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PHYSIOLOGY OF EYE
BY
DR. MUDASSAR ALI ROOMI (MBBS, M.Phil.)
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Neurophysiology of Vision
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the visual system/pathwayconsists of:
the retina
The optic nerve
The optic chiasma The optic tract
The lateral geniculate body
The optic radiation
The visual cortex
The visual association cortex
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Visual Pathways to the Brain
optic nerve
axons of ganglion cells of the retina
optic chiasm
At optic chiasma, all fibers from the nasal
halves of the retina cross to the opposite side
crossed fibers join fibers from the opposite
temporal retina to form the optic tracts
These fibers synapse in the dorsallateral geniculate nucleus (LGN)
from LGN to primary visual cortex by
way of the optic radiation(geniculocalcarine tract)
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Visual pathways to the brain
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Lesions of the optic
pathway
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LESION OF OPTIC RADIATION ORGENICULOCALCARINE TRACT
Homonymouscontralateralhemianopia with
macular sparing. Macular sparing
occurs becauselesion of visual cortex
don't destroy allneurons thatrepresent themacula.
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PITUITARY TUMOR MAY COMPRESS ON OPTIC CHIASMAAND CAN CAUSE BITEMPORAL HEMIANOPIA
BITEMPORAL HEMIANOPIA
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BITEMPORAL HEMIANOPIA BINASAL HEMIANOPIA
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Lateral Geniculate Nucleus
High degree of spatial fidility
Layers II, III and V receive temporal fibers
Layers I, IV and VI receive nasal fibers
Layer I & II receive Y neurons
Layerr II & VI receive X cells
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Primary Visual Cortex????
Area 17
located in the occipitallobe in the calcarinefissure region extending tothe pole
large representation invisual cortex for the
macula (region for highestvisual acuity)
receives the primaryvisual input
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Secondary Visual Areas
visual association cortex(area 18, 19)
responsible for analyzingthe visual information
area for 3 dimensionalposition, grossform, andmotion
area for color analysis
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Retinal Projections toSubcortical Regions
suprachiasmatic nucleus of thehypothalamus
control of circadian rhythms?? pretectal nuclei
pupillary light reflex
accommodation of the lens
superior colliculus
rapid directional movement of both eyes
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The Autonomic Nerves to the Eyes
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Pupillary Light Reflexes
If a light is shone directly into oneeye, its pupil constricts. Thisresponse is known as the direct
pupillary response.
The pupil of the other eye alsoconstricts, and this is known as the
consensual response.
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PUPILLARY REFLEXES
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HORNERS SYNDROME
The sympathetic nerves to the eyeare occasionally interrupted .
Interruption occurs in cervicalsympathetic chain.
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HORNERS SYNDROME
One pupil remains persistentlyconstricted to a smaller diameter thanthe pupil of the opposite eye (miosis)
Drooping of Upper eyelid (ptosis)
Blood vessels on the corresponding side
of the face & head become persistentlydilated (flushing of face)
Sweating cant occur on the affectedside of the face (anhydrosis)
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CONFRONTATION METHOD TOTEST THE FIELD OF VISION
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perimetry
Listers perimeter
Perimetry maps andquantifies the visualfield, especially at theextreme periphery of
the visual field.
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GOLDMANS PERIMETRY
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Physiologic blind spot: In allperimetry charts, a blind spotcaused by lack of rods andcones in the retina over theoptic disc is found about 15
degrees lateral to the centralpoint of vision, as shown in thefigure.
Scotoma
A blind spot in any other
portion of the visual field
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