Echinacea ppt1

7/31/2019 Echinacea ppt1

1/14

Does It Really Have An Immunostimulatoryeffect?!?!

ECHINACEA


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If yesPreventative OR

Treatment for

the common cold

WHAT DO YOU THINK?!?


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Commonly used in the prevention and treatment of upperrespiratory infections

Other uses includeCancer

General antiviralAnti-inflammatory

These uses currently need more data to support one side or the other

USAGE OF ECHINACEA


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One study used quan titative flow cytometry to determine themost beneficial form of extract.

They determined that water soluble is of higher quality compared tolipid soluble

Flowers, roots and leaves were used and all showed to have ef fectiveimmunostimulant characteristics

E. pallida, E. agustifolia and E. purpurea were the plants used in thisstudy

Strong evidence shows that the polysaccharide portions of Echinaceaare responsible for the immune stimulation

DOES THE PART OF THE PLANT MATTER?


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B-Lymphocytes (CD 19)

Natural Killer (CD56)

Helper T-cells, monocytes, macrophages, dendritic cells (CD4)

Cytotoxic T-Cells (C D8)

WHAT PART OF THE IMMUNE SYSTEM ISBEING STIMULATED?


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As little as 24ng/ml was proven to be immunostimulatory

Upper limit of ef fectiveness was around 1million ng/ml

HOW MUCH IS ENOUGH?


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Echinacea is not toxic You cannot overdose on it

HOWEVER exceeding the maximum concentration of 1millionng/ml reported to have a decline in stimulatory effects

CAN YOU TAKE TOO MUCH?


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Due to the lack of quality controls a specific dosage from theconsecration varies.

Currently it is best to follow the recommended dosagesDry powder: 1000mg per day

Tea: 1.5 3 grams per dayTincture: 0.75 3.75ml per day

Juice: 3 6ml per day

To avoid the immunoinhibitory effects Echinacea shouldnt betaken for more than 8 weeks at a time

HOW DOES IT ALL RELATE TO DOSAGE?


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Preventative measures or to treat the common cold.

You all said

In reality you are all

WHEN IS THE BEST TIME TO TAKE IT?


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Taking doses of Echinacea once you feel any symptoms comeon is the way to go

One study s howed acute symptoms to subside within daysafter taking an initial high dose (5-6 cups of tea containing

~1000mg day 1, then 1 cup for the next 5 days)The control group reported acute symptoms lasting 6 -10 days

ECHINACEA IS BEST USED TO TREAT THECOMMON COLD, NOT FOR PREVENTION


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Most important reason forthe use of flow cytometry

is?Convenience

Accuracy

Industry standardComparability (A)


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Echinacea is best usedprophylactically?

True

False (A)


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The most potent part ofEchinacea is?

Roots

Leaves

Lipophilic portions

Water soluble parts (A)


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http: / /www.drugs.com/npp/echinacea.html Turner, R. et a l . "Inef fect iveness of Echinacea for Prevention of

Experimental ." ANTI MICROBIAL AGENT S AND CHEMOTHERAPY (June 2006): 1708 1709.

Lindenmuth, G. et a l . "The Ef f icacy of Echinacea Compound Herbal

Tea Preparat ion on the Severi ty and Durat ion of UpperRespiratory and Flu Symptoms: A Randomized, Double-BlindPlacebo-Control led Study." THE JOU RNAL OF ALTERNATIVE

AND COMPLEMENTA RY MEDI CINE 6.4 (2000): 327 334.Linde K. , e t a l . "Echin acea for preventing and treat ing the common

cold (Review)." The Cochrane Co l l abora t ion 4 (2009): 1-52.Pi l la i , S. , e t a l . "Use of Qu anti ta t ive Flow Cytometry to Measure Ex

Vivo Immunost imulant Activi ty of Echinacea: The Case forPolysaccharides." THE JOUR NAL OF ALTERNATIVE ANDCOMPLEMENTARY MEDICINE 13.6 (2007): 625 634.

RESOURCES
http://www.drugs.com/npp/echinacea.htmlhttp://www.drugs.com/npp/echinacea.htmlhttp://www.drugs.com/npp/echinacea.html

Echinacea ppt1

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