DENGUE HEMORRHAGIC FEVER (DHF) DURGEMPUDI CHANDRA SEKHAR REDDY *, ARUN KUMAR CHADALAVADA CHEBROLU HANUMAIAH INSTITUTE OF PHARMACEUTICAL SCIENCES, CHOWDAVARAM, GUNTUR-19.
Aug 10, 2015
DENGUE HEMORRHAGIC FEVER (DHF)
DURGEMPUDI CHANDRA SEKHAR REDDY*, ARUN KUMAR CHADALAVADACHEBROLU HANUMAIAH INSTITUTE OF PHARMACEUTICAL SCIENCES,
CHOWDAVARAM, GUNTUR-19.
INTRODUCTIONDengue Hemorrhagic Fever is an acute infectious viral
disease usually affecting infants and young children.Causative agent: Aedes aegypti and Aedes albopictus.This disease used to be called break-bone fever because
it causes severe joint and muscle pain.Most favourable season for occurrence of this fever is mainly rainy season (sep &oct).
LIFE CYCLE
ETIOLOGY
Increase in urbanization in developing countries.
DHF will geographical spread by any one of four serotypes of Dengue viruses (DENV-1, 2, 3 and 4) and mainly it will spread by Aedes aegypti.
Population growth.
PATHOGENISISSIGNS & SYMPTOMS:
BRUISES CONJUNCTIVAL INFECTION
PETECHIE EPISTAXIS
UNDERLYING MECHANISM:
DIAGNOSIS:
PHYSICAL FINDINGS:HYPOTENSIONRED EYESRED THROATSWOLLEN GLANDS
TESTS INCLUDE:HEMATOCRITALTERED LIVER
ENZYMESPOSITIVE TORNIQUET
TESTSEROLOGIC STUDIES
RISK FACTORS:
• ENCEPHALOPATHY• RESIDUAL BRAIN DAMAGE• SEIZURES• LIVER DAMAGE
MANAGEMENTIsolation of patient and
treat the symptoms.Eliminate the vector by
Changing water and keeping containers closed.
Destroy breeding places of mosquitoes
Proper disposal of rubber tires, empty bottles and cans.
Residual spraying with insecticides.
REFERENCESHarrison’s Principles of Internal medicine (18 th
edition); page number:1632.http://www.authorstream.com/Presentation/
airamsherlyn-1606284-dengue-hemorrhagic-fever/http://www.slideshare.net/orlandito12/dengue-fever-
power-point?next_slideshow=1