Good Presentation Provide well-focused research plan Keep specific aims simple … and specific Link hypotheses to specific aims Explain method to.

Good PresentationGood Presentation

Provide well-focused research plan

Keep specific aims simple … and specific

Link hypotheses to specific aims

Explain method to test every hypothesis

Don’t wander from the main theme

A conceptual model can clarify ideas

Good PresentationGood Presentation

Be realistic … not overly ambitious Discuss potential problem areas Discuss possible solutions

– Explain rationale for your decisions Be explicit Reviewers cannot read your mind …

Don’t assume they know what you intend

Good ReviewGood Review

Increase your chances of a good review

Make sure your application presents well Make sure your application goes to the

right review group* Try to keep your reviewers happy

* Consult with Program Official


Get to the right review group Title, abstract, specific aims all point to the main

goals of your project Attach a cover letter

– suggest IC and review group assignment*– outline areas of key expertise needed for appropriate

review– do not name specific reviewers

* Consult with Program Official


Keep your reviewers happy Reviewers work late at night Help them stay alert and interested Make your application easy to read and

easy to understand Convince them to advocate for your idea

– Get them on your side!

Good LuckGood Luck

Results from: Good Ideas Good Grantsmanship Good Presentation Good Review

Grant Writing Grant Writing for Success for Success

“Great science … resembles great art … an outstanding scientist has carefully selected a “subject” (the unsolved problem to attack) and the “brushes ad paints” (the research strategy and techniques), using them to skillfully create a pleasing original “painting” (a new explanation of some aspect of the natural world).”

ed. Bruce Alberts (2009) Science 326: 205

Top 10 Top 10 Common Reviewer Common Reviewer

ConcernsConcerns

……..or How Not To ..or How Not To Get DINGED!Get DINGED!

# 1 Concern# 1 Concern

There is not aThere is not a

CLEAR HYPOTHESIS, CLEAR HYPOTHESIS, oror

WELL DEFINED GOALSWELL DEFINED GOALS

Provide a focused hypothesis, objectivesProvide a focused hypothesis, objectives Describe the importance and relevance of your Describe the importance and relevance of your

problemproblem Be clear on how your project will move the field Be clear on how your project will move the field

forwardforward

Grant 1Grant 1

HypothesisHypothesis: The proposed research seeks to examine : The proposed research seeks to examine the relationship between the relationship between neurotransmitter Aneurotransmitter A and and neurotransmitter Bneurotransmitter B signaling in B signaling in Brain Region of Interestrain Region of Interest and in vivo electrophysiological measures of Band in vivo electrophysiological measures of Brain ROIrain ROI output during the transition from chronic morphine output during the transition from chronic morphine exposure to morphine withdrawal…..additionally seeks to exposure to morphine withdrawal…..additionally seeks to determine whether putative determine whether putative Brain ROIBrain ROI projection neurons projection neurons exhibit altered basal and behaviorally-correlated firing exhibit altered basal and behaviorally-correlated firing profiles during these states……..finally seeks to profiles during these states……..finally seeks to determine whether the observed behavioral, determine whether the observed behavioral, neurochemical, and neurophysiological indices neurochemical, and neurophysiological indices associated with morphine dependence and withdrawal associated with morphine dependence and withdrawal are dependent on are dependent on Neurotransmitter ANeurotransmitter A projections to the projections to the BBrain ROI.rain ROI.

Grant 1Grant 1

SA #1SA #1: : Examine alterations in BExamine alterations in Brain ROIrain ROI neurotransmitter neurotransmitter AA and and neurotransmitter Bneurotransmitter B efflux in response to acute efflux in response to acute morphine challenge and withdrawal in morphine-morphine challenge and withdrawal in morphine-dependent ratsdependent rats

SA #2SA #2: : Examine alterations in Examine alterations in Brain ROIBrain ROI single-unit single-unit neuronal activity in response to acute morphine neuronal activity in response to acute morphine challenge….challenge….

SA #3SA #3: : Determine the sensitivity of withdrawal-associated Determine the sensitivity of withdrawal-associated neurotransmitter Aneurotransmitter A efflux, single unit neuronal activity, efflux, single unit neuronal activity, and withdrawal-associated behaviors to lesions of the and withdrawal-associated behaviors to lesions of the neurotransmitter A afferent inputsneurotransmitter A afferent inputs

Grant 1Grant 1

Reviewer CommentsReviewer Comments::

1.1. This application appears to lack a hypothesis This application appears to lack a hypothesis driven from a specific mechanism.driven from a specific mechanism.

2.2. Enthusiasm … dampened by the lack of a Enthusiasm … dampened by the lack of a specific mechanismspecific mechanism

3.3. ……..the proposal begins to look more like a ..the proposal begins to look more like a collection of experiments where the applicants collection of experiments where the applicants are simply listing experiments according to are simply listing experiments according to their expertise in specific techniquestheir expertise in specific techniques

4.4. …….overambitious nature of the project.overambitious nature of the project


The The SPECIFIC AIMSSPECIFIC AIMS do NOT TEST do NOT TEST the Hypothesis,the Hypothesis,

The The SPECIFIC AIMSSPECIFIC AIMS DEPEND on DEPEND on results from previous aimsresults from previous aims

The best proposals are those with independent The best proposals are those with independent specific aims that address your hypothesis using specific aims that address your hypothesis using different approachesdifferent approaches

Grant 2Grant 2

HypothesisHypothesis: The increase in : The increase in brainbrain receptor subunits receptor subunits after chronic morphine is an adaptation to reduced after chronic morphine is an adaptation to reduced tonic tonic neurotransmitterneurotransmitter release in the release in the brain region brain region of interestof interest and elevates the threshold for opioid and elevates the threshold for opioid analgesia.analgesia.

ObjectiveObjective: Study is to design opioid-based pain : Study is to design opioid-based pain relief paradigms with extended analgesic efficacy relief paradigms with extended analgesic efficacy and reduced risk of abuse. and reduced risk of abuse.

PurposePurpose: To determine whether : To determine whether thesethese brainbrain receptors are good targets for “anti-tolerance” receptors are good targets for “anti-tolerance” drugsdrugs

Grant 2Grant 2

SA #1SA #1: Determine the anatomical location(s) of : Determine the anatomical location(s) of chronic morphine-induced changes in chronic morphine-induced changes in brain brain receptorreceptor subunit levels subunit levels

SA #2SA #2: Examine the role of : Examine the role of brain receptor brain receptor subunitssubunits in opioid-induced behaviors other than in opioid-induced behaviors other than analgesiaanalgesia

R01R01 Requested $225,000 direct costs / 5 yearsRequested $225,000 direct costs / 5 years

Grant 2Grant 2Reviewer CommentsReviewer Comments::

1.1. Unfortunately, several of the experiments proposed do not Unfortunately, several of the experiments proposed do not directly test the hypothesis and may or may not aid in our directly test the hypothesis and may or may not aid in our further understanding of opioid tolerance.further understanding of opioid tolerance.

2.2. ..it is not clear whether such changes would correlate with ..it is not clear whether such changes would correlate with anti-nociceptive functionanti-nociceptive function

3.3. ..there is a lack of preliminary data determining whether ..there is a lack of preliminary data determining whether such studies can be accomplished and whether any such studies can be accomplished and whether any significant changes can be measuredsignificant changes can be measured

4.4. ..the literature reports 15 to 20 different mechanisms ..the literature reports 15 to 20 different mechanisms demonstrating the inhibition of opioid anti-nociceptive demonstrating the inhibition of opioid anti-nociceptive tolerance, yet none of these are addressed …tolerance, yet none of these are addressed …

5.5. ..studies proposed in aim 2 lack rationale..studies proposed in aim 2 lack rationale


The Proposal is: The Proposal is: NOT MECHANISTICNOT MECHANISTIC, , oror

NOT SCIENTIFICALLY RELEVANTNOT SCIENTIFICALLY RELEVANT

Do not propose correlative studies, propose Do not propose correlative studies, propose strong strong associationsassociations

Do not propose general observations, propose Do not propose general observations, propose specific manipulationsspecific manipulations

Grant 3Grant 3

HypothesisHypothesis: Sustained electrical activity enhances : Sustained electrical activity enhances neuronal neuronal process Xprocess X activity, targeting select proteins activity, targeting select proteins essential for synaptic vesicle essential for synaptic vesicle neurotransmitter releaseneurotransmitter release and downregulating presynaptic output in and downregulating presynaptic output in neurotransmitter Aneurotransmitter A neurons neurons

ObjectiveObjective: To define the cellular pathways initiated during : To define the cellular pathways initiated during periods of increased electrical activity to induce periods of increased electrical activity to induce subsequent decreases in synaptic outputsubsequent decreases in synaptic output

ProposePropose: : Signal TransductionSignal Transduction pathway pathway 11 acts ultimately acts ultimately to phosphorylate and protect the key presynaptic targets to phosphorylate and protect the key presynaptic targets of the of the process X structureprocess X structure

Grant 3Grant 3

SA #1SA #1: Investigate the interplay between : Investigate the interplay between process Xprocess X function and function and Signal Transduction 1Signal Transduction 1 signaling in persistent signaling in persistent neuronal plasticityneuronal plasticity

SA #2SA #2: Validate roles for the : Validate roles for the presynapticpresynaptic proteins proteins ABC1ABC1 and and ABC2ABC2 in persistent in persistent neuronal plasticityneuronal plasticity

R01R01 Requested $225,000 direct costs / 5 yearsRequested $225,000 direct costs / 5 years


1.1. ..the investigator presents an unrealistically simplistic picture of ..the investigator presents an unrealistically simplistic picture of Signal Transduction 1Signal Transduction 1 signaling in neurons signaling in neurons

2.2. The general experimental design relies on correlative studies of The general experimental design relies on correlative studies of signaling systems that are highly complex, and which act at signaling systems that are highly complex, and which act at multiple levelsmultiple levels ..

3.3. The anticipated outcomes are discussed only superficially and The anticipated outcomes are discussed only superficially and assume only that the experiments will turn out to support the assume only that the experiments will turn out to support the investigator’s hypothesis…many outcomes can be imaginedinvestigator’s hypothesis…many outcomes can be imagined

4.4. The paradigms still place the neurons in unnatural (non-The paradigms still place the neurons in unnatural (non-physiological) environments for extraordinarily long periods of physiological) environments for extraordinarily long periods of time....this model system (cultured cells) reduces the significance time....this model system (cultured cells) reduces the significance of the project because the relevance to more realistic neuronal of the project because the relevance to more realistic neuronal networks remains unclearnetworks remains unclear

5.5. ..experiments have been added which are outside the technical ..experiments have been added which are outside the technical expertise of the investigator and for which preliminary data are expertise of the investigator and for which preliminary data are not in handnot in hand

Grant 4Grant 4

HypothesisHypothesis: : Combined Treatment A/BCombined Treatment A/B group will have a group will have a greater reduction in substance use and better outcomes greater reduction in substance use and better outcomes three months after study entry, and lower HIV risk from three months after study entry, and lower HIV risk from drug or sexual behaviorsdrug or sexual behaviors

PurposePurpose: Examine the utility of a : Examine the utility of a Combined Treatment Combined Treatment A/BA/B protocol in the [ protocol in the [hospitalhospital] emergency department with ] emergency department with persons at risk for drug addiction and its associated persons at risk for drug addiction and its associated health consequenceshealth consequences

SA #1SA #1: Determine the impact of a : Determine the impact of a Combined Treatment Combined Treatment A/BA/B protocol on substance use, HIV risk reduction, protocol on substance use, HIV risk reduction, health care utilization, and health status among persons health care utilization, and health status among persons at moderate or high risk for substance abuse seeking at moderate or high risk for substance abuse seeking treatment in a [treatment in a [hospitalhospital] emergency department] emergency department

Grant 4Grant 4


1.1. The initial model of care is not different from the The initial model of care is not different from the current practice….thus, it is not clear that this current practice….thus, it is not clear that this Combined Treatment A/B protocolCombined Treatment A/B protocol will have an impact will have an impact of identifying new patients who need counseling.of identifying new patients who need counseling.

2.2. ..the significance of this ..the significance of this Combined Treatment A/BCombined Treatment A/B application is compromised by the failure to integrate application is compromised by the failure to integrate the intervention into existing practice.the intervention into existing practice.

3.3. The recruitment process is not based on a uniform The recruitment process is not based on a uniform screening protocol (lack of specifics on subject screening protocol (lack of specifics on subject recruitment, interview process, support personnel, recruitment, interview process, support personnel, follow-up strategy).follow-up strategy).


This Application is not This Application is not Appropriate for theAppropriate for the

Grant MechanismGrant Mechanism

A R21 is A R21 is NOTNOT a R01 a R01 A Career Development Award (K) is A Career Development Award (K) is NOTNOT a a

Research Project Grant (R)Research Project Grant (R)

Grant 5Grant 5

HypothesisHypothesis: Amphetamine-induced : Amphetamine-induced Behavior ABehavior A targets targets Transcription Factor XTranscription Factor X to dendritic to dendritic structures such as the spines of pyramidal cells structures such as the spines of pyramidal cells or the dendrites of interneurons of the or the dendrites of interneurons of the Brain ROIBrain ROI

SA #1SA #1: Amphetamine-induced : Amphetamine-induced Behavior ABehavior A alters alters Transcription Factor XTranscription Factor X immunoreactivity in immunoreactivity in pyramidal neurons and/or interneuronspyramidal neurons and/or interneurons

SA #2SA #2: Amphetamine-induced : Amphetamine-induced Behavior ABehavior A targets targets Transcription Factor XTranscription Factor X to dendrites and spines to dendrites and spines that receive excitatory synapsesthat receive excitatory synapses

Grant 5Grant 5


1.1. This proposal ……is somewhat novel, although mainly This proposal ……is somewhat novel, although mainly in the sense that no one previously has examined this in the sense that no one previously has examined this issue before in the issue before in the Brain ROIBrain ROI. However, in essence . However, in essence this question reflects more of an incremental advance this question reflects more of an incremental advance in our knowledge as opposed to the novel ideas in our knowledge as opposed to the novel ideas targeted by the R21 mechanism.targeted by the R21 mechanism.


The Proposal is The Proposal is

OVERLY AMBITIOUSOVERLY AMBITIOUS

Set realistic goals for the budget and project Set realistic goals for the budget and project period you proposeperiod you propose


Preliminary DataPreliminary Data is lacking is lacking

Include preliminary data for all aimsInclude preliminary data for all aims Use preliminary data to show knowledge of Use preliminary data to show knowledge of

methods and data analysesmethods and data analyses But DO propose more than just confirming But DO propose more than just confirming

preliminary resultspreliminary results


I’m not sure that the I’m not sure that the Investigator can do the Investigator can do the

PROPOSED EXPERIMENTSPROPOSED EXPERIMENTS

Don’t propose what you can’t doDon’t propose what you can’t do Include Collaborators and Consultants on your Include Collaborators and Consultants on your

projectproject Describe the value of datasets and Describe the value of datasets and

experimental modelsexperimental models


The The BackgroundBackground section is section is missing key publications and missing key publications and

experimental findingsexperimental findings

Thoroughly describe the literature, especially Thoroughly describe the literature, especially controversies, controversies, butbut

Support your views and ideasSupport your views and ideas Be sure you have found key referencesBe sure you have found key references

Grant 6Grant 6

ObjectiveObjective: Study is designed to revise and evaluate : Study is designed to revise and evaluate Intervention Model AIntervention Model A for homeless adolescents for homeless adolescents

PurposePurpose: Intervention Model A has been thoroughly : Intervention Model A has been thoroughly developed and standardized for adults, but not as well developed and standardized for adults, but not as well for adolescents, and certainly not within existing for adolescents, and certainly not within existing services. This will be a stage I, early treatment services. This will be a stage I, early treatment development project, with the aim of refining development project, with the aim of refining Intervention Intervention Model AModel A for homeless adolescents for homeless adolescents

Grant 6Grant 6 SA #1SA #1: Refine the existing : Refine the existing Intervention Model AIntervention Model A [for adults][for adults]

program to develop an integrated program to develop an integrated Intervention A and Intervention A and Intervention BIntervention B treatment program for homeless adolescents treatment program for homeless adolescents presenting symptoms of substance use disorders and self-presenting symptoms of substance use disorders and self-injury/suicidality injury/suicidality

SA #2SA #2: Examine the feasibility of delivering the : Examine the feasibility of delivering the new Integrated new Integrated Intervention programIntervention program within the context of the [ within the context of the [currently usedcurrently used] ] youth youth InterventionIntervention program recently developed …. for program recently developed …. for homeless adolescentshomeless adolescents

SA #3SA #3: Conduct a pilot study, comparing : Conduct a pilot study, comparing the new Integrated the new Integrated Invention programInvention program to Treatment-as-Usual in a randomized two to Treatment-as-Usual in a randomized two group repeated measures design, assessing clients enrolled group repeated measures design, assessing clients enrolled in [in [the currently usedthe currently used] homeless adolescent ] homeless adolescent Intervention Intervention program who are experiencing substance abuse use disorder program who are experiencing substance abuse use disorder symptoms and suicidality/self-injurious behaviorssymptoms and suicidality/self-injurious behaviors


1.1. ..the application does not provide a balanced, critical ..the application does not provide a balanced, critical review of review of Intervention Model AIntervention Model A with substance-abusing with substance-abusing adults, and why this approach would, in turn, be adults, and why this approach would, in turn, be promising with homeless youthpromising with homeless youth

2.2. ..there is an almost complete absence of focus on ..there is an almost complete absence of focus on substance abuse or the integration of substance abuse or the integration of Intervention Model Intervention Model AA [ [previouslypreviously] adapted for this problem] adapted for this problem

3.3. Other more serious design problems include different Other more serious design problems include different assessment schedules, attendance burden, and assessment schedules, attendance burden, and discharge rules between the two conditionsdischarge rules between the two conditions

4.4. ..inclusion criteria …are extremely broad…would seem ..inclusion criteria …are extremely broad…would seem to introduce enormous heterogeneity to the sample to introduce enormous heterogeneity to the sample selectedselected

5.5. What is not well-specified in the application is how the What is not well-specified in the application is how the team will decide if the results of the trial warrant the team will decide if the results of the trial warrant the move to a large efficacy trial.move to a large efficacy trial.


Experimental Details,Experimental Details,Alternative Approaches,Alternative Approaches, oror

Interpretation of DataInterpretation of Data are Inadequately Describedare Inadequately Described

Don’t assume the reviewers know the methodsDon’t assume the reviewers know the methods Provide other experimental directions you might Provide other experimental directions you might

use should you encounter problemsuse should you encounter problems Show the reviewers that you have thought about Show the reviewers that you have thought about

your research planyour research plan


The Proposal is The Proposal is

NOT RELEVANTNOT RELEVANT to the to the MISSION of the INSTITUTEMISSION of the INSTITUTE

Don’t try to make your application FIT the Don’t try to make your application FIT the Mission of a Particular InstituteMission of a Particular Institute

Funded Applications

Good Grant 1Good Grant 1

HypothesisHypothesis: : Chronic drugChronic drug exposure upregulates the exposure upregulates the expression of expression of Factor XFactor X, which triggers and sustains the , which triggers and sustains the exocytotic trafficking and surface expression of exocytotic trafficking and surface expression of functional functional Receptor AReceptor A

PurposePurpose: To investigate the molecular mechanisms for : To investigate the molecular mechanisms for FactorFactor XX-induced -induced Receptor AReceptor A trafficking trafficking


SA #1SA #1: : Determine the signaling pathways mediating Determine the signaling pathways mediating FactorFactor XX-induced R-induced Receptor Aeceptor A trafficking trafficking

SA #2SA #2: : Determine Determine Factor XFactor X involvement in involvement in drugdrug-induced -induced Receptor AReceptor A trafficking trafficking

SA #3SA #3: : Determine the synaptic sites of Determine the synaptic sites of Receptor AReceptor A trafficking and trafficking and Receptor A-BReceptor A-B interactions interactions

SA #4SA #4: : Determine the behavioral significance of emergent Determine the behavioral significance of emergent Receptor AReceptor A and behavioral and behavioral Receptor A-BReceptor A-B interactions interactions

Good Grant 1Good Grant 1Reviewer CommentsReviewer Comments::

1.1. Strengths are numerous and include novel and Strengths are numerous and include novel and innovative hypotheses, sound experimental design innovative hypotheses, sound experimental design using multidisciplinary approaches, a highly qualified using multidisciplinary approaches, a highly qualified investigator and research team, and a high likelihood investigator and research team, and a high likelihood of meaningful findingsof meaningful findings

2.2. Strengths include the significance of the central Strengths include the significance of the central hypothesis, the well-designed experimental plan, hypothesis, the well-designed experimental plan, supportive preliminary data ….supportive preliminary data ….

3.3. ..the rationale for the studies are clearly delineated, ..the rationale for the studies are clearly delineated, appropriate controls are in place, scope of the studies appropriate controls are in place, scope of the studies is appropriate, and there is … complete discussion of is appropriate, and there is … complete discussion of possible limitations of some approaches and how possible limitations of some approaches and how findings will be interpretedfindings will be interpreted


ObjectiveObjective: To use … conceptual and statistical models to : To use … conceptual and statistical models to address challenges in the development of practical address challenges in the development of practical strategies for measuring the quality of strategies for measuring the quality of communitycommunity treatmenttreatment programs programs

PurposePurpose: To extend previous approaches to casemix : To extend previous approaches to casemix adjustment for performance measurement, and the adjustment for performance measurement, and the feasibility of valid outcomes-based performance feasibility of valid outcomes-based performance measurement systems for measurement systems for community treatmentcommunity treatment..


SA #1SA #1: : Test whether Treatment Program A demonstrates Test whether Treatment Program A demonstrates efficacy under experimental conditions relative to efficacy under experimental conditions relative to community-based care programs, can be translated to a community-based care programs, can be translated to a set of community-based care programs, and is effective set of community-based care programs, and is effective relative to a set of community-based care programsrelative to a set of community-based care programs

SA #2SA #2: : Identify program features associated with good Identify program features associated with good client outcomes which might serve as indicators of the client outcomes which might serve as indicators of the quality of community-based treatment programsquality of community-based treatment programs

SA #3SA #3: : Identify candidate quality indicators appropriate for Identify candidate quality indicators appropriate for assessing the performance of community-based care assessing the performance of community-based care programs in serving key client subgroupsprograms in serving key client subgroups

Good Grant 2Good Grant 2Reviewer CommentsReviewer Comments::

1.1. The evaluation of Treatment Program A .. in real world The evaluation of Treatment Program A .. in real world settings, and the examination of efficacy, translational, settings, and the examination of efficacy, translational, and effectiveness outcomes in a single study and effectiveness outcomes in a single study represents a highly significant endeavor.represents a highly significant endeavor.

2.2. ..the approach to aim 1 is elegant..the approach to aim 1 is elegant

3.3. The study has the potential to address a major gap in The study has the potential to address a major gap in treatment services research, and to guide diffusion of treatment services research, and to guide diffusion of research-based practices to real world settingsresearch-based practices to real world settings

4.4. The solid design and measurement aspects of the The solid design and measurement aspects of the study and the innovative analytical approach ..make study and the innovative analytical approach ..make this an exciting application with the potential for high this an exciting application with the potential for high impact on the fieldimpact on the field

Three Simple Rules to remember when planning, writing and submitting your

application

DO NOT write the application for yourself

Unless you are going to fund it yourself

You MUST convince the entire review committee

and the funding agency

# 1

Reviewers are never wrong, Reviewers are never right:

they simply provide an assessment of material that you provided

in your application

Don’t Take It Personally!

# 2

The comments in the summary statement only list some of the weaknesses …. not all of the weaknesses.

When you revise your application use the time as an opportunity to improve the entire application.

# 3

More Web Resources

Funding OpportunitiesFunding Opportunities

Sites with important information:Sites with important information:

http://grants.nih.gov/grants/index.cfmhttp://grants.nih.gov/grants/index.cfm

http://grants.nih.gov/grants/welcome.htm#introductionhttp://grants.nih.gov/grants/welcome.htm#introduction

http://deainfo.nci.nih.gov/funding.htmhttp://deainfo.nci.nih.gov/funding.htm

http://deainfo.nci.nih.gov/extra/extdocs/grantrevprocess.htmhttp://deainfo.nci.nih.gov/extra/extdocs/grantrevprocess.htm

http://www.niaid.nih.gov/ncn/grants/default.htmhttp://www.niaid.nih.gov/ncn/grants/default.htm

http://www.niaid.nih.gov/ncn/grants/charts/default.htmhttp://www.niaid.nih.gov/ncn/grants/charts/default.htm

http://www.niaid.nih.gov/ncn/glossary/default.htmhttp://www.niaid.nih.gov/ncn/glossary/default.htm

grants1.nih.gov/grants/grant_tips.htm

grants.nih.gov/grants/glossary.htm

http://www3.cancer.gov/admin/gab/links.htm

deainfo.nci.nih.gov/consumer.htm

deainfo.nci.nih.gov/extra/extdocs/gntapp.htm

www.niaid.nih.gov/ncn/grants/

http://era.nih.gov/

https://commons.era.nih.gov/commons/

http://era.nih.gov/virtualschool/http://era.nih.gov/virtualschool/

grants2.nih.gov/grants/policy/nihgps_2003

grants2.nih.gov/grants/policy/nihgps_2003

http://era.nih.gov/ElectronicReceipt/

1

2

3

4

5

6

Office of Extramural Researchhttp://grants.nih.gov/grants/oer.h

tm

New “Parent” FOA page added for quick reference to unsolicited applications.

Enter search

criteria or

Select Advanced

Search

http://grants.nih.gov/grants/guide/index.html

Select the FOA number to open the announcement.

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eSubmission

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Good Presentation Provide well-focused research plan Keep specific aims simple … and specific Link hypotheses to specific aims Explain method to.

Documents

success slide

brain roi neurotransmitter

program official slide

morphine withdrawal

specific reviewers

appropriate review

field forward slide

associated neurotransmitter