Additional Office Hour Time Every Thursday, 2-3pm in Mol Sci 4100 (the person leading this office hours will be different each week) BEGINS TOMORROW and.

Additional Office Hour TimeEvery Thursday, 2-3pm in Mol Sci 4100 (the person leading this office hours will be different each week)

BEGINS TOMORROW and will go to the end of the quarter

NMR practice problemsSources:Web Spectra: http://www.chem.ucla.edu/~webspectra/

Spectral Database of Organic Compounds (SDBS)http://riodb01.ibase.aist.go.jp/sdbs/cgi-bin/cre_index.cgiLEGEND:1H means an integration value of 1, while 2H means an intergration value of 2 etc. s = singlet d = doublet t = triplet m = multiplet

Ch14C, Spring 2012Prof. Dong

Rough 1H-NMR guidelinesAldehyde10 ppmAromatic7-9Vinylic5-7-OCH33-4Ketone ( position)2H-CC-R2-CH30-1TMS Si(CH3)40 (we use this as reference)For next several slides, the chemical structure and its 1H-NMR spectra is given to you. Please try to assign as many of the protons to the peaks shown. Confirm the following 4 features:Number of equivalent protonsChemical shiftIntegrationSplitting

Also, using the molecular formula, calculate the DBE and confirm that it matches the structure shown

Position of peak on 1H-NMR depends on the chemical environment around the protonEach of the molecules below give 1 peak on 1H-NMR because all the protons experience the same chemical environment

Beginner #7, C14H14 10H,m (overlap)4H,s

Beginner #10, C10H10O2 3H, s1H,m 1H,m1H,m1H,m1H,m1H,m1H,m

Beginner #12 C6H12O23H,s2H, t2H,pentet2H,sextet3H,t

Beginner #27, C3H7OCl 1H, s2H, t2H, t2H, pentet

Beginner #25, C4H8O 2H, q3H, s3H, t

Int1 #1, C3H4O1H,d3H (overlapping peaks)

Int2 #13, C10H15N 2H,m3H,m4H,q6H,t

Int#12, C7H9NO 4H,m2H,s3H,s

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