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1. 1Custom ManufacturingCapabilities for SpecialtyChemicals,
Intermediates& APIs
2. Presentation Outline Company Overview Unique Business Model
Chemistry and Technology Analytical Services Facilities and
Equipment Competitive Advantage Contact Information
3. Company Overview Began as a New Jersey Corporation in 1995
Moved to Baltimore, Maryland in 1999 Currently 35 employees in the
U.S. operation 100% U.S. owned subsidiary in China Zhejiang
ChemPacific located near Shanghai Staffed with over 100 employees
Located on 11 acre chemical industrial park
4. Company Overview Executive TeamRebecca Chiu, MS- CEOChen
Zhou, Ph.D.- Vice PresidentTony Liang, MS and MBA- VP of
OperationsBing Li, Ph.D.- Vice President of China OperationsWuyi
Wang, Ph.D. - Senior Director of cGMP program, globalXianghui Tan,
Ph.D.- Director of cGMP ProductionJian Huang, Ph.D.- Director of
non-GMP productionJames Havlin, MBA- VP of Sales and Marketing
5. Company Overview Core Business: Research and Production of
Fine Chemicals, Industrial Chemicals, Intermediates and APIs
Resources: Research-driven U.S. Laboratories Discover and develop
products Perform small scale cGMP/ Non-GMP manufacturing up to 50kg
Cost-effective plants in China: Large scale non-GMP/cGMP
manufacturing up to 100 metric ton
6. Company OverviewR&D Contract and Custom Synthesis:
Unique Projects for Hard to Find Molecules High Levels of
Communications with Researchers Tech Transfer to China for large
scale productionCustom Manufacturing/Intermediates: Starting with
Customer Process or Just a Structure Process Development and
Optimization performed in the US Scale-Up to Commercial Quantities
performed in China
7. Unique Business Model US Facility China Facility Non-GMP and
cGMP Non-GMP and cGMP Manufacturing Manufacturing Process
Development Scale-Up Manufacturing Lab Scale (up to 1kg) Pilot
Plant (10kg to Kilo Lab (up to 10kg) 1000kg) Commercial (1 MT to
100MT) 3.
8. Chemistry and TechnologyHF and KF
FluorinationPer-fluorinated AromaticsSuzuki Coupling
OrganicsOrganometallic/Oxygen SensitiveChiral SynthesisUnnatural
Amino AcidsIndolines and IndolesHeterocyclic Synthesis
9. Chemistry and Technology Synthetic organic chemistry
expertise Non-patent-infringed process route development Experience
in handling a variety of chemistries with chiral and non-chiral
compounds Chemistry R&D and process validation Modern
Analytical facilities
10. Chemistry and TechnologyExample: Chemical Capability-
Per-fluorinated AromaticsA. Per-fluorinated BenzeneB.
Per-fluorinated Naphthalene Commercial Scale
11. Chemistry and Technology Example: Chemical Capability-
2-bromo-indene Functionization of 2-Br-IndeneA. 2-Br-Indene
Chemistry p-TSA Br Br -H2O OH Commercial Scale B. Cyclopentadiene
Chemistry Functionization Tetramethyl Cp Pentamethyl Cp
12. Chemistry and TechnologyExample: Chemical Capability-
Suzuki Coupling Organics 1. RLi handling capability (Organometallic
Chemistry Expertise) 2. Low temperature reaction and handling
capabilities
13. Facilities and EquipmentExamples of Analytical Lab
Instruments include GC GC-MS IR, UV/VIS NMR (Contract with UMBC)
Polarimeter HPLC LC-MS Prep HPLC
14. Facilities and Equipment Research & Development
Laboratory in Baltimore, MD 12,000 square ft laboratory space 50 L
Glass reaction vessel 2 L Parr reactors with pressure vessels up to
2000 PSI ChemPacific Baltimore
15. Facilities and Equipment Manufacturing Plant in
ChinaChemPacific Zhejiang: Located in a Modern Industrial Park 11
Acre site (expandable to 18 acres) Capable of Handling Complex
Projects Multi-Purpose Equipment up to 5000L -78C Reactor (300L) Up
to 1000 PSI H2 reactor (300L) High Vacuum/Thin Film Distillation
Large-Scale Column Chromatography Compartmentalized structure gives
us the capability to expand with customers market demands
16. Competitive Advantage Domestic Presence Convenience for
U.S. customers Same time zone No language barrier Secure business
practices Troubleshooting handled locally Small company Personal
attention Flexibility Quick delivery time Low overhead- pass lower
costs to our clients
17. Competitive AdvantageExperience Expertise in a wide range
of chemistries Experienced in manufacturing of hard to find
molecules Experienced technical team who recognize the challenges
of transitioning from bench to pre-scale operations. Reliable and
Financially Stable A track record of completed projects and
satisfied customers
18. Some call it the best of both worlds; we call it, The Best
of One World.