Identification
Product Name: Calcium acetate
Catalog Codes: SLC1777, SLC3568
CAS#: 62-54-4
RTECS: AF7525000
TSCA: TSCA 8(b) inventory: Calcium acetate
CI#: Not available.
Synonym:
Chemical Name: Calcium Acetate
Chemical Formula: C4H6CaO4
Contact Information:
Sciencelab.com, Inc.14025 Smith Rd.Houston, Texas 77396
US Sales: 1-800-901-7247International Sales: 1-281-441-4400
For non-emergency assistance, call: 1-281-441-4400
Section 2: Composition and Information on Ingredients
Composition:
Name CAS # % by Weight
Calcium acetate 62-54-4 100
Toxicological Data on Ingredients: Not applicable.
Section 3: Hazards Identification
Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, ofinhalation.
Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure is not known to aggravate medical condition.
Section 4: First Aid Measures
Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. Get medical attention if irritation occurs.
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold watermay be used.
Serious Skin Contact: Not available.
Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention.
Serious Inhalation: Not available.
Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar,tie, belt or waistband.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Flash Points: CLOSED CUP: Higher than 93.3°C (200°F).
Flammable Limits: Not available.
Products of Combustion:Products of combustion are carbon oxides (CO, CO2). Some metallic oxides. Products of Decompostion: acetone and calciumcarbonate
Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of heat.
Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available.
Fire Fighting Media and Instructions:SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
Section 6: Accidental Release Measures
Small Spill:Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water onthe contaminated surface and dispose of according to local and regional authority requirements.
Large Spill:Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on thecontaminated surface and allow to evacuate through the sanitary system.
Section 7: Handling and Storage
Precautions:Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under afume hood. Ground all equipment containing material. Do not breathe dust. Keep away from incompatibles such as oxidizingagents, moisture.
p. 3
Storage:Very Hygroscopic. Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 23°C(73.4°F).
Section 8: Exposure Controls/Personal Protection
Engineering Controls:Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommendedexposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminantsbelow the exposure limit.
Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.Gloves.
Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.
Exposure Limits: Not available.
Section 9: Physical and Chemical Properties
Physical state and appearance: Solid. (Crystals solid.)
Odor: Acetic acid. (Slight.)
Taste: Not available.
Molecular Weight: 158.17 g/mole
Color: White.
pH (1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: Not available.
Critical Temperature: Not available.
Specific Gravity: 1.5 (Water = 1)
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water.
Solubility: Soluble in cold water.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
p. 4
Instability Temperature: Not available.
Conditions of Instability: Excess heat, moisture, incompatible materials.
Incompatibility with various substances: Reactive with oxidizing agents, moisture.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity: Very hygroscopic.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Inhalation. Ingestion.
Toxicity to Animals:LD50: Not available. LC50: Not available.
Chronic Effects on Humans: Not available.
Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: May affect genetic material.
Special Remarks on other Toxic Effects on Humans:Acute Potential Heath Effects: Skin: May cause skin irritation. Eyes: Dust may cause eye irritation. Inhalation: Dust may causerespiratory tract irritation. Ingestion: May cause gastrointestinal (digestive) tract irritation. May affect brain. The toxicologicalproperities have not been fully investigated.
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Calcium acetate is biogradeable
Section 13: Disposal Considerations
Waste Disposal:Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not applicable.
p. 5
Section 15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory: Calcium acetate
Other Regulations: EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
Other Classifications:
WHMIS (Canada): Not controlled under WHMIS (Canada).
DSCL (EEC):This product is not classified according to the EU regulations. S24/25- Avoid contact with skin and eyes.
HMIS (U.S.A.):
Health Hazard: 1
Fire Hazard: 1
Reactivity: 0
Personal Protection: E
National Fire Protection Association (U.S.A.):
Health: 1
Flammability: 0
Reactivity: 0
Specific hazard:
Protective Equipment:Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses.
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/09/2005 04:30 PM
Last Updated: 05/21/2013 12:00 PM
The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assumeno liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.
Material Safety Data Sheet
Celite®
Section 1 - Chemical Product and Company Identification
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Chloroform
Product Number : 288306 Brand : Sigma-Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 67-66-3
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 4), H302 Acute toxicity, Inhalation (Category 3), H331 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Carcinogenicity (Category 2), H351 Reproductive toxicity (Category 2), H361d Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336 Specific target organ toxicity - repeated exposure (Category 1), H372
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger
Sigma-Aldrich - 288306 Page 2 of 7
Hazard statement(s) H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H331 Toxic if inhaled. H336 May cause drowsiness or dizziness. H351 Suspected of causing cancer. H361d Suspected of damaging the unborn child. H372 Causes damage to organs through prolonged or repeated exposure. Precautionary statement(s) P201 Obtain special instructions before use. P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.2 Mixtures Synonyms : Trichloromethane
Methylidyne trichloride
Formula : CHCl<SB>3</> Molecular weight : 119.38 g/mol Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Sigma-Aldrich - 288306 Page 3 of 7
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Hydrogen chloride gas
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Non Combustible Liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Sigma-Aldrich - 288306 Page 4 of 7
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Fluorinated rubber Minimum layer thickness: 0.7 mm Break through time: 480 min Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M) Splash contact Material: Fluorinated rubber Minimum layer thickness: 0.7 mm Break through time: 480 min Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engine protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid, clear Colour: colourless
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Melting point/range: -63 °C - lit.
f) Initial boiling point and boiling range
60.5 - 61.5 °C - lit.
g) Flash point No data available
Sigma-Aldrich - 288306 Page 5 of 7
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure 160.0 mmHg at 20.0 °C
l) Vapour density No data available
m) Relative density 1.492 g/mL at 25 °C1.48 g/mL at 25 °C
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
log Pow: 1.97
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Surface tension 27.1 mN/m at 20.0 °C
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions. Contains the following stabiliser(s): (>=0.5 - <=1 %)
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen chloride gas Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity No data available
Skin corrosion/irritation No data available
Sigma-Aldrich - 288306 Page 6 of 7
Serious eye damage/eye irritation No data available
Respiratory or skin sensitisation No data available
Germ cell mutagenicity No data available
Carcinogenicity
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Chloroform)
Reproductive toxicity No data available
Specific target organ toxicity - single exposure No data available
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available
Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Harmful to aquatic life.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1888 IMDG: 1888 IATA: 1888
Sigma-Aldrich - 288306 Page 7 of 7
14.2 UN proper shipping name ADR/RID: CHLOROFORM IMDG: CHLOROFORM IATA: Chloroform
14.3 Transport hazard class(es) ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H331 Toxic if inhaled. H336 May cause drowsiness or dizziness. H351 Suspected of causing cancer. H361d Suspected of damaging the unborn child. H372 Causes damage to organs through prolonged or repeated exposure.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 675644 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.1 Revision Date 15.07.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Chromium(VI) oxide
Product Number : 675644 Brand : Aldrich Index-No. : 024-001-00-0 REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 1333-82-0
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
For the full text of the H-Statements mentioned in this Section, see Section 16.
Aldrich - 675644 Page 2 of 8
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H271 May cause fire or explosion; strong oxidizer. H301 + H311 Toxic if swallowed or in contact with skin H314 Causes severe skin burns and eye damage. H317 May cause an allergic skin reaction. H330 Fatal if inhaled. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H340 May cause genetic defects. H350 May cause cancer. H361f Suspected of damaging fertility. H372 Causes damage to organs through prolonged or repeated exposure. H410 Very toxic to aquatic life with long lasting effects. Precautionary statement(s) P201 Obtain special instructions before use. P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection. P284 Wear respiratory protection. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse
mouth. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P371 + P380 + P375 In case of major fire and large quantities: Evacuate area. Fight fire
remotely due to the risk of explosion. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. Supplemental Hazard Statements
none
Restricted to professional users.
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Synonyms : Chromic anhydride
Formula : CrO<SB>3</> Molecular weight : 99.99 g/mol CAS-No. : 1333-82-0 EC-No. : 215-607-8 Index-No. : 024-001-00-0 Hazardous ingredients according to Regulation (EC) No 1272/2008
Aldrich - 675644 Page 3 of 8
Component Classification Concentration
Chromium (VI) oxide Included in the Candidate List of Substances of Very High Concern (SVHC) according to Regulation (EC) No. 1907/2006 (REACH)
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Chromium oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
Aldrich - 675644 Page 4 of 8
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Sweep up and shovel.\'20 Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Avoid exposure - obtain special instructions before use. Provide appropriate exhaust ventilation at places where dust is formed.Keep away from sources of ignition - No smoking. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min
Aldrich - 675644 Page 5 of 8
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (EN 143) respirator cartridges as a backup to engineering controls. If th full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: powder Colour: violet
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Melting point/range: 196 °C - dec.
f) Initial boiling point and boiling range
No data available
g) Flash point Not applicable
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density 2.700 g/cm3
n) Water solubility 1.667 g/l - soluble
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
Aldrich - 675644 Page 6 of 8
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties The substance or mixture is classified as oxidizing with the category 1.
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Chromium oxides Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - male and female - 52 mg/kg(Chromium (VI) oxide) (OECD Test Guideline 401) LC50 Inhalation - Rat - male - 4 h - 217 mg/m3(Chromium (VI) oxide) LD50 Dermal - Rabbit - male and female - 57 mg/kg(Chromium (VI) oxide) (OECD Test Guideline 402)
Respiratory or skin sensitisation No data available(Chromium (VI) oxide)
Germ cell mutagenicity May alter genetic material.(Chromium (VI) oxide) In vivo tests showed mutagenic effects(Chromium (VI) oxide)
Carcinogenicity This is or contains a component that has been reported to be carcinogenic classification.(Chromium (VI) oxide) Human carcinogen.(Chromium (VI) oxide)
IARC: 1 - Group 1: Carcinogenic to humans (Chromium (VI) oxide)
Aldrich - 675644 Page 7 of 8
Reproductive toxicity Suspected human reproductive toxicant(Chromium (VI) oxide)
May cause reproductive disorders.(Chromium (VI) oxide)
Specific target organ toxicity - single exposure No data available(Chromium (VI) oxide)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Chromium (VI) oxide)
Additional Information RTECS: GB6650000 Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea(Chromium (VI) oxide)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Tilapia mossambica - 21.05 - 141.38 mg/l - 96.0 h(Chromium (VI)
oxide) LC0 - Leuciscus idus (Golden orfe) - 100 mg/l - 48.0 h(Chromium (VI) oxide) Toxicity to daphnia and other aquatic invertebrates
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Chromium (VI) oxide)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Very toxic to aquatic life with long lasting effects.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1463 IMDG: 1463 IATA: 1463
Aldrich - 675644 Page 8 of 8
14.2 UN proper shipping name ADR/RID: CHROMIUM TRIOXIDE, ANHYDROUS IMDG: CHROMIUM TRIOXIDE, ANHYDROUS IATA: Chromium trioxide, anhydrous
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Authorisations and/or restrictions on use 15.2 Chemical safety assessment
For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H271 May cause fire or explosion; strong oxidizer. H301 Toxic if swallowed. H301 + H311 Toxic if swallowed or in contact with skin H311 Toxic in contact with skin. H314 Causes severe skin burns and eye damage. H317 May cause an allergic skin reaction. H330 Fatal if inhaled. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H340 May cause genetic defects. H350 May cause cancer. H361f Suspected of damaging fertility. H372 Causes damage to organs through prolonged or repeated exposure. H400 Very toxic to aquatic life. H410 Very toxic to aquatic life with long lasting effects.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 251275 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Citric acid
Product Number : 251275 Brand : Sigma-Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 77-92-9
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Eye irritation (Category 2), H319
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Warning Hazard statement(s) H319 Causes serious eye irritation. Precautionary statement(s) P280 Wear eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P337 + P313 If eye irritation persists: Get medical advice/ attention.
Sigma-Aldrich - 251275 Page 2 of 7
Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Formula : C6H8O7
Molecular weight : 192.12 g/mol CAS-No. : 77-92-9 EC-No. : 201-069-1 Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Citric acid
CAS-No. EC-No.
77-92-9 201-069-1
Eye Irrit. 2; H319 <= 100 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
Sigma-Aldrich - 251275 Page 3 of 7
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min
Sigma-Aldrich - 251275 Page 4 of 7
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle r (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: crystalline Colour: white
b) Odour No data available
c) Odour Threshold No data available
d) pH 1.8 at ca.50 g/l at 25 °C
e) Melting point/freezing point
Melting point/range: 153 - 159 °C - lit.
f) Initial boiling point and boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
Lower explosion limit: 8 %(V)
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility 383 g/l at 25 °C
o) Partition coefficient: n-octanol/water
log Pow: -1.639 at 20 °C
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
Sigma-Aldrich - 251275 Page 5 of 7
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Carbon oxides In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 5,400 mg/kg(Citric acid) (OECD Test Guideline 401) LD50 Dermal - Rat - > 2,000 mg/kg(Citric acid) (OECD Test Guideline 402)
Serious eye damage/eye irritation Eyes - Rabbit(Citric acid) Result: Irritating to eyes. (OECD Test Guideline 405)
Respiratory or skin sensitisation Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals.(Citric acid)
Germ cell mutagenicity No data available(Citric acid)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available(Citric acid)
Specific target organ toxicity - single exposure No data available(Citric acid)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Citric acid)
Sigma-Aldrich - 251275 Page 6 of 7
Additional Information RTECS: GE7350000 Vomiting, Diarrhoea, Damage to tooth enamel., Dermatitis, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Citric acid)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish mortality LC50 - Leuciscus idus melanotus - 440 mg/l - 48 h(Citric acid)
(OECD Test Guideline 203) Toxicity to daphnia and other aquatic invertebrates
static test - Daphnia magna (Water flea) - 1,535 mg/l - 24 h(Citric acid)
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Citric acid)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
Sigma-Aldrich - 251275 Page 7 of 7
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H319 Causes serious eye irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 792063 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Copper(I) iodide
Product Number : 792063 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 7681-65-4
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 4), H302 Skin irritation (Category 2), H315 Serious eye damage (Category 1), H318 Skin sensitisation (Category 1), H317 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Acute aquatic toxicity (Category 1), H400 Chronic aquatic toxicity (Category 1), H410
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H302 Harmful if swallowed.
Aldrich - 792063 Page 2 of 7
H315 Causes skin irritation. H317 May cause an allergic skin reaction. H318 Causes serious eye damage. H335 May cause respiratory irritation. H410 Very toxic to aquatic life with long lasting effects. Precautionary statement(s) P280 Wear protective gloves/ eye protection/ face protection. P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
Rinse mouth. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Synonyms : Cuprous Iodide
Formula : CuI Molecular weight : 190.45 g/mol CAS-No. : 7681-65-4 EC-No. : 231-674-6 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Aldrich - 792063 Page 3 of 7
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Hydrogen iodide, Copper oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Light sensitive. Handle and store under inert gas. Hygroscopic. Storage class (TRGS 510): Non Combustible Solids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Aldrich - 792063 Page 4 of 7
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (EN 143) respirator cartridges as a backup to engineering controls. If th full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: powder Colour: brown
b) Odour odourless
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
605 °C
f) Initial boiling point and boiling range
1,290 °C
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure 10 mmHg at 656 °C
l) Vapour density No data available
m) Relative density 5.620 g/cm3 at 20 °C
n) Water solubility insoluble
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
Aldrich - 792063 Page 5 of 7
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Bulk density 1,400 kg/m3
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Hydrogen iodide, Copper oxides In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - female - 300 - 2,000 mg/kg(Copper iodide) (OECD Test Guideline 420) LD50 Dermal - Rat - male and female - > 2,000 mg/kg(Copper iodide) (OECD Test Guideline 402)
Skin corrosion/irritation No data available(Copper iodide)
Serious eye damage/eye irritation Eyes - Rabbit(Copper iodide) Result: Risk of serious damage to eyes. (OECD Test Guideline 405)
Respiratory or skin sensitisation Maximisation Test - Guinea pig(Copper iodide) Result: May cause sensitisation by skin contact. (OECD Test Guideline 406)
Germ cell mutagenicity No data available(Copper iodide)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(Copper iodide)
Aldrich - 792063 Page 6 of 7
Specific target organ toxicity - single exposure No data available(Copper iodide)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Copper iodide)
Additional Information RTECS: Not available Symptoms of systemic copper poisoning may include: capillary damage, heada central nervous system excitation followed by depression, jaundice, convu renal failure. Chronic copper poisoning is typified by hepatic cirrhosis, copper deposition in the cornea as exemplified by humans with Wilson's di lead to hemolytic anemia and accelerates arteriosclerosis., To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Copper iodide) Liver - Irregularities - Based on Human Evidence(Copper iodide)
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Copper iodide)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Very toxic to aquatic life with long lasting effects.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 3077 IMDG: 3077 IATA: 3077
Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H302 Harmful if swallowed. H315 Causes skin irritation. H317 May cause an allergic skin reaction. H318 Causes serious eye damage. H335 May cause respiratory irritation. H400 Very toxic to aquatic life. H410 Very toxic to aquatic life with long lasting effects.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 227048 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Cyclohexane
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Skin irritation (Category 2), H315 Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336 Aspiration hazard (Category 1), H304 Acute aquatic toxicity (Category 1), H400 Chronic aquatic toxicity (Category 1), H410
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H304 May be fatal if swallowed and enters airways. H315 Causes skin irritation. H336 May cause drowsiness or dizziness.
Sigma-Aldrich - 227048 Page 2 of 8
H410 Very toxic to aquatic life with long lasting effects. Precautionary statement(s) P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. P261 Avoid breathing vapours. P273 Avoid release to the environment. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor. P331 Do NOT induce vomiting. P501 Dispose of contents/ container to an approved waste disposal plant. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Flush eyes with water as a precaution.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
Sigma-Aldrich - 227048 Page 3 of 8
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Store under inert gas. Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Sigma-Aldrich - 227048 Page 4 of 8
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 480 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 35 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5
Sigma-Aldrich - 227048 Page 6 of 8
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 12,705 mg/kg(Cyclohexane) LC50 Inhalation - Rat - 4 h - 34,000 mg/l(Cyclohexane) (OECD Test Guideline 403) LD50 Dermal - Rabbit - > 2,000 mg/kg(Cyclohexane)
Skin corrosion/irritation Skin - Rabbit(Cyclohexane) Result: No skin irritation Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)(Cyclohexane)
Respiratory or skin sensitisation No data available(Cyclohexane)
Germ cell mutagenicity No data available(Cyclohexane)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(Cyclohexane)
Specific target organ toxicity - single exposure No data available(Cyclohexane)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard May be fatal if swallowed and enters airways.(Cyclohexane)
Additional Information RTECS: GU6300000 Central nervous system depression, Drowsiness, Irritability, Dizziness, Gastrointestinal disturbance, Lung irritation, chest pain, pulmonary edema(Cyclohexane)
SECTION 12: Ecological information
12.1 Toxicity Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2) Toxicity to daphnia and other aquatic invertebrates
Immobilization EC50 - Daphnia magna (Water flea) - 0.9 mg/l - 48 h(Cyclohexane) (OECD Test Guideline 202)
12.2 Persistence and degradability Biodegradability Result: - Readily biodegradable
Sigma-Aldrich - 227048 Page 7 of 8
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Cyclohexane)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Very toxic to aquatic life.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1145 IMDG: 1145 IATA: 1145
14.2 UN proper shipping name ADR/RID: CYCLOHEXANE IMDG: CYCLOHEXANE IATA: Cyclohexane
14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H225 Highly flammable liquid and vapour. H304 May be fatal if swallowed and enters airways. H315 Causes skin irritation. H336 May cause drowsiness or dizziness. H400 Very toxic to aquatic life. H410 Very toxic to aquatic life with long lasting effects.
Sigma-Aldrich - 227048 Page 8 of 8
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 142549 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : 3-Chloropropylamine hydrochloride
Product Number : 142549 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 6276-54-6
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Warning Hazard statement(s) H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.
Aldrich - 142549 Page 2 of 7
Precautionary statement(s) P261 Avoid breathing dust. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Aldrich - 142549 Page 3 of 7
5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm
Aldrich - 142549 Page 4 of 7
Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle r (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: powder Colour: light brown
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Melting point/range: 145 - 150 °C - lit.
f) Initial boiling point and boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
Aldrich - 142549 Page 5 of 7
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity No data available3-Chloropropylamine hydrochloride
Skin corrosion/irritation No data available(3-Chloropropylamine hydrochloride)
Serious eye damage/eye irritation No data available(3-Chloropropylamine hydrochloride)
Respiratory or skin sensitisation No data available(3-Chloropropylamine hydrochloride)
Germ cell mutagenicity No data available(3-Chloropropylamine hydrochloride)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(3-Chloropropylamine hydrochloride)
Specific target organ toxicity - single exposure Inhalation - May cause respiratory irritation.(3-Chloropropylamine hydrochloride)
Specific target organ toxicity - repeated exposure No data available
Aldrich - 142549 Page 6 of 7
Aspiration hazard No data available(3-Chloropropylamine hydrochloride)
Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(3-Chloropropylamine hydrochloride)
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(3-Chloropropylamine hydrochloride)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
Aldrich - 142549 Page 7 of 7
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 517135 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Diethyl carbonate
Product Number : 517135 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 105-58-8
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 3), H226 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Specific target organ toxicity - single exposure (Category 3), H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Warning Hazard statement(s) H226 Flammable liquid and vapour. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.
Aldrich - 517135 Page 2 of 7
Precautionary statement(s) P261 Avoid breathing vapours. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Formula : C<SB>5</>H<SB>10</>O<SB>3</>C<SB>5</>H<SB>10</>O<SB>3</> Molecular weight : 118.13 g/mol CAS-No. : 105-58-8 EC-No. : 203-311-1 Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Diethyl carbonate
CAS-No. EC-No.
105-58-8 203-311-1
Flam. Liq. 3; H226 <= 100 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Aldrich - 517135 Page 3 of 7
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Store under inert gas. Moisture sensitive. Storage class (TRGS 510): Flammable Liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
Aldrich - 517135 Page 4 of 7
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Splash contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 120 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: clear, liquid Colour: colourless
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Melting point/range: -43 °C - lit.
f) Initial boiling point and boiling range
126 - 128 °C - lit.
g) Flash point 25 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure 59 mmHg at 37.8 °C 10 mmHg at 23.8 °C
l) Vapour density 4.08 - (Air = 1.0)
m) Relative density 0.975 g/cm3 at 25 °C
n) Water solubility insoluble
o) Partition coefficient: n-octanol/water
No data available
Aldrich - 517135 Page 5 of 7
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative vapour density 4.08 - (Air = 1.0)
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - male - > 4,876 mg/kg(Diethyl carbonate) LC50 Inhalation - Rat - female - 7 h - > 1.268 mg/l(Diethyl carbonate) LD50 Subcutaneous - Rat - 8,500 mg/kg(Diethyl carbonate)
Skin corrosion/irritation Skin - Rabbit(Diethyl carbonate) Result: No skin irritation
Respiratory or skin sensitisation - Mouse(Diethyl carbonate) Result: Does not cause skin sensitisation. (OECD Test Guideline 429)
Germ cell mutagenicity No data available(Diethyl carbonate) Salmonella typhimurium Result: negative
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
Aldrich - 517135 Page 6 of 7
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Specific target organ toxicity - single exposure No data available(Diethyl carbonate)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Diethyl carbonate)
Additional Information
Repeated dose toxicity - Mouse - male - Oral - Lowest observed adverse effect level - 50 mg/kg(Diethyl carbonate) RTECS: FF9800000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Diethyl carbonate)
SECTION 12: Ecological information
12.1 Toxicity No data available Toxicity to daphnia and other aquatic invertebrates
Immobilization NOEC - Daphnia magna Straus - >= 100 mg/l - 48 h(Diethyl carbonate) (OECD Test Guideline 202)
12.4 Mobility in soil No data available(Diethyl carbonate)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
Aldrich - 517135 Page 7 of 7
SECTION 14: Transport information
14.1 UN number ADR/RID: 2366 IMDG: 2366 IATA: 2366
14.2 UN proper shipping name ADR/RID: DIETHYL CARBONATE IMDG: DIETHYL CARBONATE IATA: Diethyl carbonate
14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3
14.4 Packaging group ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H226 Flammable liquid and vapour. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 270997 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.1 Revision Date 15.07.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Dichloromethane
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Carcinogenicity (Category 2), H351 Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Specific target organ toxicity - repeated exposure, Oral (Category 2), Liver, Blood, H373 Specific target organ toxicity - repeated exposure, Inhalation (Category 2), Central nervous system, H373
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Warning Hazard statement(s) H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.
Sigma-Aldrich - 270997 Page 2 of 8
H336 May cause drowsiness or dizziness. H351 Suspected of causing cancer. H373 May cause damage to organs (Liver, Blood) through prolonged or
repeated exposure if swallowed. H373 May cause damage to organs (Central nervous system) through
prolonged or repeated exposure if inhaled. Precautionary statement(s) P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Sigma-Aldrich - 270997 Page 3 of 8
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Hydrogen chloride gas
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Heat sensitive. Handle and store under inert gas. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Splash contact Material: Fluorinated rubber Minimum layer thickness: 0.7 mm Break through time: 148 min Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engine protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Sigma-Aldrich - 270997 Page 5 of 8
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
10.6 Hazardous decomposition products Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen chloride gas In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - > 2,000 mg/kg(Methylene chloride) LC50 Inhalation - Rat - 52,000 mg/m3(Methylene chloride) LD50 Dermal - Rat - > 2,000 mg/kg(Methylene chloride) (OECD Test Guideline 402)
Skin corrosion/irritation Skin - Rabbit(Methylene chloride) Result: Irritating to skin. - 24 h (Draize Test)
Serious eye damage/eye irritation Eyes - Rabbit(Methylene chloride) Result: Irritating to eyes. - 24 h (Draize Test)
Respiratory or skin sensitisation No data available(Methylene chloride)
Germ cell mutagenicity (Methylene chloride) Rat DNA damage
Carcinogenicity Limited evidence of carcinogenicity in animal studies(Methylene chloride) Suspected human carcinogens(Methylene chloride)
IARC: 2A - Group 2A: Probably carcinogenic to humans (Methylene chloride)
Reproductive toxicity
No data available(Methylene chloride)
Specific target organ toxicity - single exposure May cause respiratory irritation.(Methylene chloride) May cause drowsiness or dizziness.(Methylene chloride)
Specific target organ toxicity - repeated exposure Inhalation - May cause damage to organs through prolonged or repeated exposure. - Central nervous system Oral - May cause damage to organs through prolonged or repeated exposure. - Liver, Blood
Aspiration hazard No data available(Methylene chloride)
Additional Information RTECS: PA8050000
Sigma-Aldrich - 270997 Page 7 of 8
Dichloromethane is metabolized in the body producing carbon monoxide which blood, reducing the oxygen-carrying capacity of the blood., Acts as a simple asphyxiant by displacing air., anesthetic effects, Difficulty in breathing, Headache, Dizziness, Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred vision, Provokes tears., Effects due to ingestion may include:, Gastrointestinal discomfort, Central nervous system depression, Paresthesia., Drowsiness, Convulsions, Conjunctivitis., Pulmonary edema. Effects may be delayed., Irregular breathing., Stomach/intestinal disorders, Nausea, Vomiting, Increased liver enzymes., Weakness, Heavy or prolonged skin exposure may result in the absorption of harmful amounts of material., Abdominal pain(Methylene chloride) To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Methylene chloride)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 193.00 mg/l - 96 h(Methylene
12.2 Persistence and degradability Biodegradability Result: < 26 % - Not readily biodegradable.
(OECD Test Guideline 301C)
12.3 Bioaccumulative potential Does not bioaccumulate.
12.4 Mobility in soil No data available(Methylene chloride)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1593 IMDG: 1593 IATA: 1593
14.2 UN proper shipping name ADR/RID: DICHLOROMETHANE IMDG: DICHLOROMETHANE IATA: Dichloromethane
14.3 Transport hazard class(es) ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
Sigma-Aldrich - 270997 Page 8 of 8
14.4 Packaging group ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment A Chemical Safety Assessment has been carried out for this substance.
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H336 May cause drowsiness or dizziness. H351 Suspected of causing cancer. H373 May cause damage to organs through prolonged or repeated exposure if inhaled.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 270997 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com Material Safety Data Sheet
Version 5.0 Revision Date 04/21/2012
Print Date 05/21/2012
1. PRODUCT AND COMPANY IDENTIFICATION
Product name : Dichloromethane
Product Number : 270997 Brand : Sigma-Aldrich Supplier : Sigma-Aldrich
3050 Spruce Street SAINT LOUIS MO 63103 USA
Telephone : +1 800-325-5832 Fax : +1 800-325-5052 Emergency Phone # (For both supplier and manufacturer)
: (314) 776-6555
Preparation Information : Sigma-Aldrich Corporation Product Safety - Americas Region 1-800-521-8956
2. HAZARDS IDENTIFICATION
Emergency Overview
OSHA Hazards Carcinogen, Target Organ Effect, Harmful by ingestion., Irritant
Target Organs
Liver, pancreas, Blood, Central nervous system, Heart, Kidney
GHS Label elements, including precautionary statements
Pictogram
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed. H315 + H320 Causes skin and eye irritation. H351 Suspected of causing cancer.
Precautionary statement(s) P281 Use personal protective equipment as required. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing.
HMIS Classification Health hazard: 2 Chronic Health Hazard: * Flammability: 0 Physical hazards: 0
Sigma-Aldrich - 270997 Page 2 of 7
NFPA Rating Health hazard: 2 Fire: 0 Reactivity Hazard: 0
Potential Health Effects
Inhalation May be harmful if inhaled. Causes respiratory tract irritation. Skin Harmful if absorbed through skin. Causes skin irritation. Eyes Causes eye irritation. Ingestion Harmful if swallowed.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Synonyms : Methylene chloride
Formula : CH2Cl2
Molecular Weight : 84.93 g/mol
Component Concentration
Methylene chloride
CAS-No. EC-No. Index-No.
75-09-2 200-838-9 602-004-00-3
-
4. FIRST AID MEASURES
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
5. FIREFIGHTING MEASURES
Conditions of flammability Not flammable or combustible.
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for firefighters Wear self contained breathing apparatus for fire fighting if necessary.
Hazardous combustion products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen chloride gas
6. ACCIDENTAL RELEASE MEASURES
Personal precautions Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.
Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Sigma-Aldrich - 270997 Page 3 of 7
Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.
7. HANDLING AND STORAGE
Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Conditions for safe storage Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Heat sensitive. Store under inert gas.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Components with workplace control parameters
Components CAS-No. Value Control parameters
Basis
Remarks Potential Occupational Carcinogen See Appendix A
Methylene chloride
75-09-2 TWA
50 ppm
USA. ACGIH Threshold Limit Values (TLV)
Central Nervous System impairment Carboxyhemoglobinemia Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Confirmed animal carcinogen with unknown relevance to humans
Substance listed; for more information see OSHA document 1910.1052
See 1910.1052
Personal protective equipment
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Hand protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
Eye protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin and body protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Form liquid
Colour colourless
Sigma-Aldrich - 270997 Page 4 of 7
Safety data
pH no data available
Melting point/freezing point
Melting point/range: -97 °C (-143 °F)
Boiling point 39.8 - 40 °C (103.6 - 104 °F)
Flash point no data available
Ignition temperature 556.1 °C (1,033.0 °F)
Autoignition temperature
556.1 °C (1,033.0 °F)
662.0 °C (1,223.6 °F)
Lower explosion limit 12 %(V)
Upper explosion limit 19 %(V)
Vapour pressure 470.9 hPa (353.2 mmHg) at 20.0 °C (68.0 °F)
Density 1.325 g/mL at 25 °C (77 °F)
Water solubility slightly soluble
Partition coefficient: n-octanol/water
log Pow: 1.25
Relative vapour density
2.93 - (Air = 1.0)
Odour no data available
Odour Threshold no data available
Evaporation rate 0.71
10. STABILITY AND REACTIVITY
Chemical stability Stable under recommended storage conditions.
Possibility of hazardous reactions no data available
Conditions to avoid Heat, flames and sparks. Exposure to sunlight.
Materials to avoid Alkali metals, Aluminum, Strong oxidizing agents, Bases, Amines, Magnesium, Strong acids and strong bases, Vinyl compounds
Hazardous decomposition products Other decomposition products - no data available Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen chloride gas Contains the following stabiliser(s): 2-Methyl-2-butene (>0.005 - <0.015 %)
Respiratory or skin sensitization no data available
Germ cell mutagenicity
Genotoxicity in vivo - rat - Oral DNA damage
Carcinogenicity
Carcinogenicity - rat - Inhalation Tumorigenic:Carcinogenic by RTECS criteria. Endocrine:Tumors.
Limited evidence of carcinogenicity in animal studies
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Methylene chloride)
NTP: Reasonably anticipated to be a human carcinogen (Methylene chloride)
Reproductive toxicity
no data available
Teratogenicity
Specific target organ toxicity - single exposure (Globally Harmonized System) no data available
Specific target organ toxicity - repeated exposure (Globally Harmonized System) no data available
Aspiration hazard no data available
Potential health effects
Inhalation May be harmful if inhaled. Causes respiratory tract irritation. Ingestion Harmful if swallowed. Skin Harmful if absorbed through skin. Causes skin irritation. Eyes Causes eye irritation.
Signs and Symptoms of Exposure Dichloromethane is metabolized in the body producing carbon monoxide which increases and sustains carboxyhemoglobin levels in the blood, reducing the oxygen-carrying capacity of the blood., Acts as a simple asphyxiant by displacing air., anesthetic effects, Difficulty in breathing, Headache, Dizziness, Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred vision, Provokes tears., Effects due to ingestion may include:, Gastrointestinal discomfort, Central nervous system depression, Paresthesia., Drowsiness, Convulsions, Conjunctivitis., Pulmonary edema. Effects may be delayed., Irregular breathing., Stomach/intestinal disorders, Nausea, Vomiting, Increased liver enzymes., Weakness, Heavy or prolonged skin exposure may result in the absorption of harmful amounts of material., Abdominal pain
Synergistic effects no data available
Additional Information RTECS: PA8050000
12. ECOLOGICAL INFORMATION
Toxicity
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 193.00 mg/l - 96 h
Toxicity to daphnia and other aquatic invertebrates
EC50 - Daphnia magna (Water flea) - 1,682.00 mg/l - 48 h
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects
no data available
13. DISPOSAL CONSIDERATIONS
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging Dispose of as unused product.
14. TRANSPORT INFORMATION
DOT (US) UN number: 1593 Class: 6.1 Packing group: III Proper shipping name: Dichloromethane Reportable Quantity (RQ): 1000 lbs Marine pollutant: No Poison Inhalation Hazard: No IMDG UN number: 1593 Class: 6.1 Packing group: III EMS-No: F-A, S-A Proper shipping name: DICHLOROMETHANE Marine pollutant: No IATA UN number: 1593 Class: 6.1 Packing group: III Proper shipping name: Dichloromethane
15. REGULATORY INFORMATION
OSHA Hazards Carcinogen, Target Organ Effect, Harmful by ingestion., Irritant
SARA 302 Components SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
Methylene chloride
CAS-No. 75-09-2
Revision Date 2007-07-01
Sigma-Aldrich - 270997 Page 7 of 7
Pennsylvania Right To Know Components Methylene chloride
CAS-No. 75-09-2
Revision Date 2007-07-01
New Jersey Right To Know Components Methylene chloride
CAS-No. 75-09-2
Revision Date 2007-07-01
California Prop. 65 Components WARNING! This product contains a chemical known to the State of California to cause cancer. Methylene chloride
CAS-No. 75-09-2
Revision Date 2007-09-28
16. OTHER INFORMATION
Further information Copyright 2012 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - D97754 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Diethyl malonate
Product Number : D97754 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 105-53-3
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Eye irritation (Category 2), H319
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Warning Hazard statement(s) H319 Causes serious eye irritation. Precautionary statement(s) P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
Aldrich - D97754 Page 2 of 7
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Molecular weight : 160.17 g/mol CAS-No. : 105-53-3 EC-No. : 203-305-9 Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Diethyl malonate
CAS-No. EC-No.
105-53-3 203-305-9
Eye Irrit. 2; H319 <= 100 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
Aldrich - D97754 Page 3 of 7
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Combustible liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M)
Aldrich - D97754 Page 4 of 7
Splash contact Material: Nature latex/chloroprene Minimum layer thickness: 0.6 mm Break through time: 30 min Material tested:Lapren® (KCL 706 / Aldrich Z677558, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid Colour: colourless
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Melting point/range: -51 - -50 °C - lit.
f) Initial boiling point and boiling range
199 °C - lit.
g) Flash point 90 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure 1 mmHg at 40 °C
l) Vapour density 5.53 - (Air = 1.0)
m) Relative density 1.055 g/cm3 at 25 °C
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
log Pow: 0.415
p) Auto-ignition temperature
No data available
q) Decomposition No data available
Aldrich - D97754 Page 5 of 7
temperature
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative vapour density 5.53 - (Air = 1.0)
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5
Serious eye damage/eye irritation No data available(Diethyl malonate)
Respiratory or skin sensitisation No data available(Diethyl malonate)
Germ cell mutagenicity No data available(Diethyl malonate)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(Diethyl malonate)
Specific target organ toxicity - single exposure No data available(Diethyl malonate)
Specific target organ toxicity - repeated exposure No data available
Aldrich - D97754 Page 6 of 7
Aspiration hazard No data available(Diethyl malonate)
Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Diethyl malonate)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 10.8 mg/l - 96 h(Diethyl
malonate)
12.2 Persistence and degradability Biodegradability aerobic - Exposure time 28 d(Diethyl malonate)
Result: 99 % - Readily biodegradable
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Diethyl malonate)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Harmful to aquatic life. No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product This combustible material may be burned in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
Aldrich - D97754 Page 7 of 7
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H319 Causes serious eye irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 386464 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Diisopropylamine
Product Number : 386464 Brand : Sigma-Aldrich Index-No. : 612-129-00-5 REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 108-18-9
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Acute toxicity, Oral (Category 4), H302 Acute toxicity, Inhalation (Category 3), H331 Skin corrosion (Category 1A), H314
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H302 Harmful if swallowed. H314 Causes severe skin burns and eye damage.
Sigma-Aldrich - 386464 Page 2 of 8
H331 Toxic if inhaled. Precautionary statement(s) P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. Lachrymator., Rapidly absorbed through skin.
SECTION 3: Composition/information on ingredients
3.1 Substances Synonyms : DIPA
Formula : C<SB>6</>H<SB>15</>N Molecular weight : 101.19 g/mol CAS-No. : 108-18-9 EC-No. : 203-558-5 Index-No. : 612-129-00-5 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Sigma-Aldrich - 386464 Page 3 of 8
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx) Flash back possible over considerable distance., Container explosion may occur under fire conditions.
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Sigma-Aldrich - 386464 Page 4 of 8
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 480 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 480 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid, clear Colour: colourless
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx) Other decomposition products - No data available In the event of fire: see section 5
Sigma-Aldrich - 386464 Page 6 of 8
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - male and female - 420 mg/kg(Diisopropylamine) LC50 Inhalation - Rat - male and female - 4 h - 5.35 mg/l(Diisopropylamine) (OECD Test Guideline 403) LD50 Dermal - Rabbit - > 10,000 mg/kg(Diisopropylamine)
Skin corrosion/irritation Skin - Rabbit(Diisopropylamine) Result: Causes severe burns. - 3 min (OECD Test Guideline 404)
Serious eye damage/eye irritation Eyes - Rabbit(Diisopropylamine) Result: Risk of serious damage to eyes. - 24 h (OECD Test Guideline 405)
Respiratory or skin sensitisation Maximisation Test - Guinea pig(Diisopropylamine) Result: Does not cause skin sensitisation. (OECD Test Guideline 406)
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available(Diisopropylamine)
Specific target organ toxicity - single exposure No data available(Diisopropylamine)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Diisopropylamine)
Additional Information
Repeated dose toxicity - Rat - male and female - Oral - No observed adverse effect level - 50 mg/kg(Diisopropylamine)
Repeated dose toxicity - Rat - male and female - No observed adverse effect level - >= 150 mg/kg(Diisopropylamine) RTECS: IM4025000 burning sensation, Cough, wheezing, laryngitis, Shortness of breath, spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Diisopropylamine) Liver - Irregularities - Based on Human Evidence(Diisopropylamine)
Sigma-Aldrich - 386464 Page 7 of 8
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish semi-static test LC50 - Gasterosteus aculeatus - 798 mg/l - 96
h(Diisopropylamine) Toxicity to daphnia and other aquatic invertebrates
static test LC50 - Daphnia magna (Water flea) - 110 mg/l - 48 h(Diisopropylamine)
Toxicity to algae static test EC50 - SELENASTRUM - 20 mg/l - 96 h(Diisopropylamine) Toxicity to bacteria Respiration inhibition EC50 - activated sludge - > 100 mg/l - 3
h(Diisopropylamine) (OECD Test Guideline 209)
12.2 Persistence and degradability Biodegradability aerobic - Exposure time 28 d(Diisopropylamine)
Result: 11 % - Not readily biodegradable. (OECD Test Guideline 301D)
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Diisopropylamine)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Harmful to aquatic life.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1158 IMDG: 1158 IATA: 1158
14.2 UN proper shipping name ADR/RID: DIISOPROPYLAMINE IMDG: DIISOPROPYLAMINE IATA: Diisopropylamine
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
Sigma-Aldrich - 386464 Page 8 of 8
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H225 Highly flammable liquid and vapour. H302 Harmful if swallowed. H314 Causes severe skin burns and eye damage. H331 Toxic if inhaled. H335 May cause respiratory irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 227056 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : N,N-Dimethylformamide
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H226 Flammable liquid and vapour. H312 + H332 Harmful in contact with skin or if inhaled H319 Causes serious eye irritation. H360D May damage the unborn child.
Sigma-Aldrich - 227056 Page 2 of 8
Precautionary statement(s) P201 Obtain special instructions before use. P210 Keep away from heat, hot surfaces, sparks, open flames and other
protection. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P370 + P378 In case of fire: Use dry powder or dry sand to extinguish. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. Rapidly absorbed through skin.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Sigma-Aldrich - 227056 Page 3 of 8
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx)
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid exposure - obtain special instructions before use.Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Handle and store under inert gas. Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Workers Inhalation Long-term local effects 15 mg/m3
Workers Inhalation Acute local effects 30 mg/m3
Predicted No Effect Concentration (PNEC)
Compartment Value
Water 30 mg/l
Soil 16.235 mg/kg
Marine water 3 mg/kg
Fresh water 30 mg/l
Fresh water sediment 25.05 mg/kg
Onsite sewage treatment plant 123 mg/l
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nature latex/chloroprene Minimum layer thickness: 0.6 mm Break through time: 65 min Material tested:Lapren® (KCL 706 / Aldrich Z677558, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Sigma-Aldrich - 227056 Page 5 of 8
Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid, clear Colour: colourless
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx) Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 2,800 mg/kg(N,N-Dimethylformamide) LC50 Inhalation - Rat - 4 h - 9 - 15 mg/l(N,N-Dimethylformamide) LD50 Dermal - Rabbit - 1,500 mg/kg(N,N-Dimethylformamide)
Respiratory or skin sensitisation No data available(N,N-Dimethylformamide)
Germ cell mutagenicity Mouse(N,N-Dimethylformamide) lymphocyte Mutation in mammalian somatic cells.
Carcinogenicity This product is or contains a component that is not classifiable as to its classification.(N,N-Dimethylformamide)
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (N,N-Dimethylformamide)
Reproductive toxicity May cause congenital malformation in the fetus.(N,N-Dimethylformamide)
Specific target organ toxicity - single exposure No data available(N,N-Dimethylformamide)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(N,N-Dimethylformamide)
Sigma-Aldrich - 227056 Page 7 of 8
Additional Information RTECS: LQ2100000 Warning: intolerance for alcohol can occur up to 4 days after dimethylform a potent liver toxin., Vomiting, Diarrhoea, Abdominal pain, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(N,N-Dimethylformamide)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Oncorhynchus mykiss (rainbow trout) - 9,000 - 13,000 mg/l - 96 h(N,N-
12.4 Mobility in soil No data available(N,N-Dimethylformamide)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
Sigma-Aldrich - 227056 Page 8 of 8
SECTION 14: Transport information
14.1 UN number ADR/RID: 2265 IMDG: 2265 IATA: 2265
14.2 UN proper shipping name ADR/RID: N,N-DIMETHYLFORMAMIDE IMDG: N,N-DIMETHYLFORMAMIDE IATA: N,N-Dimethylformamide
14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3
14.4 Packaging group ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Authorisations and/or restrictions on use 15.2 Chemical safety assessment
A Chemical Safety Assessment has been carried out for this substance.
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H226 Flammable liquid and vapour. H312 Harmful in contact with skin. H312 + H332 Harmful in contact with skin or if inhaled H319 Causes serious eye irritation. H332 Harmful if inhaled. H360 May damage fertility or the unborn child. H360D May damage the unborn child.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 126365 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Dimethylamine hydrochloride
Product Number : 126365 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 506-59-2
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 4), H302 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Warning Hazard statement(s) H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.
Aldrich - 126365 Page 2 of 7
Precautionary statement(s) P261 Avoid breathing dust. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Formula : C2H7N · HCl
Molecular weight : 81.54 g/mol CAS-No. : 506-59-2 EC-No. : 208-046-5 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Aldrich - 126365 Page 3 of 7
5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
hygroscopic Storage class (TRGS 510): Non Combustible Solids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact
Aldrich - 126365 Page 4 of 7
Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle r (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: crystalline Colour: colourless
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Melting point/range: 170 - 173 °C - lit.
f) Initial boiling point and boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition No data available
Aldrich - 126365 Page 5 of 7
temperature
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.4 Conditions to avoid hygroscopic
10.5 Incompatible materials Oxidizing agents
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 1,070 mg/kg(Dimethylammonium chloride)
Skin corrosion/irritation No data available(Dimethylammonium chloride)
Serious eye damage/eye irritation No data available(Dimethylammonium chloride)
Respiratory or skin sensitisation No data available(Dimethylammonium chloride)
Germ cell mutagenicity No data available(Dimethylammonium chloride)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Specific target organ toxicity - single exposure Inhalation - May cause respiratory irritation.(Dimethylammonium chloride)
Specific target organ toxicity - repeated exposure No data available
Aldrich - 126365 Page 6 of 7
Aspiration hazard No data available(Dimethylammonium chloride)
Additional Information RTECS: IQ0220000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Dimethylammonium chloride)
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Dimethylammonium chloride)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
Aldrich - 126365 Page 7 of 7
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 522805 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : 4-(Dimethylamino)pyridine
Product Number : 522805 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 1122-58-3
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 3), H301 Acute toxicity, Dermal (Category 2), H310 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H301 Toxic if swallowed. H310 Fatal in contact with skin. H315 Causes skin irritation.
Aldrich - 522805 Page 2 of 7
H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statement(s) P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse
mouth. P302 + P352 + P310 IF ON SKIN: Wash with plenty of water. Immediately call a POISON
CENTER/doctor. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P337 + P313 If eye irritation persists: Get medical advice/ attention. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Synonyms : DMAP
Formula : C7H10N2
Molecular weight : 122.17 g/mol CAS-No. : 1122-58-3 EC-No. : 214-353-5 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Aldrich - 522805 Page 3 of 7
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx)
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Aldrich - 522805 Page 4 of 7
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (EN 143) respirator cartridges as a backup to engineering controls. If th full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: crystalline Colour: beige
b) Odour No data available
c) Odour Threshold No data available
d) pH 11.14 at 5 °C
e) Melting point/freezing point
Melting point/range: 108 - 110 °C
f) Initial boiling point and boiling range
162 °C at 67 hPa
g) Flash point 110 °C - closed cup
Aldrich - 522805 Page 5 of 7
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure 0.169 hPa at 25 °C
l) Vapour density No data available
m) Relative density No data available
n) Water solubility 76 g/l at 20 °C
o) Partition coefficient: n-octanol/water
log Pow: 1.34
p) Auto-ignition temperature
420 °C
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Dissociation constant 10.14 at 5 °C
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx) In the event of fire: see section 5
Skin corrosion/irritation Irritating to skin.(N,N-Dimethylpyridin-4-amine)
Aldrich - 522805 Page 6 of 7
Serious eye damage/eye irritation Irritating to eyes.(N,N-Dimethylpyridin-4-amine)
Respiratory or skin sensitisation Buehler Test(N,N-Dimethylpyridin-4-amine) Result: Does not cause skin sensitisation.
Germ cell mutagenicity No data available(N,N-Dimethylpyridin-4-amine)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(N,N-Dimethylpyridin-4-amine)
Specific target organ toxicity - single exposure Inhalation - May cause respiratory irritation.(N,N-Dimethylpyridin-4-amine)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(N,N-Dimethylpyridin-4-amine)
Additional Information RTECS: US9230000 Weakness, Convulsions(N,N-Dimethylpyridin-4-amine)
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No bioaccumulation is to be expected (log Pow <= 4).
12.4 Mobility in soil No data available(N,N-Dimethylpyridin-4-amine)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Dissolve or mix the material with a combustible solvent and burn in a chem scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
Aldrich - 522805 Page 7 of 7
SECTION 14: Transport information
14.1 UN number ADR/RID: 2811 IMDG: 2811 IATA: 2811
14.3 Transport hazard class(es) ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H301 Toxic if swallowed. H310 Fatal in contact with skin. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 270989 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Ethyl acetate
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Eye irritation (Category 2), H319 Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H319 Causes serious eye irritation. H336 May cause drowsiness or dizziness. Precautionary statement(s) P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking.
Sigma-Aldrich - 270989 Page 2 of 8
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P370 + P378 In case of fire: Use dry powder or dry sand to extinguish. P403 + P235 Store in a well-ventilated place. Keep cool. Supplemental Hazard information (EU) EUH066 Repeated exposure may cause skin dryness or cracking.
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
Sigma-Aldrich - 270989 Page 3 of 8
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Consumers Inhalation Long-term local effects 367 mg/m3
Predicted No Effect Concentration (PNEC)
Compartment Value
Soil 0.24 mg/kg
Marine water 0.026 mg/l
Fresh water 0.26 mg/l
Marine sediment 0.125 mg/kg
Fresh water sediment 1.25 mg/kg
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Splash contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 113 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Sigma-Aldrich - 270989 Page 5 of 8
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: clear, liquid Colour: colourless
10.6 Hazardous decomposition products Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Carbon oxides In the event of fire: see section 5
Serious eye damage/eye irritation Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)(Ethyl acetate)
Respiratory or skin sensitisation No data available(Ethyl acetate)
Germ cell mutagenicity No data available(Ethyl acetate)
Carcinogenicity This product is or contains a component that is not classifiable as to its classification.(Ethyl acetate) (Ethyl acetate)
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(Ethyl acetate)
Specific target organ toxicity - single exposure May cause drowsiness or dizziness.(Ethyl acetate)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Ethyl acetate)
Additional Information RTECS: AH5425000 Inhalation of high concentrations may cause:, Headache, Drowsiness, Dizziness, Vomiting, narcosis, anemia, Central nervous system depression(Ethyl acetate) Kidney - Irregularities - Based on Human Evidence(Ethyl acetate)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Oncorhynchus mykiss (rainbow trout) - 350.00 - 600.00 mg/l - 96
12.3 Bioaccumulative potential Bioaccumulation - 3 d
(Ethyl acetate) Bioconcentration factor (BCF): 30
12.4 Mobility in soil No data available(Ethyl acetate)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1173 IMDG: 1173 IATA: 1173
14.2 UN proper shipping name ADR/RID: ETHYL ACETATE IMDG: ETHYL ACETATE IATA: Ethyl acetate
14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Sigma-Aldrich - 270989 Page 8 of 8
15.2 Chemical safety assessment A Chemical Safety Assessment has been carried out for this substance.
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
EUH066 Repeated exposure may cause skin dryness or cracking. H225 Highly flammable liquid and vapour. H319 Causes serious eye irritation. H336 May cause drowsiness or dizziness.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 03620 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Ethylenediaminetetraacetic acid
Product Number : 03620 Brand : Sigma-Aldrich Index-No. : 607-429-00-8 REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 60-00-4
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Eye irritation (Category 2), H319
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Warning Hazard statement(s) H319 Causes serious eye irritation. Precautionary statement(s) P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard none
Sigma-Aldrich - 03620 Page 2 of 7
Statements
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Formula : C10H16N2O8
Molecular weight : 292.24 g/mol CAS-No. : 60-00-4 EC-No. : 200-449-4 Index-No. : 607-429-00-8 Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Edetic acid
CAS-No. EC-No. Index-No.
60-00-4 200-449-4 607-429-00-8
Eye Irrit. 2; H319 <= 100 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx)
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
Sigma-Aldrich - 03620 Page 3 of 7
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min
Sigma-Aldrich - 03620 Page 4 of 7
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle r (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: powder Colour: white
b) Odour odourless
c) Odour Threshold No data available
d) pH 2.5 at 10 g/l at 23 °C
e) Melting point/freezing point
Melting point/range: 250 °C - dec.
f) Initial boiling point and boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density 1.46 g/cm3 at 20 °C
n) Water solubility 0.4 g/l at 20 °C
o) Partition coefficient: n-octanol/water
log Pow: 8.85 - 10.44 at 20 °C
p) Auto-ignition temperature
> 400 °C at 1,013 hPa
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
Sigma-Aldrich - 03620 Page 5 of 7
9.2 Other safety information
Dissociation constant 8.85 - 10.44 at 20 °C
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx) Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - male and female - 4,500 mg/kg(Edetic acid)
Skin corrosion/irritation Skin - Rabbit(Edetic acid) Result: No skin irritation
Respiratory or skin sensitisation Maximisation Test - Rabbit(Edetic acid) Result: Does not cause skin sensitisation.
Germ cell mutagenicity No data available(Edetic acid)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available(Edetic acid)
Specific target organ toxicity - single exposure No data available(Edetic acid)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Edetic acid)
Sigma-Aldrich - 03620 Page 6 of 7
Additional Information RTECS: AH4025000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Edetic acid)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish static test LC50 - Lepomis macrochirus (Bluegill sunfish) - 41 mg/l - 96
h(Edetic acid) Toxicity to daphnia and other aquatic invertebrates
static test EC50 - Daphnia magna (Water flea) - 625 mg/l - 48 h(Edetic acid)
12.2 Persistence and degradability
12.3 Bioaccumulative potential Bioaccumulation Lepomis macrochirus - 28 d
12.4 Mobility in soil No data available(Edetic acid)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects May be harmful to aquatic organisms due to the shift of the pH. Avoid release to the environment.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
Sigma-Aldrich - 03620 Page 7 of 7
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H319 Causes serious eye irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 284505 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : 1,2-DICHLOROETHANE, ANHYDROUS, 99.8%
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Acute toxicity, Oral (Category 4), H302 Acute toxicity, Inhalation (Category 3), H331 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Carcinogenicity (Category 1B), H350 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H302 Harmful if swallowed. H315 Causes skin irritation.
Sigma-Aldrich - 284505 Page 2 of 8
H319 Causes serious eye irritation. H331 Toxic if inhaled. H335 May cause respiratory irritation. H350 May cause cancer. Precautionary statement(s) P201 Obtain special instructions before use. P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P370 + P378 In case of fire: Use dry powder or dry sand to extinguish. P403 + P235 Store in a well-ventilated place. Keep cool. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Sigma-Aldrich - 284505 Page 3 of 8
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Hydrogen chloride gas
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid exposure - obtain special instructions before use.Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Sigma-Aldrich - 284505 Page 4 of 8
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Fluorinated rubber Minimum layer thickness: 0.7 mm Break through time: 480 min Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M) Splash contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 62 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: clear, liquid Colour: colourless
b) Odour No data available
Sigma-Aldrich - 284505 Page 5 of 8
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Melting point/range: -35 °C - lit.
f) Initial boiling point and boiling range
83 °C - lit.
g) Flash point 13.0 °C - closed cup - Tested according to Annex V of Directive 67/548/EEC.
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen chloride gas Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 670.0 mg/kg(Ethylene dichloride) LC50 Inhalation - Rat - 4 h - 3.879 mg/l(Ethylene dichloride) LD50 Dermal - Rabbit - 2,800 mg/kg(Ethylene dichloride) Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and Taste):Eye:Lacrimation.
Respiratory or skin sensitisation No data available(Ethylene dichloride)
Germ cell mutagenicity Laboratory experiments have shown mutagenic effects.(Ethylene dichloride) Ames test(Ethylene dichloride) S. typhimurium Result: positive
Carcinogenicity This product is or contains a component that has been reported to be proba EPA classification.(Ethylene dichloride) Possible human carcinogen(Ethylene dichloride)
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Ethylene dichloride)
Reproductive toxicity
Specific target organ toxicity - single exposure May cause respiratory irritation.(Ethylene dichloride)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Ethylene dichloride)
Additional Information RTECS: KI0525000 Acts as a simple asphyxiant by displacing air., anesthetic effects, Difficulty in breathing, Headache, Dizziness, Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred vision, Provokes tears., Effects due to ingestion may include:, Gastrointestinal discomfort, Central nervous system depression, Paresthesia., Drowsiness, Convulsions, Conjunctivitis., Pulmonary edema. Effects may be delayed., Irregular breathing., Stomach/intestinal
Sigma-Aldrich - 284505 Page 7 of 8
disorders, Nausea, Vomiting, Increased liver enzymes., Weakness, Heavy or prolonged skin exposure may result in the absorption of harmful amounts of material.(Ethylene dichloride) Pancreas. - (Ethylene dichloride)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Oncorhynchus mykiss (rainbow trout) - 225.00 mg/l - 96 h(Ethylene
12.4 Mobility in soil No data available(Ethylene dichloride)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1184 IMDG: 1184 IATA: 1184
14.2 UN proper shipping name ADR/RID: ETHYLENE DICHLORIDE IMDG: ETHYLENE DICHLORIDE IATA: Ethylene dichloride
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Authorisations and/or restrictions on use 15.2 Chemical safety assessment
For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H225 Highly flammable liquid and vapour. H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H331 Toxic if inhaled. H335 May cause respiratory irritation. H350 May cause cancer.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 451649 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Iron(III) chloride
Product Number : 451649 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 7705-08-0
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Corrosive to metals (Category 1), H290 Acute toxicity, Oral (Category 4), H302 Skin irritation (Category 2), H315 Serious eye damage (Category 1), H318
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H290 May be corrosive to metals. H302 Harmful if swallowed. H315 Causes skin irritation. H318 Causes serious eye damage.
Aldrich - 451649 Page 2 of 7
Precautionary statement(s) P280 Wear protective gloves/ eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Synonyms : Ferric chloride
Formula : Cl<SB>3</>Fe Molecular weight : 162.20 g/mol CAS-No. : 7705-08-0 EC-No. : 231-729-4 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Aldrich - 451649 Page 3 of 7
5.2 Special hazards arising from the substance or mixture Hydrogen chloride gas, Iron oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store under inert gas. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Keep in a dry place. Storage class (TRGS 510): Non-combustible, corrosive hazardous materials
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Aldrich - 451649 Page 4 of 7
Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (EN 143) respirator cartridges as a backup to engineering controls. If th full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: powder
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Melting point/range: 304 °C
f) Initial boiling point and boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure < 1 mmHg at 20 °C 1 mmHg at 194 °C
l) Vapour density 5.60 - (Air = 1.0)
m) Relative density 2.800 g/cm3
n) Water solubility No data available
Aldrich - 451649 Page 5 of 7
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative vapour density 5.60 - (Air = 1.0)
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.4 Conditions to avoid No data available
10.5 Incompatible materials Strong oxidizing agents, Potassium, Alkali metals, Bases, Exothermic in contact with water, Forms shock-sensitive mixtures with certain other materials.
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Hydrogen chloride gas, Iron oxides Other decomposition products - No data available In the event of fire: see section 5
Respiratory or skin sensitisation No data available(Iron trichloride)
Germ cell mutagenicity No data available(Iron trichloride)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
Aldrich - 451649 Page 6 of 7
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(Iron trichloride)
Specific target organ toxicity - single exposure No data available(Iron trichloride)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Iron trichloride)
Additional Information RTECS: LJ9100000 spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, Overdose of iron compounds may have a corrosive effect on the gastrointest stricture formation. Several hours may elapse before symptoms that can in hematemesis occur. After apparent recovery a person may experience metabo Further complications may develop leading to acute liver necrosis that ca, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Iron trichloride)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 21.84 mg/l - 96 h(Iron
trichloride) Toxicity to daphnia and other aquatic invertebrates
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Iron trichloride)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Toxic to aquatic life. No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging Dispose of as unused product.
Aldrich - 451649 Page 7 of 7
SECTION 14: Transport information
14.1 UN number ADR/RID: 1773 IMDG: 1773 IATA: 1773
14.2 UN proper shipping name ADR/RID: FERRIC CHLORIDE, ANHYDROUS IMDG: FERRIC CHLORIDE, ANHYDROUS IATA: Ferric chloride, anhydrous
14.3 Transport hazard class(es) ADR/RID: 8 IMDG: 8 IATA: 8
14.4 Packaging group ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H290 May be corrosive to metals. H302 Harmful if swallowed. H315 Causes skin irritation. H318 Causes serious eye damage.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma - F8775 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Formaldehyde solution, 36.5-38%
Product Number : F8775 Brand : Sigma Index-No. : 605-001-00-5 REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 50-00-0
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 3), H301 Acute toxicity, Inhalation (Category 3), H331 Acute toxicity, Dermal (Category 3), H311 Skin corrosion (Category 1B), H314 Skin sensitisation (Category 1), H317 Germ cell mutagenicity (Category 2), H341 Carcinogenicity (Category 1B), H350 Specific target organ toxicity - single exposure (Category 1), H370 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Sigma - F8775 Page 2 of 8
Signal word Danger Hazard statement(s) H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled H314 Causes severe skin burns and eye damage. H317 May cause an allergic skin reaction. H335 May cause respiratory irritation. H341 Suspected of causing genetic defects. H350 May cause cancer. H370 Causes damage to organs. Precautionary statement(s) P201 Obtain special instructions before use. P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse
mouth. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P308 + P311 IF exposed or concerned: Call a POISON CENTER/doctor. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. Supplemental Hazard Statements
none
Restricted to professional users.
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.2 Mixtures Synonyms : Formalin
Formula : CH2O Hazardous ingredients according to Regulation (EC) No 1272/2008
>= 10 %: STOT SE 1, H370; 3 - < 10 %: STOT SE 2, H371;
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
Sigma - F8775 Page 4 of 8
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid exposure - obtain special instructions before use.Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 480 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.2 mm Break through time: 60 min Material tested:Dermatril® P (KCL 743 / Aldrich Z677388, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Sigma - F8775 Page 5 of 8
Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.4 Conditions to avoid Heat, flames and sparks.
10.5 Incompatible materials No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Skin corrosion/irritation Skin - Rabbit Result: Corrosive after 3 minutes to 1 hour of exposure - 20 h (OECD Test Guideline 404)
Serious eye damage/eye irritation Eyes - Rabbit Result: Corrosive - 7 d (OECD Test Guideline 405)
Respiratory or skin sensitisation Maximisation Test - Guinea pig Result: Causes sensitisation. May cause allergic skin reaction. (OECD Test Guideline 406)
Germ cell mutagenicity No data available
Carcinogenicity
IARC: 1 - Group 1: Carcinogenic to humans (Formaldehyde)
Reproductive toxicity No data available
Specific target organ toxicity - single exposure No data available
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available
Additional Information RTECS: LP8925000
Sigma - F8775 Page 7 of 8
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Harmful to aquatic life.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product This combustible material may be burned in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 2209 IMDG: 2209 IATA: 2209
14.2 UN proper shipping name ADR/RID: FORMALDEHYDE SOLUTION IMDG: FORMALDEHYDE SOLUTION IATA: Formaldehyde solution
14.3 Transport hazard class(es) ADR/RID: 8 IMDG: 8 IATA: 8
14.4 Packaging group ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H225 Highly flammable liquid and vapour. H301 Toxic if swallowed.
Sigma - F8775 Page 8 of 8
H301 + H311 + H331
Toxic if swallowed, in contact with skin or if inhaled
H311 Toxic in contact with skin. H314 Causes severe skin burns and eye damage. H315 Causes skin irritation. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H331 Toxic if inhaled. H335 May cause respiratory irritation. H341 Suspected of causing genetic defects. H350 May cause cancer. H370 Causes damage to organs. H371 May cause damage to organs.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 240745 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Fumaric acid
Product Number : 240745 Brand : Sigma-Aldrich Index-No. : 607-146-00-X REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 110-17-8
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Eye irritation (Category 2), H319
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Warning Hazard statement(s) H319 Causes serious eye irritation. Precautionary statement(s) P280 Wear eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Sigma-Aldrich - 240745 Page 2 of 7
P337 + P313 If eye irritation persists: Get medical advice/ attention. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Formula : C4H4O4
Molecular weight : 116.07 g/mol CAS-No. : 110-17-8 EC-No. : 203-743-0 Index-No. : 607-146-00-X Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Fumaric acid
CAS-No. EC-No. Index-No.
110-17-8 203-743-0 607-146-00-X
Eye Irrit. 2; H319 <= 100 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
Sigma-Aldrich - 240745 Page 3 of 7
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber
Sigma-Aldrich - 240745 Page 4 of 7
Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle r (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odour No data available
c) Odour Threshold No data available
d) pH 2.1 at 4.9 g/l at 20 °C
e) Melting point/freezing point
Melting point/range: 287 °C - DIN 53181
f) Initial boiling point and boiling range
No data available
g) Flash point 230 °C - closed cup - DIN 51755 Part 1
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available(Fumaric acid)
Sigma-Aldrich - 240745 Page 6 of 7
Specific target organ toxicity - single exposure No data available(Fumaric acid)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Fumaric acid)
Additional Information
Repeated dose toxicity - Rat - male - Oral - No observed adverse effect level - 600 mg/kg(Fumaric acid) RTECS: LS9625000 Gastrointestinal disturbance, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Fumaric acid)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish semi-static test LC50 - Danio rerio (zebra fish) - > 100 mg/l - 96 h(Fumaric
acid) (OECD Test Guideline 203)
Toxicity to daphnia and other aquatic invertebrates
Immobilization EC50 - Daphnia magna (Water flea) - 212 mg/l - 48 h(Fumaric acid) (OECD Test Guideline 202)
12.2 Persistence and degradability Biodegradability aerobic - Exposure time 28 d(Fumaric acid)
Result: 67.5 % - Readily biodegradable (OECD Test Guideline 301B)
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Fumaric acid)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging Dispose of as unused product.
Sigma-Aldrich - 240745 Page 7 of 7
SECTION 14: Transport information
14.1 UN number ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H319 Causes serious eye irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma - H0883 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 03.04.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Hydrazine monohydrate
Product Number : H0883 Brand : Sigma REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H301 Toxic if swallowed.
Sigma - H0883 Page 2 of 8
H312 Harmful in contact with skin. H314 Causes severe skin burns and eye damage. H317 May cause an allergic skin reaction. H330 Fatal if inhaled. H350 May cause cancer. H410 Very toxic to aquatic life with long lasting effects. Precautionary statement(s) P201 Obtain special instructions before use. P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
Restricted to professional users.
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.2 Mixtures Synonyms : Hydrazinium hydroxide
Molecular weight : 50.06 g/mol Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Hydrazine Included in the Candidate List of Substances of Very High Concern (SVHC) according to Regulation (EC) No. 1907/2006 (REACH)
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
Sigma - H0883 Page 3 of 8
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Nitrogen oxides (NOx)
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid exposure - obtain special instructions before use.Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
Sigma - H0883 Page 4 of 8
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Combustible liquids, toxic
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 30 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
Sigma - H0883 Page 5 of 8
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid, clear Colour: colourless
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
-51.7 °C
f) Initial boiling point and boiling range
120.1 °C at 1,013 hPa
g) Flash point 74 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure 5 mmHg at 25 °C
l) Vapour density 1.73 - (Air = 1.0)
m) Relative density 1.032 g/cm3
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative vapour density 1.73 - (Air = 1.0)
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Nitrogen oxides (NOx) In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity No data available
Skin corrosion/irritation No data available
Serious eye damage/eye irritation No data available
Respiratory or skin sensitisation No data available
Germ cell mutagenicity No data available
Carcinogenicity
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Hydrazine)
Reproductive toxicity No data available
Specific target organ toxicity - single exposure No data available
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available
Additional Information RTECS: Not available CNS stimulation., Cyanosis, Salivation, Seizures., Diarrhoea, Fever, Confusion., Hypoglycemia, Anorexia., Convulsions, Coma.
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Very toxic to aquatic life with long lasting effects.
Sigma - H0883 Page 7 of 8
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product This combustible material may be burned in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 2030 IMDG: 2030 IATA: 2030
14.2 UN proper shipping name ADR/RID: HYDRAZINE, AQUEOUS SOLUTION IMDG: HYDRAZINE, AQUEOUS SOLUTION IATA: Hydrazine, aqueous solution Passenger Aircraft: Not permitted for transport
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Authorisations and/or restrictions on use 15.2 Chemical safety assessment
For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H226 Flammable liquid and vapour. H301 Toxic if swallowed. H311 Toxic in contact with skin. H312 Harmful in contact with skin. H314 Causes severe skin burns and eye damage. H315 Causes skin irritation. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H330 Fatal if inhaled. H350 May cause cancer. H400 Very toxic to aquatic life. H410 Very toxic to aquatic life with long lasting effects.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge
Sigma - H0883 Page 8 of 8
and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma - H1758 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.1 Revision Date 15.07.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Hydrochloric acid
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Corrosive to metals (Category 1), H290 Skin corrosion (Category 1B), H314 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H290 May be corrosive to metals. H314 Causes severe skin burns and eye damage. H335 May cause respiratory irritation. Precautionary statement(s) P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P280 Wear protective gloves/ protective clothing/ eye protection/ face
Sigma - H1758 Page 2 of 7
protection. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.2 Mixtures Formula : HCl Molecular weight : 36.46 g/mol Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
Sigma - H1758 Page 3 of 7
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Hydrogen chloride gas Hydrogen chloride gas
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. For personal protection see section 8.
6.2 Environmental precautions Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Non-combustible, corrosive hazardous materials
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Sigma - H1758 Page 4 of 7
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid Colour: light yellow
b) Odour pungent
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
-30 °C
f) Initial boiling point and boiling range
> 100 °C - lit.
g) Flash point Not applicable
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
Sigma - H1758 Page 5 of 7
k) Vapour pressure 170 mmHg at 21.1 °C 410 mmHg at 37.7 °C
l) Vapour density No data available
m) Relative density 1.2 g/cm3 at 25 °C
n) Water solubility soluble
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.4 Conditions to avoid No data available
10.5 Incompatible materials Bases, Amines, Alkali metals, Metals, permanganates, e.g. potassium permanganate, Fluorine, metal acetylides, hexalithium disilicide
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Hydrogen chloride gas Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Hydrogen chloride gas In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity No data availableHydrochloric acid Inhalation: Inhalation may provoke the following symptoms: Respiratory irritation Cough Difficulty in breathing Pneumonia(Hydrochloric acid)
Respiratory or skin sensitisation Did not cause sensitisation on laboratory animals.(Hydrochloric acid)
Sigma - H1758 Page 6 of 7
Germ cell mutagenicity No data available(Hydrochloric acid)
Carcinogenicity This product is or contains a component that is not classifiable as to its classification.(Hydrochloric acid) (Hydrochloric acid)
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Hydrochloric acid)
Reproductive toxicity
No data available(Hydrochloric acid)
Specific target organ toxicity - single exposure The substance or mixture is classified as specific target organ toxicant, single exposure, category 3 with respiratory tract irritation.(Hydrochloric acid)
Specific target organ toxicity - repeated exposure The substance or mixture is not classified as specific target organ toxicant, repeated exposure.
Aspiration hazard No aspiration toxicity classification(Hydrochloric acid)
Additional Information RTECS: MW4025000 Inhalation of vapors may cause:, burning sensation, Cough, wheezing, Shortness of breath, spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema(Hydrochloric acid)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Lepomis macrochirus (Bluegill) - 24.6 mg/l - 96 h(Hydrochloric acid) Toxicity to daphnia and other aquatic invertebrates
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Hydrochloric acid)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects May be harmful to aquatic organisms due to the shift of the pH. Do not empty into drains.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company.
Sigma - H1758 Page 7 of 7
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1789 IMDG: 1789 IATA: 1789
14.2 UN proper shipping name ADR/RID: HYDROCHLORIC ACID IMDG: HYDROCHLORIC ACID IATA: Hydrochloric acid
14.3 Transport hazard class(es) ADR/RID: 8 IMDG: 8 IATA: 8
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H290 May be corrosive to metals. H314 Causes severe skin burns and eye damage. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 295426 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Hydrogen chloride
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Gases under pressure (Compressed gas), H280 Acute toxicity, Inhalation (Category 3), H331 Skin corrosion (Category 1A), H314
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H280 Contains gas under pressure; may explode if heated. H314 Causes severe skin burns and eye damage. H331 Toxic if inhaled. Precautionary statement(s) P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P280 Wear protective gloves/ protective clothing/ eye protection/ face
Aldrich - 295426 Page 2 of 7
protection. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
Aldrich - 295426 Page 3 of 7
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Hydrogen chloride gas
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Clean up promptly by sweeping or vacuum.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Gases
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
Aldrich - 295426 Page 4 of 7
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 30 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engine protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: Compressed gas
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Melting point/range: -114 °C - lit.
f) Initial boiling point and boiling range
-85 °C - lit.
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density 1.2 g/mL at 25 °C
n) Water solubility No data available
Aldrich - 295426 Page 5 of 7
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.4 Conditions to avoid No data available
10.5 Incompatible materials No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Hydrogen chloride gas Other decomposition products - No data available In the event of fire: see section 5
Skin corrosion/irritation Extremely corrosive and destructive to tissue.(Hydrogen chloride (press. gas))
Serious eye damage/eye irritation No data available(Hydrogen chloride (press. gas))
Respiratory or skin sensitisation No data available(Hydrogen chloride (press. gas))
Germ cell mutagenicity No data available(Hydrogen chloride (press. gas))
Carcinogenicity
Reproductive toxicity
No data available(Hydrogen chloride (press. gas))
Specific target organ toxicity - single exposure No data available(Hydrogen chloride (press. gas))
Aldrich - 295426 Page 6 of 7
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Hydrogen chloride (press. gas))
Additional Information RTECS: Not available burning sensation, Cough, wheezing, laryngitis, Shortness of breath, spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Hydrogen chloride (press. gas))
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Hydrogen chloride (press. gas))
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1050 IMDG: 1050 IATA: 1050
14.2 UN proper shipping name ADR/RID: HYDROGEN CHLORIDE, ANHYDROUS IMDG: HYDROGEN CHLORIDE, ANHYDROUS IATA: Hydrogen chloride, anhydrous Passenger Aircraft: Not permitted for transport Cargo Aircraft: Not permitted for transport
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H280 Contains gas under pressure; may explode if heated. H314 Causes severe skin burns and eye damage. H331 Toxic if inhaled.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 295396 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Hydrogen
Product Number : 295396 Brand : Aldrich Index-No. : 001-001-00-9 REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 1333-74-0
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable gases (Category 1), H220 Gases under pressure (Compressed gas), H280
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H220 Extremely flammable gas. H280 Contains gas under pressure; may explode if heated. Precautionary statement(s) P210 Keep away from heat, hot surfaces, sparks, open flames and other
Aldrich - 295396 Page 2 of 7
ignition sources. No smoking. P377 Leaking gas fire: Do not extinguish, unless leak can be stopped safely. P381 Eliminate all ignition sources if safe to do so. P410 + P403 Protect from sunlight. Store in a well-ventilated place. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Formula : H<SB>2</> Molecular weight : 2.02 g/mol CAS-No. : 1333-74-0 EC-No. : 215-605-7 Index-No. : 001-001-00-9 No components need to be disclosed according to the applicable regulations.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Flush eyes with water as a precaution.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
Aldrich - 295396 Page 3 of 7
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Clean up promptly by sweeping or vacuum.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Contents under pressure. Storage class (TRGS 510): Gases
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Splash contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 120 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374
Aldrich - 295396 Page 4 of 7
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engine protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: Compressed gas Colour: colourless
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.4 Conditions to avoid Heat, flames and sparks.
10.5 Incompatible materials Oxidizing agents
10.6 Hazardous decomposition products Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity No data availableHydrogen
Skin corrosion/irritation No data available(Hydrogen)
Serious eye damage/eye irritation No data available(Hydrogen)
Respiratory or skin sensitisation No data available(Hydrogen)
Germ cell mutagenicity No data available(Hydrogen)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(Hydrogen)
Specific target organ toxicity - single exposure No data available(Hydrogen)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Hydrogen)
Additional Information RTECS: MW8900000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Hydrogen)
Aldrich - 295396 Page 6 of 7
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Hydrogen)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1049 IMDG: 1049 IATA: 1049
14.2 UN proper shipping name ADR/RID: HYDROGEN, COMPRESSED IMDG: HYDROGEN, COMPRESSED IATA: Hydrogen, compressed Passenger Aircraft: Not permitted for transport
14.3 Transport hazard class(es) ADR/RID: 2.1 IMDG: 2.1 IATA: 2.1
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
Aldrich - 295396 Page 7 of 7
H220 Extremely flammable gas. H280 Contains gas under pressure; may explode if heated.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
SIGMA-ALDRICH Material Safety Data Sheet Date Printed: 17/AUG/2009 Date Updated: 03/AUG/2007 Version 1.6 Regulation (EC) No 1907/2006 1 - Product and Company Information Product Name HYDROGEN PEROXIDE, 30-32 WT. % SOLUTION IN WATER, SEMICONDUCTOR GRADE, 99.999% METALS BASIS Product Number 316989 Company Sigma-Aldrich Korea Ltd., 698-84 Maeng-ri, Wonsam-myun, 449-871 Yongin-city, Kyunggi-do, Technical Phone # +82-31-329-9000 Fax +82-31-329-9090 E-mail Address [email protected] 2 - Hazards Identification SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT Harmful if swallowed. Risk of serious damage to eyes. 3 - Composition/Information on Ingredients Product Name CAS # EC no Annex I Index Number HYDROGEN PEROXIDE, 30% SOLUTION 7722-84-1 231-765-0 008-003-00-9 Ingredient Name Percent CAS # EC no Annex I Index Number HYDROGEN PEROXIDE 30 7722-84-1 231-765-0 008-003-00-9 Symbols: O-C R-Phrases: 5-8-20/22-35 Heating may cause an explosion. Contact with combustible material may cause fire. Harmful by inhalation and if swallowed. Causes severe burns. WATER 70 7732-18-5 231-791-2 None Formula H2O2 Synonyms Albone 35 * Albone 50 * Albone 70 * Albone 35CG * Albone 50CG * Albone 70CG * Hydrogen peroxide, solution, 30% * Interox * Kastone * Perone 30 * Perone 35 * Perone 50 4 - First Aid Measures AFTER INHALATION If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. AFTER SKIN CONTACT In case of contact, immediately wash skin with soap and copious amounts of water.
AFTER EYE CONTACT In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician. AFTER INGESTION If swallowed, wash out mouth with water provided person is conscious. Call a physician. 5 - Fire Fighting Measures EXTINGUISHING MEDIA Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. SPECIAL RISKS Specific Hazard(s): Emits toxic fumes under fire conditions. SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. 6 - Accidental Release Measures PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL Evacuate area. PROCEDURE(S) OF PERSONAL PRECAUTION(S) Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves. METHODS FOR CLEANING UP Absorb on sand or vermiculite and place in closed containers for disposal. Ventilate area and wash spill site after material pickup is complete. 7 - Handling and Storage HANDLING Directions for Safe Handling: Do not breathe vapor. Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure. STORAGE Conditions of Storage: Keep tightly closed. Store at 2-8°C 8 - Exposure Controls / Personal Protection ENGINEERING CONTROLS Safety shower and eye bath. Mechanical exhaust required. GENERAL HYGIENE MEASURES Wash thoroughly after handling. PERSONAL PROTECTIVE EQUIPMENT Respiratory Protection: Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole SIAL - 316989 www.sigma-aldrich.com Page 2
means of protection, use a full-face supplied air respirator. Hand Protection: Compatible chemical-resistant gloves. Eye Protection: Chemical safety goggles. 9 - Physical and Chemical Properties Appearance Physical State: Clear liquid Color: Colorless Property Value At Temperature or Pressure pH N/A BP/BP Range N/A MP/MP Range N/A Flash Point N/A Flammability N/A Autoignition Temp N/A Oxidizing Properties N/A Explosive Properties N/A Explosion Limits N/A Vapor Pressure N/A SG/Density 1.11 g/cm3 Partition Coefficient N/A Viscosity N/A Vapor Density N/A Saturated Vapor Conc. N/A Evaporation Rate N/A Bulk Density N/A Decomposition Temp. N/A Solvent Content N/A Water Content N/A Surface Tension N/A Conductivity N/A Miscellaneous Data N/A Solubility N/A 10 - Stability and Reactivity STABILITY Stable: Stable. Materials to Avoid: Strong oxidizing agents. HAZARDOUS DECOMPOSITION PRODUCTS Hazardous Decomposition Products: . HAZARDOUS POLYMERIZATION Hazardous Polymerization: Will not occur 11 - Toxicological Information RTECS NUMBER: MX0899000 ACUTE TOXICITY LDLO Oral Woman 2.626 mg/kg Remarks: Gastrointestinal:Nausea or vomiting. Lungs, Thorax, or Respiration:Cyanosis. Behavioral:Coma. LDLO SIAL - 316989 www.sigma-aldrich.com Page 3
Oral Man 1429 mg/kg Remarks: Behavioral:Coma. Gastrointestinal:Changes in structure or function of esophagus. Gastrointestinal:Nausea or vomiting. LD50 Skin Rat 3000 mg/kg LD50 Intravenous Mouse >50 GM/KG LD50 Oral Rabbit 820 mg/kg Remarks: Gastrointestinal:Peritonitis. Blood:Pigmented or nucleated red bIood cells. Blood:Changes in leukocyte (WBC) count. SIGNS AND SYMPTOMS OF EXPOSURE To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. ROUTE OF EXPOSURE Skin Contact: May cause skin irritation. Skin Absorption: May be harmful if absorbed through the skin. Eye Contact: Causes severe eye irritation. Inhalation: Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled. Ingestion: Harmful if swallowed. TARGET ORGAN INFORMATION Eyes. Respiratory system. Skin. CHRONIC EXPOSURE - CARCINOGEN Result: This product is or contains a component that is not classifiable as to its carcinogenicity based on its IARC, ACGIH, NTP, or EPA classification. Mouse Route of Application: Oral Exposure Time: 2Y Result: Tumorigenic:Carcinogenic by RTECS criteria. Gastrointestinal:Tumors. Mouse Route of Application: Oral Exposure Time: 2Y Result: Gastrointestinal:Tumors. Tumorigenic:Carcinogenic by RTECS criteria. IARC CARCINOGEN LIST Rating: Group 3 CHRONIC EXPOSURE - MUTAGEN SIAL - 316989 www.sigma-aldrich.com Page 4
Human 9 UMOL/L Cell Type: lymphocyte DNA damage Human 50 UMOL/L Cell Type: Embryo Other mutation test systems Human 20 UMOL/L Cell Type: Embryo Cytogenetic analysis Rat 50 UMOL/L Cell Type: lymphocyte DNA damage Hamster 250 UMOL/L Cell Type: ovary DNA inhibition Hamster 60 UMOL/L Cell Type: ovary Cytogenetic analysis Hamster 40 UMOL/L Cell Type: ovary Sister chromatid exchange Hamster 1 MMOL/L Cell Type: lung Mutation in mammalian somatic cells. 12 - Ecological Information No data available. 13 - Disposal Considerations SUBSTANCE DISPOSAL Contact a licensed professional waste disposal service to dispose of this material. Observe all federal, state, and local environmental regulations. 14 - Transport Information RID/ADR UN#: 2014 Class: 5.1 PG: II Subrisk: 8 Proper Shipping Name: Hydrogen peroxide, aqueous solution IMDG SIAL - 316989 www.sigma-aldrich.com Page 5
UN#: 2014 Class: 5.1 PG: II Subrisk: 8 Proper Shipping Name: Hydrogen peroxide, aqueous solution Marine Pollutant: No Severe Marine Pollutant: No IATA UN#: 2014 Class: 5.1 PG: II Subrisk: 8 Proper Shipping Name: Hydrogen peroxide, aqueous solution Inhalation Packing Group I: No 15 - Regulatory Information CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES ANNEX I INDEX NUMBER: 008-003-00-9 INDICATION OF DANGER: Xn Harmful. R-PHRASES: 22-41 Harmful if swallowed. Risk of serious damage to eyes. S-PHRASES: 26-39 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear eye/face protection. COUNTRY SPECIFIC INFORMATION Germany WGK: 1 Self-Classification NORWAY Declaration Number: 68197 16 - Other Information WARRANTY The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Inc., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. Copyright 2009 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only. DISCLAIMER For R&D use only. Not for drug, household or other uses. SIAL - 316989 www.sigma-aldrich.com Page 6
Katayama - 13-2600 Page 1 of 6
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 08.11.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Hyflo® Super-Cel®
Product Number : 13-2600 Brand : Katayama REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 68855-54-9
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Specific target organ toxicity - repeated exposure (Category 2), H373
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Warning Hazard statement(s) H373 May cause damage to organs through prolonged or repeated exposure. Precautionary statement(s) none Supplemental Hazard Statements
none
Katayama - 13-2600 Page 2 of 6
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.2 Mixtures Synonyms : Celite 500 fine
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Diatomaceous earth (Calcined)
CAS-No. EC-No.
68855-54-9 272-489-0
STOT RE 2; H373 >= 90 - <= 100 %
Silicon dioxide
CAS-No. EC-No.
14464-46-1 238-455-4
STOT RE 2; H373 >= 80 - < 90 %
Quartz
CAS-No. EC-No.
14808-60-7 238-878-4
STOT RE 2; H373 >= 1 - < 10 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Flush eyes with water as a precaution.
If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Katayama - 13-2600 Page 3 of 6
5.2 Special hazards arising from the substance or mixture silicon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Katayama - 13-2600 Page 4 of 6
Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle r (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
No data available
f) Initial boiling point and boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
Katayama - 13-2600 Page 5 of 6
10.4 Conditions to avoid No data available
10.5 Incompatible materials No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - silicon oxides Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity No data available
Skin corrosion/irritation No data available
Serious eye damage/eye irritation No data available
Respiratory or skin sensitisation No data available
Germ cell mutagenicity No data available
Carcinogenicity
IARC: 1 - Group 1: Carcinogenic to humans (Silicon dioxide)
IARC: 1 - Group 1: Carcinogenic to humans (Quartz)
Reproductive toxicity No data available
Specific target organ toxicity - single exposure No data available
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available
Additional Information RTECS: Not available
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Katayama - 13-2600 Page 6 of 6
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H373 May cause damage to organs through prolonged or repeated exposure.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - W292907 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Isopropyl alcohol
Product Number : W292907 Brand : Aldrich Index-No. : 603-117-00-0 REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 67-63-0
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Eye irritation (Category 2), H319 Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H319 Causes serious eye irritation. H336 May cause drowsiness or dizziness.
Aldrich - W292907 Page 2 of 8
Precautionary statement(s) P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking. P261 Avoid breathing vapours. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Synonyms : 2-Propanol
sec-Propyl alcohol Isopropyl alcohol Isopropanol
Formula : C<SB>3</>H<SB>8</>O Molecular weight : 60.10 g/mol CAS-No. : 67-63-0 EC-No. : 200-661-7 Index-No. : 603-117-00-0 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
Aldrich - W292907 Page 3 of 8
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Handle and store under inert gas. hygroscopic Storage class (TRGS 510): Flammable Liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Aldrich - W292907 Page 4 of 8
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 480 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.2 mm Break through time: 60 min Material tested:Dermatril® P (KCL 743 / Aldrich Z677388, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 5,045 mg/kg(2-Propanol) Remarks: Behavioral:Altered sleep time (including change in righting reflex). Behavioral:Somnolence (general depressed activity). LC50 Inhalation - Rat - 8 h - 16000 ppm(2-Propanol) LD50 Dermal - Rabbit - 12,800 mg/kg(2-Propanol)
Respiratory or skin sensitisation No data available(2-Propanol)
Germ cell mutagenicity No data available(2-Propanol)
Carcinogenicity This product is or contains a component that is not classifiable as to its classification.(2-Propanol) (2-Propanol)
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (2-Propanol)
Reproductive toxicity No data available(2-Propanol)
Specific target organ toxicity - single exposure Inhalation, Oral - May cause drowsiness or dizziness.(2-Propanol)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(2-Propanol)
Additional Information RTECS: NT8050000 Central nervous system depression, prolonged or repeated exposure can cause:, Nausea, Headache, Vomiting, narcosis, Drowsiness, Overexposure may cause mild, reversible liver effects., Aspiration may lead to:, Lung oedema, Pneumonia(2-Propanol) To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(2-Propanol) Kidney - Irregularities - Based on Human Evidence(2-Propanol)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 9,640.00 mg/l - 96 h(2-
Propanol) Toxicity to daphnia and other aquatic invertebrates
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No bioaccumulation is to be expected (log Pow <= 4).
Aldrich - W292907 Page 7 of 8
12.4 Mobility in soil No data available(2-Propanol)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1219 IMDG: 1219 IATA: 1219
14.2 UN proper shipping name ADR/RID: ISOPROPANOL IMDG: ISOPROPANOL IATA: Isopropanol
14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H225 Highly flammable liquid and vapour. H319 Causes serious eye irritation. H336 May cause drowsiness or dizziness.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held
Aldrich - W292907 Page 8 of 8
liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 146455 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Isovaleraldehyde
Product Number : 146455 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 590-86-3
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Eye irritation (Category 2), H319 Skin sensitisation (Category 1), H317 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Chronic aquatic toxicity (Category 2), H411
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation.
Aldrich - 146455 Page 2 of 7
H335 May cause respiratory irritation. H411 Toxic to aquatic life with long lasting effects. Precautionary statement(s) P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. P261 Avoid breathing vapours. P273 Avoid release to the environment. P280 Wear protective gloves. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. Stench.
SECTION 3: Composition/information on ingredients
3.1 Substances Synonyms : 3-Methylbutyraldehyde
Formula : C<SB>5</>H<SB>10</>O Molecular weight : 86.13 g/mol CAS-No. : 590-86-3 EC-No. : 209-691-5 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
Aldrich - 146455 Page 3 of 7
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature 2 - 8 °C
Handle and store under inert gas. Air and light sensitive. Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Aldrich - 146455 Page 4 of 7
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Splash contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 30 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: clear, liquid Colour: colourless
b) Odour unpleasant
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
Freezing point: < -89.99 °C
f) Initial boiling point and boiling range
90 °C - lit.
g) Flash point -4.99 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower No data available
Aldrich - 146455 Page 5 of 7
flammability or explosive limits
k) Vapour pressure 30 mmHg at 20 °C
l) Vapour density 2.97 - (Air = 1.0)
m) Relative density 0.803 g/cm3 at 25 °C
n) Water solubility 15 g/l at 20 °C - OECD Test Guideline 105 - soluble
o) Partition coefficient: n-octanol/water
log Pow: 1.5 at 25 °C
p) Auto-ignition temperature
210 °C at 1,020 hPa
q) Decomposition temperature
No data available
r) Viscosity 0.69 mm2/s at 20 °C -
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative vapour density 2.97 - (Air = 1.0)
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 5,600 mg/kg(Isovaleraldehyde) Remarks: Behavioral:Somnolence (general depressed activity). LD50 Oral - Rat - 5,740 mg/kg(Isovaleraldehyde) (OECD Test Guideline 401) LC50 Inhalation - Rat - 4 h - 42,700 mg/m3(Isovaleraldehyde) Remarks: Behavioral:Altered sleep time (including change in righting reflex). Gastrointestinal:Changes in structure or function of salivary glands. LD50 Dermal - Rabbit - 2,534 mg/kg(Isovaleraldehyde) Remarks: Liver:Other changes. Prolonged skin contact may cause skin irritation and/or dermatitis.
Serious eye damage/eye irritation Eyes - Rabbit(Isovaleraldehyde) Result: Irritating to eyes. - 8 d
Respiratory or skin sensitisation The preceding data, or interpretation of data, was determined using Quantitative Structure Activity Relationship (QSAR) modeling.(Isovaleraldehyde)
Germ cell mutagenicity No data available(Isovaleraldehyde)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(Isovaleraldehyde)
Specific target organ toxicity - single exposure Inhalation - May cause respiratory irritation. - Respiratory system(Isovaleraldehyde)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Isovaleraldehyde)
Additional Information RTECS: ES3450000 Nausea, Headache, Vomiting, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Isovaleraldehyde)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 3.25 mg/l - 96
h(Isovaleraldehyde) Toxicity to daphnia and other aquatic invertebrates
12.2 Persistence and degradability Biodegradability Result: 50 % - Not readily biodegradable.
(OECD Test Guideline 301D)
12.3 Bioaccumulative potential Does not bioaccumulate.
12.4 Mobility in soil No data available(Isovaleraldehyde)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Toxic to aquatic life with long lasting effects.
Aldrich - 146455 Page 7 of 7
No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1989 IMDG: 1989 IATA: 1989
14.2 UN proper shipping name ADR/RID: ALDEHYDES, N.O.S. (Isovaleraldehyde) IMDG: ALDEHYDES, N.O.S. (Isovaleraldehyde) IATA: Aldehydes, n.o.s. (Isovaleraldehyde)
14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H225 Highly flammable liquid and vapour. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H411 Toxic to aquatic life with long lasting effects.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 471259 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Methanesulfonyl chloride
Product Number : 471259 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 124-63-0
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 2), H300 Acute toxicity, Inhalation (Category 1), H330 Acute toxicity, Dermal (Category 2), H310 Skin corrosion (Category 1B), H314 Specific target organ toxicity - single exposure (Category 3), H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H300 + H310 + H330 Fatal if swallowed, in contact with skin or if inhaled H314 Causes severe skin burns and eye damage. H335 May cause respiratory irritation.
Aldrich - 471259 Page 2 of 7
Precautionary statement(s) P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash hands thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection. P284 Wear respiratory protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor. P302 + P350 IF ON SKIN: Gently wash with plenty of soap and water. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Synonyms : Mesyl chloride
Formula : CH3ClO2S
Molecular weight : 114.55 g/mol CAS-No. : 124-63-0 EC-No. : 204-706-1 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
Aldrich - 471259 Page 3 of 7
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Sulphur oxides, Hydrogen chloride gas
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Water hydrolyzes material liberating acidic gas which in contact with meta hydrogen gas.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Handle under nitrogen, protect from moisture. Store under nitrogen. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature 2 - 8 °C
Moisture sensitive. Storage class (TRGS 510): Combustible liquids, toxic
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Aldrich - 471259 Page 4 of 7
Personal protective equipment
Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 30 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid Colour: colourless
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
No data available
f) Initial boiling point and boiling range
60 °C at 28 hPa - lit.
g) Flash point No data available
Aldrich - 471259 Page 5 of 7
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure 12 hPa at 53 °C
l) Vapour density 3.9
m) Relative density 1.48 g/cm3 at 25 °C
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative vapour density 3.9
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.4 Conditions to avoid Water hydrolyzes material liberating acidic gas which in contact with meta hydrogen gas.
10.6 Hazardous decomposition products Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Sulphur oxides, Hydrogen chloride gas In the event of fire: see section 5
Respiratory or skin sensitisation No data available(Methanesulphonyl chloride)
Germ cell mutagenicity No data available(Methanesulphonyl chloride)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(Methanesulphonyl chloride)
Specific target organ toxicity - single exposure May cause respiratory irritation.(Methanesulphonyl chloride)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Methanesulphonyl chloride)
Additional Information RTECS: PB2790000 Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Inhalation may provoke the following symptoms:, spasm, inflammation and edema of the bronchi, pulmonary edema, Aspiration or inhalation may cause chemical pneumonitis., Symptoms of exposure may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting., To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Methanesulphonyl chloride)
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(Methanesulphonyl chloride)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
Aldrich - 471259 Page 7 of 7
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 3246 IMDG: 3246 IATA: 3246
14.2 UN proper shipping name ADR/RID: METHANESULPHONYL CHLORIDE IMDG: METHANESULPHONYL CHLORIDE IATA: Methanesulphonyl chloride Passenger Aircraft: Not permitted for transport Cargo Aircraft: Not permitted for transport
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H300 Fatal if swallowed. H300 + H310 + H330
Fatal if swallowed, in contact with skin or if inhaled
H310 Fatal in contact with skin. H314 Causes severe skin burns and eye damage. H330 Fatal if inhaled. H335 May cause respiratory irritation.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 322415 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Acute toxicity, Oral (Category 3), H301 Acute toxicity, Inhalation (Category 3), H331 Acute toxicity, Dermal (Category 3), H311 Specific target organ toxicity - single exposure (Category 1), H370
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled H370 Causes damage to organs.
Sigma-Aldrich - 322415 Page 2 of 7
Precautionary statement(s) P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. P280 Wear protective gloves/ protective clothing. P302 + P352 + P312 IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if
you feel unwell. P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Call a POISON CENTER/doctor. P370 + P378 In case of fire: Use dry powder or dry sand to extinguish. P403 + P235 Store in a well-ventilated place. Keep cool. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
No components need to be disclosed according to the applicable regulations.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Flush eyes with water as a precaution.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Notes to physician Dizziness Drowsiness metabolic acidosis Blurred vision Seizures. Coma Blindness death
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
Sigma-Aldrich - 322415 Page 3 of 7
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Consumers Inhalation Long-term local effects 50 mg/m3
Predicted No Effect Concentration (PNEC)
Compartment Value
Soil 23.5 mg/kg
Marine water 15.4 mg/l
Fresh water 154 mg/l
Fresh water sediment 570.4 mg/kg
Onsite sewage treatment plant 100 mg/kg
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 31 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engine protection, use a full-face supplied air
Sigma-Aldrich - 322415 Page 5 of 7
respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
Skin corrosion/irritation
Serious eye damage/eye irritation
Respiratory or skin sensitisation
Germ cell mutagenicity
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Specific target organ toxicity - single exposure
Specific target organ toxicity - repeated exposure
Aspiration hazard
Additional Information RTECS: PC1400000
SECTION 12: Ecological information
12.1 Toxicity
12.2 Persistence and degradability
12.3 Bioaccumulative potential
12.4 Mobility in soil
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Sigma-Aldrich - 322415 Page 7 of 7
12.6 Other adverse effects
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1230 IMDG: 1230 IATA: 1230
14.2 UN proper shipping name ADR/RID: METHANOL IMDG: METHANOL IATA: Methanol
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment A Chemical Safety Assessment has been carried out for this substance.
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Supelco - 33050-U Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Methanolic HCl
Product Number : 33050-U Brand : Supelco REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Corrosive to metals (Category 1), H290 Acute toxicity, Oral (Category 3), H301 Acute toxicity, Inhalation (Category 3), H331 Acute toxicity, Dermal (Category 3), H311 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Specific target organ toxicity - single exposure (Category 1), H370 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger
Supelco - 33050-U Page 2 of 8
Hazard statement(s) H225 Highly flammable liquid and vapour. H290 May be corrosive to metals. H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H370 Causes damage to organs. Precautionary statement(s) P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. P280 Wear protective gloves/ protective clothing. P302 + P352 + P312 IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if
you feel unwell. P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Call a POISON CENTER/doctor. P370 + P378 In case of fire: Use dry powder or dry sand to extinguish. P403 + P235 Store in a well-ventilated place. Keep cool. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.2 Mixtures Synonyms : Hydrochloric acidsolution
Formula : HCl Molecular weight : 36.46 g/mol Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
Supelco - 33050-U Page 3 of 8
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Hydrogen chloride gas
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.
Supelco - 33050-U Page 4 of 8
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature 2 - 8 °C Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 30 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Supelco - 33050-U Page 5 of 8
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
No data available
f) Initial boiling point and boiling range
No data available
g) Flash point 11 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen chloride gas Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity No data available
Skin corrosion/irritation No data available
Serious eye damage/eye irritation No data available
Respiratory or skin sensitisation No data available
Germ cell mutagenicity No data available
Carcinogenicity
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Hydrochloric acid)
Reproductive toxicity No data available
Specific target organ toxicity - single exposure No data available
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available
Additional Information RTECS: Not available Methyl alcohol may be fatal or cause blindness if swallowed., Cannot be made non-poisonous., Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and
Supelco - 33050-U Page 7 of 8
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 3286 IMDG: 3286 IATA: 3286
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H225 Highly flammable liquid and vapour. H290 May be corrosive to metals. H301 Toxic if swallowed. H301 + H311 + H331
Toxic if swallowed, in contact with skin or if inhaled
H311 Toxic in contact with skin. H314 Causes severe skin burns and eye damage. H315 Causes skin irritation. H319 Causes serious eye irritation. H331 Toxic if inhaled. H335 May cause respiratory irritation. H370 Causes damage to organs. H371 May cause damage to organs.
Supelco - 33050-U Page 8 of 8
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 69880 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : Morpholine
Product Number : 69880 Brand : Sigma-Aldrich Index-No. : 613-028-00-9 REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 110-91-8
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H226 Flammable liquid and vapour. H302 Harmful if swallowed.
Sigma-Aldrich - 69880 Page 2 of 8
H311 + H331 Toxic in contact with skin or if inhaled. H314 Causes severe skin burns and eye damage. Precautionary statement(s) P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P370 + P378 In case of fire: Use dry powder or dry sand to extinguish. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Synonyms : Tetrahydro-1,4-oxazine
Formula : C4H9NO
Molecular weight : 87.12 g/mol CAS-No. : 110-91-8 EC-No. : 203-815-1 Index-No. : 613-028-00-9 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Sigma-Aldrich - 69880 Page 3 of 8
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx)
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
hygroscopic Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Sigma-Aldrich - 69880 Page 4 of 8
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx) Other decomposition products - No data available In the event of fire: see section 5
Sigma-Aldrich - 69880 Page 6 of 8
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - male and female - 1,900 mg/kg(Morpholine) (OECD Test Guideline 401) LD50 Dermal - Rabbit - male - 500 mg/kg(Morpholine) (OECD Test Guideline 402)
Skin corrosion/irritation Skin - Rabbit(Morpholine) Result: Causes severe burns. (OECD Test Guideline 404)
Respiratory or skin sensitisation Buehler Test - Guinea pig(Morpholine) Result: Did not cause sensitisation on laboratory animals.
Germ cell mutagenicity unscheduled DNA synthesis assay(Morpholine) rat hepatocytes Result: negative (Morpholine) Hamster - female Result: negative
Carcinogenicity
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Morpholine)
Reproductive toxicity
No data available(Morpholine)
Specific target organ toxicity - single exposure No data available(Morpholine)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(Morpholine)
Additional Information
Repeated dose toxicity - Rat - female - Oral - Lowest observed adverse effect level - 500 mg/kg(Morpholine) RTECS: QD6475000 Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea(Morpholine) To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.(Morpholine)
SECTION 12: Ecological information
12.1 Toxicity
Sigma-Aldrich - 69880 Page 7 of 8
Toxicity to fish static test LC50 - Oncorhynchus mykiss (rainbow trout) - 380 mg/l - 96 h(Morpholine)
Toxicity to daphnia and other aquatic invertebrates
Immobilization EC50 - Daphnia magna (Water flea) - 45 mg/l - 48 h(Morpholine) (OECD Test Guideline 202)
Toxicity to algae static test EC50 - Pseudokirchneriella subcapitata - 28 mg/l - 96 h(Morpholine)
12.2 Persistence and degradability Biodegradability aerobic - Exposure time 25 d(Morpholine)
Bioconcentration factor (BCF): < 2.8 (OECD Test Guideline 305C)
12.4 Mobility in soil No data available(Morpholine)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Harmful to aquatic life.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 2054 IMDG: 2054 IATA: 2054
14.2 UN proper shipping name ADR/RID: MORPHOLINE IMDG: MORPHOLINE IATA: Morpholine
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Sigma-Aldrich - 69880 Page 8 of 8
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H226 Flammable liquid and vapour. H302 Harmful if swallowed. H311 Toxic in contact with skin. H311 + H331 Toxic in contact with skin or if inhaled. H314 Causes severe skin burns and eye damage. H331 Toxic if inhaled.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich - 296090 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 30.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Skin irritation (Category 2), H315 Reproductive toxicity (Category 2), H361f Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336 Specific target organ toxicity - repeated exposure (Category 2), H373 Aspiration hazard (Category 1), H304 Chronic aquatic toxicity (Category 2), H411
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H304 May be fatal if swallowed and enters airways. H315 Causes skin irritation.
Sigma-Aldrich - 296090 Page 2 of 8
H336 May cause drowsiness or dizziness. H361f Suspected of damaging fertility. H373 May cause damage to organs through prolonged or repeated exposure. H411 Toxic to aquatic life with long lasting effects. Precautionary statement(s) P201 Obtain special instructions before use. P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. P273 Avoid release to the environment. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P331 Do NOT induce vomiting. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Sigma-Aldrich - 296090 Page 3 of 8
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Flash back possible over considerable distance.Container explosion may occur under fire conditions.Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Sigma-Aldrich - 296090 Page 4 of 8
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 480 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.2 mm Break through time: 59 min Material tested:Dermatril® P (KCL 743 / Aldrich Z677388, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engine protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
k) Vapour pressure 256.0 mmHg at 37.7 °C 132.0 mmHg at 20.0 °C
l) Vapour density No data available
m) Relative density 0.659 g/mL at 25 °C
n) Water solubility insoluble
o) Partition coefficient: n-octanol/water
log Pow: 3.90 - 4.11
p) Auto-ignition temperature
234.0 °C
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information No data available
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.4 Conditions to avoid Exposure to moisture may affect product quality. Heat, flames and sparks.
10.5 Incompatible materials Oxidizing agents
10.6 Hazardous decomposition products Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Carbon oxides In the event of fire: see section 5
Sigma-Aldrich - 296090 Page 6 of 8
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 25,000 mg/kg(n-Hexane) LC50 Inhalation - Rat - 4 h - 48000 ppm(n-Hexane)
Skin corrosion/irritation Irritating to skin.(n-Hexane)
Respiratory or skin sensitisation No data available(n-Hexane)
Germ cell mutagenicity No data available(n-Hexane)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Overexposure may cause reproductive disorder(s) based on tests with laboratory animals. Suspected human reproductive toxicant Suspected of damaging fertility.(n-Hexane)
Specific target organ toxicity - single exposure May cause drowsiness or dizziness.(n-Hexane)
Specific target organ toxicity - repeated exposure Ingestion - May cause damage to organs through prolonged or repeated exposure. - Nervous system
Aspiration hazard May be fatal if swallowed and enters airways.(n-Hexane)
Additional Information RTECS: MN9275000 Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred vision, Provokes tears., Effects due to ingestion may include:, Gastrointestinal discomfort, Central nervous system depression, Lung irritation, chest pain, pulmonary edema, giddiness, slowed reaction time, slurred speech, Headache, Dizziness, Drowsiness, Unconsciousness(n-Hexane)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 2.5 mg/l - 96.0 h(n-Hexane) Toxicity to daphnia and other aquatic invertebrates
12.2 Persistence and degradability No data available
Sigma-Aldrich - 296090 Page 7 of 8
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(n-Hexane)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects Toxic to aquatic life with long lasting effects.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 1208 IMDG: 1208 IATA: 1208
14.2 UN proper shipping name ADR/RID: HEXANES IMDG: HEXANES IATA: Hexanes
14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H225 Highly flammable liquid and vapour. H304 May be fatal if swallowed and enters airways. H315 Causes skin irritation. H336 May cause drowsiness or dizziness. H361f Suspected of damaging fertility. H373 May cause damage to organs through prolonged or repeated exposure. H411 Toxic to aquatic life with long lasting effects.
Sigma-Aldrich - 296090 Page 8 of 8
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma - M6762 Page 1 of 8
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 03.04.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : 1-Methyl-2-pyrrolidinone
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Reproductive toxicity (Category 1B), H360D Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H360D May damage the unborn child.
Sigma - M6762 Page 2 of 8
Precautionary statement(s) P201 Obtain special instructions before use. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. Supplemental Hazard Statements
none
Restricted to professional users.
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Wash off with soap and plenty of water. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Sigma - M6762 Page 3 of 8
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx)
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid exposure - obtain special instructions before use.Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Store under inert gas. Moisture sensitive. Storage class (TRGS 510): Combustible liquids not in Storage Class 3
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nature latex/chloroprene Minimum layer thickness: 0.6 mm Break through time: 35 min Material tested:Lapren® (KCL 706 / Aldrich Z677558, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Sigma - M6762 Page 5 of 8
Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx) Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 3,914 mg/kg(N-methyl-2-pyrrolidone) LDLO Inhalation - Rat - 4 h - > 5100 ppm(N-methyl-2-pyrrolidone) LD50 Dermal - Rabbit - 8,000 mg/kg(N-methyl-2-pyrrolidone)
Skin corrosion/irritation Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)(N-methyl-2-pyrrolidone)
Respiratory or skin sensitisation No data available(N-methyl-2-pyrrolidone)
Germ cell mutagenicity No data available(N-methyl-2-pyrrolidone)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity Damage to fetus possible(N-methyl-2-pyrrolidone)
Specific target organ toxicity - single exposure Inhalation - May cause respiratory irritation.(N-methyl-2-pyrrolidone)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(N-methyl-2-pyrrolidone)
Additional Information RTECS: UY5790000
Sigma - M6762 Page 7 of 8
prolonged or repeated exposure can cause:, Vomiting, Diarrhoea, Abdominal pain, Rats exposed to 1-methyl-2-pyrrolidinone at a concentration of 1 mg/L as a cells in the bone marrow and atrophy of the lymphoid tissues of the thymu(N-methyl-2-pyrrolidone) Bone marrow - Irregularities - Based on Human Evidence(N-methyl-2-pyrrolidone)
SECTION 12: Ecological information
12.1 Toxicity Toxicity to fish LC50 - other fish - 4,000 mg/l - 96 h(N-methyl-2-pyrrolidone) LC50 - Leuciscus idus (Golden orfe) - > 500 mg/l - 96 h(N-methyl-2-
pyrrolidone) Toxicity to daphnia and other aquatic invertebrates
12.4 Mobility in soil No data available(N-methyl-2-pyrrolidone)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product This combustible material may be burned in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
Sigma - M6762 Page 8 of 8
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Authorisations and/or restrictions on use 15.2 Chemical safety assessment
A Chemical Safety Assessment has been carried out for this substance.
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H360D May damage the unborn child.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
Aldrich - 130001 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006 Version 6.0 Revision Date 31.03.2016
Print Date 10.11.2016 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers Product name : 1-Methylpiperazine
Product Number : 130001 Brand : Aldrich REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 109-01-3
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemical Pvt Limited Industrial Area, Anekal Taluka Plot No 12, 12 Bommasandra - Jigani Link Road 560100 BANGALORE INDIA
1.4 Emergency telephone number
Emergency Phone # : +91 98802 05043
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 3), H226 Acute toxicity, Inhalation (Category 3), H331 Acute toxicity, Dermal (Category 4), H312 Skin corrosion (Category 1B), H314
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram
Signal word Danger Hazard statement(s) H226 Flammable liquid and vapour. H312 Harmful in contact with skin. H314 Causes severe skin burns and eye damage. H331 Toxic if inhaled.
protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER/doctor. Supplemental Hazard Statements
none
2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances Formula : C5H12N2
Molecular weight : 100.16 g/mol CAS-No. : 109-01-3 EC-No. : 203-639-5 Hazardous ingredients according to Regulation (EC) No 1272/2008
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed No data available
Aldrich - 130001 Page 3 of 7
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx)
5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8.
6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
hygroscopic Moisture sensitive. Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Aldrich - 130001 Page 4 of 7
Personal protective equipment
Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.4 mm Break through time: 240 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industria situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN 14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: clear, liquid Colour: light yellow
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point
No data available
f) Initial boiling point and boiling range
138 °C - lit.
Aldrich - 130001 Page 5 of 7
g) Flash point 39 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density 3.46 - (Air = 1.0)
m) Relative density 0.903 g/cm3 at 25 °C
n) Water solubility No data available
o) Partition coefficient: n-octanol/water
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative vapour density 3.46 - (Air = 1.0)
SECTION 10: Stability and reactivity
10.1 Reactivity No data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions No data available
10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx) Other decomposition products - No data available In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 2,553 mg/kg(1-Methylpiperazine) LC50 Inhalation - Mouse - 2 h - 2.7 mg/l(1-Methylpiperazine) Remarks: Behavioral:Excitement. Lungs, Thorax, or Respiration:Dyspnea.
Respiratory or skin sensitisation No data available(1-Methylpiperazine)
Germ cell mutagenicity No data available(1-Methylpiperazine)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity No data available(1-Methylpiperazine)
Specific target organ toxicity - single exposure No data available(1-Methylpiperazine)
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available(1-Methylpiperazine)
Additional Information RTECS: TM1225000 Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Aspiration or inhalation may cause chemical pneumonitis., spasm, inflammation and edema of the bronchi, Acute symptoms of overexposure include:, burning sensation, Cough, wheezing, laryngitis, Headache, Nausea, Vomiting(1-Methylpiperazine)
SECTION 12: Ecological information
12.1 Toxicity No data available
12.2 Persistence and degradability No data available
12.3 Bioaccumulative potential No data available
12.4 Mobility in soil No data available(1-Methylpiperazine)
12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects No data available
Aldrich - 130001 Page 7 of 7
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number ADR/RID: 2734 IMDG: 2734 IATA: 2734
14.4 Packaging group ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H226 Flammable liquid and vapour. H312 Harmful in contact with skin. H314 Causes severe skin burns and eye damage. H331 Toxic if inhaled.
Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
SAFETY DATA SHEET
1. IdentificationProduct Name 1-Chloro-3-nitrobenzene
Wash face, hands and any exposed skin thoroughly after handlingDo not eat, drink or smoke when using this productWear protective gloves/protective clothing/eye protection/face protectionAvoid breathing dust/fume/gas/mist/vapors/sprayUse only outdoors or in a well-ventilated area
InhalationIF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathingCall a POISON CENTER or doctor/physician
SkinIF ON SKIN: Wash with plenty of soap and waterCall a POISON CENTER or doctor/physician if you feel unwellRemove/Take off immediately all contaminated clothingWash contaminated clothing before reuse
IngestionIF SWALLOWED: Immediately call a POISON CENTER or doctor/physicianRinse mouth
StorageStore locked upStore in a well-ventilated place. Keep container tightly closed
DisposalDispose of contents/container to an approved waste disposal plant
Hazards not otherwise classified (HNOC) Toxic to aquatic life with long lasting effects
3. Composition / information on ingredients
Component CAS-No Weight %
m-Nitrochlorobenzene 121-73-3 98
4. First-aid measures
Eye Contact Immediate medical attention is required. Rinse immediately with plenty of water, also underthe eyelids, for at least 15 minutes.
Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Immediate medicalattention is required.
Inhalation Move to fresh air. If breathing is difficult, give oxygen. Immediate medical attention isrequired.
Ingestion Do not induce vomiting. Call a physician or Poison Control Center immediately.
Most important symptoms/effects No information available.
Notes to Physician Treat symptomatically
5. Fire-fighting measuresSuitable Extinguishing Media Water spray. Carbon dioxide (CO 2). Dry chemical. chemical foam.
Unsuitable Extinguishing Media No information available
Protective Equipment and Precautions for FirefightersAs in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and fullprotective gear.
NFPA
6. Accidental release measuresPersonal Precautions Ensure adequate ventilation. Use personal protective equipment.
Environmental Precautions See Section 12 for additional ecological information.
Methods for Containment and CleanUp
Sweep up or vacuum up spillage and collect in suitable container for disposal.
7. Handling and storageHandling Ensure adequate ventilation. Wear personal protective equipment. Avoid contact with skin,
eyes and clothing. Avoid dust formation. Avoid breathing dust/fume/gas/mist/vapours/spray.Avoid ingestion and inhalation.
Storage Keep in a dry, cool and well-ventilated place. Keep container tightly closed.
8. Exposure controls / personal protectionExposure Guidelines This product does not contain any hazardous materials with occupational exposure limits
established by the region specific regulatory bodies.
9. Physical and chemical propertiesPhysical State Solid
Respiratory Protection Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European StandardEN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator ifexposure limits are exceeded or if irritation or other symptoms are experienced.
Engineering Measures Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stationsand safety showers are close to the workstation location.
1-Chloro-3-nitrobenzene
Hygiene Measures Handle in accordance with good industrial hygiene and safety practice.
Flammability0
Revision Date 28-May-2015
Personal Protective Equipment
Instability0
Physical hazardsN/A
Eye/face Protection Wear appropriate protective eyeglasses or chemical safety goggles as described byOSHA's eye and face protection regulations in 29 CFR 1910.133 or European StandardEN166.
Skin and body protection Wear appropriate protective gloves and clothing to prevent skin exposure.
Endocrine Disruptor Information No information available
Other Adverse Effects The toxicological properties have not been fully investigated.
12. Ecological informationEcotoxicity Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Do not flush into surface water orsanitary sewer system. Do not allow material to contaminate ground water system. Do not empty into drains.
Component Freshwater Algae Freshwater Fish Microtox Water Flea
m-Nitrochlorobenzene 5.2 mg/L EC50 = 48 h 25 mg/L LC50 96 h 1.2 mg/LLC50 96 h 17.7 - 18.3 mg/L
Persistence and Degradability No information available
Bioaccumulation/ Accumulation No information available.
Mobility .
Component log Pow
m-Nitrochlorobenzene 2.41
13. Disposal considerationsWaste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. Chemical waste generators must also consult local, regional, andnational hazardous waste regulations to ensure complete and accurate classification.
m-Nitrochlorobenzene X - X 204-496-1 - X X X X -Legend:X - ListedE - Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA.F - Indicates a substance that is the subject of a Section 5(f) Rule under TSCA.N - Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designatedpolymer made with any free-radical initiator regardless of the amount used.P - Indicates a commenced PMN substanceR - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA.S - Indicates a substance that is identified in a proposed or final Significant New Use RuleT - Indicates a substance that is the subject of a Section 4 test rule under TSCA.XU - Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data BaseProduction and Site Reports (40 CFR 710(B).Y1 - Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater.Y2 - Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactantsthat comprises one of the eligibility criteria for the exemption rule.
U.S. Federal Regulations
TSCA 12(b) Not applicable
SARA 313 Not applicable
SARA 311/312 Hazardous CategorizationAcute Health Hazard Yes
Chronic Health Hazard No
Fire Hazard No
Sudden Release of Pressure Hazard No
Reactive Hazard No
Clean Water Act Not applicable
Clean Air Act Not applicable
OSHA Occupational Safety and Health AdministrationNot applicable
CERCLANot applicable
California Proposition 65 This product does not contain any Proposition 65 chemicals
State Right-to-Know
Component Massachusetts New Jersey Pennsylvania Illinois Rhode Island
m-Nitrochlorobenzene X - X - X
U.S. Department of Transportation
Reportable Quantity (RQ): NDOT Marine Pollutant NDOT Severe Marine Pollutant N
U.S. Department of Homeland SecurityThis product does not contain any DHS chemicals.
CanadaThis product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) andthe MSDS contains all the information required by the CPR
WHMIS Hazard Class D1A Very toxic materials
16. Other informationPrepared By Regulatory Affairs
Revision Summary This document has been updated to comply with the US OSHA HazCom 2012 Standardreplacing the current legislation under 29 CFR 1910.1200 to align with the GloballyHarmonized System of Classification and Labeling of Chemicals (GHS)
DisclaimerThe information provided on this Safety Data Sheet is correct to the best of our knowledge, information and belief at thedate of its publication. The information given is designed only as a guide for safe handling, use, processing, storage,transportation, disposal and release and is not to be considered as a warranty or quality specification. The informationrelates only to the specific material designated and may not be valid for such material used in combination with any othermaterial or in any process, unless specified in the text.
For non-emergency assistance, call: 1-281-441-4400
Section 2: Composition and Information on Ingredients
Composition:
Name CAS # % by Weight
{o-}Xylene 95-47-6 100
Toxicological Data on Ingredients: o-Xylene LD50: Not available. LC50: Not available.
Section 3: Hazards Identification
Potential Acute Health Effects: Hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of ingestion,of inhalation.
Potential Chronic Health Effects:CARCINOGENIC EFFECTS: A4 (Not classifiable for human or animal.) by ACGIH, 3 (Not classifiable for human.) by IARC.MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Classified POSSIBLE for human. DEVELOPMENTALTOXICITY: Classified Reproductive system/toxin/male [POSSIBLE]. The substance may be toxic to kidneys, liver, upperrespiratory tract, skin, eyes, central nervous system (CNS). Repeated or prolonged exposure to the substance can producetarget organs damage.
Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Get medical attention.
Skin Contact:In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminatedclothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Serious Skin Contact:Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medicalattention.
Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention.
Serious Inhalation:Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Ifbreathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. WARNING: It maybe hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled material is toxic, infectious orcorrosive. Seek medical attention.
Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar,tie, belt or waistband.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: Flammable.
Auto-Ignition Temperature: 463°C (865.4°F)
Flash Points: CLOSED CUP: 17°C (62.6°F).
Flammable Limits: LOWER: 0.9% UPPER: 6.7%
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances: Highly flammable in presence of open flames and sparks, of heat.
Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Slightly explosive in presence of openflames and sparks, of heat.
Fire Fighting Media and Instructions:Flammable liquid, insoluble in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray or fog.
Special Remarks on Fire Hazards:Vapors are heavier than air and may travel considerable distance to source of ignition and flash back. When heated todecomposition it emits acrid smoke and irritating fumes.
Special Remarks on Explosion Hazards:Explosive in the form of vapor when exposed to heat or flame. Vapors may form explosive mixtures with air. Containers mayexplode when heated. Runoff to sewer may create fire or explosion hazard
Section 6: Accidental Release Measures
Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal.
Large Spill:
p. 3
Toxic flammable liquid, insoluble or very slightly soluble in water. Keep away from heat. Keep away from sources of ignition.Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material. Do not get water inside container.Do not touch spilled material. Prevent entry into sewers, basements or confined areas; dike if needed. Call for assistance ondisposal. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and with localauthorities.
Section 7: Handling and Storage
Precautions:Keep locked up.. Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Donot ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of insufficient ventilation, wearsuitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoidcontact with skin and eyes. Keep away from incompatibles such as oxidizing agents, acids.
Storage:Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed andsealed until ready for use. Avoid all possible sources of ignition (spark or flame).
Section 8: Exposure Controls/Personal Protection
Engineering Controls:Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respectivethreshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.
Personal Protection:Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.
Exposure Limits:TWA: 434 STEL: 651 (mg/m3) from ACGIH (TLV) [United States] TWA: 100 STEL: 150 (ppm) from ACGIH (TLV) [UnitedStates] STEL: 150 (ppm) from NIOSH STEL: 655 (mg/m3) from NIOSHConsult local authorities for acceptable exposure limits.
Section 9: Physical and Chemical Properties
Physical state and appearance: Liquid. (Mobile, nonpolar liquid.)
Odor: Aromatic. Sweetish.
Taste: Not available.
Molecular Weight: 106.17 g/mole
Color: Colorless.
pH (1% soln/water): Not applicable.
Boiling Point: 144.4°C (291.9°F)
Melting Point: -25°C (-13°F)
Critical Temperature: 359°C (678.2°F)
Specific Gravity: 0.88 (Water = 1)
Vapor Pressure: 0.9 kPa (@ 20°C)
Vapor Density: 3.7 (Air = 1)
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Volatility: Not available.
Odor Threshold: 0.05 ppm
Water/Oil Dist. Coeff.: The product is more soluble in oil; log(oil/water) = 3.1
Ionicity (in Water): Not available.
Dispersion Properties:Dispersed in diethyl ether. Is not dispersed in cold water, hot water. See solubility in diethyl ether, acetone.
Solubility:Soluble in diethyl ether, acetone. Insoluble in cold water, hot water.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Heat, ignition sources, flames, incompatible materials.
Incompatibility with various substances: Reactive with oxidizing agents, acids.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity:Photochemically reactive. Incompatible with strong oxidizers(e.g. chlorine, bromine, fluorine), and strong acids (e.g. nitric acid,acetic acid).
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation.
Chronic Effects on Humans:CARCINOGENIC EFFECTS: A4 (Not classifiable for human or animal.) by ACGIH, 3 (Not classifiable for human.) by IARC.TERATOGENIC EFFECTS: Classified POSSIBLE for human. DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/male [POSSIBLE]. May cause damage to the following organs: kidneys, liver, upper respiratory tract, skin, eyes, centralnervous system (CNS).
Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans:May cause adverse reproductive effects (male) and birth defects based on animal data. 0347 Animal: embryotoxic, foetotoxic,passes through the placental barrier. 0900 Detected in maternal milk in human. Narcotic effect; may cause nervous systemdisturbances.
Special Remarks on other Toxic Effects on Humans:Acute Potential Health Efffects Skin: May cause skin irritation. May be absorbed through skin i harmful amounts. Eyes: Causessevere eye irritation. Inhalation: Causes respiratory tract and mucous membranes irritation. May affect sense organs, behavior(Central Nervous system) which may result in dizziness, general weakness, central nervous system depression, confusion,ataxia, disorientation, lethargy, drowsiness, headaches. May also affect respiration, cardiovascular system, liver, blood, anddigestive system (nausea, vomiting) Ingestion: Harmful if swallowed. Causes digestive tract irritation with nausea, vomiting
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and diarrhea. May also affect metabolism, liver, and urinary system, and central nervous system (excitement followed byheadache, dizziness, drowsiness and nausea). Chronic Potential Health Effects: Skin: Prolonged or repeated contact maycause defatting of skin and dermatitis. Eyes: Prolonged or repeated exposure may cause conjunctivitis or permanent eyedamage. Inhalation: Chronic inhalation may cause effects similar to those of acute inhalation.
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal:Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT Classification: CLASS 3: Flammable liquid.
Identification: : Xylene UNNA: 1307 PG: III
Special Provisions for Transport: Not available.
Section 15: Other Regulatory Information
Federal and State Regulations:Connecticut hazardous material survey.: o-Xylene Illinois chemical safety act: o-Xylene New York release reporting list: o-Xylene Pennsylvania RTK: o-Xylene Florida: o-Xylene Massachusetts RTK: o-Xylene Massachusetts spill list: o-Xylene NewJersey: o-Xylene New Jersey spill list: o-Xylene Louisiana spill reporting: o-Xylene California Director's List of HazardousSubstances: o-Xylene TSCA 8(b) inventory: o-Xylene TSCA 8(d) H and S data reporting: o-Xylene: Effective: 10/4/82; Sunset:10/4/92 SARA 313 toxic chemical notification and release reporting: o-Xylene CERCLA: Hazardous substances.: o-Xylene:1000 lbs. (453.6 kg)
Other Regulations:OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This product is on theEuropean Inventory of Existing Commercial Chemical Substances.
Other Classifications:
WHMIS (Canada):CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F). CLASS D-2A: Material causing other toxic effects(VERY TOXIC).
DSCL (EEC):
HMIS (U.S.A.):
Health Hazard: 2
Fire Hazard: 3
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Reactivity: 0
Personal Protection: h
National Fire Protection Association (U.S.A.):
Health: 2
Flammability: 3
Reactivity: 0
Specific hazard:
Protective Equipment:Gloves. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respiratorwhen ventilation is inadequate. Splash goggles.
The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assumeno liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.
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Material Safety Data SheetPalladium on Charcoal (5-10%) MSDS
Section 1: Chemical Product and Company Identification
Product Name: Palladium on Charcoal (5-10%)
Catalog Codes: SLP1597, SLP3406
CAS#: Mixture.
RTECS: Not applicable.
TSCA: TSCA 8(b) inventory: Palladium; Charcoal
CI#: Not applicable.
Synonym:
Chemical Name: Not applicable.
Chemical Formula: Not applicable.
Contact Information:
Sciencelab.com, Inc.14025 Smith Rd.Houston, Texas 77396
US Sales: 1-800-901-7247International Sales: 1-281-441-4400
For non-emergency assistance, call: 1-281-441-4400
Section 2: Composition and Information on Ingredients
Composition:
Name CAS # % by Weight
Palladium 7440-05-3 5-10
Charcoal 7440-44-0 90-95
Toxicological Data on Ingredients: Palladium LD50: Not available. LC50: Not available. Charcoal LD50: Not available.LC50: Not available.
Section 3: Hazards Identification
Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, ofinhalation.
Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to lungs, mucous membranes. Repeated or prolongedexposure to the substance can produce target organs damage.
Section 4: First Aid Measures
Eye Contact: No known effect on eye contact, rinse with water for a few minutes.
Skin Contact:After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with runningwater and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with anemollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing.
Serious Skin Contact: Not available.
Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
Serious Inhalation:Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Ifbreathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medicalattention.
Ingestion:Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, performmouth-to-mouth resuscitation. Seek immediate medical attention.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: Flammable.
Auto-Ignition Temperature: Not available.
Flash Points: Not available.
Flammable Limits: Not available.
Products of Combustion: Some metallic oxides.
Fire Hazards in Presence of Various Substances: Not available.
Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available.
Fire Fighting Media and Instructions:Flammable solid. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray or fog. Cool containing vesselswith water jet in order to prevent pressure build-up, autoignition or explosion.
Special Remarks on Fire Hazards: Material in powder form, capable of creating a dust explosion. (Charcoal)
Special Remarks on Explosion Hazards: Not available.
Section 6: Accidental Release Measures
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill:Spontaneously combustible solid. Stop leak if without risk. Absorb with an inert material and put the spilled material in anappropriate waste disposal. Obtain advice on use of water as spilled material may react with it. Do not touch spilled material.Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition sources. Cover with wet earth,sand or other non-combustible material. Call for assistance on disposal. Be careful that the product is not present at aconcentration level above TLV. Check TLV on the MSDS and with local authorities.
Section 7: Handling and Storage
Precautions:Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not breathe dust.
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Storage:Flammable materials should be stored in a separate safety storage cabinet or room. Keep away from heat. Keep away fromsources of ignition. Keep container tightly closed. Keep in a cool, well-ventilated place. Ground all equipment containingmaterial. Keep container dry. Keep in a cool place.
Section 8: Exposure Controls/Personal Protection
Engineering Controls:Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommendedexposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminantsbelow the exposure limit.
Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.Gloves.
Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.
Exposure Limits:Charcoal TWA: 3.5 (mg/m3) from ACGIH (TLV)Consult local authorities for acceptable exposure limits.
Section 9: Physical and Chemical Properties
Physical state and appearance: Solid.
Odor: Not available.
Taste: Not available.
Molecular Weight: Not applicable.
Color: Dark.
pH (1% soln/water): Not applicable.
Boiling Point: Not available.
Melting Point: 3500°C (6332°F) based on data for: Charcoal. Weighted average: 3354.16°C (6069.5°F)
Critical Temperature: Not available.
Specific Gravity: Weighted average: 3.71 (Water = 1)
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
Solubility: Insoluble in cold water.
Section 10: Stability and Reactivity Data
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Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Not available.
Incompatibility with various substances: Not available.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: No.
Section 11: Toxicological Information
Routes of Entry: Not available.
Toxicity to Animals:LD50: Not available. LC50: Not available.
Chronic Effects on Humans: The substance is toxic to lungs, mucous membranes.
Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Not available.
Special Remarks on other Toxic Effects on Humans: Nuisance dust. (Charcoal)
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal:
Section 14: Transport Information
DOT Classification: CLASS 4.2: Spontaneously combustible substance.
Identification: : Carbon, activated (Charcoal) : UN1362 PG: III
Special Provisions for Transport: Not available.
Section 15: Other Regulatory Information
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Federal and State Regulations: TSCA 8(b) inventory: Palladium; Charcoal
Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
Other Classifications:
WHMIS (Canada): CLASS D-2A: Material causing other toxic effects (VERY TOXIC).
DSCL (EEC):This product is not classified according to the EU regulations.
HMIS (U.S.A.):
Health Hazard: 1
Fire Hazard: 3
Reactivity: 0
Personal Protection: E
National Fire Protection Association (U.S.A.):
Health: 1
Flammability: 3
Reactivity: 0
Specific hazard:
Protective Equipment:Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respiratorwhen ventilation is inadequate. Safety glasses.
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/10/2005 11:09 AM
Last Updated: 05/21/2013 12:00 PM
The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assumeno liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.