Slide 1 Fig. 18.1(TE Art) Pineal gland Pituitary gland Hypothalamus Thyroid gland Thymus Adrenal glands Pancreas Testes Ovaries Gonads Parathyroid glands Slide 2 Fig. 18.3(TE Art) Endocrine system Endocrine cells Hormone in bloodstream Nervous system Slide 3 Fig. 18.1(TE Art) Pineal gland Pituitary gland Hypothalamus Thyroid gland Thymus Adrenal glands Pancreas Testes Ovaries Gonads Parathyroid glands Slide 4 hypothalamus Pituitary gland Slide 5 Slide 6 Hypothalamo- hypophyseal tract Stalk Neurohypophysis Posterior lobe Pars tuberalis Anterior lobe Adenohypophysis Pituitary gland Slide 7 Fig. 18.4a(TE Art) Hypothalamohypophyseal tract Posterior lobe Paraventricular nucleus Supraoptic nucleus Oxytocin ADH Anterior lobe Oxytocin = uterus & mammary glands Antidiuretic hormone = kidneys Slide 8 Superior hypophyseal artery Posterior pituitary Anterior pituitary Releasing hormones go and do something hormones Slide 9 Fig. 18.6(TE Art) Growth hormone ACTH TSH prolactin Liver Fat, muscle, bone LH FSH TRH GnRH CRH Hypothalamus Adrenal cortex OvaryTestis Thyroid Mammary gland IGF Slide 10 Fig. 18.10a(TE Art) Adrenal gland Kidney Adrenal cortex Adrenal medulla epinephrine norepinephrine Slide 11 Adrenal gland Kidney Adrenal cortex mineralcorticoids glucocorticoids sex steroids Adrenal medulla Aldosterone (mineralcorticoid): kidney = retain Na, excrete K (water retained, BP) Cortisol (glucocorticoid): fat & protein breakdown, glucose synthesis, fatty acid & glucose release into blood, help body adapt to stress, repair damaged tissues Dehydroepiandrosterone (DHEA): weak testosterone = libido, 2 nd sex characteristics Slide 12 Cushings Syndrome adrenal cortex hypersecretion of cortisol Slide 13 Thyroid Thymus Trachea Slide 14 Thyroid gland Follicular cells: T3 & T4 increase metabolic rate C cells: calcitonin inhibits osteoclasts.. Slide 15 Pharynx Thyroid gland Esophagus Parathyroid glands Trachea Detect low calcium Secrete PTH increase Ca absorption inhibits Ca excretion stimulates osteoclasts Posterior view Slide 16 Fig. 18.11a(TE Art) Bile duct Duodenum Head of pancreas Pancreatic ducts Body of pancreas Tail of pancreas Slide 17 Pancreatic islet cell-- insulin cell -- somatostatin cell -- glucagon Insulin: controls glucose transport into cells Diabetes Type I: low or no B-cells, no insulin Diabetes Type II: insulin insensitivity (receptor) hyperglycemia emaciation atherosclerosis (fatty deposits) ketoacidosis (low blood pH) = coma, death Slide 18 Fig. 18.1(TE Art) Pineal gland Pituitary gland Hypothalamus Thyroid gland Thymus Adrenal glands Pancreas Testes Ovaries Gonads Parathyroid glands Slide 19